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Nevoid Melanoma

MedGen UID:
406940
•Concept ID:
C1882081
•
Neoplastic Process
Synonym: Nevoid melanoma
SNOMED CT: Nevoid melanoma (1285320000); Nevoid melanoma (1285321001)

Definition

A rare variant of cutaneous melanoma occurring mostly in adults in their fifth decade. Morphologically it resembles an ordinary compound or dermal nevus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNevoid Melanoma

Professional guidelines

PubMed

Diagnosis and treatment of basal cell carcinoma: European consensus-based interdisciplinary guidelines.
Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, Bataille V, Marmol VD, Dummer R, Harwood CA, Hauschild A, Höller C, Haedersdal M, Malvehy J, Middleton MR, Morton CA, Nagore E, Stratigos AJ, Szeimies RM, Tagliaferri L, Trakatelli M, Zalaudek I, Eggermont A, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2019 Sep;118:10-34. Epub 2019 Jul 6 doi: 10.1016/j.ejca.2019.06.003. PMID: 31288208
Diagnosis and Management of Hereditary Basal Cell Skin Cancer.
Shanley S, McCormack C
Recent Results Cancer Res 2016;205:191-212. doi: 10.1007/978-3-319-29998-3_11. PMID: 27075355
Diagnosis and management of premalignant melanocytic proliferations.
Sagebiel RW
Pathology 1985 Apr;17(2):285-90. doi: 10.3109/00313028509063769. PMID: 4047733

Recent clinical studies

Etiology

Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546
Mitotically Active Nevus and Nevoid Melanoma: A Clinicopathological and Molecular Study.
Mesbah Ardakani N, Singh S, Thomas C, Van Vliet C, Harvey NT, Calonje JE, Wood BA
Am J Dermatopathol 2021 Mar 1;43(3):182-190. doi: 10.1097/DAD.0000000000001721. PMID: 32649342
The limitations of dermoscopy: false-positive and false-negative tumours.
Papageorgiou V, Apalla Z, Sotiriou E, Papageorgiou C, Lazaridou E, Vakirlis S, Ioannides D, Lallas A
J Eur Acad Dermatol Venereol 2018 Jun;32(6):879-888. Epub 2018 Jan 24 doi: 10.1111/jdv.14782. PMID: 29314288
Nevoid melanoma: A study of 43 cases with emphasis on growth pattern.
Idriss MH, Rizwan L, Sferuzza A, Wasserman E, Kazlouskaya V, Elston DM
J Am Acad Dermatol 2015 Nov;73(5):836-42. Epub 2015 Aug 20 doi: 10.1016/j.jaad.2015.07.003. PMID: 26299955
Melanocytic nevi simulant of melanoma with medicolegal relevance.
Massi G
Virchows Arch 2007 Sep;451(3):623-47. Epub 2007 Jul 26 doi: 10.1007/s00428-007-0459-7. PMID: 17653760

Diagnosis

Immunohistochemistry in melanocytic lesions: Updates with a practical review for pathologists.
Saleem A, Narala S, Raghavan SS
Semin Diagn Pathol 2022 Jul;39(4):239-247. Epub 2022 Jan 1 doi: 10.1053/j.semdp.2021.12.003. PMID: 35016807
Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546
Dermatoscopy of melanoma according to type, anatomic site and stage.
Lallas A, Paschou E, Manoli SM, Papageorgiou C, Spyridis I, Liopyris K, Bobos M, Moutsoudis A, Lazaridou E, Apalla Z
Ital J Dermatol Venerol 2021 Jun;156(3):274-288. Epub 2020 Dec 14 doi: 10.23736/S2784-8671.20.06784-X. PMID: 33314891
BRCA1-associated protein (BAP1)-inactivated melanocytic tumors.
Zhang AJ, Rush PS, Tsao H, Duncan LM
J Cutan Pathol 2019 Dec;46(12):965-972. Epub 2019 Jul 11 doi: 10.1111/cup.13530. PMID: 31233225
Nevoid melanoma.
Diwan AH, Lazar AJ
Clin Lab Med 2011 Jun;31(2):243-53. doi: 10.1016/j.cll.2011.03.002. PMID: 21549238

Therapy

Nevoid melanoma and eruptive nevi from erlotinib.
Seidman JS, Eichenfield DZ, Orme CM
Dermatol Online J 2020 Jun 15;26(6) PMID: 32815691

Prognosis

Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546
Nevoid melanoma.
Diwan AH, Lazar AJ
Clin Lab Med 2011 Jun;31(2):243-53. doi: 10.1016/j.cll.2011.03.002. PMID: 21549238
Unusual variants of malignant melanoma.
Barnhill RL, Gupta K
Clin Dermatol 2009 Nov-Dec;27(6):564-87. doi: 10.1016/j.clindermatol.2008.09.015. PMID: 19880044
Epigenetic marks in melanoma.
Richards HW, Medrano EE
Pigment Cell Melanoma Res 2009 Feb;22(1):14-29. Epub 2008 Nov 27 doi: 10.1111/j.1755-148X.2008.00534.x. PMID: 19040501
Morphological analysis of nevoid melanoma: a study of 20 cases with a review of the literature.
Zembowicz A, McCusker M, Chiarelli C, Dei Tos AP, Granter SR, Calonje E, McKee PH
Am J Dermatopathol 2001 Jun;23(3):167-75. doi: 10.1097/00000372-200106000-00001. PMID: 11391094

Clinical prediction guides

Refining the application of PRAME-a useful marker in high CSD and acral melanoma subtypes.
Wakefield C, O'Keefe L, Heffron CCBB
Virchows Arch 2023 Dec;483(6):847-854. Epub 2023 Sep 19 doi: 10.1007/s00428-023-03648-w. PMID: 37723345
Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546
Nevoid melanoma and eruptive nevi from erlotinib.
Seidman JS, Eichenfield DZ, Orme CM
Dermatol Online J 2020 Jun 15;26(6) PMID: 32815691
Nevoid iris melanoma, case report.
Saldaña-Garrido JD, Martínez-Hergueta MC, Martínez-Rubio MM
Arch Soc Esp Oftalmol 2017 Jul;92(7):347-350. Epub 2016 Jun 1 doi: 10.1016/j.oftal.2016.04.005. PMID: 27262610
Fluorescence in situ hybridization for distinguishing nevoid melanomas from mitotically active nevi.
Gerami P, Wass A, Mafee M, Fang Y, Pulitzer MP, Busam KJ
Am J Surg Pathol 2009 Dec;33(12):1783-8. doi: 10.1097/PAS.0b013e3181ba6db6. PMID: 19809275

Recent systematic reviews

Clinical and Dermoscopic Features Associated With Difficult-to-Recognize Variants of Cutaneous Melanoma: A Systematic Review.
Pampena R, Lai M, Lombardi M, Mirra M, Raucci M, Lallas A, Apalla Z, Argenziano G, Pellacani G, Longo C
JAMA Dermatol 2020 Apr 1;156(4):430-439. doi: 10.1001/jamadermatol.2019.4912. PMID: 32101255

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