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Tarsal tunnel syndrome

MedGen UID:
52646
•Concept ID:
C0039319
•
Disease or Syndrome
Synonyms: Neuropathy of the posterior tibial nerve and its branches; Posterior Tibial Nerve Neuralgia
SNOMED CT: TTS - Tarsal tunnel syndrome (47374004); Tarsal tunnel syndrome (ankle condition) (47374004); Tarsal tunnel syndrome (47374004)
 
Monarch Initiative: MONDO:0006994

Definition

A syndrome resulting from the entrapment and compression of the tibial nerve. Signs and symptoms include burning sensation, tingling, and pain in the foot sole. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTarsal tunnel syndrome

Professional guidelines

PubMed

Rearfoot disorders and conservative treatment: a narrative review.
Choo YJ, Park CH, Chang MC
Ann Palliat Med 2020 Sep;9(5):3546-3552. Epub 2020 Aug 6 doi: 10.21037/apm-20-446. PMID: 32787369
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Ultrasound in tarsal tunnel syndrome: Correct diagnosis for appropriate treatment.
Coraci D, Ioppolo F, Di Sante L, Santilli V, Padua L
Muscle Nerve 2016 Dec;54(6):1148-1149. Epub 2016 Oct 18 doi: 10.1002/mus.25399. PMID: 27610548

Recent clinical studies

Etiology

Ganglia-Induced Tarsal Tunnel Syndrome.
Koketsu K, Kim K, Tajiri T, Isu T, Morimoto D, Kokubo R, Dan H, Morita A
J Nippon Med Sch 2024;91(1):114-118. doi: 10.1272/jnms.JNMS.2024_91-203. PMID: 38462440
Predictive factors of effective tibial nerve release in tarsal tunnel syndrome.
Bouysset M, Denarié D, Coillard JY, Boublil D, Lalevée M, Tavernier T, Fantino O, Lefebvre T, Damiano J, Confavreux CB, Tebib JG, Coury F
Foot Ankle Surg 2022 Jul;28(5):610-615. Epub 2021 Jul 3 doi: 10.1016/j.fas.2021.06.009. PMID: 34246562
Clinico-radiological review of peripheral entrapment neuropathies - Part 2 Lower limb.
Manoharan D, Sudhakaran D, Goyal A, Srivastava DN, Ansari MT
Eur J Radiol 2021 Feb;135:109482. Epub 2020 Dec 17 doi: 10.1016/j.ejrad.2020.109482. PMID: 33360825
Anterior tarsal tunnel syndrome: a misunderstood and a misleading entrapment neuropathy.
Logullo F, Ganino C, Lupidi F, Perozzi C, Di Bella P, Provinciali L
Neurol Sci 2014 May;35(5):773-5. Epub 2013 Dec 12 doi: 10.1007/s10072-013-1601-8. PMID: 24337947
Diagnosis and treatment of chronic ankle pain.
Wukich DK, Tuason DA
Instr Course Lect 2011;60:335-50. PMID: 21553785

Diagnosis

Tarsal Tunnel Syndrome.
Nelson SC
Clin Podiatr Med Surg 2021 Apr;38(2):131-141. doi: 10.1016/j.cpm.2020.12.001. PMID: 33745647
Lower extremity entrapment neuropathies.
Madani S, Doughty C
Best Pract Res Clin Rheumatol 2020 Jun;34(3):101565. Epub 2020 Jul 31 doi: 10.1016/j.berh.2020.101565. PMID: 32747188
Entrapment Neuropathies of the Lower Extremity.
Bowley MP, Doughty CT
Med Clin North Am 2019 Mar;103(2):371-382. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.013. PMID: 30704688
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Tarsal tunnel syndrome.
Gould JS
Foot Ankle Clin 2011 Jun;16(2):275-86. doi: 10.1016/j.fcl.2011.01.008. PMID: 21600447

Therapy

Managing the patient with heel pain.
Bhatty UN, Khan SH, Zubairy AI
Br J Hosp Med (Lond) 2019 Apr 2;80(4):196-200. doi: 10.12968/hmed.2019.80.4.196. PMID: 30951414
Considerations in footwear and orthotics.
Khan MN, Jacobs BC, Ashbaugh S
Prim Care 2013 Dec;40(4):1001-12, x. Epub 2013 Oct 15 doi: 10.1016/j.pop.2013.08.013. PMID: 24209730
Tarsal tunnel syndrome.
Broadhurst N
Aust Fam Physician 1995 Apr;24(4):654-5. PMID: 7771975
Tarsal tunnel syndrome.
Mann RA
Orthop Clin North Am 1974 Jan;5(1):109-15. PMID: 4149033
Burning feet.
Br Med J 1972 Jul 22;3(5820):193. PMID: 5040704Free PMC Article

Prognosis

Predictive factors of effective tibial nerve release in tarsal tunnel syndrome.
Bouysset M, Denarié D, Coillard JY, Boublil D, Lalevée M, Tavernier T, Fantino O, Lefebvre T, Damiano J, Confavreux CB, Tebib JG, Coury F
Foot Ankle Surg 2022 Jul;28(5):610-615. Epub 2021 Jul 3 doi: 10.1016/j.fas.2021.06.009. PMID: 34246562
Ultrasound Imaging of the Deep Peroneal Nerve.
Becciolini M, Pivec C, Riegler G
J Ultrasound Med 2021 Apr;40(4):821-838. Epub 2020 Sep 3 doi: 10.1002/jum.15455. PMID: 32881065
Tarsal tunnel syndrome: A literature review.
Ahmad M, Tsang K, Mackenney PJ, Adedapo AO
Foot Ankle Surg 2012 Sep;18(3):149-52. Epub 2011 Dec 21 doi: 10.1016/j.fas.2011.10.007. PMID: 22857954
Peripheral nerve entrapments.
Hirose CB, McGarvey WC
Foot Ankle Clin 2004 Jun;9(2):255-69. doi: 10.1016/j.fcl.2004.02.001. PMID: 15165581
The foot in sport.
Sherman KP
Br J Sports Med 1999 Feb;33(1):6-13. doi: 10.1136/bjsm.33.1.6. PMID: 10027050Free PMC Article

Clinical prediction guides

Ganglia-Induced Tarsal Tunnel Syndrome.
Koketsu K, Kim K, Tajiri T, Isu T, Morimoto D, Kokubo R, Dan H, Morita A
J Nippon Med Sch 2024;91(1):114-118. doi: 10.1272/jnms.JNMS.2024_91-203. PMID: 38462440
The bifurcation and topography of the posterior tibial artery within the tarsal tunnel.
Marchese B, McDonald A, McGowan H
Surg Radiol Anat 2023 May;45(5):611-622. Epub 2023 Mar 13 doi: 10.1007/s00276-023-03115-w. PMID: 36912942Free PMC Article
Patient Satisfaction with Surgery for Tarsal- and Carpal- Tunnel Syndrome - Comparative Study.
Kokubo R, Kim K, Isu T, Morimoto D, Morita A
Neurol Med Chir (Tokyo) 2023 Mar 15;63(3):116-121. Epub 2023 Jan 20 doi: 10.2176/jns-nmc.2022-0245. PMID: 36682791Free PMC Article
Predictive factors of effective tibial nerve release in tarsal tunnel syndrome.
Bouysset M, Denarié D, Coillard JY, Boublil D, Lalevée M, Tavernier T, Fantino O, Lefebvre T, Damiano J, Confavreux CB, Tebib JG, Coury F
Foot Ankle Surg 2022 Jul;28(5):610-615. Epub 2021 Jul 3 doi: 10.1016/j.fas.2021.06.009. PMID: 34246562
Tarsal tunnel syndrome: A literature review.
Ahmad M, Tsang K, Mackenney PJ, Adedapo AO
Foot Ankle Surg 2012 Sep;18(3):149-52. Epub 2011 Dec 21 doi: 10.1016/j.fas.2011.10.007. PMID: 22857954

Recent systematic reviews

Tarsal tunnel syndrome secondary to accessory or variant muscles: a clinical and anatomical systematic review.
Yammine K, Daher JC, Tannoury EH, Assi C
Surg Radiol Anat 2022 May;44(5):645-657. Epub 2022 Mar 30 doi: 10.1007/s00276-022-02932-9. PMID: 35353216
Anatomical characteristics of the flexor digitorum accessorius longus muscle and their relevance to tarsal tunnel syndrome a systematic review.
Deleu PA, Bevernage BD, Birch I, Maldague P, Gombault V, Leemrijse T
J Am Podiatr Med Assoc 2015 Jul;105(4):344-55. doi: 10.7547/13-084.1. PMID: 26218158
Outcomes and safety of endoscopic tarsal tunnel decompression: a systematic review.
Gkotsoulias EN, Simonson DC, Roukis TS
Foot Ankle Spec 2014 Feb;7(1):57-60. Epub 2013 Dec 10 doi: 10.1177/1938640013514267. PMID: 24334368
Neurologic involvement in scleroderma: a systematic review.
Amaral TN, Peres FA, Lapa AT, Marques-Neto JF, Appenzeller S
Semin Arthritis Rheum 2013 Dec;43(3):335-47. Epub 2013 Jul 1 doi: 10.1016/j.semarthrit.2013.05.002. PMID: 23827688

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