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Abnormal glomerular filtration rate

MedGen UID:: 489765
•Concept ID:: C0854050
•: Finding

Synonym:	Abnormal GFR

HPO:	HP:0012212

Definition

An abnormally increased or reduced amount of fluid filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal glomerular filtration rate

Fetal anomaly
- Congenital Systemic Disorder
  - Abnormality of the genitourinary system
    - Abnormality of the urinary system
      - Abnormality of the urinary system physiology
        Abnormal renal physiology
        Abnormal glomerular filtration rate
        Decreased glomerular filtration rate
        Increased glomerular filtration rate

Professional guidelines

PubMed

Assessment of kidney function and associated risk factors among type 2 diabetic patients.

Jamal Shahwan M, Hassan NAG, Shaheen RA
Diabetes Metab Syndr 2019 Jul-Aug;13(4):2661-2665. Epub 2019 Jul 11 doi: 10.1016/j.dsx.2019.07.025. PMID: 31405691

Evaluation of the National Kidney Foundation of Hawai'i's Kidney Early Detection Screening program.

Kataoka-Yahiro MR, Wong KA, Tamashiro J, Page V, Ching J, Li D
Hawaii J Med Public Health 2012 Jul;71(7):186-92. PMID: 22787570 Free PMC Article

See all (2)

Recent clinical studies

Etiology

What every clinician needs to know about chronic kidney disease: Detection, classification and epidemiology.

Selby NM, Taal MW
Diabetes Obes Metab 2024 Nov;26 Suppl 6:3-12. Epub 2024 May 28 doi: 10.1111/dom.15683. PMID: 38804058

Longitudinal assessment of renal function in native kidney after bariatric surgery.

Favre G, Schiavo L, Lemoine S, Esnault VLM, Iannelli A
Surg Obes Relat Dis 2018 Sep;14(9):1411-1418. Epub 2018 May 24 doi: 10.1016/j.soard.2018.05.013. PMID: 30077663

Persistently elevated parathyroid hormone after successful parathyroid surgery.

Duke WS, Kim AS, Waller JL, Terris DJ
Laryngoscope 2017 Jul;127(7):1720-1723. Epub 2016 Aug 22 doi: 10.1002/lary.26205. PMID: 27545973

Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia.

Schaefer BA, Flanagan JM, Alvarez OA, Nelson SC, Aygun B, Nottage KA, George A, Roberts CW, Piccone CM, Howard TA, Davis BR, Ware RE
PLoS One 2016;11(10):e0164364. Epub 2016 Oct 6 doi: 10.1371/journal.pone.0164364. PMID: 27711207 Free PMC Article

Long-term outcome of meningococcal sepsis-associated acute renal failure.

Slack R, Hawkins KC, Gilhooley L, Addison GM, Lewis MA, Webb NJ
Pediatr Crit Care Med 2005 Jul;6(4):477-9. doi: 10.1097/01.PCC.0000163285.74452.23. PMID: 15982443

See all (13)

Diagnosis

Clinicopathological Pattern of Renal Biopsies in Children with Nephrotic Syndrome.

Kumar A, Narayan M, Kumari S
Clin Med Res 2024 Jun;22(2):76-83. doi: 10.3121/cmr.2024.1917. PMID: 39231623 Free PMC Article

What every clinician needs to know about chronic kidney disease: Detection, classification and epidemiology.

Selby NM, Taal MW
Diabetes Obes Metab 2024 Nov;26 Suppl 6:3-12. Epub 2024 May 28 doi: 10.1111/dom.15683. PMID: 38804058

Podocyte injury of diabetic nephropathy: Novel mechanism discovery and therapeutic prospects.

Li X, Zhang Y, Xing X, Li M, Liu Y, Xu A, Zhang J
Biomed Pharmacother 2023 Dec;168:115670. Epub 2023 Oct 13 doi: 10.1016/j.biopha.2023.115670. PMID: 37837883

Persistently elevated parathyroid hormone after successful parathyroid surgery.

Duke WS, Kim AS, Waller JL, Terris DJ
Laryngoscope 2017 Jul;127(7):1720-1723. Epub 2016 Aug 22 doi: 10.1002/lary.26205. PMID: 27545973

Abnormal glomerular filtration rate in children, adolescents and young adults starts below 75 mL/min/1.73 m(2).

Pottel H, Hoste L, Delanaye P
Pediatr Nephrol 2015 May;30(5):821-8. Epub 2014 Nov 19 doi: 10.1007/s00467-014-3002-5. PMID: 25403744

See all (9)

Therapy

Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia.

Biventricular Berlin Heart EXCOR pediatric use across the united states.

Zafar F, Jefferies JL, Tjossem CJ, Bryant R 3rd, Jaquiss RD, Wearden PD, Rosenthal DN, Cabrera AG, Rossano JW, Humpl T, Morales DL
Ann Thorac Surg 2015 Apr;99(4):1328-34. Epub 2015 Feb 20 doi: 10.1016/j.athoracsur.2014.09.078. PMID: 25704863

Cancer and renal insufficiency results of the BIRMA study.

Janus N, Launay-Vacher V, Byloos E, Machiels JP, Duck L, Kerger J, Wynendaele W, Canon JL, Lybaert W, Nortier J, Deray G, Wildiers H
Br J Cancer 2010 Dec 7;103(12):1815-21. Epub 2010 Nov 9 doi: 10.1038/sj.bjc.6605979. PMID: 21063408 Free PMC Article

Progression of chronic renal failure.

Yu HT
Arch Intern Med 2003 Jun 23;163(12):1417-29. doi: 10.1001/archinte.163.12.1417. PMID: 12824091

Tyrosinemia: the Quebec experience.

Paradis K
Clin Invest Med 1996 Oct;19(5):311-6. PMID: 8889268

See all (7)

Prognosis

What every clinician needs to know about chronic kidney disease: Detection, classification and epidemiology.

Selby NM, Taal MW
Diabetes Obes Metab 2024 Nov;26 Suppl 6:3-12. Epub 2024 May 28 doi: 10.1111/dom.15683. PMID: 38804058

Longitudinal assessment of renal function in native kidney after bariatric surgery.

Favre G, Schiavo L, Lemoine S, Esnault VLM, Iannelli A
Surg Obes Relat Dis 2018 Sep;14(9):1411-1418. Epub 2018 May 24 doi: 10.1016/j.soard.2018.05.013. PMID: 30077663

Functional principal component analysis of glomerular filtration rate curves after kidney transplant.

Dong JJ, Wang L, Gill J, Cao J
Stat Methods Med Res 2018 Dec;27(12):3785-3796. Epub 2017 Jun 20 doi: 10.1177/0962280217712088. PMID: 28633602

Biventricular Berlin Heart EXCOR pediatric use across the united states.

Long-term outcome of meningococcal sepsis-associated acute renal failure.

Slack R, Hawkins KC, Gilhooley L, Addison GM, Lewis MA, Webb NJ
Pediatr Crit Care Med 2005 Jul;6(4):477-9. doi: 10.1097/01.PCC.0000163285.74452.23. PMID: 15982443

See all (9)

Clinical prediction guides

Longitudinal assessment of renal function in native kidney after bariatric surgery.

Favre G, Schiavo L, Lemoine S, Esnault VLM, Iannelli A
Surg Obes Relat Dis 2018 Sep;14(9):1411-1418. Epub 2018 May 24 doi: 10.1016/j.soard.2018.05.013. PMID: 30077663

Functional principal component analysis of glomerular filtration rate curves after kidney transplant.

Dong JJ, Wang L, Gill J, Cao J
Stat Methods Med Res 2018 Dec;27(12):3785-3796. Epub 2017 Jun 20 doi: 10.1177/0962280217712088. PMID: 28633602

Biventricular Berlin Heart EXCOR pediatric use across the united states.

Long-term follow-up evaluation of renal function in patients treated with peritoneal dialysis after cardiac surgery for correction of congenital anomalies.

Mel E, Davidovits M, Dagan O
J Thorac Cardiovasc Surg 2014 Jan;147(1):451-5. Epub 2013 Apr 30 doi: 10.1016/j.jtcvs.2013.03.032. PMID: 23639428

Tyrosinemia: the Quebec experience.

Paradis K
Clin Invest Med 1996 Oct;19(5):311-6. PMID: 8889268

See all (7)