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Pineal gland calcification

MedGen UID:
473413
•Concept ID:
C1398718
•
Pathologic Function
Synonym: Calcification of pineal gland
SNOMED CT: Pineal gland calcification (1217059006); Calcification of pineal gland (1217059006)
 
HPO: HP:0012682

Definition

Accumulation of calcium salts in the pineal gland. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineal gland calcification

Professional guidelines

PubMed

Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness.
Moon E, Kim K, Partonen T, Linnaranta O
Curr Psychiatry Rep 2022 Nov;24(11):623-634. Epub 2022 Oct 13 doi: 10.1007/s11920-022-01369-6. PMID: 36227449Free PMC Article
Exploratory assessment of pineal gland volume, composition, and urinary 6-sulfatoxymelatonin levels on prostate cancer risk.
Bazzi LA, Sigurdardottir LG, Sigurdsson S, Valdimarsdottir U, Torfadottir J, Aspelund T, Czeisler CA, Lockley SW, Jonsson E, Launer L, Harris T, Gudnason V, Mucci LA, Markt SC
Prostate 2021 Jun;81(8):487-496. Epub 2021 Apr 16 doi: 10.1002/pros.24130. PMID: 33860950Free PMC Article
Pineal region masses: differential diagnosis.
Smirniotopoulos JG, Rushing EJ, Mena H
Radiographics 1992 May;12(3):577-96. doi: 10.1148/radiographics.12.3.1609147. PMID: 1609147

Recent clinical studies

Etiology

Prevalence of pineal gland calcification: systematic review and meta-analysis.
Belay DG, Worku MG
Syst Rev 2023 Mar 6;12(1):32. doi: 10.1186/s13643-023-02205-5. PMID: 36879256Free PMC Article
Cross-sectional analysis of potential risk factors of the pineal gland calcification.
Jalali N, Firouzabadi MD, Mirshekar A, Khalili P, Ravangard AR, Ahmadi J, Askari PS, Jalali Z
BMC Endocr Disord 2023 Feb 28;23(1):49. doi: 10.1186/s12902-023-01301-w. PMID: 36855104Free PMC Article
Pineal Gland Calcification in Kurdistan: A Cross-Sectional Study of 480 Roentgenograms.
Mohammed KA, Adjei Boakye E, Ismail HA, Geneus CJ, Tobo BB, Buchanan PM, Zelicoff AP
PLoS One 2016;11(7):e0159239. Epub 2016 Jul 14 doi: 10.1371/journal.pone.0159239. PMID: 27415622Free PMC Article
Is there a correlation between the pineal gland calcification and migraine?
Ozlece HK, Akyuz O, Ilik F, Huseyinoglu N, Aydin S, Can S, Serim VA
Eur Rev Med Pharmacol Sci 2015 Oct;19(20):3861-4. PMID: 26531271
Stroke and pineal gland calcification: lack of association. Results from a population-based study (The Atahualpa Project).
Del Brutto OH, Mera RM, Lama J, Zambrano M
Clin Neurol Neurosurg 2015 Mar;130:91-4. Epub 2015 Jan 5 doi: 10.1016/j.clineuro.2014.12.019. PMID: 25594846

Diagnosis

Diagnostic accuracy of susceptibility-weighted magnetic resonance imaging for the evaluation of pineal gland calcification.
Adams LC, Böker SM, Bender YY, Diederichs G, Fallenberg EM, Wagner M, Hamm B, Makowski MR
PLoS One 2017;12(3):e0172764. Epub 2017 Mar 9 doi: 10.1371/journal.pone.0172764. PMID: 28278291Free PMC Article
Is there a correlation between the pineal gland calcification and migraine?
Ozlece HK, Akyuz O, Ilik F, Huseyinoglu N, Aydin S, Can S, Serim VA
Eur Rev Med Pharmacol Sci 2015 Oct;19(20):3861-4. PMID: 26531271
Stroke and pineal gland calcification: lack of association. Results from a population-based study (The Atahualpa Project).
Del Brutto OH, Mera RM, Lama J, Zambrano M
Clin Neurol Neurosurg 2015 Mar;130:91-4. Epub 2015 Jan 5 doi: 10.1016/j.clineuro.2014.12.019. PMID: 25594846
Pineal gland calcification.
Pillai KM
Neurol India 1968 Jan-Mar;16(1):35-6. PMID: 5681716
The tentorial pressure cone, its significance and its diagnosis through dislocation of the calcified pineal body.
LILJA B
Acta Radiol (Stockh) 1948 Aug 31;30(1-2):129-51. doi: 10.3109/00016924809177159. PMID: 18887632

Prognosis

Pineal Gland Calcification in Kurdistan: A Cross-Sectional Study of 480 Roentgenograms.
Mohammed KA, Adjei Boakye E, Ismail HA, Geneus CJ, Tobo BB, Buchanan PM, Zelicoff AP
PLoS One 2016;11(7):e0159239. Epub 2016 Jul 14 doi: 10.1371/journal.pone.0159239. PMID: 27415622Free PMC Article
Incidence of normal pineal and chroids plexus calcification on brain CT (computerized tomography) at Tikur Anbessa Teaching Hospital Addis Ababa, Ethiopia.
Admassie D, Mekonnen A
Ethiop Med J 2009 Jan;47(1):55-60. PMID: 19743781
Computed tomography study of pineal calcification in schizophrenia.
Bersani G, Garavini A, Taddei I, Tanfani G, Nordio M, Pancheri P
Eur Psychiatry 1999 Jun;14(3):163-6. doi: 10.1016/s0924-9338(99)80735-4. PMID: 10572342

Clinical prediction guides

Cross-sectional analysis of potential risk factors of the pineal gland calcification.
Jalali N, Firouzabadi MD, Mirshekar A, Khalili P, Ravangard AR, Ahmadi J, Askari PS, Jalali Z
BMC Endocr Disord 2023 Feb 28;23(1):49. doi: 10.1186/s12902-023-01301-w. PMID: 36855104Free PMC Article
Micromorphology of pineal gland calcification in age-related neurodegenerative diseases.
Bukreeva I, Junemann O, Cedola A, Brun F, Longo E, Tromba G, Wilde F, Chukalina MV, Krivonosov YS, Dyachkova IG, Buzmakov AV, Zolotov DA, Palermo F, Gigli G, Otlyga DA, Saveliev SV, Fratini M, Asadchikov VE
Med Phys 2023 Mar;50(3):1601-1613. Epub 2022 Nov 26 doi: 10.1002/mp.16080. PMID: 36309985
Computed tomography study of pineal calcification in schizophrenia.
Bersani G, Garavini A, Taddei I, Tanfani G, Nordio M, Pancheri P
Eur Psychiatry 1999 Jun;14(3):163-6. doi: 10.1016/s0924-9338(99)80735-4. PMID: 10572342
Pineal gland calcification and defective sense of direction.
Bayliss CR, Bishop NL, Fowler RC
Br Med J (Clin Res Ed) 1985 Dec 21-28;291(6511):1758-9. doi: 10.1136/bmj.291.6511.1758. PMID: 3936572Free PMC Article

Recent systematic reviews

Prevalence of pineal gland calcification: systematic review and meta-analysis.
Belay DG, Worku MG
Syst Rev 2023 Mar 6;12(1):32. doi: 10.1186/s13643-023-02205-5. PMID: 36879256Free PMC Article

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