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Parasystole

MedGen UID:
60067
Concept ID:
C0206068
Pathologic Function
Synonym: Parasystoles
SNOMED CT: Parasystole (10164001); Parasystolic beat (10164001)

Definition

A cardiac arrhythmia that is caused by interaction of two independently initiated cardiac impulses of different rates from two separate foci. Generally one focus is the SINOATRIAL NODE, the normal pacemaker. The ectopic focus is usually in the HEART VENTRICLE but can be in the HEART ATRIUM or the ATRIOVENTRICULAR NODE. Modulation of the parasystolic rhythm by the sinus rhythm depends on the completeness of entrance block surrounding the parasystolic focus. [from MeSH]

Professional guidelines

PubMed

Ren Z, Zhou J, Xu G, Xian T, Xie L, Zhuang Y
Chin Med J (Engl) 1999 Nov;112(11):992-4. PMID: 11721482
Bayley TJ
Br Med J 1971 Aug;3(5772):456-8. doi: 10.1136/bmj.3.5772.456. PMID: 5567769Free PMC Article

Recent clinical studies

Etiology

Do DH, O'Meara K, Lee J, Meyer S, Hanna P, Mori S, Fishbein MC, Boyle NG, Elizari MV, Bradfield JS, Shivkumar K
JACC Clin Electrophysiol 2023 Jul;9(7 Pt 1):936-948. Epub 2023 Feb 22 doi: 10.1016/j.jacep.2022.11.014. PMID: 37438043
Buchhorn R, Christian W
Cardiol Young 2014 Feb;24(1):120-5. Epub 2013 Feb 12 doi: 10.1017/S104795111200234X. PMID: 23402394
Meyer T, Maier A, Borisow N, Dullinger JS, Splettstösser G, Ohlraun S, Münch C, Linke P
J Neurol 2008 Apr;255(4):587-91. Epub 2008 Apr 21 doi: 10.1007/s00415-008-0756-3. PMID: 18425621
Ren Z, Zhou J, Xu G, Xian T, Xie L, Zhuang Y
Chin Med J (Engl) 1999 Nov;112(11):992-4. PMID: 11721482
Campbell RW
Eur Heart J 1984 Mar;5 Suppl A:95-8. doi: 10.1093/eurheartj/5.suppl_a.95. PMID: 6373292

Diagnosis

Yadlapati A, Kim SS, Knight BP
Pacing Clin Electrophysiol 2017 Jan;40(1):67-68. Epub 2016 Dec 22 doi: 10.1111/pace.12980. PMID: 27868219
Johnson CD
Bol Asoc Med P R 1996 Jul-Sep;88(7-9):73-81. PMID: 8962529
Pick A, Langendorf R
Med Clin North Am 1976 Jan;60(1):125-47. doi: 10.1016/s0025-7125(16)31923-x. PMID: 1246166
Steffens TG, Gettes LS
Cardiovasc Clin 1974;6(1):99-110. PMID: 4611617
Chung EK
Prog Cardiovasc Dis 1968 Jul;11(1):64-81. doi: 10.1016/s0033-0620(68)80012-x. PMID: 4172854

Therapy

Nakamura K, Sasaki T, Minami K, Sasaki W, Kimura K, Take Y, Naito S
JACC Clin Electrophysiol 2021 Mar;7(3):431-432. doi: 10.1016/j.jacep.2020.12.022. PMID: 33736762
Yadlapati A, Kim SS, Knight BP
Pacing Clin Electrophysiol 2017 Jan;40(1):67-68. Epub 2016 Dec 22 doi: 10.1111/pace.12980. PMID: 27868219
Castellanos A, Mendoza IJ, Luceri RM, Castillo CA, Zaman L, Saoudi N, Myerburg RJ
Am J Cardiol 1985 May 1;55(11):1344-9. doi: 10.1016/0002-9149(85)90501-6. PMID: 3993567
Santinelli V, Chiariello M, Clarizia M, Riviezzo G, Condorelli M
Am Heart J 1984 Oct;108(4 Pt 1):1029-31. doi: 10.1016/0002-8703(84)90472-1. PMID: 6485980
Chung EK
Prog Cardiovasc Dis 1968 Jul;11(1):64-81. doi: 10.1016/s0033-0620(68)80012-x. PMID: 4172854

Prognosis

Do DH, O'Meara K, Lee J, Meyer S, Hanna P, Mori S, Fishbein MC, Boyle NG, Elizari MV, Bradfield JS, Shivkumar K
JACC Clin Electrophysiol 2023 Jul;9(7 Pt 1):936-948. Epub 2023 Feb 22 doi: 10.1016/j.jacep.2022.11.014. PMID: 37438043
McIntyre WF, Baranchuk A
Arch Cardiovasc Dis 2011 May;104(5):359-60. Epub 2011 Mar 26 doi: 10.1016/j.acvd.2010.09.008. PMID: 21693373
Glass L, Goldberger AL, Bélair J
Am J Physiol 1986 Oct;251(4 Pt 2):H841-7. doi: 10.1152/ajpheart.1986.251.4.H841. PMID: 3766761
Campbell RW
Eur Heart J 1984 Mar;5 Suppl A:95-8. doi: 10.1093/eurheartj/5.suppl_a.95. PMID: 6373292
Chung EK
Prog Cardiovasc Dis 1968 Jul;11(1):64-81. doi: 10.1016/s0033-0620(68)80012-x. PMID: 4172854

Clinical prediction guides

Xiang JT
Curr Med Sci 2020 Dec;40(6):1191-1202. Epub 2021 Jan 11 doi: 10.1007/s11596-020-2308-8. PMID: 33428149
Castellanos A, Moleiro F, Guerrero J, Awaad MI, Myerburg RJ
J Electrocardiol 1997 Oct;30(4):331-5. doi: 10.1016/s0022-0736(97)80046-5. PMID: 9375910
Glass L, Goldberger AL, Bélair J
Am J Physiol 1986 Oct;251(4 Pt 2):H841-7. doi: 10.1152/ajpheart.1986.251.4.H841. PMID: 3766761
Kinoshita S, Nakagawa K, Kato N, Nishino T, Tanabe Y
Circulation 1982 Jan;65(1):208-12. doi: 10.1161/01.cir.65.1.208. PMID: 6171360
Kuo CS, Surawicz B
Am J Cardiol 1979 Sep;44(3):435-41. doi: 10.1016/0002-9149(79)90393-x. PMID: 474422

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