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Localized Parathyroid Gland Carcinoma

MedGen UID:
82959
•Concept ID:
C0278680
•
Neoplastic Process
Synonyms: Localized Parathyroid Cancer; Localized Parathyroid Carcinoma

Definition

A parathyroid gland carcinoma that has not spread to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Parathyroid Gland Carcinoma

Professional guidelines

PubMed

Diagnosis and Management of Parathyroid Carcinoma.
Lazzaro A, Zhao GQ, Kulke M
Clin Pharmacol Ther 2024 Dec;116(6):1496-1505. Epub 2024 Sep 5 doi: 10.1002/cpt.3432. PMID: 39234888
Editorial: Parathyroid atypical adenomas and carcinoma: An update on clinical management.
Gianotti L, Cetani F
Front Endocrinol (Lausanne) 2023;14:1163996. Epub 2023 Feb 24 doi: 10.3389/fendo.2023.1163996. PMID: 36909324Free PMC Article
Management of thyroid cancer: United Kingdom National Multidisciplinary Guidelines.
Mitchell AL, Gandhi A, Scott-Coombes D, Perros P
J Laryngol Otol 2016 May;130(S2):S150-S160. doi: 10.1017/S0022215116000578. PMID: 27841128Free PMC Article

Recent clinical studies

Etiology

Parathyroid carcinoma and atypical parathyroid tumor: analysis of an Italian database.
Marini F, Marcucci G, Giusti F, Arvat E, Benvenga S, Bondanelli M, Castellino L, Camozzi V, Corbetta S, Davì MV, Famà F, Ferone D, Iacobone M, Loli P, Mantovani G, Pagotto U, Persani L, Perigli G, Piovesan A, Repaci A, Ruggeri RM, Eller-Vainicher C, Vera L, Zatelli MC, Zavatta G, Brandi ML
Eur J Endocrinol 2024 Sep 30;191(4):416-425. doi: 10.1093/ejendo/lvae121. PMID: 39365596
Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Dwarfs and Giants of Parathyroid Adenomas-No Difference in Outcome After Parathyroidectomy.
Abdel-Aziz TE, Gleeson F, Sadler G, Mihai R
J Surg Res 2019 May;237:56-60. Epub 2019 Jan 25 doi: 10.1016/j.jss.2018.12.021. PMID: 30694792
Parathyroid carcinoma.
Thompson LD
Ear Nose Throat J 2009 Jan;88(1):722-4. PMID: 19172564
Parathyroid carcinoma.
Thompson LD
Ear Nose Throat J 2008 Sep;87(9):502-4. PMID: 18800320

Diagnosis

Parathyroid Imaging.
Lalonde MN, Correia RD, Syktiotis GP, Schaefer N, Matter M, Prior JO
Semin Nucl Med 2023 Jul;53(4):490-502. Epub 2023 Mar 14 doi: 10.1053/j.semnuclmed.2023.02.004. PMID: 36922339
Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Parathyroid Carcinoma.
Cetani F, Pardi E, Marcocci C
Front Horm Res 2019;51:63-76. Epub 2018 Nov 19 doi: 10.1159/000491039. PMID: 30641523
Imaging of the parathyroid glands.
Phillips CD, Shatzkes DR
Semin Ultrasound CT MR 2012 Apr;33(2):123-9. doi: 10.1053/j.sult.2011.12.003. PMID: 22410360
Parathyroid carcinoma.
Thompson LD
Ear Nose Throat J 2009 Jan;88(1):722-4. PMID: 19172564

Therapy

Refractory paraneoplastic hypercalcaemia responding to cinacalcet.
Shah PM, Rasool I, Maguire D
BMJ Case Rep 2022 Nov 15;15(11) doi: 10.1136/bcr-2022-250576. PMID: 36379628Free PMC Article
A garden of parathyroid adenomas.
Sahli ZT, Karipineni F, Zeiger MA
BMJ Case Rep 2017 Aug 3;2017 doi: 10.1136/bcr-2017-221130. PMID: 28775107Free PMC Article
Parathyroid carcinoma.
Thompson LD
Ear Nose Throat J 2008 Sep;87(9):502-4. PMID: 18800320
Current issues in hyperparathyroidism.
Krempl GA, Medina JE
Otolaryngol Clin North Am 2003 Feb;36(1):207-15. doi: 10.1016/s0030-6665(02)00154-8. PMID: 12803017
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115

Prognosis

Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Parathyroid carcinoma.
Thompson LD
Ear Nose Throat J 2009 Jan;88(1):722-4. PMID: 19172564
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115
Hyperfunctioning parathyroid carcinoma.
Abrahams TG, Hanks P, Jones M
Skeletal Radiol 2000 Feb;29(2):112-5. doi: 10.1007/s002560050022. PMID: 10741503
Parathyroid carcinoma: a collective review.
Holmes EC, Morton DL, Ketcham AS
Ann Surg 1969 Apr;169(4):631-40. doi: 10.1097/00000658-196904000-00022. PMID: 4886854Free PMC Article

Clinical prediction guides

Perioperative Clinical Features of Mediastinal Parathyroid Adenoma: A Case Series.
Wang F, Zhang H, Qiu G, Wang Y
Thorac Cardiovasc Surg 2022 Oct;70(7):596-600. Epub 2022 Jul 28 doi: 10.1055/s-0042-1750026. PMID: 35901849
Parathyroid surgery: from inception to the modern day.
Sethi N, England RJA
Br J Hosp Med (Lond) 2017 Jun 2;78(6):333-337. doi: 10.12968/hmed.2017.78.6.333. PMID: 28614027
Parathyroid 4D-CT: Multi-institutional International Survey of Use and Trends.
Hoang JK, Williams K, Gaillard F, Dixon A, Sosa JA
Otolaryngol Head Neck Surg 2016 Dec;155(6):956-960. Epub 2016 Jun 21 doi: 10.1177/0194599816655311. PMID: 27329424
Update on parathyroid carcinoma.
Cetani F, Pardi E, Marcocci C
J Endocrinol Invest 2016 Jun;39(6):595-606. Epub 2016 Mar 21 doi: 10.1007/s40618-016-0447-3. PMID: 27001435
The elusive parathyroid adenoma: techniques for detection.
Devcic Z, Jeffrey RB, Kamaya A, Desser TS
Ultrasound Q 2013 Sep;29(3):179-87. doi: 10.1097/RUQ.0b013e3182a1ba6f. PMID: 23975046

Recent systematic reviews

Total thyroidectomy versus unilateral lobectomy for unilateral multifocal papillary thyroid carcinoma: systematic review and meta‑analysis.
Chen H, Liu Y, Huang D, Zhang X, She L
Updates Surg 2024 Jan;76(1):33-41. Epub 2023 Dec 21 doi: 10.1007/s13304-023-01726-x. PMID: 38127193
Parathyroid Cystic Adenoma: A Systematic Review and Meta-Analysis.
Daoud A, Ronen O
Endocr Pract 2023 Jan;29(1):2-10. Epub 2022 Nov 10 doi: 10.1016/j.eprac.2022.11.004. PMID: 36370985
Hürthle Cell Carcinoma of the Thyroid Gland: Systematic Review and Meta-analysis.
Coca-Pelaz A, Rodrigo JP, Shah JP, Sanabria A, Al Ghuzlan A, Silver CE, Shaha AR, Angelos P, Hartl DM, Mäkitie AA, Olsen KD, Owen RP, Randolph GW, Simó R, Tufano RP, Kowalski LP, Zafereo ME, Rinaldo A, Ferlito A
Adv Ther 2021 Oct;38(10):5144-5164. Epub 2021 Aug 22 doi: 10.1007/s12325-021-01876-7. PMID: 34423400
Parathyroid cancer: A systematic review of diagnostic biomarkers.
Davies MP, John Evans TW, Tahir F, Balasubramanian SP
Surgeon 2021 Dec;19(6):e536-e548. Epub 2021 Feb 26 doi: 10.1016/j.surge.2021.01.011. PMID: 33642204
Decision making for the central compartment in differentiated thyroid cancer.
Gonçalves Filho J, Zafereo ME, Ahmad FI, Nixon IJ, Shaha AR, Vander Poorten V, Sanabria A, Hefetz AK, Robbins KT, Kamani D, Randolph GW, Coca-Pelaz A, Simo R, Rinaldo A, Angelos P, Ferlito A, Kowalski LP
Eur J Surg Oncol 2018 Nov;44(11):1671-1678. Epub 2018 Aug 13 doi: 10.1016/j.ejso.2018.08.005. PMID: 30145001

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