U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Haemophilus meningitis

MedGen UID:
7535
•Concept ID:
C0025292
•
Disease or Syndrome
Synonyms: Haemophilus Meningitides; Haemophilus Meningitis; Hemophilus Meningitides; Hemophilus Meningitis; Meningitides, Haemophilus; Meningitides, Hemophilus; Meningitis, Haemophilus; Meningitis, Hemophilus
SNOMED CT: Haemophilus meningitis (192643004)
 
Monarch Initiative: MONDO:0000889

Definition

Infections of the nervous system caused by bacteria of the genus haemophilus, and marked by prominent inflammation of the meninges. haemophilus influenzae type B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHaemophilus meningitis

Professional guidelines

PubMed

Management of bacterial menigitis in 2016.
Javouhey E
Bull Acad Natl Med 2016 Jan;200(1):99-111. PMID: 29889417
Adjunctive dexamethasone treatment in acute bacterial meningitis.
Chaudhuri A
Lancet Neurol 2004 Jan;3(1):54-62. doi: 10.1016/s1474-4422(03)00623-9. PMID: 14693112
H. INFLUENZAE MENINGITIS: A CONTROLLED STUDY OF TREATMENT WITH AMPICILLIN.
THRUPP LD, LEEDOM JM, IVLER D, WEHRLE PF, BROWN JF, MATHIES AW, PORTNOY B
Postgrad Med J 1964 Dec;40(Suppl):SUPPL:119-26. doi: 10.1136/pgmj.40.suppl.119. PMID: 14246826Free PMC Article

Recent clinical studies

Etiology

Risk factors for community-acquired bacterial meningitis.
Lundbo LF, Benfield T
Infect Dis (Lond) 2017 Jun;49(6):433-444. doi: 10.1080/23744235.2017.1285046. PMID: 28301990
New diagnostic and therapeutic options in bacterial meningitis in infants and children.
Kim KS
Minerva Pediatr 2009 Oct;61(5):531-48. PMID: 19794379
Management of bacterial meningitis.
Hart CA, Cuevas LE, Marzouk O, Thomson AP, Sills J
J Antimicrob Chemother 1993 Jul;32 Suppl A:49-59. doi: 10.1093/jac/32.suppl_a.49. PMID: 8407698
Bacterial meningitis in infants and children.
Marks MI
Infection 1984;12 Suppl 1:S52-7. doi: 10.1007/BF01641744. PMID: 6397450
Bacterial meningitis--1982.
Gold R
Am J Med 1983 Jul 28;75(1B):98-101. doi: 10.1016/0002-9343(83)90079-7. PMID: 6349348

Diagnosis

New diagnostic and therapeutic options in bacterial meningitis in infants and children.
Kim KS
Minerva Pediatr 2009 Oct;61(5):531-48. PMID: 19794379
Bacterial meningitis--an update.
Marks MI
Clin Pediatr (Phila) 1991 Dec;30(12):673-5. doi: 10.1177/000992289103001204. PMID: 1764875
Bacterial meningitis in infants and children.
Marks MI
Infection 1984;12 Suppl 1:S52-7. doi: 10.1007/BF01641744. PMID: 6397450
Bacterial meningitis--1982.
Gold R
Am J Med 1983 Jul 28;75(1B):98-101. doi: 10.1016/0002-9343(83)90079-7. PMID: 6349348
Diagnosis and management of bacterial meningitis.
Hambleton G, Davies PA
Drugs 1974;8(1):15-53. doi: 10.2165/00003495-197408010-00002. PMID: 4611738

Therapy

Adjunctive dexamethasone treatment in acute bacterial meningitis.
Chaudhuri A
Lancet Neurol 2004 Jan;3(1):54-62. doi: 10.1016/s1474-4422(03)00623-9. PMID: 14693112
Chemoprophylaxis of meningitis.
Jones DM
Trans R Soc Trop Med Hyg 1991;85 Suppl 1:44-5. doi: 10.1016/0035-9203(91)90340-5. PMID: 1803697
Steroids in meningitis.
Tarlow MJ, McCracken GH
Br J Hosp Med 1989 Nov;42(5):358. PMID: 2597823
Cephalosporin antibiotic agents.
Kemp R
Med J Aust 1984 Sep 29;141(7):437-42. doi: 10.5694/j.1326-5377.1984.tb132856.x. PMID: 6472182
Prophylaxis in haemophilus meningitis.
Lambert HP
Br Med J (Clin Res Ed) 1984 Mar 10;288(6419):739-40. doi: 10.1136/bmj.288.6419.739. PMID: 6423058Free PMC Article

Prognosis

Adjunctive dexamethasone treatment in acute bacterial meningitis.
Chaudhuri A
Lancet Neurol 2004 Jan;3(1):54-62. doi: 10.1016/s1474-4422(03)00623-9. PMID: 14693112
Management of bacterial meningitis.
Hart CA, Cuevas LE, Marzouk O, Thomson AP, Sills J
J Antimicrob Chemother 1993 Jul;32 Suppl A:49-59. doi: 10.1093/jac/32.suppl_a.49. PMID: 8407698
Treatment of bacterial meningitis.
Schaad UB
Eur J Clin Microbiol 1986 Oct;5(5):492-7. doi: 10.1007/BF02017689. PMID: 3536497
Bacterial meningitis in infants and children.
Marks MI
Infection 1984;12 Suppl 1:S52-7. doi: 10.1007/BF01641744. PMID: 6397450
Bacterial meningitis--1978.
Underman AE, Overturf GD, Leedom JM
Dis Mon 1978 Feb;24(5):1-63. doi: 10.1016/s0011-5029(78)80003-0. PMID: 376254

Clinical prediction guides

Community-acquired Haemophilus influenzae meningitis in adults.
Chekrouni N, Koelman DLH, Brouwer MC, van der Ende A, van de Beek D
J Infect 2021 May;82(5):145-150. Epub 2021 Mar 25 doi: 10.1016/j.jinf.2021.03.016. PMID: 33774020
Haemophilus influenzae type b disease in the era of conjugate vaccines: critical factors for successful eradication.
Slack M, Esposito S, Haas H, Mihalyi A, Nissen M, Mukherjee P, Harrington L
Expert Rev Vaccines 2020 Oct;19(10):903-917. Epub 2020 Oct 10 doi: 10.1080/14760584.2020.1825948. PMID: 32962476
Haemophilus influenzae type b vaccination and anthropometric, cognitive, and schooling outcomes among Indian children.
Nandi A, Deolalikar AB, Bloom DE, Laxminarayan R
Ann N Y Acad Sci 2019 Aug;1449(1):70-82. Epub 2019 Jun 10 doi: 10.1111/nyas.14127. PMID: 31180594Free PMC Article
The effect of Haemophilus influenzae type B and pneumococcal conjugate vaccines on childhood meningitis mortality: a systematic review.
Davis S, Feikin D, Johnson HL
BMC Public Health 2013;13 Suppl 3(Suppl 3):S21. Epub 2013 Sep 17 doi: 10.1186/1471-2458-13-S3-S21. PMID: 24564188Free PMC Article
Haemophilus influenzae type b meningitis: manifestations and long term sequelae.
Sell SH
Pediatr Infect Dis J 1987 Aug;6(8):775-8. doi: 10.1097/00006454-198708000-00035. PMID: 3313239

Recent systematic reviews

Efficacy and Prolonged Safety of Haemophilus influenzae Type b Conjugate Vaccines.
Tripathi N, Mukherjee S
Infect Disord Drug Targets 2024;24(5):e150124225640. doi: 10.2174/0118715265269877231117070051. PMID: 38231056
Estimating the global and regional burden of meningitis in children caused by Haemophilus influenzae type b: A systematic review and meta-analysis.
Park JJ, Narayanan S, Tiefenbach J, Lukšić I, Ale BM, Adeloye D, Rudan I
J Glob Health 2022;12:04014. Epub 2022 Mar 5 doi: 10.7189/jogh.12.04014. PMID: 35265327Free PMC Article
Incidence and aetiology of bacterial meningitis among children aged 1-59 months in South Asia: systematic review and meta-analysis.
Ali M, Chang BA, Johnson KW, Morris SK
Vaccine 2018 Sep 18;36(39):5846-5857. Epub 2018 Aug 23 doi: 10.1016/j.vaccine.2018.07.037. PMID: 30145101
The effect of Haemophilus influenzae type B and pneumococcal conjugate vaccines on childhood meningitis mortality: a systematic review.
Davis S, Feikin D, Johnson HL
BMC Public Health 2013;13 Suppl 3(Suppl 3):S21. Epub 2013 Sep 17 doi: 10.1186/1471-2458-13-S3-S21. PMID: 24564188Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...