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Thrombosis of blood vessel

MedGen UID:
750462
•Concept ID:
C2586211
•
Pathologic Function
Synonym: Vascular Thrombosis
SNOMED CT: Thrombosis of blood vessel (439129009)

Definition

The formation of a blood clot in the lumen of a vessel; causes include coagulation disorders, and vascular endothelial injury. [from NCI]

Professional guidelines

PubMed

Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association.
Saposnik G, Bushnell C, Coutinho JM, Field TS, Furie KL, Galadanci N, Kam W, Kirkham FC, McNair ND, Singhal AB, Thijs V, Yang VXD; American Heart Association Stroke Council; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; Council on Cardiovascular and Stroke Nursing; and Council on Hypertension
Stroke 2024 Mar;55(3):e77-e90. Epub 2024 Jan 29 doi: 10.1161/STR.0000000000000456. PMID: 38284265
Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis.
Intagliata NM, Caldwell SH, Tripodi A
Gastroenterology 2019 May;156(6):1582-1599.e1. Epub 2019 Feb 13 doi: 10.1053/j.gastro.2019.01.265. PMID: 30771355
Antithrombotic therapy in neonates and children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Monagle P, Chan AKC, Goldenberg NA, Ichord RN, Journeycake JM, Nowak-Göttl U, Vesely SK
Chest 2012 Feb;141(2 Suppl):e737S-e801S. doi: 10.1378/chest.11-2308. PMID: 22315277Free PMC Article

Recent clinical studies

Etiology

Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis.
Intagliata NM, Caldwell SH, Tripodi A
Gastroenterology 2019 May;156(6):1582-1599.e1. Epub 2019 Feb 13 doi: 10.1053/j.gastro.2019.01.265. PMID: 30771355
Thromboinflammation and Vascular Dysfunction.
Karbach S, Lagrange J, Wenzel P
Hamostaseologie 2019 Jun;39(2):180-187. Epub 2018 Dec 4 doi: 10.1055/s-0038-1676130. PMID: 30513535
Pathophysiology of venous thrombosis.
López JA, Chen J
Thromb Res 2009;123 Suppl 4:S30-4. doi: 10.1016/S0049-3848(09)70140-9. PMID: 19303501
The pathophysiology of cigarette smoking and cardiovascular disease: an update.
Ambrose JA, Barua RS
J Am Coll Cardiol 2004 May 19;43(10):1731-7. doi: 10.1016/j.jacc.2003.12.047. PMID: 15145091
Hypercoagulation and thrombosis.
Penner JA
Med Clin North Am 1980 Jul;64(4):743-59. doi: 10.1016/s0025-7125(16)31591-7. PMID: 6772892

Diagnosis

Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis.
Intagliata NM, Caldwell SH, Tripodi A
Gastroenterology 2019 May;156(6):1582-1599.e1. Epub 2019 Feb 13 doi: 10.1053/j.gastro.2019.01.265. PMID: 30771355
Venous thrombosis in unusual sites: A practical review for the hematologist.
Shatzel JJ, O'Donnell M, Olson SR, Kearney MR, Daughety MM, Hum J, Nguyen KP, DeLoughery TG
Eur J Haematol 2019 Jan;102(1):53-62. Epub 2018 Oct 29 doi: 10.1111/ejh.13177. PMID: 30267448
Endothelium and haemostasis.
Aird WC
Hamostaseologie 2015;35(1):11-6. doi: 10.5482/HAMO-14-11-0075. PMID: 25666572
Mesenteric ischemia.
Bobadilla JL
Surg Clin North Am 2013 Aug;93(4):925-40, ix. Epub 2013 May 16 doi: 10.1016/j.suc.2013.04.002. PMID: 23885938
Hypercoagulation and thrombosis.
Penner JA
Med Clin North Am 1980 Jul;64(4):743-59. doi: 10.1016/s0025-7125(16)31591-7. PMID: 6772892

Therapy

Targeting cysteinyl-leukotrienes in abdominal aortic aneurysm.
Araújo AC, Tang X, Haeggström JZ
Prostaglandins Other Lipid Mediat 2018 Nov;139:24-28. Epub 2018 Sep 21 doi: 10.1016/j.prostaglandins.2018.09.007. PMID: 30248405
Open Surgical Management of Deep Venous Occlusive Disease.
Kiguchi MM, Abramowitz SD
Tech Vasc Interv Radiol 2018 Jun;21(2):117-122. Epub 2018 Mar 8 doi: 10.1053/j.tvir.2018.03.008. PMID: 29784120
Thrombosis and von Willebrand Factor.
Shahidi M
Adv Exp Med Biol 2017;906:285-306. doi: 10.1007/5584_2016_122. PMID: 27628010
Thrombosis in vasculitic disorders-clinical manifestations, pathogenesis and management.
Katz OB, Brenner B, Horowitz NA
Thromb Res 2015 Sep;136(3):504-12. Epub 2015 Jul 15 doi: 10.1016/j.thromres.2015.07.016. PMID: 26220271
Prostaglandin I2 (prostacyclin).
Kelton JG, Blajchman MA
Can Med Assoc J 1980 Jan 26;122(2):175-9. PMID: 6988063Free PMC Article

Prognosis

Current knowledge and management of portal vein thrombosis in cirrhosis.
Senzolo M, Garcia-Tsao G, García-Pagán JC
J Hepatol 2021 Aug;75(2):442-453. Epub 2021 Apr 27 doi: 10.1016/j.jhep.2021.04.029. PMID: 33930474
Budd-Chiari syndrome/hepatic venous outflow tract obstruction.
Valla DC
Hepatol Int 2018 Feb;12(Suppl 1):168-180. Epub 2017 Jul 6 doi: 10.1007/s12072-017-9810-5. PMID: 28685257
Modeling thrombus formation and growth.
Hosseinzadegan H, Tafti DK
Biotechnol Bioeng 2017 Oct;114(10):2154-2172. Epub 2017 Jun 26 doi: 10.1002/bit.26343. PMID: 28542700
Thrombosis and von Willebrand Factor.
Shahidi M
Adv Exp Med Biol 2017;906:285-306. doi: 10.1007/5584_2016_122. PMID: 27628010
Clinical implications of platelet-vessel interaction.
Mangiacapra F, Barbato E
J Cardiovasc Transl Res 2013 Jun;6(3):310-5. Epub 2012 Dec 28 doi: 10.1007/s12265-012-9441-0. PMID: 23271646

Clinical prediction guides

Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis.
Intagliata NM, Caldwell SH, Tripodi A
Gastroenterology 2019 May;156(6):1582-1599.e1. Epub 2019 Feb 13 doi: 10.1053/j.gastro.2019.01.265. PMID: 30771355
Modeling thrombus formation and growth.
Hosseinzadegan H, Tafti DK
Biotechnol Bioeng 2017 Oct;114(10):2154-2172. Epub 2017 Jun 26 doi: 10.1002/bit.26343. PMID: 28542700
Transplant Renal Vein Thrombosis.
El Zorkany K, Bridson JM, Sharma A, Halawa A
Exp Clin Transplant 2017 Apr;15(2):123-129. doi: 10.6002/ect.2016.0060. PMID: 28338457
Thrombosis and von Willebrand Factor.
Shahidi M
Adv Exp Med Biol 2017;906:285-306. doi: 10.1007/5584_2016_122. PMID: 27628010
Clinical access assessment.
Tessitore N, Bedogna V, Verlato G, Poli A
J Vasc Access 2014;15 Suppl 7:S20-7. Epub 2014 Apr 12 doi: 10.5301/jva.5000242. PMID: 24817450

Recent systematic reviews

The 2023 Society for Vascular Surgery, American Venous Forum, and American Vein and Lymphatic Society clinical practice guidelines for the management of varicose veins of the lower extremities. Part II: Endorsed by the Society of Interventional Radiology and the Society for Vascular Medicine.
Gloviczki P, Lawrence PF, Wasan SM, Meissner MH, Almeida J, Brown KR, Bush RL, Di Iorio M, Fish J, Fukaya E, Gloviczki ML, Hingorani A, Jayaraj A, Kolluri R, Murad MH, Obi AT, Ozsvath KJ, Singh MJ, Vayuvegula S, Welch HJ
J Vasc Surg Venous Lymphat Disord 2024 Jan;12(1):101670. Epub 2023 Aug 29 doi: 10.1016/j.jvsv.2023.08.011. PMID: 37652254Free PMC Article
Epidemiology of portal vein thrombosis in liver cirrhosis: A systematic review and meta-analysis.
Pan J, Wang L, Gao F, An Y, Yin Y, Guo X, Nery FG, Yoshida EM, Qi X
Eur J Intern Med 2022 Oct;104:21-32. Epub 2022 Jun 7 doi: 10.1016/j.ejim.2022.05.032. PMID: 35688747
COVID-19 Vaccine-Related Thrombosis: A Systematic Review and Exploratory Analysis.
Bilotta C, Perrone G, Adelfio V, Spatola GF, Uzzo ML, Argo A, Zerbo S
Front Immunol 2021;12:729251. Epub 2021 Nov 29 doi: 10.3389/fimmu.2021.729251. PMID: 34912330Free PMC Article
Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.
Acosta S, Salim S
Scand J Surg 2021 Jun;110(2):123-129. Epub 2020 Oct 29 doi: 10.1177/1457496920969084. PMID: 33118463Free PMC Article
Acute Aortic Dissection and Intramural Hematoma: A Systematic Review.
Mussa FF, Horton JD, Moridzadeh R, Nicholson J, Trimarchi S, Eagle KA
JAMA 2016 Aug 16;316(7):754-63. doi: 10.1001/jama.2016.10026. PMID: 27533160

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