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Delirium Due to a General Medical Condition

MedGen UID:
452767
Concept ID:
C0860621
Mental or Behavioral Dysfunction

Definition

A disorder characterized by the acute and sudden development of changes in attention, memory, language and/or perception that can be etiologically linked to the direct physiological consequences of a general medical condition. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDelirium Due to a General Medical Condition

Professional guidelines

PubMed

Latronico N, Rasulo FA, Eikermann M, Piva S
Crit Care 2023 Nov 13;27(1):439. doi: 10.1186/s13054-023-04676-3. PMID: 37957759Free PMC Article
McKeith IG, Ferman TJ, Thomas AJ, Blanc F, Boeve BF, Fujishiro H, Kantarci K, Muscio C, O'Brien JT, Postuma RB, Aarsland D, Ballard C, Bonanni L, Donaghy P, Emre M, Galvin JE, Galasko D, Goldman JG, Gomperts SN, Honig LS, Ikeda M, Leverenz JB, Lewis SJG, Marder KS, Masellis M, Salmon DP, Taylor JP, Tsuang DW, Walker Z, Tiraboschi P; prodromal DLB Diagnostic Study Group
Neurology 2020 Apr 28;94(17):743-755. Epub 2020 Apr 2 doi: 10.1212/WNL.0000000000009323. PMID: 32241955Free PMC Article
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article

Recent clinical studies

Etiology

Fong TG, Inouye SK
Nat Rev Neurol 2022 Oct;18(10):579-596. Epub 2022 Aug 26 doi: 10.1038/s41582-022-00698-7. PMID: 36028563Free PMC Article
McKeith IG, Ferman TJ, Thomas AJ, Blanc F, Boeve BF, Fujishiro H, Kantarci K, Muscio C, O'Brien JT, Postuma RB, Aarsland D, Ballard C, Bonanni L, Donaghy P, Emre M, Galvin JE, Galasko D, Goldman JG, Gomperts SN, Honig LS, Ikeda M, Leverenz JB, Lewis SJG, Marder KS, Masellis M, Salmon DP, Taylor JP, Tsuang DW, Walker Z, Tiraboschi P; prodromal DLB Diagnostic Study Group
Neurology 2020 Apr 28;94(17):743-755. Epub 2020 Apr 2 doi: 10.1212/WNL.0000000000009323. PMID: 32241955Free PMC Article
Oh ST, Park JY
Korean J Anesthesiol 2019 Feb;72(1):4-12. Epub 2018 Aug 24 doi: 10.4097/kja.d.18.00073.1. PMID: 30139213Free PMC Article
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article
Sachdev PS, Blacker D, Blazer DG, Ganguli M, Jeste DV, Paulsen JS, Petersen RC
Nat Rev Neurol 2014 Nov;10(11):634-42. Epub 2014 Sep 30 doi: 10.1038/nrneurol.2014.181. PMID: 25266297

Diagnosis

Wilson JE, Mart MF, Cunningham C, Shehabi Y, Girard TD, MacLullich AMJ, Slooter AJC, Ely EW
Nat Rev Dis Primers 2020 Nov 12;6(1):90. doi: 10.1038/s41572-020-00223-4. PMID: 33184265Free PMC Article
Chanques G, Constantin JM, Devlin JW, Ely EW, Fraser GL, Gélinas C, Girard TD, Guérin C, Jabaudon M, Jaber S, Mehta S, Langer T, Murray MJ, Pandharipande P, Patel B, Payen JF, Puntillo K, Rochwerg B, Shehabi Y, Strøm T, Olsen HT, Kress JP
Intensive Care Med 2020 Dec;46(12):2342-2356. Epub 2020 Nov 10 doi: 10.1007/s00134-020-06307-9. PMID: 33170331Free PMC Article
Oh ST, Park JY
Korean J Anesthesiol 2019 Feb;72(1):4-12. Epub 2018 Aug 24 doi: 10.4097/kja.d.18.00073.1. PMID: 30139213Free PMC Article
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article
Sachdev PS, Blacker D, Blazer DG, Ganguli M, Jeste DV, Paulsen JS, Petersen RC
Nat Rev Neurol 2014 Nov;10(11):634-42. Epub 2014 Sep 30 doi: 10.1038/nrneurol.2014.181. PMID: 25266297

Therapy

Tiglao SM, Meisenheimer ES, Oh RC
Am Fam Physician 2021 Sep 1;104(3):253-262. PMID: 34523874
Tonna JE, Dalton A, Presson AP, Zhang C, Colantuoni E, Lander K, Howard S, Beynon J, Kamdar BB
Chest 2021 Sep;160(3):899-908. Epub 2021 Mar 24 doi: 10.1016/j.chest.2021.03.030. PMID: 33773988Free PMC Article
Chanques G, Constantin JM, Devlin JW, Ely EW, Fraser GL, Gélinas C, Girard TD, Guérin C, Jabaudon M, Jaber S, Mehta S, Langer T, Murray MJ, Pandharipande P, Patel B, Payen JF, Puntillo K, Rochwerg B, Shehabi Y, Strøm T, Olsen HT, Kress JP
Intensive Care Med 2020 Dec;46(12):2342-2356. Epub 2020 Nov 10 doi: 10.1007/s00134-020-06307-9. PMID: 33170331Free PMC Article
Nisavic M, Nejad SH, Isenberg BM, Bajwa EK, Currier P, Wallace PM, Velmahos G, Wilens T
Psychosomatics 2019 Sep-Oct;60(5):458-467. Epub 2019 Feb 14 doi: 10.1016/j.psym.2019.02.002. PMID: 30876654
Attilia F, Perciballi R, Rotondo C, Capriglione I, Iannuzzi S, Attilia ML, Coriale G, Vitali M, Cereatti F, Fiore M, Ceccanti M; Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip
Riv Psichiatr 2018 May-Jun;53(3):118-122. doi: 10.1708/2925.29413. PMID: 29912213

Prognosis

Fong TG, Inouye SK
Nat Rev Neurol 2022 Oct;18(10):579-596. Epub 2022 Aug 26 doi: 10.1038/s41582-022-00698-7. PMID: 36028563Free PMC Article
Urits I, Peck J, Giacomazzi S, Patel R, Wolf J, Mathew D, Schwartz R, Kassem H, Urman RD, Kaye AD, Viswanath O
Adv Ther 2020 May;37(5):1897-1909. Epub 2020 Apr 9 doi: 10.1007/s12325-020-01317-x. PMID: 32274749
Oh ST, Park JY
Korean J Anesthesiol 2019 Feb;72(1):4-12. Epub 2018 Aug 24 doi: 10.4097/kja.d.18.00073.1. PMID: 30139213Free PMC Article
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article
Marcantonio ER
N Engl J Med 2017 Oct 12;377(15):1456-1466. doi: 10.1056/NEJMcp1605501. PMID: 29020579Free PMC Article

Clinical prediction guides

Eijlers R, Dierckx B, Staals LM, Berghmans JM, van der Schroeff MP, Strabbing EM, Wijnen RMH, Hillegers MHJ, Legerstee JS, Utens EMWJ
Eur J Anaesthesiol 2019 Oct;36(10):728-737. doi: 10.1097/EJA.0000000000001059. PMID: 31356373Free PMC Article
Magnuson A, Sattar S, Nightingale G, Saracino R, Skonecki E, Trevino KM
Am Soc Clin Oncol Educ Book 2019 Jan;39:e96-e109. Epub 2019 May 17 doi: 10.1200/EDBK_237641. PMID: 31099668
Miller D, Lewis SR, Pritchard MW, Schofield-Robinson OJ, Shelton CL, Alderson P, Smith AF
Cochrane Database Syst Rev 2018 Aug 21;8(8):CD012317. doi: 10.1002/14651858.CD012317.pub2. PMID: 30129968Free PMC Article
Norris D, Clark MS, Shipley S
Am Fam Physician 2016 Oct 15;94(8):635-641. PMID: 27929229
Weingart SD, Trueger NS, Wong N, Scofi J, Singh N, Rudolph SS
Ann Emerg Med 2015 Apr;65(4):349-55. Epub 2014 Oct 23 doi: 10.1016/j.annemergmed.2014.09.025. PMID: 25447559

Recent systematic reviews

Veronese N, Solimando L, Bolzetta F, Maggi S, Fiedorowicz JG, Gupta A, Fabiano N, Wong S, Boyer L, Fond G, Dragioti E, Dominguez LJ, Barbagallo M, Romagnoli S, Bellelli G, Solmi M
Ageing Res Rev 2024 Jun;97:102313. Epub 2024 Apr 26 doi: 10.1016/j.arr.2024.102313. PMID: 38677599
Kim S, Choi E, Jung Y, Jang I
J Clin Nurs 2023 May;32(9-10):1691-1704. Epub 2021 Dec 8 doi: 10.1111/jocn.16157. PMID: 34881476
Veronese N, Custodero C, Demurtas J, Smith L, Barbagallo M, Maggi S, Cella A, Vanacore N, Aprile PL, Ferrucci L, Pilotto A; Special Interest Group in Systematic Reviews of the European Geriatric Medicine Society (EuGMS); Special Interest Group in Meta-analyses and Comprehensive Geriatric Assessment of the European Geriatric Medicine Society (EuGMS)
Age Ageing 2022 May 1;51(5) doi: 10.1093/ageing/afac104. PMID: 35524746
Miller D, Lewis SR, Pritchard MW, Schofield-Robinson OJ, Shelton CL, Alderson P, Smith AF
Cochrane Database Syst Rev 2018 Aug 21;8(8):CD012317. doi: 10.1002/14651858.CD012317.pub2. PMID: 30129968Free PMC Article
Fuke R, Hifumi T, Kondo Y, Hatakeyama J, Takei T, Yamakawa K, Inoue S, Nishida O
BMJ Open 2018 May 5;8(5):e019998. doi: 10.1136/bmjopen-2017-019998. PMID: 29730622Free PMC Article

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