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Digestive System Hemangioma

MedGen UID:
66794
•Concept ID:
C0239707
•
Finding
Synonyms: Angioma of Digestive System; Angioma of Gastrointestinal System; Angioma of the Digestive System; Angioma of the Gastrointestinal System; Digestive Angioma; Digestive Hemangioma; Digestive System Angioma; Gastrointestinal Angioma; Gastrointestinal Hemangioma; Gastrointestinal System Angioma; Gastrointestinal System Hemangioma; Hemangioma of Digestive System; Hemangioma of Gastrointestinal System; Hemangioma of the Digestive System; Hemangioma of the Gastrointestinal System

Definition

A hemangioma arising from any part of the digestive system. [from NCI]

Professional guidelines

PubMed

Benign liver tumours: understanding molecular physiology to adapt clinical management.
Nault JC, Paradis V, Ronot M, Zucman-Rossi J
Nat Rev Gastroenterol Hepatol 2022 Nov;19(11):703-716. Epub 2022 Jul 14 doi: 10.1038/s41575-022-00643-5. PMID: 35835851
Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment.
Rosenberg A, Agulnik M
Curr Treat Options Oncol 2018 Mar 15;19(4):19. doi: 10.1007/s11864-018-0536-y. PMID: 29546487
ACG clinical guideline: the diagnosis and management of focal liver lesions.
Marrero JA, Ahn J, Rajender Reddy K; Americal College of Gastroenterology
Am J Gastroenterol 2014 Sep;109(9):1328-47; quiz 1348. Epub 2014 Aug 19 doi: 10.1038/ajg.2014.213. PMID: 25135008

Recent clinical studies

Etiology

Benign liver tumours: understanding molecular physiology to adapt clinical management.
Nault JC, Paradis V, Ronot M, Zucman-Rossi J
Nat Rev Gastroenterol Hepatol 2022 Nov;19(11):703-716. Epub 2022 Jul 14 doi: 10.1038/s41575-022-00643-5. PMID: 35835851
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands.
Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980Free PMC Article
Incidental Liver Findings on Cross-sectional Imaging.
Searleman AC, Aganovic L, Santillan CS
Radiol Clin North Am 2021 Jul;59(4):569-590. doi: 10.1016/j.rcl.2021.03.007. PMID: 34053606
Benign oral mucosal lesions: Clinical and pathological findings.
Maymone MBC, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, Maymone AC, Kesecker J, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):43-56. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.061. PMID: 30447312
The ins and outs of liver imaging.
O'Neill EK, Cogley JR, Miller FH
Clin Liver Dis 2015 Feb;19(1):99-121. Epub 2014 Oct 29 doi: 10.1016/j.cld.2014.09.006. PMID: 25454299

Diagnosis

Giant Hepatic Hemangioma.
Feng ZH, Chen XF, Jiang JS
Clin Gastroenterol Hepatol 2024 Oct;22(10):A24-A25. Epub 2024 May 8 doi: 10.1016/j.cgh.2024.04.024. PMID: 38723979
Intra-abdominal epithelioid angiosarcoma.
Torres Jurado MJ, López Sánchez J, Quiñones Sampedro JE, Muñoz Bellvís L
Rev Esp Enferm Dig 2022 Dec;114(12):744-745. doi: 10.17235/reed.2022.8878/2022. PMID: 35607922
Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment.
Rosenberg A, Agulnik M
Curr Treat Options Oncol 2018 Mar 15;19(4):19. doi: 10.1007/s11864-018-0536-y. PMID: 29546487
Gastric epithelioid haemangioendothelioma.
Tavares AB, Almeida AG, Viveiros FA, Cidade CN, Barbosa JM
BMJ Case Rep 2011 May 10;2011 doi: 10.1136/bcr.01.2011.3791. PMID: 22696709Free PMC Article
Malignant liver tumors.
Levy AD
Clin Liver Dis 2002 Feb;6(1):147-64. doi: 10.1016/s1089-3261(03)00070-9. PMID: 11933586

Therapy

Gastrointestinal: Small bowel hemangioma with unusual endoscopic findings and complicated with obscure gastrointestinal bleeding.
Katsurahara M, Umeda Y, Yukimoto H, Shigefuku A, Nakamura M, Hamada Y, Tanaka K, Horiki N, Hayashi A, Nakagawa H
J Gastroenterol Hepatol 2023 Sep;38(9):1455. Epub 2023 Feb 7 doi: 10.1111/jgh.16109. PMID: 36751046
Hepatic complications of oral contraceptive pills and estrogen on MRI: Controversies and update - Adenoma and beyond.
Ponnatapura J, Kielar A, Burke LMB, Lockhart ME, Abualruz AR, Tappouni R, Lalwani N
Magn Reson Imaging 2019 Jul;60:110-121. Epub 2019 Apr 19 doi: 10.1016/j.mri.2019.04.010. PMID: 31009688
Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment.
Rosenberg A, Agulnik M
Curr Treat Options Oncol 2018 Mar 15;19(4):19. doi: 10.1007/s11864-018-0536-y. PMID: 29546487
Liver transplantation for malignancies.
Eghtesad B, Aucejo F
J Gastrointest Cancer 2014 Sep;45(3):353-62. doi: 10.1007/s12029-014-9590-2. PMID: 24604263
Focal nodular hyperplasia.
Vilgrain V
Eur J Radiol 2006 May;58(2):236-45. Epub 2006 Jan 18 doi: 10.1016/j.ejrad.2005.11.043. PMID: 16414229

Prognosis

Benign liver tumours: understanding molecular physiology to adapt clinical management.
Nault JC, Paradis V, Ronot M, Zucman-Rossi J
Nat Rev Gastroenterol Hepatol 2022 Nov;19(11):703-716. Epub 2022 Jul 14 doi: 10.1038/s41575-022-00643-5. PMID: 35835851
Hepatic complications of oral contraceptive pills and estrogen on MRI: Controversies and update - Adenoma and beyond.
Ponnatapura J, Kielar A, Burke LMB, Lockhart ME, Abualruz AR, Tappouni R, Lalwani N
Magn Reson Imaging 2019 Jul;60:110-121. Epub 2019 Apr 19 doi: 10.1016/j.mri.2019.04.010. PMID: 31009688
Gastric epithelioid haemangioendothelioma.
Tavares AB, Almeida AG, Viveiros FA, Cidade CN, Barbosa JM
BMJ Case Rep 2011 May 10;2011 doi: 10.1136/bcr.01.2011.3791. PMID: 22696709Free PMC Article
Benign focal liver lesions: discrimination from malignant mimickers.
Alobaidi M, Shirkhoda A
Curr Probl Diagn Radiol 2004 Nov-Dec;33(6):239-53. doi: 10.1067/j.cpradiol.2004.08.003. PMID: 15549050
Focal liver lesions: MR imaging-pathologic correlation.
Bartolozzi C, Cioni D, Donati F, Lencioni R
Eur Radiol 2001;11(8):1374-88. doi: 10.1007/s003300100845. PMID: 11519546

Clinical prediction guides

Benign liver tumours: understanding molecular physiology to adapt clinical management.
Nault JC, Paradis V, Ronot M, Zucman-Rossi J
Nat Rev Gastroenterol Hepatol 2022 Nov;19(11):703-716. Epub 2022 Jul 14 doi: 10.1038/s41575-022-00643-5. PMID: 35835851
Hepatic stellate cell activation and senescence induced by intrahepatic microbiota disturbances drive progression of liver cirrhosis toward hepatocellular carcinoma.
Liu B, Zhou Z, Jin Y, Lu J, Feng D, Peng R, Sun H, Mu X, Li C, Chen Y
J Immunother Cancer 2022 Jan;10(1) doi: 10.1136/jitc-2021-003069. PMID: 34996812Free PMC Article
Hepatic complications of oral contraceptive pills and estrogen on MRI: Controversies and update - Adenoma and beyond.
Ponnatapura J, Kielar A, Burke LMB, Lockhart ME, Abualruz AR, Tappouni R, Lalwani N
Magn Reson Imaging 2019 Jul;60:110-121. Epub 2019 Apr 19 doi: 10.1016/j.mri.2019.04.010. PMID: 31009688
Interpreting body MRI cases: classic findings in abdominal MRI.
Kania L, Guglielmo F, Mitchell D
Abdom Radiol (NY) 2018 Oct;43(10):2790-2808. doi: 10.1007/s00261-018-1551-y. PMID: 29594465
Focal liver lesions: MR imaging-pathologic correlation.
Bartolozzi C, Cioni D, Donati F, Lencioni R
Eur Radiol 2001;11(8):1374-88. doi: 10.1007/s003300100845. PMID: 11519546

Recent systematic reviews

A systematic review and meta-analysis of spectral CT to differentiate focal liver lesions.
Bhandari A, Koppen J, Wastney T, Hacking C
Clin Radiol 2023 Jun;78(6):430-436. Epub 2023 Mar 11 doi: 10.1016/j.crad.2023.02.017. PMID: 37019736
Clinical Pharmacokinetics of Metoprolol: A Systematic Review.
Zamir A, Hussain I, Ur Rehman A, Ashraf W, Imran I, Saeed H, Majeed A, Alqahtani F, Rasool MF
Clin Pharmacokinet 2022 Aug;61(8):1095-1114. Epub 2022 Jun 28 doi: 10.1007/s40262-022-01145-y. PMID: 35764772
Liver transplantation for hepatic tumors: a systematic review.
Ravaioli M, Ercolani G, Neri F, Cescon M, Stacchini G, Del Gaudio M, Cucchetti A, Pinna AD
World J Gastroenterol 2014 May 14;20(18):5345-52. doi: 10.3748/wjg.v20.i18.5345. PMID: 24833864Free PMC Article

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