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Microsaccadic pursuit

MedGen UID:
334855
•Concept ID:
C1843892
•
Finding
HPO: HP:0007792

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMicrosaccadic pursuit

Conditions with this feature

Spinocerebellar ataxia type 21
MedGen UID:
375311
•Concept ID:
C1843891
•
Disease or Syndrome
Spinocerebellar ataxia-21 (SCA21) is an autosomal dominant neurologic disorder characterized by onset in the first decades of life of slowly progressive cerebellar ataxia, which is associated with cognitive impairment in most patients (summary by Delplanque et al., 2014). For a general discussion of autosomal dominant spinocerebellar ataxia, see SCA1 (164400).
See: Condition Record
Spinocerebellar ataxia type 21

Recent clinical studies

Diagnosis

Oculomotor inhibition during smooth pursuit and its dependence on contrast sensitivity.
Ziv I, Bonneh YS
J Vis 2021 Feb 3;21(2):12. doi: 10.1167/jov.21.2.12. PMID: 33630026Free PMC Article
Homozygous noncanonical splice variant in LSM1 in two siblings with multiple congenital anomalies and global developmental delay.
Okur V, LeDuc CA, Guzman E, Valivullah ZM, Anyane-Yeboa K, Chung WK
Cold Spring Harb Mol Case Stud 2019 Jun;5(3) Epub 2019 Jun 3 doi: 10.1101/mcs.a004101. PMID: 31010896Free PMC Article
Human-level saccade detection performance using deep neural networks.
Bellet ME, Bellet J, Nienborg H, Hafed ZM, Berens P
J Neurophysiol 2019 Feb 1;121(2):646-661. Epub 2018 Dec 19 doi: 10.1152/jn.00601.2018. PMID: 30565968
Saccade detection using a particle filter.
Daye PM, Optican LM
J Neurosci Methods 2014 Sep 30;235:157-68. Epub 2014 Jul 17 doi: 10.1016/j.jneumeth.2014.06.020. PMID: 25043508

Therapy

A common mechanism modulates saccade timing during pursuit and fixation.
Badler JB, Watamaniuk SNJ, Heinen SJ
J Neurophysiol 2019 Nov 1;122(5):1981-1988. Epub 2019 Sep 18 doi: 10.1152/jn.00198.2019. PMID: 31533016
Microsaccades as an overt measure of covert attention shifts.
Hafed ZM, Clark JJ
Vision Res 2002 Oct;42(22):2533-45. doi: 10.1016/s0042-6989(02)00263-8. PMID: 12445847

Prognosis

Oculomotor inhibition during smooth pursuit and its dependence on contrast sensitivity.
Ziv I, Bonneh YS
J Vis 2021 Feb 3;21(2):12. doi: 10.1167/jov.21.2.12. PMID: 33630026Free PMC Article
A common mechanism modulates saccade timing during pursuit and fixation.
Badler JB, Watamaniuk SNJ, Heinen SJ
J Neurophysiol 2019 Nov 1;122(5):1981-1988. Epub 2019 Sep 18 doi: 10.1152/jn.00198.2019. PMID: 31533016
Effects of vestibular and support afferentation upon visual pursuit in microgravity.
Kornilova L, Grigorova V, Mueller Ch, Sagalovitch SV, Alekhina M, Kozlovskaya I
J Gravit Physiol 2004 Jul;11(2):P5-7. PMID: 16229108

Clinical prediction guides

Peripheral targets attenuate miniature eye movements during fixation.
Watamaniuk SNJ, Badler JB, Heinen SJ
Sci Rep 2023 May 7;13(1):7418. doi: 10.1038/s41598-023-34066-2. PMID: 37150766Free PMC Article
Oculomotor inhibition during smooth pursuit and its dependence on contrast sensitivity.
Ziv I, Bonneh YS
J Vis 2021 Feb 3;21(2):12. doi: 10.1167/jov.21.2.12. PMID: 33630026Free PMC Article
A common mechanism modulates saccade timing during pursuit and fixation.
Badler JB, Watamaniuk SNJ, Heinen SJ
J Neurophysiol 2019 Nov 1;122(5):1981-1988. Epub 2019 Sep 18 doi: 10.1152/jn.00198.2019. PMID: 31533016
Evaluation of the Tobii EyeX Eye tracking controller and Matlab toolkit for research.
Gibaldi A, Vanegas M, Bex PJ, Maiello G
Behav Res Methods 2017 Jun;49(3):923-946. doi: 10.3758/s13428-016-0762-9. PMID: 27401169Free PMC Article

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