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Renal diverticulum

MedGen UID:
746455
•Concept ID:
C2315541
•
Disease or Syndrome
Synonyms: Caliceal diverticulum; Calyceal diverticulum; Diverticulum of renal calyx; Pelvic diverticulum; Renal pelvic diverticulum
SNOMED CT: Diverticulum of renal calyx (433036004); Calyceal diverticulum (433036004)
 
HPO: HP:0100877

Definition

Cystic, urine-containing intrarenal cavities lined with transitional cell epithelium that communicate through a narrow channel with the collecting system. [from HPO]

Professional guidelines

PubMed

Diagnosis and Management of Renal Cystic Disease of the Newborn: Core Curriculum 2021.
Raina R, Chakraborty R, Sethi SK, Kumar D, Gibson K, Bergmann C
Am J Kidney Dis 2021 Jul;78(1):125-141. Epub 2021 Jan 6 doi: 10.1053/j.ajkd.2020.10.021. PMID: 33418012
Treatment selection for urolithiasis: percutaneous nephrolithomy, ureteroscopy, shock wave lithotripsy, and active monitoring.
Desai M, Sun Y, Buchholz N, Fuller A, Matsuda T, Matlaga B, Miller N, Bolton D, Alomar M, Ganpule A
World J Urol 2017 Sep;35(9):1395-1399. Epub 2017 Mar 16 doi: 10.1007/s00345-017-2030-8. PMID: 28303335
Management of calyceal calculi.
Cohen TD, Preminger GM
Urol Clin North Am 1997 Feb;24(1):81-96. doi: 10.1016/s0094-0143(05)70356-6. PMID: 9048854

Recent clinical studies

Etiology

Congenital anterior urethral valves and diverticula.
Rawat J, Singh S, Pandey A, Singh S
J Pediatr Surg 2023 Feb;58(2):263-265. Epub 2022 Oct 21 doi: 10.1016/j.jpedsurg.2022.10.036. PMID: 36376124
Congenital anterior urethral valves and diverticulum: A case series and association with posterior urethral valves.
Menon P, Rao KLN
J Pediatr Urol 2022 Oct;18(5):663.e1-663.e9. Epub 2022 Sep 5 doi: 10.1016/j.jpurol.2022.08.024. PMID: 36123286
Differentiation of simple renal parenchymal cyst and calyceal diverticulum.
Sahin H, Sarioglu FC, Alaygut D, Akdogan AI, Pekcevik Y
Pediatr Int 2020 May;62(5):615-623. Epub 2020 May 13 doi: 10.1111/ped.14127. PMID: 31885118
Durasphere® EXP: a non-biodegradable agent for treatment of primary Vesico-Ureteral reflux in children.
Ozkuvanci U, Donmez MI, Ozgor F, Erbin A, Pasin Ö, Muslumanoglu AY
Int Braz J Urol 2018 May-Jun;44(3):585-590. doi: 10.1590/S1677-5538.IBJU.2017.0514. PMID: 29522294Free PMC Article
The Gut in Older Patients on Peritoneal Dialysis.
Setyapranata S, Holt SG
Perit Dial Int 2015 Nov;35(6):650-4. doi: 10.3747/pdi.2014.00341. PMID: 26702007Free PMC Article

Diagnosis

Calyceal diverticulum simulating a renal tumor.
Fernandez-Alberti J, Coronil R, Iotti A, Nolazco A, Featherston M
Can J Urol 2023 Aug;30(4):11629-11632. PMID: 37633292
Congenital Anomalies of the Upper Urinary Tract: A Comprehensive Review.
Houat AP, Guimarães CTS, Takahashi MS, Rodi GP, Gasparetto TPD, Blasbalg R, Velloni FG
Radiographics 2021 Mar-Apr;41(2):462-486. Epub 2021 Jan 29 doi: 10.1148/rg.2021200078. PMID: 33513074
Diagnosis and Management of Renal Cystic Disease of the Newborn: Core Curriculum 2021.
Raina R, Chakraborty R, Sethi SK, Kumar D, Gibson K, Bergmann C
Am J Kidney Dis 2021 Jul;78(1):125-141. Epub 2021 Jan 6 doi: 10.1053/j.ajkd.2020.10.021. PMID: 33418012
Visualization of a pyelocaliceal diverticulum with [(99m)Tc]Tc-DTPA and [(99m)Tc]Tc-DMSA scintigraphy.
Orsal Ibısoglu E, Uslu H, Tarık Tatoglu M, Gungor S, Haksal C
Rev Esp Med Nucl Imagen Mol (Engl Ed) 2020 Sep-Oct;39(5):325-326. Epub 2020 Jun 27 doi: 10.1016/j.remn.2020.03.009. PMID: 32605896
Pyelocalyceal diverticula.
Michel W, Funke PJ, Tunn UW, Senge T
Int Urol Nephrol 1985;17(3):225-30. doi: 10.1007/BF02085408. PMID: 3936817

Therapy

Excreted 99m Tc-Pertechnetate in a Renal Pelvis as a Potential False Positive in a Meckel's Scan.
Lanzo SM, Pantel AR, Zhuang H
Clin Nucl Med 2023 Feb 1;48(2):173-175. Epub 2022 Jul 19 doi: 10.1097/RLU.0000000000004331. PMID: 35867987
Durasphere® EXP: a non-biodegradable agent for treatment of primary Vesico-Ureteral reflux in children.
Ozkuvanci U, Donmez MI, Ozgor F, Erbin A, Pasin Ö, Muslumanoglu AY
Int Braz J Urol 2018 May-Jun;44(3):585-590. doi: 10.1590/S1677-5538.IBJU.2017.0514. PMID: 29522294Free PMC Article
Bilateral Obstructive Uropathy Caused by Congenital Bladder Diverticulum Presenting as Hypertensive Retinopathy.
Kim S, Park SH, Kim DY, Yun SJ, Lee OJ, Han HS
J Korean Med Sci 2018 Feb 19;33(8):e54. doi: 10.3346/jkms.2018.33.e54. PMID: 29441752Free PMC Article
The Gut in Older Patients on Peritoneal Dialysis.
Setyapranata S, Holt SG
Perit Dial Int 2015 Nov;35(6):650-4. doi: 10.3747/pdi.2014.00341. PMID: 26702007Free PMC Article
Intestinal perforation due to fecal impaction after renal transplantation.
Aguilo JJ, Zincke H, Woods JE, Buckingham JM
J Urol 1976 Aug;116(2):153-5. doi: 10.1016/s0022-5347(17)58726-1. PMID: 781315

Prognosis

Congenital anterior urethral valves and diverticulum: A case series and association with posterior urethral valves.
Menon P, Rao KLN
J Pediatr Urol 2022 Oct;18(5):663.e1-663.e9. Epub 2022 Sep 5 doi: 10.1016/j.jpurol.2022.08.024. PMID: 36123286
Calyceal diverticula: Clinical, radiological and histopathological findings of an uncommon entity with presumed congenital origin.
Srivastava P, Satturwar S, Bastacky S, Dhir R, Reyes-Múgica M, Beasley HS, Quiroga-Garza GM
Ann Diagn Pathol 2022 Jun;58:151932. Epub 2022 Mar 4 doi: 10.1016/j.anndiagpath.2022.151932. PMID: 35276547
Urothelial metaplasia of the seminal vesicle and ejaculatory duct associated with crossed-fused renal ectopia and Hutch diverticulum of the bladder.
Chezar K, Gotto G, Medlicott S, Trpkov K
Can J Urol 2018 Jun;25(3):9360-9362. PMID: 29900826
The Gut in Older Patients on Peritoneal Dialysis.
Setyapranata S, Holt SG
Perit Dial Int 2015 Nov;35(6):650-4. doi: 10.3747/pdi.2014.00341. PMID: 26702007Free PMC Article
Colon perforation in renal transplant patients.
Guice K, Rattazzi LC, Marchioro TL
Am J Surg 1979 Jul;138(1):43-8. doi: 10.1016/0002-9610(79)90240-x. PMID: 380376

Clinical prediction guides

Urothelial metaplasia of the seminal vesicle and ejaculatory duct associated with crossed-fused renal ectopia and Hutch diverticulum of the bladder.
Chezar K, Gotto G, Medlicott S, Trpkov K
Can J Urol 2018 Jun;25(3):9360-9362. PMID: 29900826
Nephrogenic adenoma of the urinary tract: A 6-year single center experience.
Turcan D, Acikalin MF, Yilmaz E, Canaz F, Arik D
Pathol Res Pract 2017 Jul;213(7):831-835. Epub 2017 Mar 25 doi: 10.1016/j.prp.2017.03.001. PMID: 28554748
Risk factors associated with recurrent hemorrhage after the initial improvement of colonic diverticular bleeding.
Nishikawa H, Maruo T, Tsumura T, Sekikawa A, Kanesaka T, Osaki Y
Acta Gastroenterol Belg 2013 Mar;76(1):20-4. PMID: 23650778
Prevalence of diverticulosis and incidence of bowel perforation after kidney transplantation in patients with polycystic kidney disease.
Domínguez Fernández E, Albrecht KH, Heemann U, Kohnle M, Erhard J, Stöblen F, Eigler FW
Transpl Int 1998;11(1):28-31. doi: 10.1007/s001470050098. PMID: 9503551
Hepatobiliary clearance of intravenous Tc-99m pertechnetate.
Stern SS, Leslie WD, Dupont JO, Peterdy AE, Billinghurst MW, Abrams DN
Clin Nucl Med 1995 Nov;20(11):962-4. doi: 10.1097/00003072-199511000-00002. PMID: 8565374

Recent systematic reviews

Mesalazine for People with Diverticular Disease: A Systematic Review of Randomized Controlled Trials.
Iannone A, Ruospo M, Wong G, Barone M, Principi M, Di Leo A, Strippoli GFM
Can J Gastroenterol Hepatol 2018;2018:5437135. Epub 2018 Sep 16 doi: 10.1155/2018/5437135. PMID: 30320044Free PMC Article
Predicting renal outcomes in children with anterior urethral valves: a systematic review.
Routh JC, McGee SM, Ashley RA, Reinberg Y, Vandersteen DR
J Urol 2010 Oct;184(4 Suppl):1615-9. Epub 2010 Aug 21 doi: 10.1016/j.juro.2010.03.119. PMID: 20728183

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