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Secondary hemochromatosis

MedGen UID:
536772
Concept ID:
C0238158
Disease or Syndrome
Synonym: Secondary Hemochromatosis
SNOMED CT: Secondary hemochromatosis (53836006)

Definition

Hemochromatosis that is not inherited and is caused by iron overload from excessive consumption, multiple transfusions, or disorders of erythropoiesis. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Becker S
J Infus Nurs 2020 Mar/Apr;43(2):65-69. doi: 10.1097/NAN.0000000000000358. PMID: 32106193
Gattermann N
Dtsch Arztebl Int 2009 Jul;106(30):499-504, I. Epub 2009 Jul 24 doi: 10.3238/arztebl.2009.0499. PMID: 19727383Free PMC Article
Blume KG, Beutler E, Chillar RK, Fahey JL, Sharkoff D, Zia PK
JAMA 1978 May 19;239(20):2149-51. PMID: 642157

Recent clinical studies

Etiology

van Vuren A, Kerkhoffs JL, Schols S, Rijneveld A, Nur E, Peereboom D, Gandon Y, Welsing P, van Wijk R, Schutgens R, van Solinge W, Marx J, Leiner T, Biemond B, van Beers E
Am J Hematol 2022 Jul;97(7):924-932. Epub 2022 May 10 doi: 10.1002/ajh.26581. PMID: 35472008Free PMC Article
Kernan KF, Carcillo JA
Int Immunol 2017 Nov 1;29(9):401-409. doi: 10.1093/intimm/dxx031. PMID: 28541437Free PMC Article
Gattermann N
Dtsch Arztebl Int 2009 Jul;106(30):499-504, I. Epub 2009 Jul 24 doi: 10.3238/arztebl.2009.0499. PMID: 19727383Free PMC Article
Alla V, Bonkovsky HL
Semin Liver Dis 2005 Nov;25(4):461-72. doi: 10.1055/s-2005-923317. PMID: 16315139
Marks PW, Mitus AJ
Am J Hematol 1996 Jan;51(1):55-63. doi: 10.1002/(SICI)1096-8652(199601)51:1<55::AID-AJH9>3.0.CO;2-6. PMID: 8571938

Diagnosis

Lazcano-Díaz EA, Chango-Azanza DX, Vásquez-Ortiz ZY, Rosales-Uvera SG, Chapa-Ibargüengoitia M, Orihuela-Sandoval C, Hernández-Reyes JP
Arch Cardiol Mex 2021;91(3):373-374. doi: 10.24875/ACM.20000411. PMID: 34310587Free PMC Article
Gao Y, Zhang B, Song Y, Li G, Bao Y, Jiang Y, Gao L, Chen G, Wang J
Acta Haematol 2018;139(3):168-170. Epub 2018 Mar 29 doi: 10.1159/000486948. PMID: 29597199
Whitington PF
Semin Liver Dis 2012 Nov;32(4):325-32. Epub 2013 Feb 8 doi: 10.1055/s-0032-1329901. PMID: 23397533
Fistarol SK, Itin PH
J Dtsch Dermatol Ges 2010 Mar;8(3):187-201; quiz 201-2. Epub 2009 Sep 24 doi: 10.1111/j.1610-0387.2009.07137.x. PMID: 19788584
Marks PW, Mitus AJ
Am J Hematol 1996 Jan;51(1):55-63. doi: 10.1002/(SICI)1096-8652(199601)51:1<55::AID-AJH9>3.0.CO;2-6. PMID: 8571938

Therapy

van Vuren A, Kerkhoffs JL, Schols S, Rijneveld A, Nur E, Peereboom D, Gandon Y, Welsing P, van Wijk R, Schutgens R, van Solinge W, Marx J, Leiner T, Biemond B, van Beers E
Am J Hematol 2022 Jul;97(7):924-932. Epub 2022 May 10 doi: 10.1002/ajh.26581. PMID: 35472008Free PMC Article
Oh CK, Moon Y
Nutrients 2019 May 10;11(5) doi: 10.3390/nu11051047. PMID: 31083351Free PMC Article
Lichtman SM, Attivissimo L, Goldman IS, Schuster MW, Buchbinder A
Am J Hematol 1999 Aug;61(4):262-4. doi: 10.1002/(sici)1096-8652(199908)61:4<262::aid-ajh7>3.0.co;2-b. PMID: 10440913
Swartz RD, Legault DJ
Am J Med 1996 Mar;100(3):308-12. doi: 10.1016/S0002-9343(97)89489-2. PMID: 8629676
Blume KG, Beutler E, Chillar RK, Fahey JL, Sharkoff D, Zia PK
JAMA 1978 May 19;239(20):2149-51. PMID: 642157

Prognosis

Cannas G, Poutrel S, Heiblig M, Labussière H, Larcher MV, Thomas X, Hot A
Ann Hematol 2023 Jul;102(7):1657-1667. Epub 2023 Jun 3 doi: 10.1007/s00277-023-05294-3. PMID: 37269388Free PMC Article
Kanaka S, Kawano Y, Yokomuro S, Ando F, Itokawa N, Hatori T, Matsumoto K, Zen Y, Miyashita M, Yoshida H
J Nippon Med Sch 2021 May 12;88(2):138-144. Epub 2020 Aug 1 doi: 10.1272/jnms.JNMS.2021_88-306. PMID: 32741904
Kernan KF, Carcillo JA
Int Immunol 2017 Nov 1;29(9):401-409. doi: 10.1093/intimm/dxx031. PMID: 28541437Free PMC Article
Kirking MH
Clin Pharm 1991 Oct;10(10):775-83. PMID: 1742962
Blume KG, Beutler E, Chillar RK, Fahey JL, Sharkoff D, Zia PK
JAMA 1978 May 19;239(20):2149-51. PMID: 642157

Clinical prediction guides

Manganas K, Delicou S, Xydaki A, Kourakli A, Evliati L, Vlachaki E, Klironomos E, Diamantidis M, Lafiatis I, Kattamis A, Koskinas J
Br J Haematol 2023 Sep;202(6):1192-1198. Epub 2023 Jul 12 doi: 10.1111/bjh.18970. PMID: 37438880
Kernan KF, Carcillo JA
Int Immunol 2017 Nov 1;29(9):401-409. doi: 10.1093/intimm/dxx031. PMID: 28541437Free PMC Article
Lichtman SM, Attivissimo L, Goldman IS, Schuster MW, Buchbinder A
Am J Hematol 1999 Aug;61(4):262-4. doi: 10.1002/(sici)1096-8652(199908)61:4<262::aid-ajh7>3.0.co;2-b. PMID: 10440913
Marks PW, Mitus AJ
Am J Hematol 1996 Jan;51(1):55-63. doi: 10.1002/(SICI)1096-8652(199601)51:1<55::AID-AJH9>3.0.CO;2-6. PMID: 8571938
Laeng H, Egger T, Roethlisberger C, Cottier H
Am J Pathol 1988 May;131(2):344-50. PMID: 3282446Free PMC Article

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