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Excessive Blinking

MedGen UID:
353668
•Concept ID:
C1707960
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVExcessive Blinking

Professional guidelines

PubMed

Long-term treatment of blepharospasm with botulinum toxin A: a service-based study over a 16-year follow-up in southern China.
Fang XB, Xie MS, Song ZB, Zhong ZG, Wang Y, Ou ZL, Dang C, Li L, Zhang WX
Neurol Sci 2020 Mar;41(3):645-652. Epub 2019 Nov 19 doi: 10.1007/s10072-019-04123-8. PMID: 31745757
Management of digital eye strain.
Coles-Brennan C, Sulley A, Young G
Clin Exp Optom 2019 Jan;102(1):18-29. Epub 2018 May 23 doi: 10.1111/cxo.12798. PMID: 29797453
Difficulties with differentiating botulinum toxin treatment effects in essential blepharospasm.
Wabbels B, Jost WH, Roggenkämper P
J Neural Transm (Vienna) 2011 Jun;118(6):925-43. Epub 2011 Jan 9 doi: 10.1007/s00702-010-0546-9. PMID: 21221669Free PMC Article

Recent clinical studies

Etiology

Divergence excess and basic exotropia types of intermittent exotropia: a major review. Part 1: prevalence, classification, risk factors, natural history and clinical characteristics.
Ma MM, Scheiman M
Strabismus 2023 Jun;31(2):97-128. Epub 2023 Jul 25 doi: 10.1080/09273972.2023.2227681. PMID: 37489263
Impact of femtosecond laser-assisted in situ keratomileusis on retinal ganglion cell function.
Lauzirika G, Arranz-Marquez E, Garcia-Gonzalez M, Hernández-Verdejo JL, Teus MA
Eur J Ophthalmol 2022 May;32(3):1441-1447. Epub 2021 Jul 27 doi: 10.1177/11206721211035633. PMID: 34313139
Difficulties with differentiating botulinum toxin treatment effects in essential blepharospasm.
Wabbels B, Jost WH, Roggenkämper P
J Neural Transm (Vienna) 2011 Jun;118(6):925-43. Epub 2011 Jan 9 doi: 10.1007/s00702-010-0546-9. PMID: 21221669Free PMC Article
Excessive blinking in childhood: a prospective evaluation of 99 children.
Coats DK, Paysse EA, Kim DS
Ophthalmology 2001 Sep;108(9):1556-61. doi: 10.1016/s0161-6420(01)00644-3. PMID: 11535449
Functional blinking in childhood.
Vrabec TR, Levin AV, Nelson LB
Pediatrics 1989 Jun;83(6):967-70. PMID: 2726353

Diagnosis

Pretarsal blepharospasm: Clinical and electromyographic characteristics.
Grandas F, Traba A, Perez-Sanchez JR, Esteban A
Clin Neurophysiol 2020 Jul;131(7):1678-1685. Epub 2020 Apr 2 doi: 10.1016/j.clinph.2020.03.016. PMID: 32280019
Episodic Excessive Blinking in Children.
Mali YP, Simon JW, Chaudhri I, Zobal-Ratner J, Barry GP
J Pediatr Ophthalmol Strabismus 2016 Jan-Feb;53(1):22-4. doi: 10.3928/01913913-20150929-18. PMID: 26835998
Excessive blinking and ataxia in a child with occult neuroblastoma and voltage-gated potassium channel antibodies.
Allen NM, McKeon A, O'Rourke DJ, O'Meara A, King MD
Pediatrics 2012 May;129(5):e1348-52. Epub 2012 Apr 23 doi: 10.1542/peds.2011-2690. PMID: 22529275
Difficulties with differentiating botulinum toxin treatment effects in essential blepharospasm.
Wabbels B, Jost WH, Roggenkämper P
J Neural Transm (Vienna) 2011 Jun;118(6):925-43. Epub 2011 Jan 9 doi: 10.1007/s00702-010-0546-9. PMID: 21221669Free PMC Article
Excessive blinking in childhood: a prospective evaluation of 99 children.
Coats DK, Paysse EA, Kim DS
Ophthalmology 2001 Sep;108(9):1556-61. doi: 10.1016/s0161-6420(01)00644-3. PMID: 11535449

Therapy

Impact of femtosecond laser-assisted in situ keratomileusis on retinal ganglion cell function.
Lauzirika G, Arranz-Marquez E, Garcia-Gonzalez M, Hernández-Verdejo JL, Teus MA
Eur J Ophthalmol 2022 May;32(3):1441-1447. Epub 2021 Jul 27 doi: 10.1177/11206721211035633. PMID: 34313139
Long-term treatment of blepharospasm with botulinum toxin A: a service-based study over a 16-year follow-up in southern China.
Fang XB, Xie MS, Song ZB, Zhong ZG, Wang Y, Ou ZL, Dang C, Li L, Zhang WX
Neurol Sci 2020 Mar;41(3):645-652. Epub 2019 Nov 19 doi: 10.1007/s10072-019-04123-8. PMID: 31745757
Difficulties with differentiating botulinum toxin treatment effects in essential blepharospasm.
Wabbels B, Jost WH, Roggenkämper P
J Neural Transm (Vienna) 2011 Jun;118(6):925-43. Epub 2011 Jan 9 doi: 10.1007/s00702-010-0546-9. PMID: 21221669Free PMC Article
Enhanced long-term potentiation-like plasticity of the trigeminal blink reflex circuit in blepharospasm.
Quartarone A, Sant'Angelo A, Battaglia F, Bagnato S, Rizzo V, Morgante F, Rothwell JC, Siebner HR, Girlanda P
J Neurosci 2006 Jan 11;26(2):716-21. doi: 10.1523/JNEUROSCI.3948-05.2006. PMID: 16407569Free PMC Article
The frequency of ocular symptoms during spectacle and daily soft and rigid contact lens wear.
Vajdic C, Holden BA, Sweeney DF, Cornish RM
Optom Vis Sci 1999 Oct;76(10):705-11. doi: 10.1097/00006324-199910000-00022. PMID: 10524786

Prognosis

Pupillometric and blink measures of diverse task loads: Implications for working memory models.
Chen S, Epps J, Paas F
Br J Educ Psychol 2023 Aug;93 Suppl 2:318-338. Epub 2022 Dec 26 doi: 10.1111/bjep.12577. PMID: 36572995
Long-term treatment of blepharospasm with botulinum toxin A: a service-based study over a 16-year follow-up in southern China.
Fang XB, Xie MS, Song ZB, Zhong ZG, Wang Y, Ou ZL, Dang C, Li L, Zhang WX
Neurol Sci 2020 Mar;41(3):645-652. Epub 2019 Nov 19 doi: 10.1007/s10072-019-04123-8. PMID: 31745757
Episodic Excessive Blinking in Children.
Mali YP, Simon JW, Chaudhri I, Zobal-Ratner J, Barry GP
J Pediatr Ophthalmol Strabismus 2016 Jan-Feb;53(1):22-4. doi: 10.3928/01913913-20150929-18. PMID: 26835998
The frequency of ocular symptoms during spectacle and daily soft and rigid contact lens wear.
Vajdic C, Holden BA, Sweeney DF, Cornish RM
Optom Vis Sci 1999 Oct;76(10):705-11. doi: 10.1097/00006324-199910000-00022. PMID: 10524786
Functional blinking in childhood.
Vrabec TR, Levin AV, Nelson LB
Pediatrics 1989 Jun;83(6):967-70. PMID: 2726353

Clinical prediction guides

Divergence excess and basic exotropia types of intermittent exotropia: a major review. Part 1: prevalence, classification, risk factors, natural history and clinical characteristics.
Ma MM, Scheiman M
Strabismus 2023 Jun;31(2):97-128. Epub 2023 Jul 25 doi: 10.1080/09273972.2023.2227681. PMID: 37489263
Pupillometric and blink measures of diverse task loads: Implications for working memory models.
Chen S, Epps J, Paas F
Br J Educ Psychol 2023 Aug;93 Suppl 2:318-338. Epub 2022 Dec 26 doi: 10.1111/bjep.12577. PMID: 36572995
Impact of femtosecond laser-assisted in situ keratomileusis on retinal ganglion cell function.
Lauzirika G, Arranz-Marquez E, Garcia-Gonzalez M, Hernández-Verdejo JL, Teus MA
Eur J Ophthalmol 2022 May;32(3):1441-1447. Epub 2021 Jul 27 doi: 10.1177/11206721211035633. PMID: 34313139
Long-term treatment of blepharospasm with botulinum toxin A: a service-based study over a 16-year follow-up in southern China.
Fang XB, Xie MS, Song ZB, Zhong ZG, Wang Y, Ou ZL, Dang C, Li L, Zhang WX
Neurol Sci 2020 Mar;41(3):645-652. Epub 2019 Nov 19 doi: 10.1007/s10072-019-04123-8. PMID: 31745757
Blepharospasm: an uncommon adverse effect caused by long-term administration of olanzapine.
Arora T, Maharshi V, Rehan HS, Nagar P
J Basic Clin Physiol Pharmacol 2017 Jan 1;28(1):85-87. doi: 10.1515/jbcpp-2016-0037. PMID: 27658142

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