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Decreased systolic blood pressure

MedGen UID:
548506
•Concept ID:
C0277885
•
Finding
Synonyms: Decreased systolic arterial; Decreased systolic arterial pressure; Decreased systolic BP; Low systolic arterial; Low systolic arterial pressure; Low systolic arterial pulse pressure; Low Systolic Blood Pressure; Reduced systolic blood pressure; Systolic Hypotension
SNOMED CT: Low systolic arterial pressure (81010002); Decreased systolic arterial pressure (81010002); Low systolic arterial pulse pressure (81010002); Decreased systolic blood pressure (81010002); Decreased systolic arterial (81010002); Low systolic arterial (81010002)
 
HPO: HP:0500105

Definition

Abnormal decrease in systolic blood pressure. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased systolic blood pressure

Professional guidelines

PubMed

Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis.
Nazarzadeh M, Bidel Z, Canoy D, Copland E, Bennett DA, Dehghan A, Davey Smith G, Holman RR, Woodward M, Gupta A, Adler AI, Wamil M, Sattar N, Cushman WC, McManus RJ, Teo K, Davis BR, Chalmers J, Pepine CJ, Rahimi K; Blood Pressure Lowering Treatment Trialists' Collaboration
Lancet Diabetes Endocrinol 2022 Sep;10(9):645-654. Epub 2022 Jul 22 doi: 10.1016/S2213-8587(22)00172-3. PMID: 35878651Free PMC Article
Genetic Determinants and Genotype-Phenotype Correlations in Vietnamese Patients With Dilated Cardiomyopathy.
Nguyen TV, Tran Vu MT, Do TNP, Tran THN, Do TH, Nguyen TMH, Tran Huynh BN, Le LA, Nguyen Pham NT, Nguyen TDA, Nguyen TMN, Le NHP, Pham Nguyen V, Ho Huynh TD
Circ J 2021 Aug 25;85(9):1469-1478. Epub 2021 May 20 doi: 10.1253/circj.CJ-21-0077. PMID: 34011823
Changes in metabolic parameters and cardiovascular risk factors after therapeutic control of acromegaly vary with the treatment modality. Data from the Bicêtre cohort, and review of the literature.
Briet C, Ilie MD, Kuhn E, Maione L, Brailly-Tabard S, Salenave S, Cariou B, Chanson P
Endocrine 2019 Feb;63(2):348-360. Epub 2018 Nov 5 doi: 10.1007/s12020-018-1797-8. PMID: 30397873

Recent clinical studies

Etiology

Long-term effects of weight-reducing drugs in people with hypertension.
Siebenhofer A, Winterholer S, Jeitler K, Horvath K, Berghold A, Krenn C, Semlitsch T
Cochrane Database Syst Rev 2021 Jan 17;1(1):CD007654. doi: 10.1002/14651858.CD007654.pub5. PMID: 33454957Free PMC Article
Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults.
Nakamura Y, Watanabe H, Tanaka A, Yasui M, Nishihira J, Murayama N
Nutrients 2020 Apr 23;12(4) doi: 10.3390/nu12041191. PMID: 32340375Free PMC Article
Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials.
Rosenstock J, Marquard J, Laffel LM, Neubacher D, Kaspers S, Cherney DZ, Zinman B, Skyler JS, George J, Soleymanlou N, Perkins BA
Diabetes Care 2018 Dec;41(12):2560-2569. Epub 2018 Oct 4 doi: 10.2337/dc18-1749. PMID: 30287422
The effect of potassium supplementation on blood pressure in hypertensive subjects: A systematic review and meta-analysis.
Filippini T, Violi F, D'Amico R, Vinceti M
Int J Cardiol 2017 Mar 1;230:127-135. Epub 2016 Dec 21 doi: 10.1016/j.ijcard.2016.12.048. PMID: 28024910
Beetroot supplementation lowers daily systolic blood pressure in older, overweight subjects.
Jajja A, Sutyarjoko A, Lara J, Rennie K, Brandt K, Qadir O, Siervo M
Nutr Res 2014 Oct;34(10):868-75. Epub 2014 Sep 28 doi: 10.1016/j.nutres.2014.09.007. PMID: 25294299

Diagnosis

Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials.
Karimi E, Abaj F, Gholizadeh M, Asbaghi O, Amini MR, Ghaedi E, Hadi A
Diabetes Res Clin Pract 2023 Aug;202:110801. Epub 2023 Jun 25 doi: 10.1016/j.diabres.2023.110801. PMID: 37369281
Effect of sodium-glucose cotransporter-2 inhibitors on blood pressure in patients with heart failure: a systematic review and meta-analysis.
Li M, Yi T, Fan F, Qiu L, Wang Z, Weng H, Ma W, Zhang Y, Huo Y
Cardiovasc Diabetol 2022 Jul 25;21(1):139. doi: 10.1186/s12933-022-01574-w. PMID: 35879763Free PMC Article
Genetic Determinants and Genotype-Phenotype Correlations in Vietnamese Patients With Dilated Cardiomyopathy.
Nguyen TV, Tran Vu MT, Do TNP, Tran THN, Do TH, Nguyen TMH, Tran Huynh BN, Le LA, Nguyen Pham NT, Nguyen TDA, Nguyen TMN, Le NHP, Pham Nguyen V, Ho Huynh TD
Circ J 2021 Aug 25;85(9):1469-1478. Epub 2021 May 20 doi: 10.1253/circj.CJ-21-0077. PMID: 34011823
Sodium intake and blood pressure in children and adolescents: a systematic review and meta-analysis of experimental and observational studies.
Leyvraz M, Chatelan A, da Costa BR, Taffé P, Paradis G, Bovet P, Bochud M, Chiolero A
Int J Epidemiol 2018 Dec 1;47(6):1796-1810. doi: 10.1093/ije/dyy121. PMID: 29955869
Decreased systolic blood pressure is associated with increased risk of all-cause mortality in patients with type 2 diabetes and renal impairment: A nationwide longitudinal observational study of 27,732 patients based on the Swedish National Diabetes Register.
Svensson MK, Afghahi H, Franzen S, Björk S, Gudbjörnsdottir S, Svensson AM, Eliasson B
Diab Vasc Dis Res 2017 May;14(3):226-235. Epub 2017 Feb 1 doi: 10.1177/1479164116683637. PMID: 28467201

Therapy

Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial.
Laffin LJ, Rodman D, Luther JM, Vaidya A, Weir MR, Rajicic N, Slingsby BT, Nissen SE; Target-HTN Investigators
JAMA 2023 Sep 26;330(12):1140-1150. doi: 10.1001/jama.2023.16029. PMID: 37690061Free PMC Article
Long-term effects of weight-reducing drugs in people with hypertension.
Siebenhofer A, Winterholer S, Jeitler K, Horvath K, Berghold A, Krenn C, Semlitsch T
Cochrane Database Syst Rev 2021 Jan 17;1(1):CD007654. doi: 10.1002/14651858.CD007654.pub5. PMID: 33454957Free PMC Article
Effect of alcohol on blood pressure.
Tasnim S, Tang C, Musini VM, Wright JM
Cochrane Database Syst Rev 2020 Jul 1;7(7):CD012787. doi: 10.1002/14651858.CD012787.pub2. PMID: 32609894Free PMC Article
Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults.
Nakamura Y, Watanabe H, Tanaka A, Yasui M, Nishihira J, Murayama N
Nutrients 2020 Apr 23;12(4) doi: 10.3390/nu12041191. PMID: 32340375Free PMC Article
Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials.
Rosenstock J, Marquard J, Laffel LM, Neubacher D, Kaspers S, Cherney DZ, Zinman B, Skyler JS, George J, Soleymanlou N, Perkins BA
Diabetes Care 2018 Dec;41(12):2560-2569. Epub 2018 Oct 4 doi: 10.2337/dc18-1749. PMID: 30287422

Prognosis

Home versus in-centre haemodialysis for people with kidney failure.
Cheetham MS, Ethier I, Krishnasamy R, Cho Y, Palmer SC, Johnson DW, Craig JC, Stroumza P, Frantzen L, Hegbrant J, Strippoli GF
Cochrane Database Syst Rev 2024 Apr 8;4(4):CD009535. doi: 10.1002/14651858.CD009535.pub3. PMID: 38588450Free PMC Article
Silybin induces endothelium-dependent vasodilation via TRPV4 channels in mouse mesenteric arteries.
Wen X, Peng Y, Zheng B, Yang S, Han J, Yu F, Zhou T, Geng L, Yu Z, Feng L
Hypertens Res 2022 Dec;45(12):1954-1963. Epub 2022 Sep 2 doi: 10.1038/s41440-022-01000-4. PMID: 36056206
Clinical and microbiological characterization of sepsis and evaluation of sepsis scores.
Fuchs A, Tufa TB, Hörner J, Hurissa Z, Nordmann T, Bosselmann M, Abdissa S, Sorsa A, Orth HM, Jensen BO, MacKenzie C, Pfeffer K, Kaasch AJ, Bode JG, Häussinger D, Feldt T
PLoS One 2021;16(3):e0247646. Epub 2021 Mar 4 doi: 10.1371/journal.pone.0247646. PMID: 33661970Free PMC Article
Sodium intake and blood pressure in children and adolescents: a systematic review and meta-analysis of experimental and observational studies.
Leyvraz M, Chatelan A, da Costa BR, Taffé P, Paradis G, Bovet P, Bochud M, Chiolero A
Int J Epidemiol 2018 Dec 1;47(6):1796-1810. doi: 10.1093/ije/dyy121. PMID: 29955869
Decreased systolic blood pressure is associated with increased risk of all-cause mortality in patients with type 2 diabetes and renal impairment: A nationwide longitudinal observational study of 27,732 patients based on the Swedish National Diabetes Register.
Svensson MK, Afghahi H, Franzen S, Björk S, Gudbjörnsdottir S, Svensson AM, Eliasson B
Diab Vasc Dis Res 2017 May;14(3):226-235. Epub 2017 Feb 1 doi: 10.1177/1479164116683637. PMID: 28467201

Clinical prediction guides

Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial.
Laffin LJ, Rodman D, Luther JM, Vaidya A, Weir MR, Rajicic N, Slingsby BT, Nissen SE; Target-HTN Investigators
JAMA 2023 Sep 26;330(12):1140-1150. doi: 10.1001/jama.2023.16029. PMID: 37690061Free PMC Article
Effect of sodium-glucose cotransporter-2 inhibitors on blood pressure in patients with heart failure: a systematic review and meta-analysis.
Li M, Yi T, Fan F, Qiu L, Wang Z, Weng H, Ma W, Zhang Y, Huo Y
Cardiovasc Diabetol 2022 Jul 25;21(1):139. doi: 10.1186/s12933-022-01574-w. PMID: 35879763Free PMC Article
Clinical and microbiological characterization of sepsis and evaluation of sepsis scores.
Fuchs A, Tufa TB, Hörner J, Hurissa Z, Nordmann T, Bosselmann M, Abdissa S, Sorsa A, Orth HM, Jensen BO, MacKenzie C, Pfeffer K, Kaasch AJ, Bode JG, Häussinger D, Feldt T
PLoS One 2021;16(3):e0247646. Epub 2021 Mar 4 doi: 10.1371/journal.pone.0247646. PMID: 33661970Free PMC Article
Hydration Does Not Change Postexercise Hypotension and Its Mechanisms.
Lobo FS, Queiroz ACC, Silva Junior ND, Medina FL, Costa LAR, Tinucci T, Forjaz CLM
J Phys Act Health 2020 May 1;17(5):533-539. doi: 10.1123/jpah.2019-0476. [Epub ahead of print] PMID: 32294620
Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials.
Rosenstock J, Marquard J, Laffel LM, Neubacher D, Kaspers S, Cherney DZ, Zinman B, Skyler JS, George J, Soleymanlou N, Perkins BA
Diabetes Care 2018 Dec;41(12):2560-2569. Epub 2018 Oct 4 doi: 10.2337/dc18-1749. PMID: 30287422

Recent systematic reviews

Effect of sodium-glucose cotransporter-2 inhibitors on blood pressure in patients with heart failure: a systematic review and meta-analysis.
Li M, Yi T, Fan F, Qiu L, Wang Z, Weng H, Ma W, Zhang Y, Huo Y
Cardiovasc Diabetol 2022 Jul 25;21(1):139. doi: 10.1186/s12933-022-01574-w. PMID: 35879763Free PMC Article
Long-term effects of weight-reducing drugs in people with hypertension.
Siebenhofer A, Winterholer S, Jeitler K, Horvath K, Berghold A, Krenn C, Semlitsch T
Cochrane Database Syst Rev 2021 Jan 17;1(1):CD007654. doi: 10.1002/14651858.CD007654.pub5. PMID: 33454957Free PMC Article
Effect of alcohol on blood pressure.
Tasnim S, Tang C, Musini VM, Wright JM
Cochrane Database Syst Rev 2020 Jul 1;7(7):CD012787. doi: 10.1002/14651858.CD012787.pub2. PMID: 32609894Free PMC Article
The effect of potassium supplementation on blood pressure in hypertensive subjects: A systematic review and meta-analysis.
Filippini T, Violi F, D'Amico R, Vinceti M
Int J Cardiol 2017 Mar 1;230:127-135. Epub 2016 Dec 21 doi: 10.1016/j.ijcard.2016.12.048. PMID: 28024910
Impact of GLP-1 receptor agonists on blood pressure, heart rate and hypertension among patients with type 2 diabetes: A systematic review and network meta-analysis.
Sun F, Wu S, Guo S, Yu K, Yang Z, Li L, Zhang Y, Quan X, Ji L, Zhan S
Diabetes Res Clin Pract 2015 Oct;110(1):26-37. Epub 2015 Aug 13 doi: 10.1016/j.diabres.2015.07.015. PMID: 26358202

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