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Craniolacunia

MedGen UID:
75575
•Concept ID:
C0265537
•
Congenital Abnormality
Synonym: Lacunar skull
SNOMED CT: Lückenschädel (29307005); Craniofenestria (29307005); Craniolacunia (29307005); Lacunar skull (29307005)

Definition

A congenital abnormality characterized by round or oval shaped defects in the membranous skull vault resulting in non-ossified, honey comb-like areas in the calvaria. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCraniolacunia

Professional guidelines

PubMed

Incomplete reossification after craniosynostosis surgery-incidence and analysis of risk factors: a clinical-radiological assessment study.
Thenier-Villa JL, Sanromán-Álvarez P, Miranda-Lloret P, Plaza Ramírez ME
J Neurosurg Pediatr 2018 Aug;22(2):120-127. Epub 2018 May 25 doi: 10.3171/2018.2.PEDS17717. PMID: 29799353

Recent clinical studies

Etiology

Craniolacunia and the Development of the Fetal Calvaria: An Autopsy Series With Clinical and Histological Analysis.
Reed RC
Pediatr Dev Pathol 2023 Mar-Apr;26(2):97-105. Epub 2022 Dec 27 doi: 10.1177/10935266221126477. PMID: 36573554
Incomplete reossification after craniosynostosis surgery-incidence and analysis of risk factors: a clinical-radiological assessment study.
Thenier-Villa JL, Sanromán-Álvarez P, Miranda-Lloret P, Plaza Ramírez ME
J Neurosurg Pediatr 2018 Aug;22(2):120-127. Epub 2018 May 25 doi: 10.3171/2018.2.PEDS17717. PMID: 29799353
Radiographic manifestations of congenital anomalies of the skull.
Kaplan SB, Kemp SS, Oh KS
Radiol Clin North Am 1991 Mar;29(2):195-218. PMID: 1998047
Klippel-Feil syndrome, iniencephalus, anencephalus, hindbrain hernia and mirror movements: overdistention of the neural tube.
Gardner WJ
Childs Brain 1979;5(4):361-79. doi: 10.1159/000119832. PMID: 456110

Diagnosis

Craniolacunia and the Development of the Fetal Calvaria: An Autopsy Series With Clinical and Histological Analysis.
Reed RC
Pediatr Dev Pathol 2023 Mar-Apr;26(2):97-105. Epub 2022 Dec 27 doi: 10.1177/10935266221126477. PMID: 36573554
Radiographic manifestations of congenital anomalies of the skull.
Kaplan SB, Kemp SS, Oh KS
Radiol Clin North Am 1991 Mar;29(2):195-218. PMID: 1998047
Craniolacunia diagnosed prenatally.
Liebeskind A, Jacobson R, Schechter MM
Neuroradiology 1971 Dec;3(2):109-12. doi: 10.1007/BF00339905. PMID: 4950598
CRANIOLACUNIA.
SHOPFNER CE, JABBOUR JT, VALLION RM
Am J Roentgenol Radium Ther Nucl Med 1965 Feb;93:343-9. PMID: 14258281
Craniolacunia diagnosed prenatally; review of literature with a case report.
D'AVERSA G, LONNGREN DH
Am J Roentgenol Radium Ther 1951 Apr;65(4):590-2. PMID: 14819439

Therapy

The efficacy of custom-made porous hydroxyapatite prostheses for cranioplasty: evaluation of postmarketing data on 2697 patients.
Stefini R, Zanotti B, Nataloni A, Martinetti R, Scafuto M, Colasurdo M, Tampieri A
J Appl Biomater Funct Mater 2015 Jul 4;13(2):e136-44. doi: 10.5301/jabfm.5000211. PMID: 25589160

Prognosis

Incomplete reossification after craniosynostosis surgery-incidence and analysis of risk factors: a clinical-radiological assessment study.
Thenier-Villa JL, Sanromán-Álvarez P, Miranda-Lloret P, Plaza Ramírez ME
J Neurosurg Pediatr 2018 Aug;22(2):120-127. Epub 2018 May 25 doi: 10.3171/2018.2.PEDS17717. PMID: 29799353
Radiographic manifestations of congenital anomalies of the skull.
Kaplan SB, Kemp SS, Oh KS
Radiol Clin North Am 1991 Mar;29(2):195-218. PMID: 1998047
Klippel-Feil syndrome, iniencephalus, anencephalus, hindbrain hernia and mirror movements: overdistention of the neural tube.
Gardner WJ
Childs Brain 1979;5(4):361-79. doi: 10.1159/000119832. PMID: 456110

Clinical prediction guides

Incomplete reossification after craniosynostosis surgery-incidence and analysis of risk factors: a clinical-radiological assessment study.
Thenier-Villa JL, Sanromán-Álvarez P, Miranda-Lloret P, Plaza Ramírez ME
J Neurosurg Pediatr 2018 Aug;22(2):120-127. Epub 2018 May 25 doi: 10.3171/2018.2.PEDS17717. PMID: 29799353
Duplication 5q and deletion 9p due to a t(5;9)(q34;p23) in 2 cousins with features of Hunter-McAlpine syndrome and hypothyroidism.
Vásquez-Velásquez AI, García-Castillo HA, González-Mercado MG, Dávalos IP, Raca G, Xu X, Dwyer E, Rivera H
Cytogenet Genome Res 2011;132(4):233-8. Epub 2010 Nov 10 doi: 10.1159/000321647. PMID: 21063078
Radiographic manifestations of congenital anomalies of the skull.
Kaplan SB, Kemp SS, Oh KS
Radiol Clin North Am 1991 Mar;29(2):195-218. PMID: 1998047
Craniolacunia in newborn with myelomeningocele.
Tajima M, Yamada H, Kageyama N
Childs Brain 1977;3(5):297-303. doi: 10.1159/000119679. PMID: 902512
Observations on craniolacunia.
McRae DL
Acta Radiol Diagn (Stockh) 1966;5:55-64. doi: 10.1177/02841851660050p105. PMID: 5334510

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