U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cortical blindness

MedGen UID:
57834
•Concept ID:
C0155320
•
Disease or Syndrome
Synonyms: Blindness, Cortical; Cortical Blindness
SNOMED CT: Cortical blindness (68574006)
 
Monarch Initiative: MONDO:0001385

Definition

Visual impairment due to visual cortex dysfunction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCortical blindness

Professional guidelines

PubMed

Functional vision disorder: a review of diagnosis, management and costs.
Tao BK, Xie JS, Margolin E
Br J Ophthalmol 2024 Oct 22;108(11):1479-1485. doi: 10.1136/bjo-2023-324856. PMID: 38307720
Advances in the evaluation and management of cortical/cerebral visual impairment in children.
Chang MY, Borchert MS
Surv Ophthalmol 2020 Nov-Dec;65(6):708-724. Epub 2020 Mar 19 doi: 10.1016/j.survophthal.2020.03.001. PMID: 32199940
Phenotypic and genetic spectrum of SCN8A-related disorders, treatment options, and outcomes.
Gardella E, Møller RS
Epilepsia 2019 Dec;60 Suppl 3:S77-S85. doi: 10.1111/epi.16319. PMID: 31904124

Recent clinical studies

Etiology

Contrast-induced encephalopathy following cardiac catheterization.
Spina R, Simon N, Markus R, Muller DW, Kathir K
Catheter Cardiovasc Interv 2017 Aug 1;90(2):257-268. Epub 2016 Nov 29 doi: 10.1002/ccd.26871. PMID: 27896904
Posterior cerebral artery territory infarctions.
Cereda C, Carrera E
Front Neurol Neurosci 2012;30:128-31. Epub 2012 Feb 14 doi: 10.1159/000333610. PMID: 22377879
New approaches to visual rehabilitation for cortical blindness: outcomes and putative mechanisms.
Das A, Huxlin KR
Neuroscientist 2010 Aug;16(4):374-87. Epub 2010 Jan 25 doi: 10.1177/1073858409356112. PMID: 20103505
Reversible posterior leukoencephalopathy syndrome in cancer.
Vaughn C, Zhang L, Schiff D
Curr Oncol Rep 2008 Jan;10(1):86-91. doi: 10.1007/s11912-008-0013-z. PMID: 18366965
Creutzfeldt-Jakob disease and vision.
Armstrong RA
Clin Exp Optom 2006 Jan;89(1):3-9. doi: 10.1111/j.1444-0938.2006.00001.x. PMID: 16430434

Diagnosis

Hepatic cortical blindness.
Xu J, Hao J, Gao Y, Shang L, Qian L, Zhao H
Am J Med Sci 2022 Oct;364(4):492-498. Epub 2022 May 17 doi: 10.1016/j.amjms.2022.04.034. PMID: 35595077
Contrast-induced encephalopathy.
Babalova L, Ruzinak R, Ballova J, Sivak S, Kantorova E, Kurca E, Zelenak K, Nosal V
Bratisl Lek Listy 2021;122(9):618-620. doi: 10.4149/BLL_2021_098. PMID: 34463105
Pediatric abusive head trauma.
Hung KL
Biomed J 2020 Jun;43(3):240-250. Epub 2020 Apr 21 doi: 10.1016/j.bj.2020.03.008. PMID: 32330675Free PMC Article
History of Anosognosia.
Gainotti G
Front Neurol Neurosci 2019;44:75-82. Epub 2019 Apr 30 doi: 10.1159/000494954. PMID: 31220837
A reversible posterior leukoencephalopathy syndrome.
Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR
N Engl J Med 1996 Feb 22;334(8):494-500. doi: 10.1056/NEJM199602223340803. PMID: 8559202

Therapy

Contrast-induced encephalopathy.
Babalova L, Ruzinak R, Ballova J, Sivak S, Kantorova E, Kurca E, Zelenak K, Nosal V
Bratisl Lek Listy 2021;122(9):618-620. doi: 10.4149/BLL_2021_098. PMID: 34463105
Contrast-induced encephalopathy following cardiac catheterization.
Spina R, Simon N, Markus R, Muller DW, Kathir K
Catheter Cardiovasc Interv 2017 Aug 1;90(2):257-268. Epub 2016 Nov 29 doi: 10.1002/ccd.26871. PMID: 27896904
Subacute sclerosing panencephalitis.
Garg RK
J Neurol 2008 Dec;255(12):1861-71. Epub 2008 Oct 14 doi: 10.1007/s00415-008-0032-6. PMID: 18846316
A reversible posterior leukoencephalopathy syndrome.
Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR
N Engl J Med 1996 Feb 22;334(8):494-500. doi: 10.1056/NEJM199602223340803. PMID: 8559202
Neurotoxicity of interferon-alpha.
Merimsky O, Chaitchik S
Anticancer Drugs 1992 Dec;3(6):567-70. doi: 10.1097/00001813-199212000-00002. PMID: 1288726

Prognosis

Pediatric abusive head trauma.
Hung KL
Biomed J 2020 Jun;43(3):240-250. Epub 2020 Apr 21 doi: 10.1016/j.bj.2020.03.008. PMID: 32330675Free PMC Article
Contrast-induced encephalopathy following cardiac catheterization.
Spina R, Simon N, Markus R, Muller DW, Kathir K
Catheter Cardiovasc Interv 2017 Aug 1;90(2):257-268. Epub 2016 Nov 29 doi: 10.1002/ccd.26871. PMID: 27896904
Ocular disease in pregnancy.
Schultz KL, Birnbaum AD, Goldstein DA
Curr Opin Ophthalmol 2005 Oct;16(5):308-14. doi: 10.1097/01.icu.0000179803.42218.cc. PMID: 16175045
Cortical visual impairment in children.
Good WV, Jan JE, DeSa L, Barkovich AJ, Groenveld M, Hoyt CS
Surv Ophthalmol 1994 Jan-Feb;38(4):351-64. doi: 10.1016/0039-6257(94)90073-6. PMID: 8160108
Epileptic nystagmus.
Stolz SE, Chatrian GE, Spence AM
Epilepsia 1991 Nov-Dec;32(6):910-8. doi: 10.1111/j.1528-1157.1991.tb05550.x. PMID: 1743165

Clinical prediction guides

Advances in the evaluation and management of cortical/cerebral visual impairment in children.
Chang MY, Borchert MS
Surv Ophthalmol 2020 Nov-Dec;65(6):708-724. Epub 2020 Mar 19 doi: 10.1016/j.survophthal.2020.03.001. PMID: 32199940
History of Anosognosia.
Gainotti G
Front Neurol Neurosci 2019;44:75-82. Epub 2019 Apr 30 doi: 10.1159/000494954. PMID: 31220837
Contrast-induced encephalopathy following cardiac catheterization.
Spina R, Simon N, Markus R, Muller DW, Kathir K
Catheter Cardiovasc Interv 2017 Aug 1;90(2):257-268. Epub 2016 Nov 29 doi: 10.1002/ccd.26871. PMID: 27896904
Visual function in the brain-damaged child.
Hoyt CS
Eye (Lond) 2003 Apr;17(3):369-84. doi: 10.1038/sj.eye.6700364. PMID: 12724701
Neurotoxicity of radiological contrast agents.
Junck L, Marshall WH
Ann Neurol 1983 May;13(5):469-84. doi: 10.1002/ana.410130502. PMID: 6347033

Recent systematic reviews

Efficacy of perceptual learning in low vision: A systematic review and meta-analysis.
Park ASY, Wong GHT, Tan KWS, Cheung BWS, Oremus M, Cheong AMY, Thompson B
Optom Vis Sci 2024 Jun 1;101(6):305-320. doi: 10.1097/OPX.0000000000002157. PMID: 38990233
Contrast Medium-Induced Transient Cortical Blindness: A Systematic Review of the Literature.
Damavandi PT, Calì D, Negro G, Girombelli A, Lattanzi S
J Vasc Interv Radiol 2024 Oct;35(10):1439-1446.e16. Epub 2024 Jun 19 doi: 10.1016/j.jvir.2024.06.007. PMID: 38906244
Clinical management of contrast-induced neurotoxicity: a systematic review.
Mariajoseph FP, Chung JX, Lai LT, Moore J, Goldschlager T, Chandra RV, Praeger A, Slater LA
Acta Neurol Belg 2024 Aug;124(4):1141-1149. Epub 2024 Feb 8 doi: 10.1007/s13760-024-02474-4. PMID: 38329641Free PMC Article
Contrast-induced neurotoxicity related to neurological endovascular procedures: a systematic review.
Quintas-Neves M, Araújo JM, Xavier SA, Amorim JM, Cruz E Silva V, Pinho J
Acta Neurol Belg 2020 Dec;120(6):1419-1424. Epub 2020 Sep 30 doi: 10.1007/s13760-020-01508-x. PMID: 32997325
Central nervous system involvement in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Report of 26 patients and review of the literature.
André R, Cottin V, Saraux JL, Blaison G, Bienvenu B, Cathebras P, Dhote R, Foucher A, Gil H, Lapoirie J, Launay D, Loustau V, Maurier F, Pertuiset E, Zénone T, Seebach J, Costedoat-Chalumeau N, Puéchal X, Mouthon L, Guillevin L, Terrier B; French Vasculitis Study Group (FVSG)
Autoimmun Rev 2017 Sep;16(9):963-969. Epub 2017 Jul 12 doi: 10.1016/j.autrev.2017.07.007. PMID: 28709761

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...