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Gallbladder Cribriform Carcinoma

MedGen UID:
474736
•Concept ID:
C3273103
•
Neoplastic Process

Definition

A rare variant of gallbladder adenocarcinoma. It is characterized by the presence of a malignant glandular epithelial infiltrate with a cribriform growth pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Cribriform Carcinoma

Professional guidelines

PubMed

Biliary tract cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Vogel A, Bridgewater J, Edeline J, Kelley RK, Klümpen HJ, Malka D, Primrose JN, Rimassa L, Stenzinger A, Valle JW, Ducreux M; ESMO Guidelines Committee. Electronic address: [email protected]
Ann Oncol 2023 Feb;34(2):127-140. Epub 2022 Nov 10 doi: 10.1016/j.annonc.2022.10.506. PMID: 36372281
Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
J Natl Compr Canc Netw 2021 May 1;19(5):541-565. doi: 10.6004/jnccn.2021.0022. PMID: 34030131
Gallbladder adenomyomatosis: Diagnosis and management.
Golse N, Lewin M, Rode A, Sebagh M, Mabrut JY
J Visc Surg 2017 Oct;154(5):345-353. Epub 2017 Aug 24 doi: 10.1016/j.jviscsurg.2017.06.004. PMID: 28844704

Recent clinical studies

Etiology

Survival benefit of adjuvant chemotherapy in patients with resected gallbladder adenocarcinoma: An updated retrospective cohort analysis.
Wang Y, Kong Y, Yang Q, Zhong C, Zhou D, Wang W
Eur J Surg Oncol 2024 Apr;50(4):108047. Epub 2024 Feb 21 doi: 10.1016/j.ejso.2024.108047. PMID: 38401352
Treatment Modality and Trends in Survival for Gallbladder Cancer: a Population-Based Study.
Akhtar-Danesh N, Akhtar-Danseh GG, Seow H, Shakeel S, Finley C
J Gastrointest Cancer 2021 Mar;52(1):256-262. doi: 10.1007/s12029-020-00397-w. PMID: 32185744
Incidence and significance of GATA3 positivity in gallbladder adenocarcinoma.
Guo W, Lee W, Lu Y, Li X, Chandan VS
Hum Pathol 2020 Dec;106:39-44. Epub 2020 Sep 28 doi: 10.1016/j.humpath.2020.09.012. PMID: 32991930
Porcelain gallbladder.
Ansari S
Indian J Gastroenterol 2014 Jul;33(4):399. doi: 10.1007/s12664-013-0362-x. PMID: 23982704
Cystic duct patency in malignant obstructive jaundice. An ERCP-based study relevant to the role of laparoscopic cholecystojejunostomy.
Tarnasky PR, England RE, Lail LM, Pappas TN, Cotton PB
Ann Surg 1995 Mar;221(3):265-71. doi: 10.1097/00000658-199503000-00008. PMID: 7536405Free PMC Article

Diagnosis

An unusual lesion of the gallbladder mimicking gallbladder carcinoma.
Yang L, Hu C, Ma D, Yu Z
Dig Liver Dis 2022 Sep;54(9):1266. Epub 2021 Jul 20 doi: 10.1016/j.dld.2021.07.001. PMID: 34294579
Neuroendocrine Carcinoma of the Gallbladder.
Sharma A, Saluja SS, Nag HH, Sharma M, Sakhuja P
Am Surg 2022 Nov;88(11):2768-2770. Epub 2020 Sep 16 doi: 10.1177/0003134820951466. PMID: 32935998
Novel cholangioscopy-guided targeted biopsy for diagnosing gallbladder carcinoma.
Kobayashi K, Kobara H, Masaki T
Dig Endosc 2021 May;33(4):e51-e53. Epub 2021 Jan 28 doi: 10.1111/den.13925. PMID: 33506562
Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases.
Adsay V, Jang KT, Roa JC, Dursun N, Ohike N, Bagci P, Basturk O, Bandyopadhyay S, Cheng JD, Sarmiento JM, Escalona OT, Goodman M, Kong SY, Terry P
Am J Surg Pathol 2012 Sep;36(9):1279-301. doi: 10.1097/PAS.0b013e318262787c. PMID: 22895264
Tumours of the gallbladder.
Bevan G
Clin Gastroenterol 1973 Jan;2(1):175-84. PMID: 4588236

Therapy

Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
J Natl Compr Canc Netw 2021 May 1;19(5):541-565. doi: 10.6004/jnccn.2021.0022. PMID: 34030131
Cholangiocarcinoma.
Squadroni M, Tondulli L, Gatta G, Mosconi S, Beretta G, Labianca R
Crit Rev Oncol Hematol 2017 Aug;116:11-31. Epub 2016 Nov 25 doi: 10.1016/j.critrevonc.2016.11.012. PMID: 28693792
SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma.
Ben-Josef E, Guthrie KA, El-Khoueiry AB, Corless CL, Zalupski MM, Lowy AM, Thomas CR Jr, Alberts SR, Dawson LA, Micetich KC, Thomas MB, Siegel AB, Blanke CD
J Clin Oncol 2015 Aug 20;33(24):2617-22. Epub 2015 May 11 doi: 10.1200/JCO.2014.60.2219. PMID: 25964250Free PMC Article
Hemobilia.
Bismuth H
N Engl J Med 1973 Mar 22;288(12):617-9. doi: 10.1056/NEJM197303222881207. PMID: 4346967
Abdominal surgery.
Welch CE
N Engl J Med 1969 Feb 20;280(8):419-25 contd. doi: 10.1056/NEJM196902202800805. PMID: 4883944

Prognosis

Carcinosarcoma of the gallbladder diagnosed in a cholecystectomy specimen.
Paricio JJ, Serrano Egea A, Mariscal Zabala S, Verdú Martín E, Sánchez Díaz E
Rev Esp Enferm Dig 2022 Jan;114(1):55-56. doi: 10.17235/reed.2021.8136/2021. PMID: 34139854
Treatment Modality and Trends in Survival for Gallbladder Cancer: a Population-Based Study.
Akhtar-Danesh N, Akhtar-Danseh GG, Seow H, Shakeel S, Finley C
J Gastrointest Cancer 2021 Mar;52(1):256-262. doi: 10.1007/s12029-020-00397-w. PMID: 32185744
Incidence and significance of GATA3 positivity in gallbladder adenocarcinoma.
Guo W, Lee W, Lu Y, Li X, Chandan VS
Hum Pathol 2020 Dec;106:39-44. Epub 2020 Sep 28 doi: 10.1016/j.humpath.2020.09.012. PMID: 32991930
Traditional serrated adenomas of the upper digestive tract.
Rubio CA
J Clin Pathol 2016 Jan;69(1):1-5. Epub 2015 Oct 14 doi: 10.1136/jclinpath-2015-203258. PMID: 26468393Free PMC Article
Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases.
Adsay V, Jang KT, Roa JC, Dursun N, Ohike N, Bagci P, Basturk O, Bandyopadhyay S, Cheng JD, Sarmiento JM, Escalona OT, Goodman M, Kong SY, Terry P
Am J Surg Pathol 2012 Sep;36(9):1279-301. doi: 10.1097/PAS.0b013e318262787c. PMID: 22895264

Clinical prediction guides

Survival benefit of adjuvant chemotherapy in patients with resected gallbladder adenocarcinoma: An updated retrospective cohort analysis.
Wang Y, Kong Y, Yang Q, Zhong C, Zhou D, Wang W
Eur J Surg Oncol 2024 Apr;50(4):108047. Epub 2024 Feb 21 doi: 10.1016/j.ejso.2024.108047. PMID: 38401352
High intramuscular adipose tissue content associated with prognosis and postoperative complications of cancers.
Liu R, Qiu Z, Zhang L, Ma W, Zi L, Wang K, Kuang T, Zhao K, Wang W
J Cachexia Sarcopenia Muscle 2023 Dec;14(6):2509-2519. Epub 2023 Nov 22 doi: 10.1002/jcsm.13371. PMID: 37990969Free PMC Article
Current and emerging therapies for advanced biliary tract cancers.
Kam AE, Masood A, Shroff RT
Lancet Gastroenterol Hepatol 2021 Nov;6(11):956-969. doi: 10.1016/S2468-1253(21)00171-0. PMID: 34626563
Treatment Modality and Trends in Survival for Gallbladder Cancer: a Population-Based Study.
Akhtar-Danesh N, Akhtar-Danseh GG, Seow H, Shakeel S, Finley C
J Gastrointest Cancer 2021 Mar;52(1):256-262. doi: 10.1007/s12029-020-00397-w. PMID: 32185744
Incidence and significance of GATA3 positivity in gallbladder adenocarcinoma.
Guo W, Lee W, Lu Y, Li X, Chandan VS
Hum Pathol 2020 Dec;106:39-44. Epub 2020 Sep 28 doi: 10.1016/j.humpath.2020.09.012. PMID: 32991930

Recent systematic reviews

High intramuscular adipose tissue content associated with prognosis and postoperative complications of cancers.
Liu R, Qiu Z, Zhang L, Ma W, Zi L, Wang K, Kuang T, Zhao K, Wang W
J Cachexia Sarcopenia Muscle 2023 Dec;14(6):2509-2519. Epub 2023 Nov 22 doi: 10.1002/jcsm.13371. PMID: 37990969Free PMC Article
Systematic review of squamous cell carcinoma of the gallbladder.
Takahashi H, Irri A, Fenig Y, Byale A, Thung S, Gunasekaran G
Am J Surg 2022 Sep;224(3):863-868. Epub 2022 Apr 23 doi: 10.1016/j.amjsurg.2022.04.024. PMID: 35483997
Prognostic significance of tumor budding in biliary tract cancer.
Regmi P, Paudyal A, Paudyal P, Hu HJ, Liu F, Ma WJ, Jin YW, Li FY
Eur J Surg Oncol 2022 Jan;48(1):160-168. Epub 2021 Aug 13 doi: 10.1016/j.ejso.2021.08.008. PMID: 34412954
Adiposity and cancer at major anatomical sites: umbrella review of the literature.
Kyrgiou M, Kalliala I, Markozannes G, Gunter MJ, Paraskevaidis E, Gabra H, Martin-Hirsch P, Tsilidis KK
BMJ 2017 Feb 28;356:j477. doi: 10.1136/bmj.j477. PMID: 28246088Free PMC Article
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M
Lancet 2008 Feb 16;371(9612):569-78. doi: 10.1016/S0140-6736(08)60269-X. PMID: 18280327

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