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Type 1 diabetes mellitus 24(T1D24)

MedGen UID:
442792
Concept ID:
C2751697
Disease or Syndrome
Synonyms: Diabetes mellitus, insulin-dependent, 24; T1D24
 
Monarch Initiative: MONDO:0013078
OMIM®: 613006

Definition

An inherited susceptibility or predisposition to developing type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 10q23.31. [from MONDO]

Professional guidelines

PubMed

Winkley K, Upsher R, Stahl D, Pollard D, Kasera A, Brennan A, Heller S, Ismail K
Health Technol Assess 2020 Jun;24(28):1-232. doi: 10.3310/hta24280. PMID: 32568666Free PMC Article
Reynolds AN, Akerman AP, Mann J
PLoS Med 2020 Mar;17(3):e1003053. Epub 2020 Mar 6 doi: 10.1371/journal.pmed.1003053. PMID: 32142510Free PMC Article
Gross JL, de Azevedo MJ, Silveiro SP, Canani LH, Caramori ML, Zelmanovitz T
Diabetes Care 2005 Jan;28(1):164-76. doi: 10.2337/diacare.28.1.164. PMID: 15616252

Recent clinical studies

Etiology

Park J, Ntelis S, Yunasan E, Downton KD, Yip TC, Munir KM, Haq N
J Clin Endocrinol Metab 2023 Dec 21;109(1):279-292. doi: 10.1210/clinem/dgad471. PMID: 37561012
Pal R, Bhadada SK
Curr Opin Endocrinol Diabetes Obes 2021 Aug 1;28(4):383-389. doi: 10.1097/MED.0000000000000640. PMID: 33978603
Sanz M, Ceriello A, Buysschaert M, Chapple I, Demmer RT, Graziani F, Herrera D, Jepsen S, Lione L, Madianos P, Mathur M, Montanya E, Shapira L, Tonetti M, Vegh D
J Clin Periodontol 2018 Feb;45(2):138-149. Epub 2017 Dec 26 doi: 10.1111/jcpe.12808. PMID: 29280174
Rich SS
Curr Opin Endocrinol Diabetes Obes 2017 Aug;24(4):279-284. doi: 10.1097/MED.0000000000000347. PMID: 28509690Free PMC Article
Shapiro AM, Pokrywczynska M, Ricordi C
Nat Rev Endocrinol 2017 May;13(5):268-277. Epub 2016 Nov 11 doi: 10.1038/nrendo.2016.178. PMID: 27834384

Diagnosis

Vanderniet JA, Jenkins AJ, Donaghue KC
Curr Cardiol Rep 2022 Oct;24(10):1455-1465. Epub 2022 Aug 17 doi: 10.1007/s11886-022-01762-w. PMID: 35976602
Ziegler AG, Kick K, Bonifacio E, Haupt F, Hippich M, Dunstheimer D, Lang M, Laub O, Warncke K, Lange K, Assfalg R, Jolink M, Winkler C, Achenbach P; Fr1da Study Group
JAMA 2020 Jan 28;323(4):339-351. doi: 10.1001/jama.2019.21565. PMID: 31990315Free PMC Article
de Filette JMK, Pen JJ, Decoster L, Vissers T, Bravenboer B, Van der Auwera BJ, Gorus FK, Roep BO, Aspeslagh S, Neyns B, Velkeniers B, Kharagjitsingh AV
Eur J Endocrinol 2019 Sep;181(3):363-374. doi: 10.1530/EJE-19-0291. PMID: 31330498Free PMC Article
Sanz M, Ceriello A, Buysschaert M, Chapple I, Demmer RT, Graziani F, Herrera D, Jepsen S, Lione L, Madianos P, Mathur M, Montanya E, Shapira L, Tonetti M, Vegh D
J Clin Periodontol 2018 Feb;45(2):138-149. Epub 2017 Dec 26 doi: 10.1111/jcpe.12808. PMID: 29280174
Shapiro AM, Pokrywczynska M, Ricordi C
Nat Rev Endocrinol 2017 May;13(5):268-277. Epub 2016 Nov 11 doi: 10.1038/nrendo.2016.178. PMID: 27834384

Therapy

Leelarathna L, Evans ML, Neupane S, Rayman G, Lumley S, Cranston I, Narendran P, Barnard-Kelly K, Sutton CJ, Elliott RA, Taxiarchi VP, Gkountouras G, Burns M, Mubita W, Kanumilli N, Camm M, Thabit H, Wilmot EG; FLASH-UK Trial Study Group
N Engl J Med 2022 Oct 20;387(16):1477-1487. Epub 2022 Oct 5 doi: 10.1056/NEJMoa2205650. PMID: 36198143
Ovalle F, Grimes T, Xu G, Patel AJ, Grayson TB, Thielen LA, Li P, Shalev A
Nat Med 2018 Aug;24(8):1108-1112. Epub 2018 Jul 9 doi: 10.1038/s41591-018-0089-4. PMID: 29988125Free PMC Article
Feig DS, Donovan LE, Corcoy R, Murphy KE, Amiel SA, Hunt KF, Asztalos E, Barrett JFR, Sanchez JJ, de Leiva A, Hod M, Jovanovic L, Keely E, McManus R, Hutton EK, Meek CL, Stewart ZA, Wysocki T, O'Brien R, Ruedy K, Kollman C, Tomlinson G, Murphy HR; CONCEPTT Collaborative Group
Lancet 2017 Nov 25;390(10110):2347-2359. Epub 2017 Sep 15 doi: 10.1016/S0140-6736(17)32400-5. PMID: 28923465Free PMC Article
Shapiro AM, Pokrywczynska M, Ricordi C
Nat Rev Endocrinol 2017 May;13(5):268-277. Epub 2016 Nov 11 doi: 10.1038/nrendo.2016.178. PMID: 27834384
Herold KC, Hagopian W, Auger JA, Poumian-Ruiz E, Taylor L, Donaldson D, Gitelman SE, Harlan DM, Xu D, Zivin RA, Bluestone JA
N Engl J Med 2002 May 30;346(22):1692-8. doi: 10.1056/NEJMoa012864. PMID: 12037148

Prognosis

D'Souza D, Empringham J, Pechlivanoglou P, Uleryk EM, Cohen E, Shulman R
JAMA Netw Open 2023 Jun 1;6(6):e2321281. doi: 10.1001/jamanetworkopen.2023.21281. PMID: 37389869Free PMC Article
Vanderniet JA, Jenkins AJ, Donaghue KC
Curr Cardiol Rep 2022 Oct;24(10):1455-1465. Epub 2022 Aug 17 doi: 10.1007/s11886-022-01762-w. PMID: 35976602
Ziegler AG, Kick K, Bonifacio E, Haupt F, Hippich M, Dunstheimer D, Lang M, Laub O, Warncke K, Lange K, Assfalg R, Jolink M, Winkler C, Achenbach P; Fr1da Study Group
JAMA 2020 Jan 28;323(4):339-351. doi: 10.1001/jama.2019.21565. PMID: 31990315Free PMC Article
Jiang P, Li H, Li X
Clin Exp Rheumatol 2015 Jan-Feb;33(1):115-21. Epub 2014 Dec 22 PMID: 25535750
Deng L, Gui Z, Zhao L, Wang J, Shen L
Dig Dis Sci 2012 Jun;57(6):1576-85. Epub 2012 Feb 17 doi: 10.1007/s10620-012-2055-1. PMID: 22350783

Clinical prediction guides

Taylor PN, Collins KS, Lam A, Karpen SR, Greeno B, Walker F, Lozano A, Atabakhsh E, Ahmed ST, Marinac M, Latres E, Senior PA, Rigby M, Gottlieb PA, Dayan CM; Trial Outcome Markers Initiative collaboration
Lancet Diabetes Endocrinol 2023 Dec;11(12):915-925. Epub 2023 Nov 3 doi: 10.1016/S2213-8587(23)00267-X. PMID: 37931637
Park J, Ntelis S, Yunasan E, Downton KD, Yip TC, Munir KM, Haq N
J Clin Endocrinol Metab 2023 Dec 21;109(1):279-292. doi: 10.1210/clinem/dgad471. PMID: 37561012
Ziegler AG, Kick K, Bonifacio E, Haupt F, Hippich M, Dunstheimer D, Lang M, Laub O, Warncke K, Lange K, Assfalg R, Jolink M, Winkler C, Achenbach P; Fr1da Study Group
JAMA 2020 Jan 28;323(4):339-351. doi: 10.1001/jama.2019.21565. PMID: 31990315Free PMC Article
Feig DS, Donovan LE, Corcoy R, Murphy KE, Amiel SA, Hunt KF, Asztalos E, Barrett JFR, Sanchez JJ, de Leiva A, Hod M, Jovanovic L, Keely E, McManus R, Hutton EK, Meek CL, Stewart ZA, Wysocki T, O'Brien R, Ruedy K, Kollman C, Tomlinson G, Murphy HR; CONCEPTT Collaborative Group
Lancet 2017 Nov 25;390(10110):2347-2359. Epub 2017 Sep 15 doi: 10.1016/S0140-6736(17)32400-5. PMID: 28923465Free PMC Article
Rich SS
Curr Opin Endocrinol Diabetes Obes 2017 Aug;24(4):279-284. doi: 10.1097/MED.0000000000000347. PMID: 28509690Free PMC Article

Recent systematic reviews

D'Souza D, Empringham J, Pechlivanoglou P, Uleryk EM, Cohen E, Shulman R
JAMA Netw Open 2023 Jun 1;6(6):e2321281. doi: 10.1001/jamanetworkopen.2023.21281. PMID: 37389869Free PMC Article
Nourelden AZ, Elshanbary AA, El-Sherif L, Benmelouka AY, Rohim HI, Helmy SK, Sayed MK, Ismail A, Ali AS, Ragab KM, Zaazouee MS
Endocr Metab Immune Disord Drug Targets 2021;21(10):1895-1904. doi: 10.2174/1871530320999201209222921. PMID: 33302842
Winkley K, Upsher R, Stahl D, Pollard D, Kasera A, Brennan A, Heller S, Ismail K
Health Technol Assess 2020 Jun;24(28):1-232. doi: 10.3310/hta24280. PMID: 32568666Free PMC Article
Reynolds AN, Akerman AP, Mann J
PLoS Med 2020 Mar;17(3):e1003053. Epub 2020 Mar 6 doi: 10.1371/journal.pmed.1003053. PMID: 32142510Free PMC Article
de Filette JMK, Pen JJ, Decoster L, Vissers T, Bravenboer B, Van der Auwera BJ, Gorus FK, Roep BO, Aspeslagh S, Neyns B, Velkeniers B, Kharagjitsingh AV
Eur J Endocrinol 2019 Sep;181(3):363-374. doi: 10.1530/EJE-19-0291. PMID: 31330498Free PMC Article

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