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Buschke Lowenstein tumor(GCBL)

MedGen UID:
473018
Concept ID:
C0276264
Neoplastic Process
Synonyms: GCBL; Giant condyloma acuminatum involving the prepuce and glans penis
SNOMED CT: Anogenital verrucous carcinoma of Buschke-Löwenstein (402910001); Buschke-Löwenstein tumor of penis (402911002); Buschke-Löwenstein giant condyloma (402910001); Giant acuminate warts (402910001); Anogenital verrucous carcinoma of Buschke-Lowenstein (402910001)
 
Monarch Initiative: MONDO:0027026

Definition

A slow-growing, locally destructive, cauliflower-like condyloma of the anogenital region. It most often appears on the penis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBuschke Lowenstein tumor

Professional guidelines

PubMed

Fawaz B, Vieira C, Decker A, Lawrence N
J Dermatolog Treat 2022 Jun;33(4):1811-1815. Epub 2022 Jun 13 doi: 10.1080/09546634.2021.1914312. PMID: 33849379
Diaz Gómez CJ
Dermatol Ther 2020 Mar;33(2):e13268. Epub 2020 Feb 20 doi: 10.1111/dth.13268. PMID: 32052558
Sonthalia S, Gandhi V, Agrawal M, Sharma P
Int J STD AIDS 2019 Oct;30(11):1136-1139. Epub 2019 Sep 24 doi: 10.1177/0956462419855505. PMID: 31551001

Recent clinical studies

Etiology

Ernez S, Derouich M, Chachia S, Boughizane S
Pan Afr Med J 2022;42:50. Epub 2022 May 18 doi: 10.11604/pamj.2022.42.50.35120. PMID: 35949464Free PMC Article
Purzycka-Bohdan D, Nowicki RJ, Herms F, Casanova JL, Fouéré S, Béziat V
Int J Mol Sci 2022 Apr 20;23(9) doi: 10.3390/ijms23094547. PMID: 35562936Free PMC Article
Nieves-Condoy JF, Acuña-Pinzón CL, Chavarría-Chavira JL, Hinojosa-Ugarte D, Zúñiga-Vázquez LA
Infect Dis Obstet Gynecol 2021;2021:9919446. Epub 2021 Jun 30 doi: 10.1155/2021/9919446. PMID: 34305393Free PMC Article
Spinu D, Rădulescu A, Bratu O, Checheriţă IA, Ranetti AE, Mischianu D; -
Chirurgia (Bucur) 2014 Jul-Aug;109(4):445-50. PMID: 25149605
Gormley RH, Kovarik CL
J Am Acad Dermatol 2012 Jun;66(6):883.e1-17; quiz 899-900. doi: 10.1016/j.jaad.2010.12.049. PMID: 22583721

Diagnosis

Saldivar-Reyes DA, Muñoz-Maldonado GE, Fernández-Treviño JR, Vidal-Torres Ó, Medina-Muñoz DE
Cir Cir 2023;91(6):835-838. doi: 10.24875/CIRU.22000302. PMID: 38096879
Sonthalia S, Gandhi V, Agrawal M, Sharma P
Int J STD AIDS 2019 Oct;30(11):1136-1139. Epub 2019 Sep 24 doi: 10.1177/0956462419855505. PMID: 31551001
Pinto-Gouveia M, Pinho A, Reis JP
Acta Med Port 2016 Mar;29(3):231. Epub 2016 Mar 31 doi: 10.20344/amp.7101. PMID: 27285101
Rodríguez-Gutiérrez R, Rodarte-Shade M, González-Saldivar G, González-González JG
Am J Med Sci 2015 Jan;349(1):e1. doi: 10.1097/MAJ.0000000000000413. PMID: 25535884
Pinto AR, Guedes-Martins L, Marques C, Cabral JM
Acta Med Port 2012 Sep-Oct;25(5):345-7. Epub 2012 Nov 12 PMID: 23211208

Therapy

Sonthalia S, Gandhi V, Agrawal M, Sharma P
Int J STD AIDS 2019 Oct;30(11):1136-1139. Epub 2019 Sep 24 doi: 10.1177/0956462419855505. PMID: 31551001
Bowman IA, Parra A, Arriaga Y
J Oncol Pract 2016 Oct;12(10):951-953. doi: 10.1200/JOP.2016.013441. PMID: 27554523
Rodríguez-Gutiérrez R, Rodarte-Shade M, González-Saldivar G, González-González JG
Am J Med Sci 2015 Jan;349(1):e1. doi: 10.1097/MAJ.0000000000000413. PMID: 25535884
Gormley RH, Kovarik CL
J Am Acad Dermatol 2012 Jun;66(6):883.e1-17; quiz 899-900. doi: 10.1016/j.jaad.2010.12.049. PMID: 22583721
McDuffie RW
Urology 1975 Sep;6(3):397-8. doi: 10.1016/0090-4295(75)90783-9. PMID: 1162826

Prognosis

Cimmino A, Walters E, Gubler A, Ibrahim A
Am J Case Rep 2020 Feb 23;21:e920516. doi: 10.12659/AJCR.920516. PMID: 32088723Free PMC Article
Zhang D, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X
Virchows Arch 2020 Apr;476(4):543-550. Epub 2019 Nov 15 doi: 10.1007/s00428-019-02680-z. PMID: 31728626
Bowman IA, Parra A, Arriaga Y
J Oncol Pract 2016 Oct;12(10):951-953. doi: 10.1200/JOP.2016.013441. PMID: 27554523
Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ
Dis Colon Rectum 1994 Sep;37(9):950-7. doi: 10.1007/BF02052606. PMID: 8076499
DAVIES SW
J Clin Pathol 1965 Mar;18(2):142-9. doi: 10.1136/jcp.18.2.142. PMID: 14276146Free PMC Article

Clinical prediction guides

Saldivar-Reyes DA, Muñoz-Maldonado GE, Fernández-Treviño JR, Vidal-Torres Ó, Medina-Muñoz DE
Cir Cir 2023;91(6):835-838. doi: 10.24875/CIRU.22000302. PMID: 38096879
Taskin OC, Pehlivanoglu B, Reid MD, Friedman T, Lee M, Tadros TS, Bandyopadhyay S, Akinfolarin J, Armutlu A, Basturk O, Adsay V
Turk Patoloji Derg 2021;37(1):18-25. doi: 10.5146/tjpath.2020.01508. PMID: 33021736Free PMC Article
Zhang D, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X
Virchows Arch 2020 Apr;476(4):543-550. Epub 2019 Nov 15 doi: 10.1007/s00428-019-02680-z. PMID: 31728626
Das BB, Anton K, Knox L, Jarin J, Sue PK
Transpl Infect Dis 2018 Dec;20(6):e12989. Epub 2018 Sep 28 doi: 10.1111/tid.12989. PMID: 30184307
Ali Sbai M, Balti W, Dhahak S, Ben Romdhane S, Tabib M, Balti H
Tunis Med 2009 Sep;87(9):627-9. PMID: 20180387

Recent systematic reviews

Ates M, Akbulut S, Tuncer A, Sahin E, Karabulut E, Sarici KB
J Gastrointest Cancer 2022 Dec;53(4):1083-1092. Epub 2021 Oct 25 doi: 10.1007/s12029-021-00713-y. PMID: 34694593

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