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Post poliomyelitis syndrome

MedGen UID:
36363
Concept ID:
C0080040
Disease or Syndrome
Synonyms: Polio late effects; Post Polio syndrome; Post-polio muscular atrophy; Post-polio sequelae; Post-poliomyelitic syndrome; Postpoliomyelitis syndrome
SNOMED CT: Post-polio progressive muscular atrophy (31097004); Progressive muscular atrophy following poliomyelitis (31097004); Post poliomyelitis syndrome (31097004); Postpolio syndrome (31097004); Postpolio muscular atrophy (31097004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0017416
Orphanet: ORPHA2942

Definition

Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis (see this term), 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPost poliomyelitis syndrome

Professional guidelines

PubMed

Ramaraj R
Br J Hosp Med (Lond) 2007 Dec;68(12):648-50. doi: 10.12968/hmed.2007.68.12.648. PMID: 18186398

Recent clinical studies

Etiology

Sherf RM, Cantrell D, Or K, Marcus E, Shapira A, Benbassat C, Ish-Shalom S, Koren R
Endocr Pract 2020 Nov;26(11):1277-1285. doi: 10.4158/EP-2020-0102. PMID: 33471657
Pereira RD, Silva TM, Quadros AA, Orsini M, Schmidt B, Silva HC, Oliveira AS
Arq Neuropsiquiatr 2017 Mar;75(3):147-152. doi: 10.1590/0004-282X20170013. PMID: 28355321
Bickerstaffe A, Beelen A, Zwarts MJ, Nollet F, van Dijk JP
Muscle Nerve 2015 Jan;51(1):24-9. doi: 10.1002/mus.24272. PMID: 24777666
Lira CA, Minozzo FC, Sousa BS, Vancini RL, Andrade Mdos S, Quadros AA, Oliveira AS, da Silva AC
J Bras Pneumol 2013 Jun-Aug;39(4):455-60. doi: 10.1590/S1806-37132013000400009. PMID: 24068267Free PMC Article
Lin KH, Lim YW
Ann Acad Med Singap 2005 Aug;34(7):447-9. PMID: 16123820

Diagnosis

Abrar A, Ahmad A
J Pak Med Assoc 2015 Mar;65(3):327-9. PMID: 25933575
Quadros AA, Conde MT, Marin LF, Silva HC, Silva TM, Paula MB, Pereira RD, Ramos PE, Abe G, Oliveira AS
Arq Neuropsiquiatr 2012 Aug;70(8):571-3. doi: 10.1590/s0004-282x2012000800002. PMID: 22899025
Ramaraj R
Br J Hosp Med (Lond) 2007 Dec;68(12):648-50. doi: 10.12968/hmed.2007.68.12.648. PMID: 18186398
Neves MA, Mello MP, Santos VV, Nascimento OJ, Antonioli Rde S, Freitas GR, Freitas MR
Arq Neuropsiquiatr 2007 Jun;65(2B):528-31. doi: 10.1590/s0004-282x2007000300033. PMID: 17665030
Trojan DA, Cashman NR
Muscle Nerve 2005 Jan;31(1):6-19. doi: 10.1002/mus.20259. PMID: 15599928

Therapy

Da Silva CP Pt DSc Ncs, Zuckerman B Dpt, Olkin R PhD
Physiother Theory Pract 2017 May;33(5):370-375. Epub 2017 Apr 11 doi: 10.1080/09593985.2017.1307889. PMID: 28398102
van Tilburg CW
Am J Case Rep 2016 Dec 16;17:957-962. doi: 10.12659/ajcr.901157. PMID: 27980323Free PMC Article
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W
Complement Ther Med 2015 Dec;23(6):789-93. Epub 2015 Sep 9 doi: 10.1016/j.ctim.2015.09.002. PMID: 26645517
Dinsmore S, Dambrosia J, Dalakas MC
Ann N Y Acad Sci 1995 May 25;753:303-13. doi: 10.1111/j.1749-6632.1995.tb27556.x. PMID: 7611639
Trojan DA, Cashman NR
Ann N Y Acad Sci 1995 May 25;753:285-95. doi: 10.1111/j.1749-6632.1995.tb27554.x. PMID: 7611637

Prognosis

Agircan D, Ethemoglu O, Gesoglu-Demir T
Ideggyogy Sz 2022 May 30;75(5-06):207-210. doi: 10.18071/isz.75.0207. PMID: 35819339
Da Silva CP Pt DSc Ncs, Zuckerman B Dpt, Olkin R PhD
Physiother Theory Pract 2017 May;33(5):370-375. Epub 2017 Apr 11 doi: 10.1080/09593985.2017.1307889. PMID: 28398102
Trojan DA, Arnold DL, Shapiro S, Bar-Or A, Robinson A, Le Cruguel JP, Narayanan S, Tartaglia MC, Caramanos Z, Da Costa D
PM R 2009 May;1(5):442-9. doi: 10.1016/j.pmrj.2009.03.003. PMID: 19627931
Lin KH, Lim YW
Ann Acad Med Singap 2005 Aug;34(7):447-9. PMID: 16123820
Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM
Arch Phys Med Rehabil 1994 Jul;75(7):770-7. PMID: 8024423

Clinical prediction guides

Agircan D, Ethemoglu O, Gesoglu-Demir T
Ideggyogy Sz 2022 May 30;75(5-06):207-210. doi: 10.18071/isz.75.0207. PMID: 35819339
Sherf RM, Cantrell D, Or K, Marcus E, Shapira A, Benbassat C, Ish-Shalom S, Koren R
Endocr Pract 2020 Nov;26(11):1277-1285. doi: 10.4158/EP-2020-0102. PMID: 33471657
Lira CA, Minozzo FC, Sousa BS, Vancini RL, Andrade Mdos S, Quadros AA, Oliveira AS, da Silva AC
J Bras Pneumol 2013 Jun-Aug;39(4):455-60. doi: 10.1590/S1806-37132013000400009. PMID: 24068267Free PMC Article
Fordyce CB, Gagne D, Jalili F, Alatab S, Arnold DL, Da Costa D, Sawoszczuk S, Bodner C, Shapiro S, Collet JP, Robinson A, Le Cruguel JP, Lapierre Y, Bar-Or A, Trojan DA
J Neurol Sci 2008 Aug 15;271(1-2):80-6. Epub 2008 May 12 doi: 10.1016/j.jns.2008.03.015. PMID: 18474371
Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM
Arch Phys Med Rehabil 1994 Jul;75(7):770-7. PMID: 8024423

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