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Heart aneurysm

MedGen UID:
42360
•Concept ID:
C0018789
•
Disease or Syndrome
Synonyms: Aneurysm, Cardiac; Aneurysm, Heart; Aneurysms, Cardiac; Aneurysms, Heart; Cardiac Aneurysm; Cardiac Aneurysms; Heart Aneurysm; Heart Aneurysms
SNOMED CT: Aneurysm of heart (65340007); Cardiac aneurysm (65340007)
 
Monarch Initiative: MONDO:0006779

Definition

A localized bulging or dilatation in the muscle wall of a heart (myocardium), usually in the left ventricle. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are hematoma caused by myocardial rupture. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHeart aneurysm

Professional guidelines

PubMed

Treatment of ischaemic heart disease complications.
Moll JW
Cor Vasa 1984;26(5):376-83. PMID: 6509993
SYSTOLIC MURMUR DEVELOPING AFTER MYOCARDIAL ISCHEMIA OR INFARCTION: DIFFERENTIAL DIAGNOSIS.
HOLLOWAY DH Jr, WHALEN RE, MCINTOSH HD
JAMA 1965 Mar 15;191:888-92. doi: 10.1001/jama.1965.03080110012002. PMID: 14260219
Rupture of congenital aneurysm of sinus of Valsava into right ventricle. Its diagnosis and treatment.
CH'EN HC, T'AO SC, SHIH MH, WAN TH
Chin Med J 1962 Dec;81:784-91. PMID: 14019800

Recent clinical studies

Etiology

Left ventricular pseudo-pseudoaneurysm.
García-Lledó A, Moya Mur JL, García Segovia J
Rev Esp Cardiol (Engl Ed) 2015 Feb;68(2):147. Epub 2014 Jun 27 doi: 10.1016/j.rec.2014.02.027. PMID: 25623433
Left atrial dissection: an almost unknown entity.
Fukuhara S, Dimitrova KR, Geller CM, Hoffman DM, Tranbaugh RF
Interact Cardiovasc Thorac Surg 2015 Jan;20(1):96-100. Epub 2014 Sep 25 doi: 10.1093/icvts/ivu317. PMID: 25260895
Intracavernous carotid artery aneurysms.
Cakir E, Karaarslan G, Kuzeyli K, Usul H, Sayin OC, Birinci O, Baykal S
J Clin Neurosci 2004 Nov;11(8):859-62. doi: 10.1016/j.jocn.2003.11.017. PMID: 15519863
Left atrial aneurysm.
Morales JM, Patel SG, Jackson JH, Duff JA, Simpson JW
Ann Thorac Surg 2001 Feb;71(2):719-22. doi: 10.1016/s0003-4975(00)02244-x. PMID: 11235743
Transesophageal echocardiography in stroke.
Rodriguez C, Homma S, Di Tullio M
Cardiol Rev 2000 May-Jun;8(3):140-7. doi: 10.1097/00045415-200008030-00004. PMID: 11174887

Diagnosis

Not Your Common Electrocardiographic Findings.
Pan D, Chang Q, Liu R
Circulation 2020 Oct 13;142(15):1494-1496. Epub 2020 Oct 12 doi: 10.1161/CIRCULATIONAHA.120.049831. PMID: 33044860
Left atrial appendage aneurysm.
Jiang B, Wang X, Liu F, Song L
Interact Cardiovasc Thorac Surg 2020 Mar 1;30(3):495-496. doi: 10.1093/icvts/ivz283. PMID: 31773142
A Third Ventricle?
Ward CC, Schmidt GA
Ann Am Thorac Soc 2019 May;16(5):631-635. doi: 10.1513/AnnalsATS.201811-808CC. PMID: 31042095
Sub-mitral aneurysm.
Guimfacq V, Kemdem A, Vandenbossche JL
Eur Heart J 2009 Jan;30(1):43. Epub 2008 Jul 4 doi: 10.1093/eurheartj/ehn322. PMID: 18603622
Ventricular aneurysmectomy.
Loop FD
Surg Clin North Am 1971 Oct;51(5):1071-9. doi: 10.1016/s0039-6109(16)39533-0. PMID: 4938643

Therapy

The Worth of a Miracle.
JAMA 2021 Feb 23;325(8):793. doi: 10.1001/jama.2020.17810. PMID: 33620392
Unusual Submitral Aneurysms.
Faria DC, Ribeiro R, Sousa-Uva M, Freitas A, Ferreira A, Soares AO, Borges Santos M, Gouveia R, Ramos S, Delgado Alves J, Augusto JB
Circ Cardiovasc Imaging 2020 Oct;13(10):e010466. Epub 2020 Sep 22 doi: 10.1161/CIRCIMAGING.120.010466. PMID: 32957799
Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke.
Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L, Arquizan C, Béjot Y, Vuillier F, Detante O, Guidoux C, Canaple S, Vaduva C, Dequatre-Ponchelle N, Sibon I, Garnier P, Ferrier A, Timsit S, Robinet-Borgomano E, Sablot D, Lacour JC, Zuber M, Favrole P, Pinel JF, Apoil M, Reiner P, Lefebvre C, Guérin P, Piot C, Rossi R, Dubois-Randé JL, Eicher JC, Meneveau N, Lusson JR, Bertrand B, Schleich JM, Godart F, Thambo JB, Leborgne L, Michel P, Pierard L, Turc G, Barthelet M, Charles-Nelson A, Weimar C, Moulin T, Juliard JM, Chatellier G; CLOSE Investigators
N Engl J Med 2017 Sep 14;377(11):1011-1021. doi: 10.1056/NEJMoa1705915. PMID: 28902593
Left atrial dissection.
Tsukui H, Iwasa S, Yamazaki K
Gen Thorac Cardiovasc Surg 2015 Aug;63(8):434-45. Epub 2015 May 24 doi: 10.1007/s11748-015-0562-7. PMID: 26003839
Antithrombotic therapy in valvular heart disease.
Salem DN, Daudelin HD, Levine HJ, Pauker SG, Eckman MH, Riff J
Chest 2001 Jan;119(1 Suppl):207S-219S. doi: 10.1378/chest.119.1_suppl.207s. PMID: 11157650

Prognosis

Hypertrophic Cardiomyopathy With Left Ventricular Apical Aneurysm: Implications for Risk Stratification and Management.
Rowin EJ, Maron BJ, Haas TS, Garberich RF, Wang W, Link MS, Maron MS
J Am Coll Cardiol 2017 Feb 21;69(7):761-773. doi: 10.1016/j.jacc.2016.11.063. PMID: 28209216
Left Atrial Appendage Aneurysm.
Hosseini S, Hashemi A, Saedi S, Jalili F, Maleki M, Jalalian R, Rezaei Y
Ann Thorac Surg 2016 Sep;102(3):e207-e209. doi: 10.1016/j.athoracsur.2016.02.012. PMID: 27549544
Left ventricular pseudo-pseudoaneurysm.
García-Lledó A, Moya Mur JL, García Segovia J
Rev Esp Cardiol (Engl Ed) 2015 Feb;68(2):147. Epub 2014 Jun 27 doi: 10.1016/j.rec.2014.02.027. PMID: 25623433
Left atrial dissection: an almost unknown entity.
Fukuhara S, Dimitrova KR, Geller CM, Hoffman DM, Tranbaugh RF
Interact Cardiovasc Thorac Surg 2015 Jan;20(1):96-100. Epub 2014 Sep 25 doi: 10.1093/icvts/ivu317. PMID: 25260895
Left ventricular pseudoaneurysm.
Frances C, Romero A, Grady D
J Am Coll Cardiol 1998 Sep;32(3):557-61. doi: 10.1016/s0735-1097(98)00290-3. PMID: 9741493

Clinical prediction guides

Congenital giant right atrial aneurysm.
Sepulveda S, Rosental C, Choe HJ, Cornelis J, Salgado G
Int J Cardiovasc Imaging 2024 Mar;40(3):687-691. Epub 2023 Dec 1 doi: 10.1007/s10554-023-03025-3. PMID: 38040948
Left atrial dissection.
Tsukui H, Iwasa S, Yamazaki K
Gen Thorac Cardiovasc Surg 2015 Aug;63(8):434-45. Epub 2015 May 24 doi: 10.1007/s11748-015-0562-7. PMID: 26003839
Characteristics and outcome of primary congenital left ventricular aneurysm and diverticulum: analysis of cases from the literature.
Ohlow MA, Brunelli M, Lauer B
Prenat Diagn 2014 Sep;34(9):893-9. Epub 2014 May 15 doi: 10.1002/pd.4389. PMID: 24752829
The fetal ductus arteriosus and its abnormalities--a review.
Weichert J, Hartge DR, Axt-Fliedner R
Congenit Heart Dis 2010 Sep-Oct;5(5):398-408. doi: 10.1111/j.1747-0803.2010.00424.x. PMID: 21087423
Periannular extension of infective endocarditis.
Kang N, Wan S, Ng CS, Underwood MJ
Ann Thorac Cardiovasc Surg 2009 Apr;15(2):74-81. PMID: 19471219

Recent systematic reviews

Right Ventricular Outflow Tract Obstruction by an Aneurysm of the Ventricular Membranous Septum: A Systematic Review of Case Reports.
Miyake T, Inoue T, Mushiake S
World J Pediatr Congenit Heart Surg 2024 May;15(3):380-388. Epub 2024 Jan 23 doi: 10.1177/21501351231215258. PMID: 38263669
Vascular aneurysms in Ehlers-Danlos syndrome subtypes: A systematic review.
Shabani M, Abdollahi A, Brar BK, MacCarrick GL, Ambale Venkatesh B, Lima JAC, Bodurtha JN
Clin Genet 2023 Mar;103(3):261-267. Epub 2022 Oct 24 doi: 10.1111/cge.14245. PMID: 36210598
Isolated Aneurysms of the Membranous Ventricular Septum Without Residual Shunts: Systematic Review and Description of 3 Cases in Adults.
Abdul Jabbar A, Mufti O, Mazur W, Quraishi MB, Srivastava BK, Tivakaran V
J Ultrasound Med 2017 May;36(5):869-878. Epub 2017 Feb 23 doi: 10.7863/ultra.16.02087. PMID: 28230264
Left atrial appendage aneurysm: a systematic review of 82 cases.
Aryal MR, Hakim FA, Ghimire S, Ghimire S, Giri S, Pandit A, Bhandari Y, Bhandari N, Pathak R, Karmacharya P, Pradhan R
Echocardiography 2014 Nov;31(10):1312-8. Epub 2014 Jun 28 doi: 10.1111/echo.12667. PMID: 24976376
Right atrial appendage aneurysm: a systematic review.
Aryal MR, Hakim FA, Giri S, Ghimire S, Pandit A, Bhandari Y, Acharya YP, Pradhan R
Echocardiography 2014 Apr;31(4):534-9. Epub 2014 Jan 22 doi: 10.1111/echo.12510. PMID: 24447323

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