U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Iris nodule

MedGen UID:
603499
•Concept ID:
C0424839
•
Finding
SNOMED CT: Iris nodule (248510004)
 
HPO: HP:0034819

Definition

The presence of a nodule (small rounded lump of tissue) in the iris. [from HPO]

Professional guidelines

PubMed

Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline - Update 2022.
Gauci ML, Aristei C, Becker JC, Blom A, Bataille V, Dreno B, Del Marmol V, Forsea AM, Fargnoli MC, Grob JJ, Gomes F, Hauschild A, Hoeller C, Harwood C, Kelleners-Smeets N, Kaufmann R, Lallas A, Malvehy J, Moreno-Ramirez D, Peris K, Pellacani G, Saiag P, Stratigos AJ, Vieira R, Zalaudek I, van Akkooi ACJ, Lorigan P, Garbe C, Lebbé C; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2022 Aug;171:203-231. Epub 2022 Jun 19 doi: 10.1016/j.ejca.2022.03.043. PMID: 35732101
Primary Tumour Type, Clinical Features, Treatment and Outcome of Patients with Iris Metastasis.
Liu T, Bai F, Yang L, Liu L, Xiao J, Liu X
Ocul Immunol Inflamm 2022 Oct-Nov;30(7-8):1726-1732. Epub 2021 Jul 6 doi: 10.1080/09273948.2021.1939392. PMID: 34228589
Ocular sarcoidosis: new diagnostic modalities and treatment.
Yang SJ, Salek S, Rosenbaum JT
Curr Opin Pulm Med 2017 Sep;23(5):458-467. doi: 10.1097/MCP.0000000000000409. PMID: 28622198Free PMC Article

Recent clinical studies

Etiology

Management of Fusarium keratitis and its associated fungal iris nodule with intracameral voriconazole and amphotericin B.
Lai J, Pandya V, McDonald R, Sutton G
Clin Exp Optom 2014 Mar;97(2):181-3. Epub 2013 Aug 5 doi: 10.1111/cxo.12091. PMID: 23909894
The consequences of abandonment of the bandage lens patient--the cause of an inflammatory iris nodule simulating metastasis from a transitional cell tumor of the bladder.
Jones AR, Gandhewar R, Prasad A, Blyth CP
Cont Lens Anterior Eye 2005 Sep;28(3):135-6. Epub 2005 Jun 15 doi: 10.1016/j.clae.2005.04.002. PMID: 16318844
Ocular involvement in patients with posttransplant lymphoproliferative disorder.
Cho AS, Holland GN, Glasgow BJ, Isenberg SJ, George BL, McDiarmid SV
Arch Ophthalmol 2001 Feb;119(2):183-9. PMID: 11176978

Diagnosis

Long-term course with iris changes after trabeculectomy for uveitic glaucoma associated with iris mammillation: a case report.
Usui S, Okazaki T, Fujino T, Kawashima R, Hashida N, Matsushita K, Morii E, Nishida K
BMC Ophthalmol 2023 Mar 15;23(1):103. doi: 10.1186/s12886-023-02854-z. PMID: 36922780Free PMC Article
Chronic postoperative fungal endophthalmitis caused by Penicillium citrinum after cataract surgery.
Garg A, Stuart A, Fajgenbaum M, Laidlaw DA, Stanford M
J Cataract Refract Surg 2016 Sep;42(9):1380-1382. doi: 10.1016/j.jcrs.2016.07.025. PMID: 27697258
Management of Fusarium keratitis and its associated fungal iris nodule with intracameral voriconazole and amphotericin B.
Lai J, Pandya V, McDonald R, Sutton G
Clin Exp Optom 2014 Mar;97(2):181-3. Epub 2013 Aug 5 doi: 10.1111/cxo.12091. PMID: 23909894
The consequences of abandonment of the bandage lens patient--the cause of an inflammatory iris nodule simulating metastasis from a transitional cell tumor of the bladder.
Jones AR, Gandhewar R, Prasad A, Blyth CP
Cont Lens Anterior Eye 2005 Sep;28(3):135-6. Epub 2005 Jun 15 doi: 10.1016/j.clae.2005.04.002. PMID: 16318844
Ocular involvement in patients with posttransplant lymphoproliferative disorder.
Cho AS, Holland GN, Glasgow BJ, Isenberg SJ, George BL, McDiarmid SV
Arch Ophthalmol 2001 Feb;119(2):183-9. PMID: 11176978

Therapy

Management of Fusarium keratitis and its associated fungal iris nodule with intracameral voriconazole and amphotericin B.
Lai J, Pandya V, McDonald R, Sutton G
Clin Exp Optom 2014 Mar;97(2):181-3. Epub 2013 Aug 5 doi: 10.1111/cxo.12091. PMID: 23909894
The consequences of abandonment of the bandage lens patient--the cause of an inflammatory iris nodule simulating metastasis from a transitional cell tumor of the bladder.
Jones AR, Gandhewar R, Prasad A, Blyth CP
Cont Lens Anterior Eye 2005 Sep;28(3):135-6. Epub 2005 Jun 15 doi: 10.1016/j.clae.2005.04.002. PMID: 16318844
Ocular involvement in patients with posttransplant lymphoproliferative disorder.
Cho AS, Holland GN, Glasgow BJ, Isenberg SJ, George BL, McDiarmid SV
Arch Ophthalmol 2001 Feb;119(2):183-9. PMID: 11176978
Primary intraocular posttransplantation lymphoproliferative disorder.
Clark WL, Scott IU, Murray TG, Rosa RH Jr, Siatkowski RM, Langham MR Jr
Arch Ophthalmol 1998 Dec;116(12):1667-9. doi: 10.1001/archopht.116.12.1667. PMID: 9869802
The treatment of an enlarged sarcoid iris nodule with injectable corticosteroids.
Mader TH, Chismire KJ, Cornell FM
Am J Ophthalmol 1988 Sep 15;106(3):365-6. doi: 10.1016/0002-9394(88)90384-4. PMID: 3421302

Prognosis

Long-term course with iris changes after trabeculectomy for uveitic glaucoma associated with iris mammillation: a case report.
Usui S, Okazaki T, Fujino T, Kawashima R, Hashida N, Matsushita K, Morii E, Nishida K
BMC Ophthalmol 2023 Mar 15;23(1):103. doi: 10.1186/s12886-023-02854-z. PMID: 36922780Free PMC Article
Chronic postoperative fungal endophthalmitis caused by Penicillium citrinum after cataract surgery.
Garg A, Stuart A, Fajgenbaum M, Laidlaw DA, Stanford M
J Cataract Refract Surg 2016 Sep;42(9):1380-1382. doi: 10.1016/j.jcrs.2016.07.025. PMID: 27697258
The consequences of abandonment of the bandage lens patient--the cause of an inflammatory iris nodule simulating metastasis from a transitional cell tumor of the bladder.
Jones AR, Gandhewar R, Prasad A, Blyth CP
Cont Lens Anterior Eye 2005 Sep;28(3):135-6. Epub 2005 Jun 15 doi: 10.1016/j.clae.2005.04.002. PMID: 16318844

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...