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Stature quantitative trait locus 22(STQTL22)

MedGen UID:
462143
Concept ID:
C3150793
Finding
Synonym: STQTL22
 
OMIM®: 613547

Recent clinical studies

Etiology

Kemper KE, Sidorenko J, Wang H, Hayes BJ, Wray NR, Yengo L, Keller MC, Goddard M, Visscher PM
Nat Commun 2024 May 6;15(1):3776. doi: 10.1038/s41467-024-47802-7. PMID: 38710707Free PMC Article
Young KL, Fisher V, Deng X, Brody JA, Graff M, Lim E, Lin BM, Xu H, Amin N, An P, Aslibekyan S, Fohner AE, Hidalgo B, Lenzini P, Kraaij R, Medina-Gomez C, Prokić I, Rivadeneira F, Sitlani C, Tao R, van Rooij J, Zhang D, Broome JG, Buth EJ, Heavner BD, Jain D, Smith AV, Barnes K, Boorgula MP, Chavan S, Darbar D, De Andrade M, Guo X, Haessler J, Irvin MR, Kalyani RR, Kardia SLR, Kooperberg C, Kim W, Mathias RA, McDonald ML, Mitchell BD, Peyser PA, Regan EA, Redline S, Reiner AP, Rich SS, Rotter JI, Smith JA, Weiss S, Wiggins KL, Yanek LR, Arnett D, Heard-Costa NL, Leal S, Lin D, McKnight B, Province M, van Duijn CM, North KE, Cupples LA, Liu CT
HGG Adv 2023 Jan 12;4(1):100163. Epub 2022 Nov 25 doi: 10.1016/j.xhgg.2022.100163. PMID: 36568030Free PMC Article
Cho YS, Go MJ, Kim YJ, Heo JY, Oh JH, Ban HJ, Yoon D, Lee MH, Kim DJ, Park M, Cha SH, Kim JW, Han BG, Min H, Ahn Y, Park MS, Han HR, Jang HY, Cho EY, Lee JE, Cho NH, Shin C, Park T, Park JW, Lee JK, Cardon L, Clarke G, McCarthy MI, Lee JY, Lee JK, Oh B, Kim HL
Nat Genet 2009 May;41(5):527-34. Epub 2009 Apr 26 doi: 10.1038/ng.357. PMID: 19396169
Kraft P, Bauman L, Yuan JY, Horvath S; Framingham Heart Study
BMC Genet 2003 Dec 31;4 Suppl 1(Suppl 1):S55. doi: 10.1186/1471-2156-4-S1-S55. PMID: 14975123Free PMC Article
Perola M, Ohman M, Hiekkalinna T, Leppävuori J, Pajukanta P, Wessman M, Koskenvuo M, Palotie A, Lange K, Kaprio J, Peltonen L
Am J Hum Genet 2001 Jul;69(1):117-23. Epub 2001 Jun 15 doi: 10.1086/321286. PMID: 11410840Free PMC Article

Diagnosis

Galván-Femenía I, Obón-Santacana M, Piñeyro D, Guindo-Martinez M, Duran X, Carreras A, Pluvinet R, Velasco J, Ramos L, Aussó S, Mercader JM, Puig L, Perucho M, Torrents D, Moreno V, Sumoy L, de Cid R
J Med Genet 2018 Nov;55(11):765-778. Epub 2018 Aug 30 doi: 10.1136/jmedgenet-2018-105437. PMID: 30166351Free PMC Article

Therapy

Kemper KE, Sidorenko J, Wang H, Hayes BJ, Wray NR, Yengo L, Keller MC, Goddard M, Visscher PM
Nat Commun 2024 May 6;15(1):3776. doi: 10.1038/s41467-024-47802-7. PMID: 38710707Free PMC Article
Taylor DL, Jackson AU, Narisu N, Hemani G, Erdos MR, Chines PS, Swift A, Idol J, Didion JP, Welch RP, Kinnunen L, Saramies J, Lakka TA, Laakso M, Tuomilehto J, Parker SCJ, Koistinen HA, Davey Smith G, Boehnke M, Scott LJ, Birney E, Collins FS
Proc Natl Acad Sci U S A 2019 May 28;116(22):10883-10888. Epub 2019 May 10 doi: 10.1073/pnas.1814263116. PMID: 31076557Free PMC Article
Yengo L, Sidorenko J, Kemper KE, Zheng Z, Wood AR, Weedon MN, Frayling TM, Hirschhorn J, Yang J, Visscher PM; GIANT Consortium
Hum Mol Genet 2018 Oct 15;27(20):3641-3649. doi: 10.1093/hmg/ddy271. PMID: 30124842Free PMC Article
Turner ST, Kardia SL, Boerwinkle E, de Andrade M
Genet Epidemiol 2004 Jul;27(1):64-73. doi: 10.1002/gepi.20002. PMID: 15185404

Prognosis

Taylor DL, Jackson AU, Narisu N, Hemani G, Erdos MR, Chines PS, Swift A, Idol J, Didion JP, Welch RP, Kinnunen L, Saramies J, Lakka TA, Laakso M, Tuomilehto J, Parker SCJ, Koistinen HA, Davey Smith G, Boehnke M, Scott LJ, Birney E, Collins FS
Proc Natl Acad Sci U S A 2019 May 28;116(22):10883-10888. Epub 2019 May 10 doi: 10.1073/pnas.1814263116. PMID: 31076557Free PMC Article
Hsu YH, Estrada K, Evangelou E, Ackert-Bicknell C, Akesson K, Beck T, Brown SJ, Capellini T, Carbone L, Cauley J, Cheung CL, Cummings SR, Czerwinski S, Demissie S, Econs M, Evans D, Farber C, Gautvik K, Harris T, Kammerer C, Kemp J, Koller DL, Kung A, Lawlor D, Lee M, Lorentzon M, McGuigan F, Medina-Gomez C, Mitchell B, Newman A, Nielson C, Ohlsson C, Peacock M, Reppe S, Richards JB, Robbins J, Sigurdsson G, Spector TD, Stefansson K, Streeten E, Styrkarsdottir U, Tobias J, Trajanoska K, Uitterlinden A, Vandenput L, Wilson SG, Yerges-Armstrong L, Young M, Zillikens MC, Rivadeneira F, Kiel DP, Karasik D
J Bone Miner Res 2019 Jul;34(7):1284-1296. Epub 2019 Mar 19 doi: 10.1002/jbmr.3698. PMID: 30888730Free PMC Article
Yengo L, Sidorenko J, Kemper KE, Zheng Z, Wood AR, Weedon MN, Frayling TM, Hirschhorn J, Yang J, Visscher PM; GIANT Consortium
Hum Mol Genet 2018 Oct 15;27(20):3641-3649. doi: 10.1093/hmg/ddy271. PMID: 30124842Free PMC Article
Benyamin B, Pourcain B, Davis OS, Davies G, Hansell NK, Brion MJ, Kirkpatrick RM, Cents RA, Franić S, Miller MB, Haworth CM, Meaburn E, Price TS, Evans DM, Timpson N, Kemp J, Ring S, McArdle W, Medland SE, Yang J, Harris SE, Liewald DC, Scheet P, Xiao X, Hudziak JJ, de Geus EJ; Wellcome Trust Case Control Consortium 2 (WTCCC2), Jaddoe VW, Starr JM, Verhulst FC, Pennell C, Tiemeier H, Iacono WG, Palmer LJ, Montgomery GW, Martin NG, Boomsma DI, Posthuma D, McGue M, Wright MJ, Davey Smith G, Deary IJ, Plomin R, Visscher PM
Mol Psychiatry 2014 Feb;19(2):253-8. Epub 2013 Jan 29 doi: 10.1038/mp.2012.184. PMID: 23358156Free PMC Article
Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Møller E, Marinelli M, Holst C, Leinonen JT, Perry JR, Surakka I, Pietiläinen O, Kettunen J, Anttila V, Kaakinen M, Sovio U, Pouta A, Das S, Lagou V, Power C, Prokopenko I, Evans DM, Kemp JP, St Pourcain B, Ring S, Palotie A, Kajantie E, Osmond C, Lehtimäki T, Viikari JS, Kähönen M, Warrington NM, Lye SJ, Palmer LJ, Tiesler CM, Flexeder C, Montgomery GW, Medland SE, Hofman A, Hakonarson H, Guxens M, Bartels M, Salomaa V; ReproGen Consortium, Murabito JM, Kaprio J, Sørensen TI, Ballester F, Bisgaard H, Boomsma DI, Koppelman GH, Grant SF, Jaddoe VW, Martin NG, Heinrich J, Pennell CE, Raitakari OT, Eriksson JG, Smith GD, Hyppönen E, Järvelin MR, McCarthy MI, Ripatti S, Widén E; Early Growth Genetics (EGG) Consortium
Hum Mol Genet 2013 Jul 1;22(13):2735-47. Epub 2013 Feb 27 doi: 10.1093/hmg/ddt104. PMID: 23449627Free PMC Article

Clinical prediction guides

Young KL, Fisher V, Deng X, Brody JA, Graff M, Lim E, Lin BM, Xu H, Amin N, An P, Aslibekyan S, Fohner AE, Hidalgo B, Lenzini P, Kraaij R, Medina-Gomez C, Prokić I, Rivadeneira F, Sitlani C, Tao R, van Rooij J, Zhang D, Broome JG, Buth EJ, Heavner BD, Jain D, Smith AV, Barnes K, Boorgula MP, Chavan S, Darbar D, De Andrade M, Guo X, Haessler J, Irvin MR, Kalyani RR, Kardia SLR, Kooperberg C, Kim W, Mathias RA, McDonald ML, Mitchell BD, Peyser PA, Regan EA, Redline S, Reiner AP, Rich SS, Rotter JI, Smith JA, Weiss S, Wiggins KL, Yanek LR, Arnett D, Heard-Costa NL, Leal S, Lin D, McKnight B, Province M, van Duijn CM, North KE, Cupples LA, Liu CT
HGG Adv 2023 Jan 12;4(1):100163. Epub 2022 Nov 25 doi: 10.1016/j.xhgg.2022.100163. PMID: 36568030Free PMC Article
Hsu YH, Estrada K, Evangelou E, Ackert-Bicknell C, Akesson K, Beck T, Brown SJ, Capellini T, Carbone L, Cauley J, Cheung CL, Cummings SR, Czerwinski S, Demissie S, Econs M, Evans D, Farber C, Gautvik K, Harris T, Kammerer C, Kemp J, Koller DL, Kung A, Lawlor D, Lee M, Lorentzon M, McGuigan F, Medina-Gomez C, Mitchell B, Newman A, Nielson C, Ohlsson C, Peacock M, Reppe S, Richards JB, Robbins J, Sigurdsson G, Spector TD, Stefansson K, Streeten E, Styrkarsdottir U, Tobias J, Trajanoska K, Uitterlinden A, Vandenput L, Wilson SG, Yerges-Armstrong L, Young M, Zillikens MC, Rivadeneira F, Kiel DP, Karasik D
J Bone Miner Res 2019 Jul;34(7):1284-1296. Epub 2019 Mar 19 doi: 10.1002/jbmr.3698. PMID: 30888730Free PMC Article
Yengo L, Sidorenko J, Kemper KE, Zheng Z, Wood AR, Weedon MN, Frayling TM, Hirschhorn J, Yang J, Visscher PM; GIANT Consortium
Hum Mol Genet 2018 Oct 15;27(20):3641-3649. doi: 10.1093/hmg/ddy271. PMID: 30124842Free PMC Article
Kraft P, Bauman L, Yuan JY, Horvath S; Framingham Heart Study
BMC Genet 2003 Dec 31;4 Suppl 1(Suppl 1):S55. doi: 10.1186/1471-2156-4-S1-S55. PMID: 14975123Free PMC Article
Perola M, Ohman M, Hiekkalinna T, Leppävuori J, Pajukanta P, Wessman M, Koskenvuo M, Palotie A, Lange K, Kaprio J, Peltonen L
Am J Hum Genet 2001 Jul;69(1):117-23. Epub 2001 Jun 15 doi: 10.1086/321286. PMID: 11410840Free PMC Article

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