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Infection by Dracunculus medinensis(GWD)

MedGen UID:
41653
Concept ID:
C0013100
Disease or Syndrome
Synonyms: Dracunculiasis; Guinea worm disease; Guinea worm infection; GWD; Parasitic infection caused by Dracunculus medinensis
SNOMED CT: Infection by Dracunculus medinensis (396334002); Dracontiasis - guinea-worm (396334002); Dracontiasis (396334002); Dracunculosis (396334002); Guinea-worm infection (396334002); Guinea worm disease (396334002); Dracunculiasis (396334002); Infection caused by Dracunculus medinensis (396334002)
 
Monarch Initiative: MONDO:0016472
Orphanet: ORPHA231

Definition

Dracunculiasis (Guinea worm disease) is a neglected tropical disease (NTD) characterized by a painful burning skin lesion from which the <i>Dracunculus medinensis</i> parasite emerges approximately 1 year after infection resulting from consumption of unsafe drinking water containing parasite-infected copepods (<i>Cyclops spp.</i>, microcrustacea also called water fleas). [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfection by Dracunculus medinensis
Follow this link to review classifications for Infection by Dracunculus medinensis in Orphanet.

Professional guidelines

PubMed

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Recent clinical studies

Etiology

Harada Y, Iwashita H, Moriyasu T, Nagi S, Saito N, Sugawara-Mikami M, Yoshioka K, Yotsu R; Japan NTD Study Group
PLoS Negl Trop Dis 2024 Jan;18(1):e0011854. Epub 2024 Jan 2 doi: 10.1371/journal.pntd.0011854. PMID: 38166156Free PMC Article
Mari L, Ciddio M, Casagrandi R, Perez-Saez J, Bertuzzo E, Rinaldo A, Sokolow SH, De Leo GA, Gatto M
J Theor Biol 2017 Nov 7;432:87-99. Epub 2017 Aug 17 doi: 10.1016/j.jtbi.2017.08.015. PMID: 28823529Free PMC Article
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Bhalla D, Dumas M, Preux PM
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Okwa OO
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Diagnosis

Molyneux DH, Eberhard ML, Cleaveland S, Addey R, Guiguemdé RT, Kumar A, Magnussen P, Breman JG
Lancet 2020 Dec 5;396(10265):1857-1860. doi: 10.1016/S0140-6736(20)32553-8. PMID: 33278938
Pichakacheri SK
Natl Med J India 2019 Jan-Feb;32(1):22-23. doi: 10.4103/0970-258X.272111. PMID: 31823935
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Korevaar DA, Visser BJ
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Grove DI
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Therapy

Chai JY, Jung BK, Hong SJ
Korean J Parasitol 2021 Jun;59(3):189-225. Epub 2021 Jun 21 doi: 10.3347/kjp.2021.59.3.189. PMID: 34218593Free PMC Article
Grove DI
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Prognosis

Molyneux DH, Eberhard ML, Cleaveland S, Addey R, Guiguemdé RT, Kumar A, Magnussen P, Breman JG
Lancet 2020 Dec 5;396(10265):1857-1860. doi: 10.1016/S0140-6736(20)32553-8. PMID: 33278938
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Clinical prediction guides

Eneanya OA, Delea MG, Cano J, Tchindebet PO, Richards RL, Zhao Y, Meftuh A, Unterwegner K, Guagliardo SAJ, Hopkins DR, Weiss A
Am J Trop Med Hyg 2024 Sep 3;111(3_Suppl):26-35. Epub 2024 Jul 9 doi: 10.4269/ajtmh.23-0681. PMID: 38981489Free PMC Article
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Recent systematic reviews

Lemma GW, Müller O, Reñosa MD, Lu G
Trop Med Int Health 2020 Dec;25(12):1432-1440. Epub 2020 Oct 8 doi: 10.1111/tmi.13492. PMID: 32946140
Kappagoda S, Ioannidis JP
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Supplemental Content

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