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Hyperpigmentation, progressive cribriform and zosteriform(PCZH)

MedGen UID:
75526
Concept ID:
C0263579
Disease or Syndrome
Synonyms: HYPERPIGMENTATION, PROGRESSIVE CRIBRIFORM AND ZOSTERIFORM; PCZH
SNOMED CT: Pigmented hairy epidermal nevus (5387003); Becker's nevus (5387003); Pigmented hairy nevus of Becker (5387003); PCZH - progressive cribriform and zosteriform hyperpigmentation (878889000); Progressive cribriform and zosteriform hyperpigmentation (878889000)
 
Monarch Initiative: MONDO:0800357
OMIM®: 614323

Definition

A benign lesion that is sometimes congenital and consists of an overgrowth of the epidermis and the presence of melanin-containing cells. It is found mostly in males and typically develops during childhood or adolescence, becoming darker and more hairy after puberty. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperpigmentation, progressive cribriform and zosteriform

Recent clinical studies

Etiology

Das A, Mohanty S, Gharami RC, Chowdhury SN, Kumar P, Das NK, Bandyopadhyay D
Clin Exp Dermatol 2021 Dec;46(8):1452-1461. Epub 2021 Jul 6 doi: 10.1111/ced.14753. PMID: 34022084
Di Lernia V
Pediatr Dermatol 2007 May-Jun;24(3):205-10. doi: 10.1111/j.1525-1470.2007.00387.x. PMID: 17542865

Diagnosis

Das A, Mohanty S, Gharami RC, Chowdhury SN, Kumar P, Das NK, Bandyopadhyay D
Clin Exp Dermatol 2021 Dec;46(8):1452-1461. Epub 2021 Jul 6 doi: 10.1111/ced.14753. PMID: 34022084
Kim JY, Oh GN, Seo SH, Ahn HH, Kye YC, Choi JE
Cutis 2015 Jul;96(1):E4-6. PMID: 26244365
Cho E, Cho SH, Lee JD
Int J Dermatol 2012 Apr;51(4):399-405. doi: 10.1111/j.1365-4632.2011.04988.x. PMID: 22435426
Di Lernia V
Pediatr Dermatol 2007 May-Jun;24(3):205-10. doi: 10.1111/j.1525-1470.2007.00387.x. PMID: 17542865
Rower JM, Carr RD, Lowney ED
Arch Dermatol 1978 Jan;114(1):98-9. PMID: 619793

Clinical prediction guides

Cho E, Cho SH, Lee JD
Int J Dermatol 2012 Apr;51(4):399-405. doi: 10.1111/j.1365-4632.2011.04988.x. PMID: 22435426

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