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Immunoproliferative disorder

MedGen UID:
7038
•Concept ID:
C0021070
•
Neoplastic Process
Synonyms: Disorder, Immunoproliferative; Disorders, Immunoproliferative; Immunoproliferative Disorder; Immunoproliferative Disorders
SNOMED CT: Immunoproliferative disorder (127071007); Immunoproliferative disease (1162658009)
 
Monarch Initiative: MONDO:0021334

Definition

Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmunoproliferative disorder

Professional guidelines

PubMed

Multiple myeloma: EHA-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up(†).
Dimopoulos MA, Moreau P, Terpos E, Mateos MV, Zweegman S, Cook G, Delforge M, Hájek R, Schjesvold F, Cavo M, Goldschmidt H, Facon T, Einsele H, Boccadoro M, San-Miguel J, Sonneveld P, Mey U; EHA Guidelines Committee. Electronic address: [email protected]; ESMO Guidelines Committee. Electronic address: [email protected]
Ann Oncol 2021 Mar;32(3):309-322. Epub 2021 Feb 3 doi: 10.1016/j.annonc.2020.11.014. PMID: 33549387
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma.
Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos MV, Kumar S, Hillengass J, Kastritis E, Richardson P, Landgren O, Paiva B, Dispenzieri A, Weiss B, LeLeu X, Zweegman S, Lonial S, Rosinol L, Zamagni E, Jagannath S, Sezer O, Kristinsson SY, Caers J, Usmani SZ, Lahuerta JJ, Johnsen HE, Beksac M, Cavo M, Goldschmidt H, Terpos E, Kyle RA, Anderson KC, Durie BG, Miguel JF
Lancet Oncol 2014 Nov;15(12):e538-48. Epub 2014 Oct 26 doi: 10.1016/S1470-2045(14)70442-5. PMID: 25439696
Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review.
Coiffier B, Altman A, Pui CH, Younes A, Cairo MS
J Clin Oncol 2008 Jun 1;26(16):2767-78. doi: 10.1200/JCO.2007.15.0177. PMID: 18509186

Recent clinical studies

Etiology

The wide spectrum of cryoglobulinemic vasculitis and an overview of therapeutic advancements.
Dammacco F, Lauletta G, Vacca A
Clin Exp Med 2023 Jun;23(2):255-272. Epub 2022 Mar 28 doi: 10.1007/s10238-022-00808-1. PMID: 35348938Free PMC Article
Maculopathy in Patients with Monoclonal Gammopathy of Undetermined Significance.
Smith SJ, Johnson MW, Ober MD, Comer GM, Smith BD
Ophthalmol Retina 2020 Mar;4(3):300-309. Epub 2019 Oct 9 doi: 10.1016/j.oret.2019.09.018. PMID: 31753810
Falsely low LDL-cholesterol concentrations and artifactual undetectable HDL-cholesterol measured by direct methods in a patient with monoclonal paraprotein.
Tsai LY, Tsai SM, Lee SC, Liu SF
Clin Chim Acta 2005 Aug;358(1-2):192-5. doi: 10.1016/j.cccn.2005.02.008. PMID: 15896728

Diagnosis

The wide spectrum of cryoglobulinemic vasculitis and an overview of therapeutic advancements.
Dammacco F, Lauletta G, Vacca A
Clin Exp Med 2023 Jun;23(2):255-272. Epub 2022 Mar 28 doi: 10.1007/s10238-022-00808-1. PMID: 35348938Free PMC Article
Maculopathy in Patients with Monoclonal Gammopathy of Undetermined Significance.
Smith SJ, Johnson MW, Ober MD, Comer GM, Smith BD
Ophthalmol Retina 2020 Mar;4(3):300-309. Epub 2019 Oct 9 doi: 10.1016/j.oret.2019.09.018. PMID: 31753810
Lymphomatoid granulomatosis in a 23-year-old man--cytological and histological typing and rapid response to steroid and cyclophosphamide combination therapy.
Rakusić N, Krmpotić D, Hećimović A, Boras Z, Vrabec-Branica B, Dzebro S, Rakusić N, Resković T, Rakusić N
Coll Antropol 2010 Mar;34(1):279-83. PMID: 20437644
High incidence of monoclonal proteins in the serum and urine of chronic lymphocytic leukemia patients.
Deegan MJ, Abraham JP, Sawdyk M, Van Slyck EJ
Blood 1984 Dec;64(6):1207-11. PMID: 6437461
Immunoblastic lymphadenopathy and asbestosis.
Maguire FW, Mills RC, Parker FP
Cancer 1981 Feb 15;47(4):791-7. doi: 10.1002/1097-0142(19810215)47:4<791::aid-cncr2820470426>3.0.co;2-6. PMID: 7226027

Therapy

The wide spectrum of cryoglobulinemic vasculitis and an overview of therapeutic advancements.
Dammacco F, Lauletta G, Vacca A
Clin Exp Med 2023 Jun;23(2):255-272. Epub 2022 Mar 28 doi: 10.1007/s10238-022-00808-1. PMID: 35348938Free PMC Article
Lymphomatoid granulomatosis in a 23-year-old man--cytological and histological typing and rapid response to steroid and cyclophosphamide combination therapy.
Rakusić N, Krmpotić D, Hećimović A, Boras Z, Vrabec-Branica B, Dzebro S, Rakusić N, Resković T, Rakusić N
Coll Antropol 2010 Mar;34(1):279-83. PMID: 20437644
Immunosuppression and the rheumatic diseases.
Denman AM
Ann Rheum Dis 1982;41 Suppl 1(Suppl 1):3-8. doi: 10.1136/ard.41.suppl_1.3. PMID: 6978108Free PMC Article

Prognosis

Maculopathy in Patients with Monoclonal Gammopathy of Undetermined Significance.
Smith SJ, Johnson MW, Ober MD, Comer GM, Smith BD
Ophthalmol Retina 2020 Mar;4(3):300-309. Epub 2019 Oct 9 doi: 10.1016/j.oret.2019.09.018. PMID: 31753810
Pulmonary cystic disorder related to light chain deposition disease.
Colombat M, Stern M, Groussard O, Droz D, Brauner M, Valeyre D, Mal H, Taillé C, Monnet I, Fournier M, Herson S, Danel C
Am J Respir Crit Care Med 2006 Apr 1;173(7):777-80. Epub 2006 Jan 6 doi: 10.1164/rccm.200510-1620CR. PMID: 16399989
Waldenström's macroglobulinemia: a clinicopathologic study of 22 cases.
Andriko JA, Aguilera NS, Chu WS, Nandedkar MA, Cotelingam JD
Cancer 1997 Nov 15;80(10):1926-35. PMID: 9366295
Cutaneous manifestations of angioimmunoblastic lymphadenopathy.
Bernstein JE, Soltani K, Lorincz AL
J Am Acad Dermatol 1979 Sep;1(3):227-32. doi: 10.1016/s0190-9622(79)70014-4. PMID: 512072
The pathologic anatomy of alpha chain disease.
Rappaport H
Hamatol Bluttransfus 1976;18:377-82. PMID: 823078

Clinical prediction guides

Light chain deposition disease involving the airways: diagnosis by fibreoptic bronchoscopy.
Colombat M, Gounant V, Mal H, Callard P, Milleron B
Eur Respir J 2007 May;29(5):1057-60. doi: 10.1183/09031936.00134406. PMID: 17470625
Falsely low LDL-cholesterol concentrations and artifactual undetectable HDL-cholesterol measured by direct methods in a patient with monoclonal paraprotein.
Tsai LY, Tsai SM, Lee SC, Liu SF
Clin Chim Acta 2005 Aug;358(1-2):192-5. doi: 10.1016/j.cccn.2005.02.008. PMID: 15896728
Waldenström's macroglobulinemia: a clinicopathologic study of 22 cases.
Andriko JA, Aguilera NS, Chu WS, Nandedkar MA, Cotelingam JD
Cancer 1997 Nov 15;80(10):1926-35. PMID: 9366295
High incidence of monoclonal proteins in the serum and urine of chronic lymphocytic leukemia patients.
Deegan MJ, Abraham JP, Sawdyk M, Van Slyck EJ
Blood 1984 Dec;64(6):1207-11. PMID: 6437461

Supplemental Content

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