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Congenital hydronephrosis

MedGen UID:
78594
•Concept ID:
C0266316
•
Congenital Abnormality
Synonyms: Congenital Hydronephrosis; congenital hydronephrosis; Primary hydronephrosis
SNOMED CT: Primary hydronephrosis (16297002); Congenital hydronephrosis (16297002)
 
Monarch Initiative: MONDO:0007741

Definition

Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces that is present at birth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCongenital hydronephrosis
Follow this link to review classifications for Congenital hydronephrosis in Orphanet.

Professional guidelines

PubMed

Pediatric congenital hydronephrosis (ureteropelvic junction obstruction): Medical management guide.
Kohno M, Ogawa T, Kojima Y, Sakoda A, Johnin K, Sugita Y, Nakane A, Noguchi M, Moriya K, Hattori M, Hayashi Y, Kubota M
Int J Urol 2020 May;27(5):369-376. Epub 2020 Mar 11 doi: 10.1111/iju.14207. PMID: 32162424
Prenatal diagnosis and management of hydronephrosis.
Pates JA, Dashe JS
Early Hum Dev 2006 Jan;82(1):3-8. Epub 2005 Dec 27 doi: 10.1016/j.earlhumdev.2005.11.003. PMID: 16380224
Congenital unilateral hydronephrosis: a review of the impact of diuretic renography on clinical treatment.
Eskild-Jensen A, Gordon I, Piepsz A, Frøkiaer J
J Urol 2005 May;173(5):1471-6. doi: 10.1097/01.ju.0000157384.32215.fe. PMID: 15821462

Recent clinical studies

Etiology

Do current scientific reports of hydronephrosis make the grade?
Suson KD, Preece J
J Pediatr Urol 2020 Oct;16(5):597.e1-597.e6. Epub 2020 Apr 10 doi: 10.1016/j.jpurol.2020.04.003. PMID: 32345558
ATP5B and ETFB metabolic markers in children with congenital hydronephrosis.
Zhao Q, Yang Y, Wang C, Hou Y, Chen H
Mol Med Rep 2016 Dec;14(6):5111-5115. Epub 2016 Nov 1 doi: 10.3892/mmr.2016.5914. PMID: 27840937Free PMC Article
Prenatal hydronephrosis: postnatal evaluation and management.
Vemulakonda V, Yiee J, Wilcox DT
Curr Urol Rep 2014 Aug;15(8):430. doi: 10.1007/s11934-014-0430-5. PMID: 24927968
Incidence and outcomes of antenatally detected congenital hydronephrosis.
Kari JA, Habiballah S, Alsaedi SA, Alsaggaf H, Al-dabbagh A, AbulHamail A, Marzouki A, Eldeek B
Ann Saudi Med 2013 May-Jun;33(3):260-4. doi: 10.5144/0256-4947.2013.260. PMID: 23793428Free PMC Article
Congenital unilateral hydronephrosis: a review of the impact of diuretic renography on clinical treatment.
Eskild-Jensen A, Gordon I, Piepsz A, Frøkiaer J
J Urol 2005 May;173(5):1471-6. doi: 10.1097/01.ju.0000157384.32215.fe. PMID: 15821462

Diagnosis

Ureteropelvic Junction Obstruction/Hydronephrosis.
Cai PY, Lee RS
Urol Clin North Am 2023 Aug;50(3):361-369. Epub 2023 May 22 doi: 10.1016/j.ucl.2023.04.001. PMID: 37385700
Do current scientific reports of hydronephrosis make the grade?
Suson KD, Preece J
J Pediatr Urol 2020 Oct;16(5):597.e1-597.e6. Epub 2020 Apr 10 doi: 10.1016/j.jpurol.2020.04.003. PMID: 32345558
Prenatal hydronephrosis: postnatal evaluation and management.
Vemulakonda V, Yiee J, Wilcox DT
Curr Urol Rep 2014 Aug;15(8):430. doi: 10.1007/s11934-014-0430-5. PMID: 24927968
Congenital hydronephrosis.
Frazier JP, Parks DK, Yetman RJ
J Pediatr Health Care 2001 Sep-Oct;15(5):260-2. doi: 10.1067/mph.2001.117380. PMID: 11562646
Prenatal diagnosis and management of bilateral hydronephrosis.
Crombleholme TM, Harrison MR, Longaker MT, Langer JC
Pediatr Nephrol 1988 Jul;2(3):334-42. doi: 10.1007/BF00858690. PMID: 3153038

Therapy

Associations between PM(2.5), ambient heat exposure and congenital hydronephrosis in southeastern China.
Huang Z, Zhong X, Shen T, Gu S, Chen M, Xu W, Chen R, Wu J, Yang X
Front Public Health 2024;12:1389969. Epub 2024 Jul 29 doi: 10.3389/fpubh.2024.1389969. PMID: 39135922Free PMC Article
Pre-pregnancy obesity and risk of congenital abnormalities of the kidney and urinary tract (CAKUT)-systematic review, meta-analysis and ecological study.
Jadresić L, Au H, Woodhouse C, Nitsch D
Pediatr Nephrol 2021 Jan;36(1):119-132. Epub 2020 Jun 28 doi: 10.1007/s00467-020-04679-0. PMID: 32596798
Trends in congenital anomalies in Europe from 1980 to 2012.
Morris JK, Springett AL, Greenlees R, Loane M, Addor MC, Arriola L, Barisic I, Bergman JEH, Csaky-Szunyogh M, Dias C, Draper ES, Garne E, Gatt M, Khoshnood B, Klungsoyr K, Lynch C, McDonnell R, Nelen V, Neville AJ, O'Mahony M, Pierini A, Queisser-Luft A, Randrianaivo H, Rankin J, Rissmann A, Kurinczuk J, Tucker D, Verellen-Dumoulin C, Wellesley D, Dolk H
PLoS One 2018;13(4):e0194986. Epub 2018 Apr 5 doi: 10.1371/journal.pone.0194986. PMID: 29621304Free PMC Article
Upper urinary tract: when is obstruction obstruction?
Csaicsich D, Greenbaum LA, Aufricht C
Curr Opin Urol 2004 Jul;14(4):213-7. doi: 10.1097/01.mou.0000135075.19968.d9. PMID: 15205576
Supranormal renographic differential renal function in congenital hydronephrosis: fact, not artifact.
Capolicchio G, Jednak R, Dinh L, Salle JL, Brzezinski A, Houle AM
J Urol 1999 Apr;161(4):1290-4. PMID: 10081895

Prognosis

Ureteropelvic Junction Obstruction/Hydronephrosis.
Cai PY, Lee RS
Urol Clin North Am 2023 Aug;50(3):361-369. Epub 2023 May 22 doi: 10.1016/j.ucl.2023.04.001. PMID: 37385700
Pediatric congenital hydronephrosis (ureteropelvic junction obstruction): Medical management guide.
Kohno M, Ogawa T, Kojima Y, Sakoda A, Johnin K, Sugita Y, Nakane A, Noguchi M, Moriya K, Hattori M, Hayashi Y, Kubota M
Int J Urol 2020 May;27(5):369-376. Epub 2020 Mar 11 doi: 10.1111/iju.14207. PMID: 32162424
The Role of microRNAs Identified in the Amniotic Fluid.
Fasoulakis Z, Theodora M, Tsirkas I, Tsirka T, Kalagasidou S, Inagamova L, Papamanolis V, Blontzos N, Kontomanolis EN
Microrna 2020;9(1):8-16. doi: 10.2174/2211536608666190318105140. PMID: 30887932
Incidence and outcomes of antenatally detected congenital hydronephrosis.
Kari JA, Habiballah S, Alsaedi SA, Alsaggaf H, Al-dabbagh A, AbulHamail A, Marzouki A, Eldeek B
Ann Saudi Med 2013 May-Jun;33(3):260-4. doi: 10.5144/0256-4947.2013.260. PMID: 23793428Free PMC Article
Prenatal diagnosis and management of bilateral hydronephrosis.
Crombleholme TM, Harrison MR, Longaker MT, Langer JC
Pediatr Nephrol 1988 Jul;2(3):334-42. doi: 10.1007/BF00858690. PMID: 3153038

Clinical prediction guides

Ureteropelvic Junction Obstruction/Hydronephrosis.
Cai PY, Lee RS
Urol Clin North Am 2023 Aug;50(3):361-369. Epub 2023 May 22 doi: 10.1016/j.ucl.2023.04.001. PMID: 37385700
The Role of microRNAs Identified in the Amniotic Fluid.
Fasoulakis Z, Theodora M, Tsirkas I, Tsirka T, Kalagasidou S, Inagamova L, Papamanolis V, Blontzos N, Kontomanolis EN
Microrna 2020;9(1):8-16. doi: 10.2174/2211536608666190318105140. PMID: 30887932
Colour Doppler and Biomarkers Utility for Renal Damage due to Congenital Hydronephrosis.
Guo YN, Chen XY, Liu LL
J Coll Physicians Surg Pak 2019 Feb;29(2):141-144. doi: 10.29271/jcpsp.2019.02.141. PMID: 30700353
Expression and clinical significance of aquaporin-1 and ET-1 in urine of children with congenital hydronephrosis.
Yu Y, Kang YF, Li KS, Chen ZH, Zhang L, Zhang HM, Zhang M
Eur Rev Med Pharmacol Sci 2017 Sep;21(18):4141-4146. PMID: 29028084
Incidence and outcomes of antenatally detected congenital hydronephrosis.
Kari JA, Habiballah S, Alsaedi SA, Alsaggaf H, Al-dabbagh A, AbulHamail A, Marzouki A, Eldeek B
Ann Saudi Med 2013 May-Jun;33(3):260-4. doi: 10.5144/0256-4947.2013.260. PMID: 23793428Free PMC Article

Recent systematic reviews

Comparison between open and minimally invasive pyeloplasty in infants: A systematic review and meta-analysis.
Ortiz-Seller D, Panach-Navarrete J, Valls-González L, Martínez-Jabaloyas JM
J Pediatr Urol 2024 Apr;20(2):244-252. Epub 2023 Nov 23 doi: 10.1016/j.jpurol.2023.11.017. PMID: 38065760
Pre-pregnancy obesity and risk of congenital abnormalities of the kidney and urinary tract (CAKUT)-systematic review, meta-analysis and ecological study.
Jadresić L, Au H, Woodhouse C, Nitsch D
Pediatr Nephrol 2021 Jan;36(1):119-132. Epub 2020 Jun 28 doi: 10.1007/s00467-020-04679-0. PMID: 32596798

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