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Yang deficiency

MedGen UID:
43139
•Concept ID:
C0085258
•
Pathologic Function
Synonyms: Deficiency, Yang; Hsu, Yang; Xu, Yang; Yang Deficiency; Yang Hsu; Yang Xu; Yangxu
SNOMED CT: Yang deficiency (370534002)

Definition

In the YIN-YANG system of philosophy and medicine, a lack of vital energy (called yangxu in Chinese). It manifests itself in various systemic and organic diseases. (The Pinyin Chinese-English Dictionary, 1979) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVYang deficiency

Professional guidelines

PubMed

Efficacy and safety of Linggui Zhugan decoction in the treatment of chronic heart failure with Yang deficiency: A protocol for systematic review and meta-analysis.
Li Y, Wu H, Zhang B, Xu X, Wang Y, Song Q
Medicine (Baltimore) 2021 May 21;100(20):e26012. doi: 10.1097/MD.0000000000026012. PMID: 34011101Free PMC Article
Diagnostic and Categorization Criteria for Palpitations Below the Heart in Traditional Chinese Medicine: A Delphi Consensus Study.
Song C, Ye X, Fu H, Lin L, Jin Y, Liu F, Zhu W
Altern Ther Health Med 2021 Sep;27(5):68-72. PMID: 33128537
Clinical trials of traditional Chinese medicine in the treatment of diabetic nephropathy--a systematic review based on a subgroup analysis.
Liu X, Liu L, Chen P, Zhou L, Zhang Y, Wu Y, Jiang L, Cheng D, Huang W, Yi D
J Ethnopharmacol 2014 Feb 3;151(2):810-9. Epub 2013 Dec 1 doi: 10.1016/j.jep.2013.11.028. PMID: 24296085

Recent clinical studies

Etiology

Dose-effect of long-snake-like moxibustion for chronic fatigue syndrome: a randomized controlled trial.
Luo H, Gong R, Zheng R, Tan J, Chen R, Wu J, Ma T
J Transl Med 2023 Jul 3;21(1):430. doi: 10.1186/s12967-023-04250-z. PMID: 37400824Free PMC Article
Efficacy and safety of Chinese herbal medicine Wen Xin granules for the treatment of unstable angina pectoris with Yang deficiency and blood stasis syndrome: study protocol for a randomized controlled trial.
Tian PP, Wu QJ, Li J, Chen HW, Wu J, Deng YW, Xie ZC, Zhao W, Tan YQ
Trials 2021 Nov 13;22(1):798. doi: 10.1186/s13063-021-05771-y. PMID: 34774099Free PMC Article
Efficacy and safety of Linggui Zhugan decoction in the treatment of chronic heart failure with Yang deficiency: A protocol for systematic review and meta-analysis.
Li Y, Wu H, Zhang B, Xu X, Wang Y, Song Q
Medicine (Baltimore) 2021 May 21;100(20):e26012. doi: 10.1097/MD.0000000000026012. PMID: 34011101Free PMC Article
The characteristics of intestinal flora of IBS-D with different syndromes.
Chao G, Zhang S
Immun Inflamm Dis 2020 Dec;8(4):615-628. Epub 2020 Sep 17 doi: 10.1002/iid3.348. PMID: 32940426Free PMC Article
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;2015(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906Free PMC Article

Diagnosis

End-to-End syndrome differentiation of Yin deficiency and Yang deficiency in traditional Chinese medicine.
Hu Q, Yu T, Li J, Yu Q, Zhu L, Gu Y
Comput Methods Programs Biomed 2019 Jun;174:9-15. Epub 2018 Oct 16 doi: 10.1016/j.cmpb.2018.10.011. PMID: 30376987
Integrative metabolic and microbial profiling on patients with Spleen-yang-deficiency syndrome.
Lin Z, Ye W, Zu X, Xie H, Li H, Li Y, Zhang W
Sci Rep 2018 Apr 26;8(1):6619. doi: 10.1038/s41598-018-24130-7. PMID: 29700349Free PMC Article
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;2015(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906Free PMC Article
Features analysis on Traditional Chinese Medicine syndromes in patients with diabetic peripheral neuropathy.
Li M, Su H, Xiang Y, Zhang J, Zhao J, Lin L
J Tradit Chin Med 2013 Oct;33(5):637-41. doi: 10.1016/s0254-6272(14)60034-0. PMID: 24660588
Clinical and experimental studies on yang-deficiency.
Zhang JQ
J Tradit Chin Med 1982 Sep;2(3):237-42. PMID: 6765852

Therapy

Dose-effect of long-snake-like moxibustion for chronic fatigue syndrome: a randomized controlled trial.
Luo H, Gong R, Zheng R, Tan J, Chen R, Wu J, Ma T
J Transl Med 2023 Jul 3;21(1):430. doi: 10.1186/s12967-023-04250-z. PMID: 37400824Free PMC Article
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;2015(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906Free PMC Article
Yang-tonifying traditional Chinese medicinal plants and their potential phytoandrogenic activity.
Edouard MJ, Miao L, Fan GW, Ojong BB, Zhen H, Zhang J, Gao XM, Zhu Y
Chin J Nat Med 2014 May;12(5):321-34. doi: 10.1016/S1875-5364(14)60040-6. PMID: 24856755
The genus Cynomorium in China: an ethnopharmacological and phytochemical review.
Cui Z, Guo Z, Miao J, Wang Z, Li Q, Chai X, Li M
J Ethnopharmacol 2013 May 2;147(1):1-15. Epub 2013 Jan 29 doi: 10.1016/j.jep.2013.01.020. PMID: 23369691

Prognosis

Dose-effect of long-snake-like moxibustion for chronic fatigue syndrome: a randomized controlled trial.
Luo H, Gong R, Zheng R, Tan J, Chen R, Wu J, Ma T
J Transl Med 2023 Jul 3;21(1):430. doi: 10.1186/s12967-023-04250-z. PMID: 37400824Free PMC Article
miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution.
Chen Y, Wu Y, Yao H, Luo H, Lin B, Zhang X, Liang X, Sun R, Zhao S, Li Y, Zheng Y, Li L, Wang Q
Cell Physiol Biochem 2018;49(5):2088-2098. Epub 2018 Sep 24 doi: 10.1159/000493769. PMID: 30248664
High-throughput chinmedomics-based prediction of effective components and targets from herbal medicine AS1350.
Liu Q, Zhang A, Wang L, Yan G, Zhao H, Sun H, Zou S, Han J, Ma CW, Kong L, Zhou X, Nan Y, Wang X
Sci Rep 2016 Dec 2;6:38437. doi: 10.1038/srep38437. PMID: 27910928Free PMC Article
Effects of symptoms and complementary and alternative medicine use on the yang deficiency pattern among breast cancer patients receiving chemotherapy.
Huang SM, Chien LY, Tai CJ, Chen PH, Lien PJ, Tai CJ
Complement Ther Med 2015 Apr;23(2):233-41. Epub 2015 Jan 12 doi: 10.1016/j.ctim.2015.01.004. PMID: 25847561
Features analysis on Traditional Chinese Medicine syndromes in patients with diabetic peripheral neuropathy.
Li M, Su H, Xiang Y, Zhang J, Zhao J, Lin L
J Tradit Chin Med 2013 Oct;33(5):637-41. doi: 10.1016/s0254-6272(14)60034-0. PMID: 24660588

Clinical prediction guides

Dose-effect of long-snake-like moxibustion for chronic fatigue syndrome: a randomized controlled trial.
Luo H, Gong R, Zheng R, Tan J, Chen R, Wu J, Ma T
J Transl Med 2023 Jul 3;21(1):430. doi: 10.1186/s12967-023-04250-z. PMID: 37400824Free PMC Article
Efficacy and safety of Chinese herbal medicine Wen Xin granules for the treatment of unstable angina pectoris with Yang deficiency and blood stasis syndrome: study protocol for a randomized controlled trial.
Tian PP, Wu QJ, Li J, Chen HW, Wu J, Deng YW, Xie ZC, Zhao W, Tan YQ
Trials 2021 Nov 13;22(1):798. doi: 10.1186/s13063-021-05771-y. PMID: 34774099Free PMC Article
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
End-to-End syndrome differentiation of Yin deficiency and Yang deficiency in traditional Chinese medicine.
Hu Q, Yu T, Li J, Yu Q, Zhu L, Gu Y
Comput Methods Programs Biomed 2019 Jun;174:9-15. Epub 2018 Oct 16 doi: 10.1016/j.cmpb.2018.10.011. PMID: 30376987
miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution.
Chen Y, Wu Y, Yao H, Luo H, Lin B, Zhang X, Liang X, Sun R, Zhao S, Li Y, Zheng Y, Li L, Wang Q
Cell Physiol Biochem 2018;49(5):2088-2098. Epub 2018 Sep 24 doi: 10.1159/000493769. PMID: 30248664

Recent systematic reviews

The correlation between traditional Chinese medicine constitution and primary osteoporosis: A systematic review and meta-analysis.
Qu Q, Jiang R, Luo F, Mou S, Zhang Z, Zhu W
Medicine (Baltimore) 2024 Sep 13;103(37):e39560. doi: 10.1097/MD.0000000000039560. PMID: 39287293Free PMC Article
A systematic review of traditional uses, phytochemistry, pharmacology and toxicity of Epimedium koreanum Nakai.
Qian HQ, Wu DC, Li CY, Liu XR, Han XK, Peng Y, Zhang H, Zhao BY, Zhao Y
J Ethnopharmacol 2024 Jan 10;318(Pt B):116957. Epub 2023 Aug 6 doi: 10.1016/j.jep.2023.116957. PMID: 37544344
Correlation between TCM Constitutional Types and Lung Carcinoma in Various Geographical Areas: A Systematic Review and Meta-Analysis.
Yu X, Yan L, Lan Q, Wan L, Xiong J, Zhang L, Nie H, Ding Z
Contrast Media Mol Imaging 2022;2022:5660231. Epub 2022 Aug 17 doi: 10.1155/2022/5660231. PMID: 36072639Free PMC Article
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;2015(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906Free PMC Article
The association between blood lipid and phlegm turbidity syndrome of angina pectoris: a systematic review and meta-analysis.
Kong D, Wang Y, Liu Y, Zhang Z, Liu G, Qi W, Xiao L, Yuan D, Yang G
Complement Ther Med 2014 Aug;22(4):801-13. Epub 2014 May 27 doi: 10.1016/j.ctim.2014.05.008. PMID: 25146084

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