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Autoimmune pancreatitis

MedGen UID:
750633
Concept ID:
C2609129
Disease or Syndrome
Synonyms: Autoimmune Pancreatitides; Autoimmune Pancreatitis; Pancreatitis, Autoimmune
SNOMED CT: Autoimmune pancreatitis (448542008)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0015175
Orphanet: ORPHA103919

Definition

A rare pancreatic disease characterized by chronic non-alcoholic pancreatitis that presents with abdominal pain, steatorrhea, obstructive jaundice and responds well to steroid therapy and is seen in two subforms: type which affects elderly males, involves other organs and has increased immunoglobin G4 (IgG4) levels and type 2 which affects both sexes equally but presents at a younger age and has no other organ involvement or increased IgG4 levels. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAutoimmune pancreatitis
Follow this link to review classifications for Autoimmune pancreatitis in Orphanet.

Professional guidelines

PubMed

Nista EC, De Lucia SS, Manilla V, Schepis T, Pellegrino A, Ojetti V, Pignataro G, Zileri Dal Verme L, Franceschi F, Gasbarrini A, Candelli M
Int J Mol Sci 2022 Oct 21;23(20) doi: 10.3390/ijms232012667. PMID: 36293522Free PMC Article
Löhr JM, Beuers U, Vujasinovic M, Alvaro D, Frøkjær JB, Buttgereit F, Capurso G, Culver EL, de-Madaria E, Della-Torre E, Detlefsen S, Dominguez-Muñoz E, Czubkowski P, Ewald N, Frulloni L, Gubergrits N, Duman DG, Hackert T, Iglesias-Garcia J, Kartalis N, Laghi A, Lammert F, Lindgren F, Okhlobystin A, Oracz G, Parniczky A, Mucelli RMP, Rebours V, Rosendahl J, Schleinitz N, Schneider A, van Bommel EF, Verbeke CS, Vullierme MP, Witt H; UEG guideline working group
United European Gastroenterol J 2020 Jul;8(6):637-666. Epub 2020 Jun 18 doi: 10.1177/2050640620934911. PMID: 32552502Free PMC Article
Okazaki K, Chari ST, Frulloni L, Lerch MM, Kamisawa T, Kawa S, Kim MH, Lévy P, Masamune A, Webster G, Shimosegawa T
Pancreatology 2017 Jan-Feb;17(1):1-6. Epub 2016 Dec 12 doi: 10.1016/j.pan.2016.12.003. PMID: 28027896

Recent clinical studies

Etiology

Cohen RZ, Freeman AJ
Pediatr Clin North Am 2021 Dec;68(6):1273-1291. doi: 10.1016/j.pcl.2021.07.012. PMID: 34736589
Schima W, Böhm G, Rösch CS, Klaus A, Függer R, Kopf H
Cancer Imaging 2020 Jul 23;20(1):52. doi: 10.1186/s40644-020-00324-z. PMID: 32703312Free PMC Article
Majumder S, Takahashi N, Chari ST
Dig Dis Sci 2017 Jul;62(7):1762-1769. Epub 2017 Apr 1 doi: 10.1007/s10620-017-4541-y. PMID: 28365915
Stram M, Liu S, Singhi AD
Surg Pathol Clin 2016 Dec;9(4):643-659. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.008. PMID: 27926364
Kubo K, Yamamoto K
Int J Rheum Dis 2016 Aug;19(8):747-62. Epub 2015 Aug 10 doi: 10.1111/1756-185X.12586. PMID: 26259069

Diagnosis

Gallo C, Dispinzieri G, Zucchini N, Invernizzi P, Massironi S
World J Gastroenterol 2024 Feb 28;30(8):817-832. doi: 10.3748/wjg.v30.i8.817. PMID: 38516247Free PMC Article
Nista EC, De Lucia SS, Manilla V, Schepis T, Pellegrino A, Ojetti V, Pignataro G, Zileri Dal Verme L, Franceschi F, Gasbarrini A, Candelli M
Int J Mol Sci 2022 Oct 21;23(20) doi: 10.3390/ijms232012667. PMID: 36293522Free PMC Article
Cohen RZ, Freeman AJ
Pediatr Clin North Am 2021 Dec;68(6):1273-1291. doi: 10.1016/j.pcl.2021.07.012. PMID: 34736589
Sánchez-Oro R, Alonso-Muñoz EM, Martí Romero L
Gastroenterol Hepatol 2019 Dec;42(10):638-647. Epub 2019 Nov 11 doi: 10.1016/j.gastrohep.2019.08.009. PMID: 31722794
Zhao YX, Lü H
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2016 Dec 20;38(6):731-734. doi: 10.3881/j.issn.1000-503X.2016.06.018. PMID: 28065243

Therapy

Nista EC, De Lucia SS, Manilla V, Schepis T, Pellegrino A, Ojetti V, Pignataro G, Zileri Dal Verme L, Franceschi F, Gasbarrini A, Candelli M
Int J Mol Sci 2022 Oct 21;23(20) doi: 10.3390/ijms232012667. PMID: 36293522Free PMC Article
Katz G, Stone JH
Annu Rev Med 2022 Jan 27;73:545-562. Epub 2021 Oct 20 doi: 10.1146/annurev-med-050219-034449. PMID: 34669430
Nagpal SJS, Sharma A, Chari ST
Am J Gastroenterol 2018 Sep;113(9):1301. Epub 2018 Jun 18 doi: 10.1038/s41395-018-0146-0. PMID: 29910463
Majumder S, Takahashi N, Chari ST
Dig Dis Sci 2017 Jul;62(7):1762-1769. Epub 2017 Apr 1 doi: 10.1007/s10620-017-4541-y. PMID: 28365915
Kubo K, Yamamoto K
Int J Rheum Dis 2016 Aug;19(8):747-62. Epub 2015 Aug 10 doi: 10.1111/1756-185X.12586. PMID: 26259069

Prognosis

Schima W, Böhm G, Rösch CS, Klaus A, Függer R, Kopf H
Cancer Imaging 2020 Jul 23;20(1):52. doi: 10.1186/s40644-020-00324-z. PMID: 32703312Free PMC Article
Okamoto A, Watanabe T, Kamata K, Minaga K, Kudo M
Intern Med 2019 Jun 1;58(11):1533-1539. Epub 2019 Feb 1 doi: 10.2169/internalmedicine.2210-18. PMID: 30713326Free PMC Article
Nagpal SJS, Sharma A, Chari ST
Am J Gastroenterol 2018 Sep;113(9):1301. Epub 2018 Jun 18 doi: 10.1038/s41395-018-0146-0. PMID: 29910463
Kubo K, Yamamoto K
Int J Rheum Dis 2016 Aug;19(8):747-62. Epub 2015 Aug 10 doi: 10.1111/1756-185X.12586. PMID: 26259069
Sugumar A, Chari ST
J Gastroenterol Hepatol 2011 Sep;26(9):1368-73. doi: 10.1111/j.1440-1746.2011.06843.x. PMID: 21884246

Clinical prediction guides

Sohail Z, Shaikh H, Iqbal N, Parkash O
J Pak Med Assoc 2024 May;74(5):953-958. doi: 10.47391/JPMA.9280. PMID: 38783446
Okazaki K, Kawa S, Kamisawa T, Ikeura T, Itoi T, Ito T, Inui K, Irisawa A, Uchida K, Ohara H, Kubota K, Kodama Y, Shimizu K, Tonozuka R, Nakazawa T, Nishino T, Notohara K, Fujinaga Y, Masamune A, Yamamoto H, Watanabe T, Nishiyama T, Kawano M, Shiratori K, Shimosegawa T, Takeyama Y; Members of the Research Committee for IgG4-related Disease supported by the Ministry of Health, Labour, Welfare of Japan, Japan Pancreas Society
J Gastroenterol 2022 Apr;57(4):225-245. Epub 2022 Feb 22 doi: 10.1007/s00535-022-01857-9. PMID: 35192048Free PMC Article
Nakazawa T, Shimizu S, Naitoh I
Semin Liver Dis 2016 Aug;36(3):216-28. Epub 2016 Jul 28 doi: 10.1055/s-0036-1584321. PMID: 27466792
Kubo K, Yamamoto K
Int J Rheum Dis 2016 Aug;19(8):747-62. Epub 2015 Aug 10 doi: 10.1111/1756-185X.12586. PMID: 26259069
Sugumar A, Chari ST
J Gastroenterol Hepatol 2011 Sep;26(9):1368-73. doi: 10.1111/j.1440-1746.2011.06843.x. PMID: 21884246

Recent systematic reviews

Yoon SB, Jeon TY, Moon SH, Shin DW, Lee SM, Choi MH, Min JH, Kim MJ
Eur Radiol 2023 Dec;33(12):9010-9021. Epub 2023 Jul 19 doi: 10.1007/s00330-023-09959-5. PMID: 37466708
Haghbin H, Chuang J, Fatima R, Zakirkhodjaev N, Lee-Smith W, Aziz M
Dig Dis Sci 2022 Jul;67(7):3252-3264. Epub 2021 Jul 23 doi: 10.1007/s10620-021-07179-9. PMID: 34297267
Masaki Y, Nakase H, Tsuji Y, Nojima M, Shimizu K, Mizuno N, Ikeura T, Uchida K, Ido A, Kodama Y, Seno H, Okazaki K, Nakamura S, Masamune A
J Gastroenterol 2021 Oct;56(10):869-880. Epub 2021 Aug 24 doi: 10.1007/s00535-021-01817-9. PMID: 34426870Free PMC Article
Lian MJ, Liu S, Wu GY, Liu SY
Clin Res Hepatol Gastroenterol 2016 Feb;40(1):99-109. Epub 2015 Jul 6 doi: 10.1016/j.clinre.2015.06.002. PMID: 26160477
Meng Q, Xin L, Liu W, Lin H, Tian B, Wang L, Li Z
PLoS One 2015;10(6):e0130466. Epub 2015 Jun 25 doi: 10.1371/journal.pone.0130466. PMID: 26110658Free PMC Article

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