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Endometrioid carcinoma

MedGen UID:
61661
Concept ID:
C0206687
Neoplastic Process
Synonyms: Carcinoma, Endometrioid; Carcinomas, Endometrioid; Endometrioid Carcinoma; Endometrioid Carcinomas
SNOMED CT: Endometrioid carcinoma (30289006)

Definition

An adenocarcinoma characterized by the presence of cells resembling the glandular cells of the ENDOMETRIUM. It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of this form of adenocarcinoma in both tissues. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndometrioid carcinoma

Professional guidelines

PubMed

Abu-Rustum N, Yashar C, Arend R, Barber E, Bradley K, Brooks R, Campos SM, Chino J, Chon HS, Chu C, Crispens MA, Damast S, Fisher CM, Frederick P, Gaffney DK, Giuntoli R, Han E, Holmes J, Howitt BE, Lea J, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Podoll M, Salani R, Schorge J, Siedel J, Sisodia R, Soliman P, Ueda S, Urban R, Wethington SL, Wyse E, Zanotti K, McMillian NR, Aggarwal S
J Natl Compr Canc Netw 2023 Feb;21(2):181-209. doi: 10.6004/jnccn.2023.0006. PMID: 36791750
Matsushita C, Fujiwara H, Takei Y, Saga Y, Machida S, Taneichi A, Takahashi S, Yoshiba T, Koyanagi T, Takahashi Y, Morisawa H, Suzuki M
Int J Gynecol Cancer 2019 Mar;29(3):541-546. Epub 2019 Jan 10 doi: 10.1136/ijgc-2018-000044. PMID: 30630888
Cobb LP, Gershenson DM
Hematol Oncol Clin North Am 2018 Dec;32(6):1011-1024. doi: 10.1016/j.hoc.2018.07.015. PMID: 30390757

Recent clinical studies

Etiology

J Obstet Gynaecol Res 2023 Mar;49 Suppl 1:84-86. doi: 10.1111/jog.15587. PMID: 36945814
Vermij L, Smit V, Nout R, Bosse T
Histopathology 2020 Jan;76(1):52-63. doi: 10.1111/his.14015. PMID: 31846532Free PMC Article
Murakami K, Kotani Y, Shiro R, Takaya H, Nakai H, Matsumura N
Int J Clin Oncol 2020 Jan;25(1):51-58. Epub 2019 Aug 31 doi: 10.1007/s10147-019-01536-5. PMID: 31473885
Cobb LP, Gershenson DM
Hematol Oncol Clin North Am 2018 Dec;32(6):1011-1024. doi: 10.1016/j.hoc.2018.07.015. PMID: 30390757
Young RH
Pathology 2018 Jan;50(1):5-15. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.007. PMID: 29132723

Diagnosis

De Boeck A, Nohr E, El-Hallani S, Ghatage P, Lee CH, Köbel M
Int J Gynecol Pathol 2025 Jan 1;44(1):72-78. Epub 2024 May 29 doi: 10.1097/PGP.0000000000001039. PMID: 38833721
Gupta H, Sancheti S, Somal PK, Sali AP
Int J Gynecol Cancer 2023 Apr 3;33(4):643-644. doi: 10.1136/ijgc-2022-004001. PMID: 37011921
Li JJX, Ip PPC
Surg Pathol Clin 2022 Jun;15(2):277-299. doi: 10.1016/j.path.2022.02.006. PMID: 35715162
Murali R, Davidson B, Fadare O, Carlson JA, Crum CP, Gilks CB, Irving JA, Malpica A, Matias-Guiu X, McCluggage WG, Mittal K, Oliva E, Parkash V, Rutgers JKL, Staats PN, Stewart CJR, Tornos C, Soslow RA
Int J Gynecol Pathol 2019 Jan;38 Suppl 1(Iss 1 Suppl 1):S40-S63. doi: 10.1097/PGP.0000000000000491. PMID: 30550483Free PMC Article
Cobb LP, Gershenson DM
Hematol Oncol Clin North Am 2018 Dec;32(6):1011-1024. doi: 10.1016/j.hoc.2018.07.015. PMID: 30390757

Therapy

Yu ZC, Li T, Tully E, Huang P, Chen CN, Oberdoerffer P, Gaillard S, Shih IM, Wang TL
Cancer Res 2023 Aug 15;83(16):2750-2762. doi: 10.1158/0008-5472.CAN-22-3646. PMID: 37306706Free PMC Article
van den Heerik ASVM, Horeweg N, Nout RA, Lutgens LCHW, van der Steen-Banasik EM, Westerveld GH, van den Berg HA, Slot A, Koppe FLA, Kommoss S, Mens JWM, Nowee ME, Bijmolt S, Cibula D, Stam TC, Jurgenliemk-Schulz IM, Snyers A, Hamann M, Zwanenburg AG, Coen VLMA, Vandecasteele K, Gillham C, Chargari C, Verhoeven-Adema KW, Putter H, van den Hout WB, Wortman BG, Nijman HW, Bosse T, Creutzberg CL
Int J Gynecol Cancer 2020 Dec;30(12):2002-2007. Epub 2020 Oct 12 doi: 10.1136/ijgc-2020-001929. PMID: 33046573Free PMC Article
Vermij L, Smit V, Nout R, Bosse T
Histopathology 2020 Jan;76(1):52-63. doi: 10.1111/his.14015. PMID: 31846532Free PMC Article
Moore K, Colombo N, Scambia G, Kim BG, Oaknin A, Friedlander M, Lisyanskaya A, Floquet A, Leary A, Sonke GS, Gourley C, Banerjee S, Oza A, González-Martín A, Aghajanian C, Bradley W, Mathews C, Liu J, Lowe ES, Bloomfield R, DiSilvestro P
N Engl J Med 2018 Dec 27;379(26):2495-2505. Epub 2018 Oct 21 doi: 10.1056/NEJMoa1810858. PMID: 30345884
de Boer SM, Powell ME, Mileshkin L, Katsaros D, Bessette P, Haie-Meder C, Ottevanger PB, Ledermann JA, Khaw P, Colombo A, Fyles A, Baron MH, Jürgenliemk-Schulz IM, Kitchener HC, Nijman HW, Wilson G, Brooks S, Carinelli S, Provencher D, Hanzen C, Lutgens LCHW, Smit VTHBM, Singh N, Do V, D'Amico R, Nout RA, Feeney A, Verhoeven-Adema KW, Putter H, Creutzberg CL; PORTEC study group
Lancet Oncol 2018 Mar;19(3):295-309. Epub 2018 Feb 12 doi: 10.1016/S1470-2045(18)30079-2. PMID: 29449189Free PMC Article

Prognosis

Matsuo K, Matsuzaki S, Miller H, Nusbaum DJ, Walia S, Matsuzaki S, Shimada M, Klar M, Roman LD
J Surg Oncol 2021 Sep;124(4):687-698. Epub 2021 Jun 12 doi: 10.1002/jso.26570. PMID: 34118157
Murakami K, Kotani Y, Shiro R, Takaya H, Nakai H, Matsumura N
Int J Clin Oncol 2020 Jan;25(1):51-58. Epub 2019 Aug 31 doi: 10.1007/s10147-019-01536-5. PMID: 31473885
Tracey EH, Modi B, Micheletti RG
Am J Dermatopathol 2017 Jan;39(1):e1-e2. doi: 10.1097/DAD.0000000000000645. PMID: 27415636
Jang SG, Yoo CW, Park SY, Kang S, Kim HK
Int J Gynecol Cancer 2014 Nov;24(9):1558-63. doi: 10.1097/IGC.0000000000000267. PMID: 25238166
Gaertner EM, Farley JH, Taylor RR, Silver SA
Int J Gynecol Pathol 1999 Oct;18(4):396-401. doi: 10.1097/00004347-199910000-00017. PMID: 10542951

Clinical prediction guides

de Nonneville A, Kalbacher E, Cannone F, Guille A, Adelaïde J, Finetti P, Cappiello M, Lambaudie E, Ettore G, Charafe E, Mamessier E, Provansal M, Bertucci F, Sabatier R
Mol Oncol 2024 Oct;18(10):2586-2600. Epub 2024 Jun 25 doi: 10.1002/1878-0261.13679. PMID: 38923749Free PMC Article
Giglio A, Miller B, Curcio E, Kuo YH, Erler B, Bosscher J, Hicks V, ElSahwi K
JSLS 2020 Apr-Jun;24(2) doi: 10.4293/JSLS.2020.00011. PMID: 32425481Free PMC Article
León-Castillo A, Britton H, McConechy MK, McAlpine JN, Nout R, Kommoss S, Brucker SY, Carlson JW, Epstein E, Rau TT, Bosse T, Church DN, Gilks CB
J Pathol 2020 Mar;250(3):323-335. Epub 2020 Jan 29 doi: 10.1002/path.5372. PMID: 31829442Free PMC Article
Murakami K, Kotani Y, Shiro R, Takaya H, Nakai H, Matsumura N
Int J Clin Oncol 2020 Jan;25(1):51-58. Epub 2019 Aug 31 doi: 10.1007/s10147-019-01536-5. PMID: 31473885
Bosse T, Nout RA, McAlpine JN, McConechy MK, Britton H, Hussein YR, Gonzalez C, Ganesan R, Steele JC, Harrison BT, Oliva E, Vidal A, Matias-Guiu X, Abu-Rustum NR, Levine DA, Gilks CB, Soslow RA
Am J Surg Pathol 2018 May;42(5):561-568. doi: 10.1097/PAS.0000000000001020. PMID: 29505428Free PMC Article

Recent systematic reviews

Mitric C, Salman L, Abrahamyan L, Kim SR, Pechlivanoglou P, Chan KKW, Gien LT, Ferguson SE
Gynecol Oncol 2023 Mar;170:133-142. Epub 2023 Jan 20 doi: 10.1016/j.ygyno.2022.12.008. PMID: 36682091
Travaglino A, Raffone A, Mollo A, Borrelli G, Alfano P, Zannoni GF, Insabato L, Zullo F
Arch Gynecol Obstet 2020 May;301(5):1117-1125. Epub 2020 Apr 6 doi: 10.1007/s00404-020-05531-4. PMID: 32253551
Jia M, Sun PL, Gao H
Diagn Pathol 2019 Nov 18;14(1):129. doi: 10.1186/s13000-019-0909-y. PMID: 31739799Free PMC Article
Galazis N, Pang YL, Galazi M, Haoula Z, Layfield R, Atiomo W
Gynecol Endocrinol 2013 Jul;29(7):638-44. Epub 2013 Mar 25 doi: 10.3109/09513590.2013.777416. PMID: 23527552
AlHilli MM, Hopkins MR, Famuyide AO
J Minim Invasive Gynecol 2011 May-Jun;18(3):393-400. doi: 10.1016/j.jmig.2011.02.004. PMID: 21545966

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