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Acute myocardial infarction

MedGen UID:
57611
•Concept ID:
C0155626
•
Disease or Syndrome
Synonyms: Acute Myocardial Infarction; acute myocardial infarction; acute myocardial infarction (disease); AMI - Acute myocardial infarction; myocardial infarction (disease), acute
SNOMED CT: AMI - Acute myocardial infarction (57054005); Acute myocardial infarction (57054005)
 
Monarch Initiative: MONDO:0004781

Definition

Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Acute myocardial infarction

Professional guidelines

PubMed

Cardiogenic Shock: Pathogenesis, Classification, and Management.
Sarma D, Jentzer JC
Crit Care Clin 2024 Jan;40(1):37-56. Epub 2023 Jul 6 doi: 10.1016/j.ccc.2023.05.001. PMID: 37973356
Fundamental Pathobiology of Coronary Atherosclerosis and Clinical Implications for Chronic Ischemic Heart Disease Management-The Plaque Hypothesis: A Narrative Review.
Stone PH, Libby P, Boden WE
JAMA Cardiol 2023 Feb 1;8(2):192-201. doi: 10.1001/jamacardio.2022.3926. PMID: 36515941Free PMC Article
Management of cardiogenic shock.
Thiele H, de Waha-Thiele S, Freund A, Zeymer U, Desch S, Fitzgerald S
EuroIntervention 2021 Aug 27;17(6):451-465. doi: 10.4244/EIJ-D-20-01296. PMID: 34413010Free PMC Article

Curated

UK NICE guideline NG185, Acute coronary syndromes, 2020

Recent clinical studies

Etiology

Influenza Infection and Acute Myocardial Infarction.
de Boer AR, Riezebos-Brilman A, van Hout D, van Mourik MSM, Rümke LW, de Hoog MLA, Vaartjes I, Bruijning-Verhagen PCJL
NEJM Evid 2024 Jul;3(7):EVIDoa2300361. Epub 2024 Jun 25 doi: 10.1056/EVIDoa2300361. PMID: 38916418
S100A8/A9 as a prognostic biomarker with causal effects for post-acute myocardial infarction heart failure.
Ma J, Li Y, Li P, Yang X, Zhu S, Ma K, Gao F, Gao H, Zhang H, Ma XL, Du J, Li Y
Nat Commun 2024 Mar 27;15(1):2701. doi: 10.1038/s41467-024-46973-7. PMID: 38538601Free PMC Article
Assessment of Inflammatory Hematological Ratios (NLR, PLR, MLR, LMR and Monocyte/HDL-Cholesterol Ratio) in Acute Myocardial Infarction and Particularities in Young Patients.
Tudurachi BS, Anghel L, Tudurachi A, Sascău RA, Stătescu C
Int J Mol Sci 2023 Sep 21;24(18) doi: 10.3390/ijms241814378. PMID: 37762680Free PMC Article
Acute Myocardial Infarction: Etiologies and Mimickers in Young Patients.
Krittanawong C, Khawaja M, Tamis-Holland JE, Girotra S, Rao SV
J Am Heart Assoc 2023 Sep 19;12(18):e029971. doi: 10.1161/JAHA.123.029971. PMID: 37724944Free PMC Article
Acute myocardial infarction.
Reed GW, Rossi JE, Cannon CP
Lancet 2017 Jan 14;389(10065):197-210. Epub 2016 Aug 5 doi: 10.1016/S0140-6736(16)30677-8. PMID: 27502078

Diagnosis

Influenza Infection and Acute Myocardial Infarction.
de Boer AR, Riezebos-Brilman A, van Hout D, van Mourik MSM, Rümke LW, de Hoog MLA, Vaartjes I, Bruijning-Verhagen PCJL
NEJM Evid 2024 Jul;3(7):EVIDoa2300361. Epub 2024 Jun 25 doi: 10.1056/EVIDoa2300361. PMID: 38916418
The Rise of T2.
Nagel E, Pappas L
JACC Cardiovasc Imaging 2024 Jun;17(6):622-624. Epub 2024 May 8 doi: 10.1016/j.jcmg.2024.03.013. PMID: 38727645
Acute Myocardial Infarction: Etiologies and Mimickers in Young Patients.
Krittanawong C, Khawaja M, Tamis-Holland JE, Girotra S, Rao SV
J Am Heart Assoc 2023 Sep 19;12(18):e029971. doi: 10.1161/JAHA.123.029971. PMID: 37724944Free PMC Article
Treatment strategies of acute myocardial infarction: updates on revascularization, pharmacological therapy, and beyond.
Saito Y, Oyama K, Tsujita K, Yasuda S, Kobayashi Y
J Cardiol 2023 Feb;81(2):168-178. Epub 2022 Jul 23 doi: 10.1016/j.jjcc.2022.07.003. PMID: 35882613
The acute myocardial infarction.
Pollard TJ
Prim Care 2000 Sep;27(3):631-49;vi. doi: 10.1016/s0095-4543(05)70167-6. PMID: 10918673

Therapy

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.
Lancet 1988 Aug 13;2(8607):349-60. PMID: 2899772
Thrombolytic therapy. A new strategy for the treatment of acute myocardial infarction (2).
Laffel GL, Braunwald E
N Engl J Med 1984 Sep 20;311(12):770-6. doi: 10.1056/NEJM198409203111205. PMID: 6236369
A randomized trial of propranolol in patients with acute myocardial infarction. I. Mortality results.
JAMA 1982 Mar 26;247(12):1707-14. doi: 10.1001/jama.1982.03320370021023. PMID: 7038157
Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction.
Norwegian Multicenter Study Group
N Engl J Med 1981 Apr 2;304(14):801-7. doi: 10.1056/NEJM198104023041401. PMID: 7010157
Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial.
Hjalmarson A, Elmfeldt D, Herlitz J, Holmberg S, Málek I, Nyberg G, Rydén L, Swedberg K, Vedin A, Waagstein F, Waldenström A, Waldenström J, Wedel H, Wilhelmsen L, Wilhelmsson C
Lancet 1981 Oct 17;2(8251):823-7. doi: 10.1016/s0140-6736(81)91101-6. PMID: 6116950

Prognosis

The landscape of cardiogenic shock: epidemiology and current definitions.
Palacios Ordonez C, Garan AR
Curr Opin Cardiol 2022 May 1;37(3):236-240. Epub 2022 Mar 11 doi: 10.1097/HCO.0000000000000957. PMID: 35275890
Comparison of in-hospital death following ST-elevation myocardial infarction between secondary emergency and tertiary emergency.
Yoshida H, Sakakura K, Yamamoto K, Taniguchi Y, Tsukui T, Seguchi M, Jinnouchi H, Wada H, Moriya T, Fujita H
Cardiovasc Interv Ther 2021 Oct;36(4):444-451. Epub 2020 Aug 30 doi: 10.1007/s12928-020-00698-8. PMID: 32862370Free PMC Article
Recent hospitalization trends for acute myocardial infarction in Beijing.
Eur Heart J 2016 Nov 7;37(42):3188-3189. doi: 10.1093/eurheartj/ehw472. PMID: 27856565
Acute kidney injury: AKI in acute myocardial infarction--are we making progress?
Mehta RL
Nat Rev Nephrol 2012 Apr 10;8(6):322-3. doi: 10.1038/nrneph.2012.80. PMID: 22487701
Post-infarction cardiac rupture: surgical treatment.
Mantovani V, Vanoli D, Chelazzi P, Lepore V, Ferrarese S, Sala A
Eur J Cardiothorac Surg 2002 Nov;22(5):777-80. doi: 10.1016/s1010-7940(02)00485-2. PMID: 12414045

Clinical prediction guides

The Rise of T2.
Nagel E, Pappas L
JACC Cardiovasc Imaging 2024 Jun;17(6):622-624. Epub 2024 May 8 doi: 10.1016/j.jcmg.2024.03.013. PMID: 38727645
Single troponin measurement to rule-out acute myocardial infarction in early presenters.
Andersen CF, Bang C, Lauridsen KG, Frederiksen CA, Schmidt M, Jensen T, Hornung N, Løfgren B
Int J Cardiol 2021 Oct 15;341:15-21. Epub 2021 Aug 13 doi: 10.1016/j.ijcard.2021.08.005. PMID: 34391791
Predictive Pattern for Acute Myocardial Infarction.
Kozik TM, Al-Zaiti SS, Carey MG, Pelter MM
Am J Crit Care 2017 May;26(3):257-258. doi: 10.4037/ajcc2017631. PMID: 28461549
Internal validation of predictive models: efficiency of some procedures for logistic regression analysis.
Steyerberg EW, Harrell FE Jr, Borsboom GJ, Eijkemans MJ, Vergouwe Y, Habbema JD
J Clin Epidemiol 2001 Aug;54(8):774-81. doi: 10.1016/s0895-4356(01)00341-9. PMID: 11470385
Caries prediction--state of the art.
Hausen H
Community Dent Oral Epidemiol 1997 Feb;25(1):87-96. doi: 10.1111/j.1600-0528.1997.tb00904.x. PMID: 9088697

Recent systematic reviews

Effect of SGLT2 inhibitors on heart failure outcomes and cardiovascular death across the cardiometabolic disease spectrum: a systematic review and meta-analysis.
Usman MS, Bhatt DL, Hameed I, Anker SD, Cheng AYY, Hernandez AF, Jones WS, Khan MS, Petrie MC, Udell JA, Friede T, Butler J
Lancet Diabetes Endocrinol 2024 Jul;12(7):447-461. Epub 2024 May 17 doi: 10.1016/S2213-8587(24)00102-5. PMID: 38768620
Complete Percutaneous Coronary Revascularization in Acute Coronary Syndromes With Multivessel Coronary Disease: A Systematic Review.
Faro DC, Laudani C, Agnello FG, Ammirabile N, Finocchiaro S, Legnazzi M, Mauro MS, Mazzone PM, Occhipinti G, Rochira C, Scalia L, Spagnolo M, Greco A, Capodanno D
JACC Cardiovasc Interv 2023 Oct 9;16(19):2347-2364. doi: 10.1016/j.jcin.2023.07.043. PMID: 37821180
Increased risk of acute myocardial infarction after COVID-19 recovery: A systematic review and meta-analysis.
Zuin M, Rigatelli G, Battisti V, Costola G, Roncon L, Bilato C
Int J Cardiol 2023 Feb 1;372:138-143. Epub 2022 Dec 16 doi: 10.1016/j.ijcard.2022.12.032. PMID: 36535564Free PMC Article
Progestin-only contraception and thromboembolism: A systematic review.
Tepper NK, Whiteman MK, Marchbanks PA, James AH, Curtis KM
Contraception 2016 Dec;94(6):678-700. Epub 2016 May 3 doi: 10.1016/j.contraception.2016.04.014. PMID: 27153743Free PMC Article
beta Blockade after myocardial infarction: systematic review and meta regression analysis.
Freemantle N, Cleland J, Young P, Mason J, Harrison J
BMJ 1999 Jun 26;318(7200):1730-7. doi: 10.1136/bmj.318.7200.1730. PMID: 10381708Free PMC Article

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    Clinical resources

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    Curated

    • NICE, 2020
      UK NICE guideline NG185, Acute coronary syndromes, 2020

    Consumer resources

    Reviews

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