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Abnormal blood oxygen level

MedGen UID:
663395
•Concept ID:
C0580517
•
Finding
Synonyms: Abnormal blood O2 level; Abnormal blood oxygen levels; Abnormal O2 blood concentration; Blood oxygen level abnormal; Blood oxygen level outside reference range
SNOMED CT: Blood oxygen level abnormal (167026000); Blood oxygen level outside reference range (167026000)
 
HPO: HP:0500165

Definition

An abnormality of the partial pressure of oxygen in the arterial blood. [from HPO]

Professional guidelines

PubMed

Eisenmenger syndrome: diagnosis, prognosis and clinical management.
Arvanitaki A, Giannakoulas G, Baumgartner H, Lammers AE
Heart 2020 Nov;106(21):1638-1645. Epub 2020 Jul 20 doi: 10.1136/heartjnl-2020-316665. PMID: 32690623
Clinical Practice Guideline: Tonsillectomy in Children (Update)-Executive Summary.
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(2):187-205. doi: 10.1177/0194599818807917. PMID: 30921525
Clinical Practice Guideline: Tonsillectomy in Children (Update).
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(1_suppl):S1-S42. doi: 10.1177/0194599818801757. PMID: 30798778

Recent clinical studies

Etiology

Regional Glymphatic Abnormality in Behavioral Variant Frontotemporal Dementia.
Jiang D, Liu L, Kong Y, Chen Z, Rosa-Neto P, Chen K, Ren L, Chu M, Wu L; Frontotemporal Lobar Degeneration Neuroimaging Initiative
Ann Neurol 2023 Sep;94(3):442-456. Epub 2023 Jun 14 doi: 10.1002/ana.26710. PMID: 37243334Free PMC Article
Coblation supraglottoplasty: a ten-year experience in a tertiary referral hospital.
El-Sobki A, Ibrahim RAE, Amer A, Hashish MI, El-Deeb ME, El-Kholy NA, Abdelmeguid AS
Eur Arch Otorhinolaryngol 2022 Feb;279(2):865-874. Epub 2021 Oct 16 doi: 10.1007/s00405-021-07130-8. PMID: 34654950
Use of a Digital Monitoring Platform to Improve Outcomes in Infants With a Single Ventricle.
Vergales J, Peregoy L, Zalewski J, Plummer ST
World J Pediatr Congenit Heart Surg 2020 Nov;11(6):753-759. doi: 10.1177/2150135120945596. PMID: 33164687
Oxygen Saturation and Perfusion Index-Based Enhanced Critical Congenital Heart Disease Screening.
Siefkes H, Kair L, Tancredi DJ, Vasquez B, Garcia L, Bedford-Mu C, Lakshminrusimha S
Am J Perinatol 2020 Jan;37(2):158-165. Epub 2019 Apr 19 doi: 10.1055/s-0039-1685445. PMID: 31003242
Postoperative management: the role of mixed venous oxygen saturation monitoring.
Bradley SM, Atz AM
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2005:22-7. doi: 10.1053/j.pcsu.2005.01.002. PMID: 15818354

Diagnosis

Assessment of bone mineral density in children with congenital cyanotic heart disease.
Elsharkawy AA, El-Hawary AK, Alsawah GA, Aboelenin HM, Awad MH
Cardiol Young 2022 Jan;32(1):71-76. Epub 2021 Apr 26 doi: 10.1017/S1047951121001554. PMID: 33896435
Eisenmenger syndrome: diagnosis, prognosis and clinical management.
Arvanitaki A, Giannakoulas G, Baumgartner H, Lammers AE
Heart 2020 Nov;106(21):1638-1645. Epub 2020 Jul 20 doi: 10.1136/heartjnl-2020-316665. PMID: 32690623
Oxygen Saturation and Perfusion Index-Based Enhanced Critical Congenital Heart Disease Screening.
Siefkes H, Kair L, Tancredi DJ, Vasquez B, Garcia L, Bedford-Mu C, Lakshminrusimha S
Am J Perinatol 2020 Jan;37(2):158-165. Epub 2019 Apr 19 doi: 10.1055/s-0039-1685445. PMID: 31003242
Pulse oximetry screening for critical congenital heart defects.
Plana MN, Zamora J, Suresh G, Fernandez-Pineda L, Thangaratinam S, Ewer AK
Cochrane Database Syst Rev 2018 Mar 1;3(3):CD011912. doi: 10.1002/14651858.CD011912.pub2. PMID: 29494750Free PMC Article
Scimitar syndrome.
Ielasi A, Latib A, Agricola E, Montorfano M, Colombo A
J Cardiovasc Med (Hagerstown) 2011 Mar;12(3):176-7. doi: 10.2459/JCM.0b013e328332f3e2. PMID: 20093947

Therapy

Intraoperative Regional Cerebral Oxygenation During Pediatric Thoracoscopic Surgery: A Systematic Review.
Prasad G, Singh A, Kainth D, Khanna P, Anand S
J Laparoendosc Adv Surg Tech A 2024 Mar;34(3):274-279. Epub 2023 Oct 20 doi: 10.1089/lap.2023.0228. PMID: 37862569
Ebstein's anomaly with 'reversible' functional pulmonary atresia.
Rato J, R Sousa A, Teixeira A, Anjos R
BMJ Case Rep 2019 Dec 29;12(12) doi: 10.1136/bcr-2019-229809. PMID: 31888914Free PMC Article
Pulse oximetry screening for critical congenital heart defects.
Plana MN, Zamora J, Suresh G, Fernandez-Pineda L, Thangaratinam S, Ewer AK
Cochrane Database Syst Rev 2018 Mar 1;3(3):CD011912. doi: 10.1002/14651858.CD011912.pub2. PMID: 29494750Free PMC Article
Causes of the difficult airway.
Orfanos JG, Quereshy FA
Atlas Oral Maxillofac Surg Clin North Am 2010 Mar;18(1):1-9. doi: 10.1016/j.cxom.2009.11.001. PMID: 20176322
Bidirectional Glenn procedure without cardiopulmonary bypass.
Liu J, Lu Y, Chen H, Shi Z, Su Z, Ding W
Ann Thorac Surg 2004 Apr;77(4):1349-52. doi: 10.1016/j.athoracsur.2003.06.024. PMID: 15063264

Prognosis

Abnormally low regional cerebral oxygen saturation after induction of anesthesia without neurological abnormality: A case report.
Honda J, Tanaka S, Yoshida K, Inoue S
Ann Card Anaesth 2023 Oct-Dec;26(4):442-445. doi: 10.4103/aca.aca_194_22. PMID: 37861582Free PMC Article
Balloon Valvuloplasty via the Pulmonary Artery Trunk for Treating Neonates With Severe Pulmonary Valve Disease.
Huang KA, Dai X, Liao D, Li Q
Heart Surg Forum 2021 Feb 19;24(1):E185-E187. doi: 10.1532/hsf.3423. PMID: 33635246
Contrast Echocardiogram for the Evaluation of Streaming in a Single-Ventricle Patient.
Miura S, Ookoshi Y, Momoki K, Hoshino K, Ueta I
Pediatr Cardiol 2019 Jan;40(1):216-218. Epub 2018 Oct 10 doi: 10.1007/s00246-018-1997-2. PMID: 30306199
Transposition of the great arteries: When echocardiography does not match the clinical picture.
Dhillon GS, Fernandes CJ, Khan A, Heinle JS, Lopez KN
J Clin Ultrasound 2018 Nov;46(9):617-622. Epub 2018 Aug 30 doi: 10.1002/jcu.22615. PMID: 30160304Free PMC Article
Clinical use of blade atrial septostomy.
Park SC, Neches WH, Zuberbuhler JR, Lenox CC, Mathews RA, Fricker FJ, Zoltun RA
Circulation 1978 Oct;58(4):600-6. doi: 10.1161/01.cir.58.4.600. PMID: 688569

Clinical prediction guides

Assessment of bone mineral density in children with congenital cyanotic heart disease.
Elsharkawy AA, El-Hawary AK, Alsawah GA, Aboelenin HM, Awad MH
Cardiol Young 2022 Jan;32(1):71-76. Epub 2021 Apr 26 doi: 10.1017/S1047951121001554. PMID: 33896435
Use of a Digital Monitoring Platform to Improve Outcomes in Infants With a Single Ventricle.
Vergales J, Peregoy L, Zalewski J, Plummer ST
World J Pediatr Congenit Heart Surg 2020 Nov;11(6):753-759. doi: 10.1177/2150135120945596. PMID: 33164687
Assessment of functional capacity among students with univentricular heart.
Ampuero C, Silva R, Valderrama P, Covarrubias E, Astudillo P, Zelada P, Clavería C
Arch Argent Pediatr 2020 Oct;118(5):343-349. doi: 10.5546/aap.2020.eng.343. PMID: 32924398
Eisenmenger syndrome: diagnosis, prognosis and clinical management.
Arvanitaki A, Giannakoulas G, Baumgartner H, Lammers AE
Heart 2020 Nov;106(21):1638-1645. Epub 2020 Jul 20 doi: 10.1136/heartjnl-2020-316665. PMID: 32690623
Scimitar syndrome.
Ielasi A, Latib A, Agricola E, Montorfano M, Colombo A
J Cardiovasc Med (Hagerstown) 2011 Mar;12(3):176-7. doi: 10.2459/JCM.0b013e328332f3e2. PMID: 20093947

Recent systematic reviews

Antioxidant supplementation for sickle cell disease.
Bolarinwa AB, Oduwole O, Okebe J, Ogbenna AA, Otokiti OE, Olatinwo AT
Cochrane Database Syst Rev 2024 May 22;5(5):CD013590. doi: 10.1002/14651858.CD013590.pub2. PMID: 38775255Free PMC Article
Comparison of the fenestrated and non-fenestrated Fontan procedures: A meta-analysis.
Li D, Li M, Zhou X, An Q
Medicine (Baltimore) 2019 Jul;98(29):e16554. doi: 10.1097/MD.0000000000016554. PMID: 31335738Free PMC Article
Pulse oximetry screening for critical congenital heart defects.
Plana MN, Zamora J, Suresh G, Fernandez-Pineda L, Thangaratinam S, Ewer AK
Cochrane Database Syst Rev 2018 Mar 1;3(3):CD011912. doi: 10.1002/14651858.CD011912.pub2. PMID: 29494750Free PMC Article
Peri-operative chest physiotherapy for paediatric cardiac patients: a systematic review and meta-analysis.
Beningfield A, Jones A
Physiotherapy 2018 Sep;104(3):251-263. Epub 2017 Dec 5 doi: 10.1016/j.physio.2017.08.011. PMID: 29361296
Does This Child Have Pneumonia?: The Rational Clinical Examination Systematic Review.
Shah SN, Bachur RG, Simel DL, Neuman MI
JAMA 2017 Aug 1;318(5):462-471. doi: 10.1001/jama.2017.9039. PMID: 28763554

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