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Ampullary Noninvasive Papillary Neoplasm, Pancreatobiliary Type

MedGen UID:
474066
•Concept ID:
C3272433
•
Neoplastic Process
Synonym: Noninvasive Papillary Neoplasm, Pancreatobiliary Type

Definition

An exophytic, preinvasive, papillary epithelial neoplasm that arises from the ampulla of Vater. Histologically it resembles the papillary neoplasms of the biliary tree. This category includes neoplasms with low grade dysplasia and high grade dysplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpullary Noninvasive Papillary Neoplasm, Pancreatobiliary Type

Professional guidelines

PubMed

Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting.
Adsay V, Mino-Kenudson M, Furukawa T, Basturk O, Zamboni G, Marchegiani G, Bassi C, Salvia R, Malleo G, Paiella S, Wolfgang CL, Matthaei H, Offerhaus GJ, Adham M, Bruno MJ, Reid MD, Krasinskas A, Klöppel G, Ohike N, Tajiri T, Jang KT, Roa JC, Allen P, Fernández-del Castillo C, Jang JY, Klimstra DS, Hruban RH; Members of Verona Consensus Meeting, 2013
Ann Surg 2016 Jan;263(1):162-77. doi: 10.1097/SLA.0000000000001173. PMID: 25775066Free PMC Article

Recent clinical studies

Etiology

Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting.
Adsay V, Mino-Kenudson M, Furukawa T, Basturk O, Zamboni G, Marchegiani G, Bassi C, Salvia R, Malleo G, Paiella S, Wolfgang CL, Matthaei H, Offerhaus GJ, Adham M, Bruno MJ, Reid MD, Krasinskas A, Klöppel G, Ohike N, Tajiri T, Jang KT, Roa JC, Allen P, Fernández-del Castillo C, Jang JY, Klimstra DS, Hruban RH; Members of Verona Consensus Meeting, 2013
Ann Surg 2016 Jan;263(1):162-77. doi: 10.1097/SLA.0000000000001173. PMID: 25775066Free PMC Article
Comparison between the location and the histomorphological/immunohistochemical characteristics of noninvasive neoplasms of the ampulla of Vater.
Yamamoto Y, Nemoto T, Okubo Y, Nihonyanagi Y, Ishiwatari T, Takuma K, Tochigi N, Okano N, Wakayama M, Igarashi Y, Shibuya K
Hum Pathol 2014 Sep;45(9):1910-7. Epub 2014 Jun 12 doi: 10.1016/j.humpath.2014.05.013. PMID: 25081540

Diagnosis

Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting.
Adsay V, Mino-Kenudson M, Furukawa T, Basturk O, Zamboni G, Marchegiani G, Bassi C, Salvia R, Malleo G, Paiella S, Wolfgang CL, Matthaei H, Offerhaus GJ, Adham M, Bruno MJ, Reid MD, Krasinskas A, Klöppel G, Ohike N, Tajiri T, Jang KT, Roa JC, Allen P, Fernández-del Castillo C, Jang JY, Klimstra DS, Hruban RH; Members of Verona Consensus Meeting, 2013
Ann Surg 2016 Jan;263(1):162-77. doi: 10.1097/SLA.0000000000001173. PMID: 25775066Free PMC Article
Intra-ampullary papillary-tubular neoplasm (IAPN): characterization of tumoral intraepithelial neoplasia occurring within the ampulla: a clinicopathologic analysis of 82 cases.
Ohike N, Kim GE, Tajiri T, Krasinskas A, Basturk O, Coban I, Bandyopadhyay S, Morohoshi T, Goodman M, Kooby DA, Sarmiento JM, Adsay NV
Am J Surg Pathol 2010 Dec;34(12):1731-48. doi: 10.1097/PAS.0b013e3181f8ff05. PMID: 21084962Free PMC Article

Prognosis

Intra-ampullary papillary-tubular neoplasm (IAPN): characterization of tumoral intraepithelial neoplasia occurring within the ampulla: a clinicopathologic analysis of 82 cases.
Ohike N, Kim GE, Tajiri T, Krasinskas A, Basturk O, Coban I, Bandyopadhyay S, Morohoshi T, Goodman M, Kooby DA, Sarmiento JM, Adsay NV
Am J Surg Pathol 2010 Dec;34(12):1731-48. doi: 10.1097/PAS.0b013e3181f8ff05. PMID: 21084962Free PMC Article

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