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Esophageal Mucosa-Associated Lymphoid Tissue Lymphoma

MedGen UID:
459495
•Concept ID:
C2987269
•
Neoplastic Process
Synonym: Esophageal MALT Lymphoma

Definition

An extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue that arises from the esophagus with the bulk of the mass located in the esophagus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEsophageal Mucosa-Associated Lymphoid Tissue Lymphoma

Professional guidelines

PubMed

An evidence-based consensus statement on the role and application of endosonography in clinical practice.
Maluf-Filho F, Dotti CM, Halwan B, Queiros AF, Kupski C, Chaves DM, Nakao FS, Kumar A
Endoscopy 2009 Nov;41(11):979-87. Epub 2009 Oct 28 doi: 10.1055/s-0029-1215192. PMID: 19866396
Endoscopic tumor diagnosis and treatment.
Kida M
Endoscopy 2002 Nov;34(11):860-70. doi: 10.1055/s-2002-35311. PMID: 12430069
Helicobacter pylori infection--current treatment practice.
Xia HH, Yu Wong BC, Talley NJ, Lam SK
Expert Opin Pharmacother 2001 Feb;2(2):253-66. doi: 10.1517/14656566.2.2.253. PMID: 11336584

Recent clinical studies

Etiology

Revealing the clinical impact of MTOR and ARID2 gene mutations on MALT lymphoma of the alimentary canal using targeted sequencing.
Huang X, Zeng J, Luo Y, Luo S, Li Y, Wang J
Diagn Pathol 2024 Jul 25;19(1):102. doi: 10.1186/s13000-024-01525-x. PMID: 39054516Free PMC Article
Helicobacter pylori, gastric cancer and other gastrointestinal malignancies.
Venerito M, Vasapolli R, Rokkas T, Delchier JC, Malfertheiner P
Helicobacter 2017 Sep;22 Suppl 1 doi: 10.1111/hel.12413. PMID: 28891127
Eradication of Helicobacter pylori and Gastric Cancer: A Systematic Review and Meta-analysis of Cohort Studies.
Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
J Natl Cancer Inst 2016 Sep;108(9) Epub 2016 Jul 14 doi: 10.1093/jnci/djw132. PMID: 27416750
Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma: magnifying endoscopy findings.
Law TT, Tong D, Wong SW, Chan SY, Law S
Hong Kong Med J 2015 Apr;21(2):183-6. doi: 10.12809/hkmj134208. PMID: 25904569
Primary lymphomas in the gastrointestinal tract.
Peng JC, Zhong L, Ran ZH
J Dig Dis 2015 Apr;16(4):169-76. doi: 10.1111/1751-2980.12234. PMID: 25678011

Diagnosis

Pitfalls in gastrointestinal tract haematopoietic lesions.
Alvarez-Lesmes J, Chapman JR, Poveda JC
Pathology 2022 Mar;54(2):177-183. Epub 2021 Nov 18 doi: 10.1016/j.pathol.2021.08.010. PMID: 34801278
Primary esophageal mucosa-associated lymphoid tissue lymphoma: A case report and review of literature.
Ma Q, Zhang C, Fang S, Zhong P, Zhu X, Lin L, Xiao H
Medicine (Baltimore) 2017 Mar;96(13):e6478. doi: 10.1097/MD.0000000000006478. PMID: 28353588Free PMC Article
Primary esophageal mucosa-associated lymphoid tissue lymphoma diagnosed by using stacked forceps biopsy.
Lee DS, Ahn YC, Eom DW, Lee SJ
Dis Esophagus 2016 Oct;29(7):887-890. Epub 2015 Jan 27 doi: 10.1111/dote.12309. PMID: 25626120
Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma: magnifying endoscopy findings.
Law TT, Tong D, Wong SW, Chan SY, Law S
Hong Kong Med J 2015 Apr;21(2):183-6. doi: 10.12809/hkmj134208. PMID: 25904569
Primary lymphomas in the gastrointestinal tract.
Peng JC, Zhong L, Ran ZH
J Dig Dis 2015 Apr;16(4):169-76. doi: 10.1111/1751-2980.12234. PMID: 25678011

Therapy

The Progression of Esophageal Mucosa-associated Lymphoid Tissue Lymphoma after Helicobacter pylori Eradication Therapy: A Case Report and Discussion of Therapeutic Options.
Takeuchi Y, Miyahara K, Morito T, Okikawa Y, Kinugasa H, Moritou Y, Higashi R, Kunihiro M, Nakagawa M
Intern Med 2019 Jan 15;58(2):207-212. Epub 2018 Aug 24 doi: 10.2169/internalmedicine.1112-18. PMID: 30146577Free PMC Article
Eradication of Helicobacter pylori and Gastric Cancer: A Systematic Review and Meta-analysis of Cohort Studies.
Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
J Natl Cancer Inst 2016 Sep;108(9) Epub 2016 Jul 14 doi: 10.1093/jnci/djw132. PMID: 27416750
Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma: magnifying endoscopy findings.
Law TT, Tong D, Wong SW, Chan SY, Law S
Hong Kong Med J 2015 Apr;21(2):183-6. doi: 10.12809/hkmj134208. PMID: 25904569
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report.
Malfertheiner P, Megraud F, O'Morain C, Bazzoli F, El-Omar E, Graham D, Hunt R, Rokkas T, Vakil N, Kuipers EJ
Gut 2007 Jun;56(6):772-81. Epub 2006 Dec 14 doi: 10.1136/gut.2006.101634. PMID: 17170018Free PMC Article
Gastrointestinal complications in renal transplant recipients.
Ponticelli C, Passerini P
Transpl Int 2005 Jun;18(6):643-50. doi: 10.1111/j.1432-2277.2005.00134.x. PMID: 15910287

Prognosis

Revealing the clinical impact of MTOR and ARID2 gene mutations on MALT lymphoma of the alimentary canal using targeted sequencing.
Huang X, Zeng J, Luo Y, Luo S, Li Y, Wang J
Diagn Pathol 2024 Jul 25;19(1):102. doi: 10.1186/s13000-024-01525-x. PMID: 39054516Free PMC Article
Helicobacter pylori, gastric cancer and other gastrointestinal malignancies.
Venerito M, Vasapolli R, Rokkas T, Delchier JC, Malfertheiner P
Helicobacter 2017 Sep;22 Suppl 1 doi: 10.1111/hel.12413. PMID: 28891127
Primary esophageal mucosa-associated lymphoid tissue lymphoma: A case report and review of literature.
Ma Q, Zhang C, Fang S, Zhong P, Zhu X, Lin L, Xiao H
Medicine (Baltimore) 2017 Mar;96(13):e6478. doi: 10.1097/MD.0000000000006478. PMID: 28353588Free PMC Article
Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma: magnifying endoscopy findings.
Law TT, Tong D, Wong SW, Chan SY, Law S
Hong Kong Med J 2015 Apr;21(2):183-6. doi: 10.12809/hkmj134208. PMID: 25904569
Diagnosis of esophagogastric tumors.
Moretó M
Endoscopy 2001 Jan;33(1):1-7. doi: 10.1055/s-2001-11182. PMID: 11204980

Clinical prediction guides

Helicobacter pylori, gastric cancer and other gastrointestinal malignancies.
Venerito M, Vasapolli R, Rokkas T, Delchier JC, Malfertheiner P
Helicobacter 2017 Sep;22 Suppl 1 doi: 10.1111/hel.12413. PMID: 28891127
Primary esophageal mucosa-associated lymphoid tissue lymphoma: A case report and review of literature.
Ma Q, Zhang C, Fang S, Zhong P, Zhu X, Lin L, Xiao H
Medicine (Baltimore) 2017 Mar;96(13):e6478. doi: 10.1097/MD.0000000000006478. PMID: 28353588Free PMC Article
Radiotherapy for mucosa-associated lymphoid tissue (MALT) lymphoma of the esophagus: a case report with a diagnostic and therapeutic discussion.
Kishi K, Maeda H, Nakamura Y, Shirai S, Sato M
Int J Clin Oncol 2012 Apr;17(2):174-80. Epub 2011 Jun 10 doi: 10.1007/s10147-011-0265-8. PMID: 21660505
Region-specific immunological response of the different laryngeal compartments: significance of larynx-associated lymphoid tissue.
Kutta H, Steven P, Tillmann BN, Tsokos M, Paulsen FP
Cell Tissue Res 2003 Mar;311(3):365-71. Epub 2003 Feb 5 doi: 10.1007/s00441-002-0692-y. PMID: 12658444
A case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus.
Hosaka S, Nakamura N, Akamatsu T, Fujisawa T, Ogiwara Y, Kiyosawa K, Hidaka E, Ota H, Katsuyama T, Inagaki H
Gut 2002 Aug;51(2):281-4. doi: 10.1136/gut.51.2.281. PMID: 12117895Free PMC Article

Recent systematic reviews

Primary esophageal non-Hodgkin's lymphoma: demographics, clinical characteristics, histopathologic types, and survival in 179 patients from the SEER program and systematic review of the literature.
Quiroga-Centeno AC, Bautista-Parada IR, Tapias LF, Gómez-Ochoa SA
Esophagus 2021 Oct;18(4):734-742. Epub 2021 Apr 20 doi: 10.1007/s10388-021-00842-0. PMID: 33880688
Eradication of Helicobacter pylori and Gastric Cancer: A Systematic Review and Meta-analysis of Cohort Studies.
Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
J Natl Cancer Inst 2016 Sep;108(9) Epub 2016 Jul 14 doi: 10.1093/jnci/djw132. PMID: 27416750

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