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Malabsorption syndrome

MedGen UID:: 44256
•Concept ID:: C0024523
•: Disease or Syndrome

Synonyms:	Malabsorption Syndrome; Malabsorption Syndromes; Syndrome, Malabsorption; Syndromes, Malabsorption
SNOMED CT:	Intestinal malabsorption (197476001); Malabsorption syndrome (32230006); Malabsorption (32230006)

Monarch Initiative:	MONDO:0020598

Definition

A syndrome resulting from the inadequate absorption of nutrients in the small intestine. Symptoms include abdominal pain, bloating, and diarrhea. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMalabsorption syndrome

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of gastrointestinal tract
        Intestinal disorder
        Malabsorption syndrome
        Autoimmune enteropathy
        MHC class II deficiency
        MHC class II deficiency 1
        MHC class II deficiency 2
        MHC class II deficiency 3
        MHC class II deficiency 4
        MHC class II deficiency 5
        Primary autoimmune enteropathy
        Severe combined immunodeficiency due to LCK deficiency
        TCR-alpha-beta-positive T-cell deficiency
        Blind loop syndrome
        Celiac disease
        Celiac disease, susceptibility to, 1
        Celiac disease, susceptibility to, 2
        Celiac disease, susceptibility to, 3
        Celiac disease, susceptibility to, 4
        Celiac disease, susceptibility to, 5
        Celiac disease, susceptibility to, 6
        Celiac disease, susceptibility to, 7
        Celiac disease, susceptibility to, 8
        Celiac disease, susceptibility to, 9
        Celiac disease, susceptibility to, 10
        Celiac disease, susceptibility to, 11
        Celiac disease, susceptibility to, 12
        Celiac disease, susceptibility to, 13
        Collagenous sprue
        Hyperhomocysteinemia
        Homocystinuria
        Arakawa syndrome 2
        Methylcobalamin deficiency type cblE
        Intestinal Disaccharidase Deficiency and Disaccharide Malabsorption
        Lactose intolerance
        Short bowel syndrome
        Secondary short bowel syndrome
        Steatorrhea
        Tropical sprue
        Whipple disease

Professional guidelines

PubMed

Incidence, Diagnosis and Management of Malabsorption Following Oesophagectomy: a Systematic Review.

Khaw RA, Nevins EJ, Phillips AW
J Gastrointest Surg 2022 Aug;26(8):1781-1790. Epub 2022 Apr 28 doi: 10.1007/s11605-022-05323-y. PMID: 35484473

Management of pancreatic exocrine insufficiency.

Dominguez-Muñoz JE
Curr Opin Gastroenterol 2019 Sep;35(5):455-459. doi: 10.1097/MOG.0000000000000562. PMID: 31219829

TREATMENT OF MALABSORPTION SYNDROME.

BECK IT
Can Med Assoc J 1964 Aug 8;91(6):301-2. PMID: 14180536 Free PMC Article

See all (32)

Recent clinical studies

Etiology

Small Intestinal Bacterial Overgrowth.

Bushyhead D, Quigley EM
Gastroenterol Clin North Am 2021 Jun;50(2):463-474. Epub 2021 Apr 23 doi: 10.1016/j.gtc.2021.02.008. PMID: 34024452

Management of pancreatic exocrine insufficiency.

Dominguez-Muñoz JE
Curr Opin Gastroenterol 2019 Sep;35(5):455-459. doi: 10.1097/MOG.0000000000000562. PMID: 31219829

The Spectrum of Small Intestinal Bacterial Overgrowth (SIBO).

Quigley EMM
Curr Gastroenterol Rep 2019 Jan 15;21(1):3. doi: 10.1007/s11894-019-0671-z. PMID: 30645678

Evaluation of small bowel bacterial overgrowth.

Schiller LR
Curr Gastroenterol Rep 2007 Oct;9(5):373-7. doi: 10.1007/s11894-007-0045-9. PMID: 17991337

Persistent post-enteritis diarrhoea.

Zoppi G, Deganello A, Gaburro D
Eur J Pediatr 1977 Nov 4;126(4):225-36. doi: 10.1007/BF00477048. PMID: 590275

See all (121)

Diagnosis

Small Intestinal Bacterial Overgrowth.

Bushyhead D, Quigley EM
Gastroenterol Clin North Am 2021 Jun;50(2):463-474. Epub 2021 Apr 23 doi: 10.1016/j.gtc.2021.02.008. PMID: 34024452

The Spectrum of Small Intestinal Bacterial Overgrowth (SIBO).

Quigley EMM
Curr Gastroenterol Rep 2019 Jan 15;21(1):3. doi: 10.1007/s11894-019-0671-z. PMID: 30645678

Malabsorption Syndromes.

Clark R, Johnson R
Nurs Clin North Am 2018 Sep;53(3):361-374. Epub 2018 Jul 11 doi: 10.1016/j.cnur.2018.05.001. PMID: 30100002

Persistent post-enteritis diarrhoea.

Zoppi G, Deganello A, Gaburro D
Eur J Pediatr 1977 Nov 4;126(4):225-36. doi: 10.1007/BF00477048. PMID: 590275

Malabsorption syndrome.

Sleisenger MH
N Engl J Med 1969 Nov 13;281(20):1111-7. doi: 10.1056/NEJM196911132812010. PMID: 4898731

See all (265)

Therapy

Small Intestinal Bacterial Overgrowth.

Bushyhead D, Quigley EM
Gastroenterol Clin North Am 2021 Jun;50(2):463-474. Epub 2021 Apr 23 doi: 10.1016/j.gtc.2021.02.008. PMID: 34024452

Small Intestinal Bacterial Overgrowth and Other Intestinal Disorders.

Ghoshal UC, Ghoshal U
Gastroenterol Clin North Am 2017 Mar;46(1):103-120. doi: 10.1016/j.gtc.2016.09.008. PMID: 28164845

Discovery of human zinc deficiency: its impact on human health and disease.

Prasad AS
Adv Nutr 2013 Mar 1;4(2):176-90. doi: 10.3945/an.112.003210. PMID: 23493534 Free PMC Article

Letter: malabsorption syndrome.

Chakraborty P, Sen D, Paul KR
J Indian Med Assoc 1974 May 1;62(9):329. PMID: 4436553

The malabsorption syndrome.

Escovitz GH, Rubin W
Med Clin North Am 1973 Jul;57(4):907-23. doi: 10.1016/s0025-7125(16)32241-6. PMID: 4197139

See all (146)

Prognosis

Malabsorption Syndromes.

Clark R, Johnson R
Nurs Clin North Am 2018 Sep;53(3):361-374. Epub 2018 Jul 11 doi: 10.1016/j.cnur.2018.05.001. PMID: 30100002

Endoscopic tools for the diagnosis and evaluation of celiac disease.

Ianiro G, Gasbarrini A, Cammarota G
World J Gastroenterol 2013 Dec 14;19(46):8562-70. doi: 10.3748/wjg.v19.i46.8562. PMID: 24379573 Free PMC Article

Evaluation of small bowel bacterial overgrowth.

Schiller LR
Curr Gastroenterol Rep 2007 Oct;9(5):373-7. doi: 10.1007/s11894-007-0045-9. PMID: 17991337

Malabsorption syndromes.

Salerno G, De Franco A, La Rosa S, Calistro V
Rays 2002 Jan-Mar;27(1):19-34. PMID: 12696272

Malabsorption syndrome.

Q Med Rev 1969 Jan;19(3):1-36. PMID: 4895624

See all (80)

Clinical prediction guides

Endoscopic tools for the diagnosis and evaluation of celiac disease.

Ianiro G, Gasbarrini A, Cammarota G
World J Gastroenterol 2013 Dec 14;19(46):8562-70. doi: 10.3748/wjg.v19.i46.8562. PMID: 24379573 Free PMC Article

Discovery of human zinc deficiency: its impact on human health and disease.

Prasad AS
Adv Nutr 2013 Mar 1;4(2):176-90. doi: 10.3945/an.112.003210. PMID: 23493534 Free PMC Article

Whipple's disease: a rare disease revisited.

Afshar P, Redfield DC, Higginbottom PA
Curr Gastroenterol Rep 2010 Aug;12(4):263-9. doi: 10.1007/s11894-010-0110-7. PMID: 20532708

Juvenile dermatitis herpetiformis.

Diaz LA, Lamkin BC, Dubin HV
Arch Dermatol 1979 May;115(5):584-6. PMID: 375840

Tertiary hyperparathyroidism.

Davies DR, Dent CE, Watson L
Br Med J 1968 Aug 17;3(5615):395-9. doi: 10.1136/bmj.3.5615.395. PMID: 5691200 Free PMC Article

See all (82)

Recent systematic reviews

Incidence, Diagnosis and Management of Malabsorption Following Oesophagectomy: a Systematic Review.

Khaw RA, Nevins EJ, Phillips AW
J Gastrointest Surg 2022 Aug;26(8):1781-1790. Epub 2022 Apr 28 doi: 10.1007/s11605-022-05323-y. PMID: 35484473

Prevalence of celiac disease in Iranian patients with type 1 diabetes: A systematic review and meta-analysis.

Gheshlagh RG, Rezaei H, Goli M, Ausili D, Dalvand S, Ghafouri H, Dehkordi AH
Indian J Gastroenterol 2020 Oct;39(5):419-425. Epub 2020 Dec 1 doi: 10.1007/s12664-020-01046-7. PMID: 33263176

Clinical, endoscopic, and histological differentiation between celiac disease and tropical sprue: A systematic review.

Sharma P, Baloda V, Gahlot GP, Singh A, Mehta R, Vishnubathla S, Kapoor K, Ahuja V, Gupta SD, Makharia GK, Das P
J Gastroenterol Hepatol 2019 Jan;34(1):74-83. Epub 2018 Aug 30 doi: 10.1111/jgh.14403. PMID: 30069926

See all (3)

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Malabsorption syndrome

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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