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Slit ventricle syndrome

MedGen UID:
389221
•Concept ID:
C2316166
•
Disease or Syndrome
Synonyms: Slit Ventricle Syndrome; Slit Ventricle Syndromes; Syndrome, Slit Ventricle; Syndromes, Slit Ventricle
SNOMED CT: Slit ventricle syndrome (431468008)

Definition

An intermittent and self-limiting headache disorder in individuals with CEREBROSPINAL FLUID SHUNTS emplaced for the treatment of HYDROCEPHALUS. The symptoms of headache, vomiting, and cranial neuropathies are associated with intermittent obstruction of the shunt. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSlit ventricle syndrome

Professional guidelines

PubMed

Short-term dexamethasone treatment for symptomatic slit ventricle syndrome.
Steinbok P
Childs Nerv Syst 2005 Nov;21(11):985. doi: 10.1007/s00381-004-1133-x. PMID: 15933886
The problematic slit ventricle syndrome. A review of the literature and proposed algorithm for treatment.
Olson S
Pediatr Neurosurg 2004 Nov-Dec;40(6):264-9. doi: 10.1159/000083738. PMID: 15821356
Diagnosis and treatment of the slit ventricle syndrome.
Walker ML, Fried A, Petronio J
Neurosurg Clin N Am 1993 Oct;4(4):707-14. PMID: 8241791

Recent clinical studies

Etiology

Positional shunt assist for slit ventricle syndrome.
Azolai L, Constantini S, Constantini L, Roth J
Childs Nerv Syst 2024 Jan;40(1):109-114. Epub 2023 Sep 11 doi: 10.1007/s00381-023-06145-2. PMID: 37695368
Kyphectomy and Pedicular Screw Fixation with Posterior-Only Approach in Pediatric Patients with Myelomeningocele.
Kaplan SÇ, Ekşi MŞ, Bayri Y, Toktaş ZO, Konya D
Pediatr Neurosurg 2015;50(3):133-44. Epub 2015 Jun 6 doi: 10.1159/000430467. PMID: 26067202
ETV as a last resort.
Mandiwanza T, Zakaria Z, Khalil A, Crimmins D, Caird J
Childs Nerv Syst 2014 May;30(5):859-66. Epub 2013 Nov 30 doi: 10.1007/s00381-013-2330-2. PMID: 24292271
The problematic slit ventricle syndrome. A review of the literature and proposed algorithm for treatment.
Olson S
Pediatr Neurosurg 2004 Nov-Dec;40(6):264-9. doi: 10.1159/000083738. PMID: 15821356
Experience with antisyphon devices: successes and complications.
Jaskolska E, MacKinnon AE
Z Kinderchir 1988 Dec;43 Suppl 2:22-3. doi: 10.1055/s-2008-1044149. PMID: 3213246

Diagnosis

Slit Ventricle Syndrome.
Yan X, Zheng J, Tao X, Ma Y, Qin S
J Craniofac Surg 2023 Sep 1;34(6):e566-e568. Epub 2023 May 25 doi: 10.1097/SCS.0000000000009400. PMID: 37226307
Management of Slit Ventricle Syndrome: A Single-Center Case Series of 32 Surgically Treated Patients.
Auricchio AM, Bohnen A, Nichelatti M, Cenzato M, Talamonti G
World Neurosurg 2022 Feb;158:e352-e361. Epub 2021 Nov 6 doi: 10.1016/j.wneu.2021.10.183. PMID: 34749014
Craniocerebral disproportion: a topical review and proposal toward a new definition, diagnosis, and treatment protocol.
Sandler AL, Goodrich JT, Daniels LB 3rd, Biswas A, Abbott R
Childs Nerv Syst 2013 Nov;29(11):1997-2010. Epub 2013 Aug 24 doi: 10.1007/s00381-013-2257-7. PMID: 23974969
Lumbar peritoneal shunt.
Yadav YR, Parihar V, Sinha M
Neurol India 2010 Mar-Apr;58(2):179-84. doi: 10.4103/0028-3886.63778. PMID: 20508332
The slit ventricle syndrome.
Bruce DA, Weprin B
Neurosurg Clin N Am 2001 Oct;12(4):709-17, viii. PMID: 11524292

Therapy

Slit Ventricle Syndrome.
Yan X, Zheng J, Tao X, Ma Y, Qin S
J Craniofac Surg 2023 Sep 1;34(6):e566-e568. Epub 2023 May 25 doi: 10.1097/SCS.0000000000009400. PMID: 37226307
Management of Slit Ventricle Syndrome: A Single-Center Case Series of 32 Surgically Treated Patients.
Auricchio AM, Bohnen A, Nichelatti M, Cenzato M, Talamonti G
World Neurosurg 2022 Feb;158:e352-e361. Epub 2021 Nov 6 doi: 10.1016/j.wneu.2021.10.183. PMID: 34749014
Shunt overdrainage syndrome: review of the literature.
Ros B, Iglesias S, Martín Á, Carrasco A, Ibáñez G, Arráez MA
Neurosurg Rev 2018 Oct;41(4):969-981. Epub 2017 Mar 29 doi: 10.1007/s10143-017-0849-5. PMID: 28352945
Craniocerebral disproportion: a topical review and proposal toward a new definition, diagnosis, and treatment protocol.
Sandler AL, Goodrich JT, Daniels LB 3rd, Biswas A, Abbott R
Childs Nerv Syst 2013 Nov;29(11):1997-2010. Epub 2013 Aug 24 doi: 10.1007/s00381-013-2257-7. PMID: 23974969
The slit ventricle syndrome: advances based on technology and understanding.
Rekate HL
Pediatr Neurosurg 2004 Nov-Dec;40(6):259-63. doi: 10.1159/000083737. PMID: 15821355

Prognosis

Management of Slit Ventricle Syndrome: A Single-Center Case Series of 32 Surgically Treated Patients.
Auricchio AM, Bohnen A, Nichelatti M, Cenzato M, Talamonti G
World Neurosurg 2022 Feb;158:e352-e361. Epub 2021 Nov 6 doi: 10.1016/j.wneu.2021.10.183. PMID: 34749014
The use of noninvasive electromagnetic neuronavigation for slit ventricle syndrome and complex hydrocephalus in a pediatric population.
Clark S, Sangra M, Hayhurst C, Kandasamy J, Jenkinson M, Lee M, Mallucci C
J Neurosurg Pediatr 2008 Dec;2(6):430-4. doi: 10.3171/PED.2008.2.12.430. PMID: 19035692
The slit ventricle syndrome.
Bruce DA, Weprin B
Neurosurg Clin N Am 2001 Oct;12(4):709-17, viii. PMID: 11524292
Long-term results after ventriculo-atrial shunting in children.
Vernet O, Campiche R, de Tribolet N
Childs Nerv Syst 1995 Mar;11(3):176-9. doi: 10.1007/BF00570261. PMID: 7773980
Experience with antisyphon devices: successes and complications.
Jaskolska E, MacKinnon AE
Z Kinderchir 1988 Dec;43 Suppl 2:22-3. doi: 10.1055/s-2008-1044149. PMID: 3213246

Clinical prediction guides

Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis.
Khan M, Craven CL, Tahir MZ
Pediatr Neurosurg 2023;58(6):420-428. Epub 2023 Oct 17 doi: 10.1159/000534611. PMID: 37848014
Cranial expansion and aqueductoplasty for combined isolated fourth ventricle and slit-ventricle syndrome: a surgical alternative.
Tirado-Caballero J, Rivero-Garvia M, Moreno-Madueño G, Gómez-González E, Márquez-Rivas J
Childs Nerv Syst 2021 Mar;37(3):885-894. Epub 2020 Oct 25 doi: 10.1007/s00381-020-04939-2. PMID: 33099694
Development of brain ventricular system.
Korzh V
Cell Mol Life Sci 2018 Feb;75(3):375-383. Epub 2017 Aug 5 doi: 10.1007/s00018-017-2605-y. PMID: 28780589Free PMC Article
Shunt Testing In Vivo: Observational Study of Problems with Ventricular Catheter.
Czosnyka ZH, Sinha R, Morgan JA, Wawrzynski JR, Price SJ, Garnett M, Pickard JD, Czosnyka M
Acta Neurochir Suppl 2016;122:353-6. doi: 10.1007/978-3-319-22533-3_69. PMID: 27165935
The slit ventricle syndrome: advances based on technology and understanding.
Rekate HL
Pediatr Neurosurg 2004 Nov-Dec;40(6):259-63. doi: 10.1159/000083737. PMID: 15821355

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