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microgyria

MedGen UID:
386642
Concept ID:
C2362742
Congenital Abnormality
Synonym: Microgyria
SNOMED CT: Microgyria (4945003)

Definition

A congenital abnormality characterized by the presence of abnormally small convolutions in the brain. It results in mental retardation. [from NCI]

Term Hierarchy

Recent clinical studies

Etiology

Hill C, Noureldein M, Karkhanis P, Kinning E, Vijay S, Gowda H
Am J Med Genet A 2023 Mar;191(3):859-863. Epub 2022 Dec 20 doi: 10.1002/ajmg.a.63083. PMID: 36538928
Chandra SP, Kurwale NS, Chibber SS, Banerji J, Dwivedi R, Garg A, Bal C, Tripathi M, Sarkar C, Tripathi M
Neurosurgery 2016 May;78(5):743-51. doi: 10.1227/NEU.0000000000001060. PMID: 26474092
Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Barkovich AJ, Peck WW
AJNR Am J Neuroradiol 1997 Jun-Jul;18(6):1163-70. PMID: 9194444Free PMC Article
Guerrini R, Dravet C, Raybaud C, Roger J, Bureau M, Battaglia A, Livet MO, Gambarelli D, Robain O
Dev Med Child Neurol 1992 Aug;34(8):706-18. doi: 10.1111/j.1469-8749.1992.tb11506.x. PMID: 1644233

Diagnosis

Tange Y, Aoki A, Mori K, Niijima S, Maeda M
Neurol Med Chir (Tokyo) 2000 Oct;40(10):536-42. doi: 10.2176/nmc.40.536. PMID: 11098642
Hablitz JJ, DeFazio T
Epilepsy Res 1998 Sep;32(1-2):75-82. doi: 10.1016/s0920-1211(98)00041-2. PMID: 9761310
Barkovich AJ, Peck WW
AJNR Am J Neuroradiol 1997 Jun-Jul;18(6):1163-70. PMID: 9194444Free PMC Article
Cramer SC, Schaefer PW, Krishnamoorthy KS
J Child Neurol 1996 Nov;11(6):494-7. doi: 10.1177/088307389601100619. PMID: 9120232
Curatolo P, Pruna D, Cusmai R, Feliciani M
Brain Dev 1989;11(4):257-9. doi: 10.1016/s0387-7604(89)80046-4. PMID: 2774095

Therapy

Stöllberger C, Finsterer J
Neurol Neurochir Pol 2017 Mar-Apr;51(2):194-196. Epub 2017 Feb 3 doi: 10.1016/j.pjnns.2017.01.010. PMID: 28215696
Threlkeld SW, Hill CA, Rosen GD, Fitch RH
Int J Dev Neurosci 2009 Jun;27(4):321-8. Epub 2009 Apr 1 doi: 10.1016/j.ijdevneu.2009.03.007. PMID: 19460626Free PMC Article
Cui C, Sakata-Haga H, Ohta K, Nishida M, Yashiki M, Sawada K, Fukui Y
Congenit Anom (Kyoto) 2006 Dec;46(4):180-7. doi: 10.1111/j.1741-4520.2006.00126.x. PMID: 17096818

Prognosis

Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Gérard-Blanluet M, Sheen V, Machinis K, Neal J, Apse K, Danan C, Sinico M, Brugières P, Mage K, Ratsimbazafy L, Elbez A, Janaud JC, Amselem S, Walsh C, Encha-Razavi F
Am J Med Genet A 2006 May 15;140(10):1041-6. doi: 10.1002/ajmg.a.31197. PMID: 16596669
Güngör N, Coşkun T, Akçören Z, Cağlar M
Turk J Pediatr 1994 Apr-Jun;36(2):145-52. PMID: 8016916

Clinical prediction guides

Lanska DJ, Leblanc R
J Hist Neurosci 2024 Jul-Sep;33(3):275-297. Epub 2024 Mar 8 doi: 10.1080/0964704X.2024.2319079. PMID: 38457353
Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Jacobs KM, Kharazia VN, Prince DA
Epilepsy Res 1999 Sep;36(2-3):165-88. doi: 10.1016/s0920-1211(99)00050-9. PMID: 10515164
Giannetti S, Gaglini P, Granato A, Di Rocco C
Childs Nerv Syst 1999 Sep;15(9):444-8; discussion 449-50. doi: 10.1007/s003810050435. PMID: 10502002
de León GA
Acta Neuropathol 1972;20(4):278-87. doi: 10.1007/BF00691746. PMID: 5047106

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