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Pulmonary chondroma

MedGen UID:
833710
•Concept ID:
C3203483
•
Neoplastic Process
Synonyms: Lung Chondroma; Pulmonary Chondroma
 
HPO: HP:0031474

Definition

A benign cartilaginous tumors of the lung. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary chondroma

Professional guidelines

PubMed

Strategies of treatment of chest wall tumors and our experience.
Chudacek J, Bohanes T, Szkorupa M, Klein J, Stasek M, Zalesak B, Stehlik D, Ctvrtlík F, Neoral C
Rozhl Chir 2015 Jan;94(1):17-23. PMID: 25604980
Chondroma of the bronchus in childhood: a case report illustrating problems in diagnosis and management.
Shermeta DW, Carter D, Haller JA Jr
J Pediatr Surg 1975 Aug;10(4):545-8. doi: 10.1016/0022-3468(75)90203-1. PMID: 1151593

Recent clinical studies

Etiology

Computed Tomography Imaging Findings of Pulmonary Chondroma.
Wang H, Nie P, Dong C, Hou F, Zhang P, Lin J, Liu J
Biomed Res Int 2018;2018:4387689. Epub 2018 Dec 30 doi: 10.1155/2018/4387689. PMID: 30687744Free PMC Article
Carney triad: a syndrome featuring paraganglionic, adrenocortical, and possibly other endocrine tumors.
Carney JA
J Clin Endocrinol Metab 2009 Oct;94(10):3656-62. Epub 2009 Sep 1 doi: 10.1210/jc.2009-1156. PMID: 19723753
Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma.
Rodriguez FJ, Aubry MC, Tazelaar HD, Slezak J, Carney JA
Am J Surg Pathol 2007 Dec;31(12):1844-53. doi: 10.1097/PAS.0b013e3180caa0b5. PMID: 18043038
Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence.
Carney JA
Mayo Clin Proc 1999 Jun;74(6):543-52. doi: 10.4065/74.6.543. PMID: 10377927
Extra-adrenal paraganglioma and pulmonary chondroma: a case report and review of the literature.
Keyhani-Rofagha S, O'Dorisio TM, Lucas JG, Fontana MB, Tuttle SE
J Surg Oncol 1987 Jun;35(2):89-95. doi: 10.1002/jso.2930350205. PMID: 2884350

Diagnosis

Carney's triad in an adult male from a tertiary care center in India: a case report.
Tansir G, Dash NR, Galodha S, Das P, Shamim SA, Rastogi S
J Med Case Rep 2021 Nov 16;15(1):559. doi: 10.1186/s13256-021-03149-x. PMID: 34782012Free PMC Article
Computed Tomography Imaging Findings of Pulmonary Chondroma.
Wang H, Nie P, Dong C, Hou F, Zhang P, Lin J, Liu J
Biomed Res Int 2018;2018:4387689. Epub 2018 Dec 30 doi: 10.1155/2018/4387689. PMID: 30687744Free PMC Article
Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma.
Rodriguez FJ, Aubry MC, Tazelaar HD, Slezak J, Carney JA
Am J Surg Pathol 2007 Dec;31(12):1844-53. doi: 10.1097/PAS.0b013e3180caa0b5. PMID: 18043038
Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence.
Carney JA
Mayo Clin Proc 1999 Jun;74(6):543-52. doi: 10.4065/74.6.543. PMID: 10377927
Carney syndrome: radiologic features.
Schmutz GR, Fisch-Ponsot C, Sylvestre J
Can Assoc Radiol J 1994 Apr;45(2):148-50. PMID: 8149274

Therapy

Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors.
Celestino R, Lima J, Faustino A, Vinagre J, Máximo V, Gouveia A, Soares P, Lopes JM
Eur J Hum Genet 2013 May;21(5):503-10. Epub 2012 Sep 5 doi: 10.1038/ejhg.2012.205. PMID: 22948025Free PMC Article
Incomplete Carney triad--a review of two cases.
Sawhney SA, Chapman AD, Carney JA, Gomersall LN, Dempsey OJ
QJM 2009 Sep;102(9):649-53. Epub 2009 Jun 26 doi: 10.1093/qjmed/hcp078. PMID: 19561114
Carney's triad: a 16-year follow-up.
Raffensperger J, Krueger R
J Pediatr Surg 2007 Aug;42(8):1452-3. doi: 10.1016/j.jpedsurg.2007.03.058. PMID: 17706515
Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization.
Agaimy A, Pelz AF, Corless CL, Wünsch PH, Heinrich MC, Hofstaedter F, Dietmaier W, Blanke CD, Wieacker P, Roessner A, Hartmann A, Schneider-Stock R
Oncol Rep 2007 Jul;18(1):9-15. PMID: 17549339
Gastric tumors in patients with pulmonary chondroma or extra-adrenal paraganglioma: an ultrastructural study.
Wick MR, Ruebner BH, Carney JA
Arch Pathol Lab Med 1981 Oct;105(10):527-31. PMID: 6895164

Prognosis

Succinate dehydrogenase (SDH)-deficient neoplasia.
Gill AJ
Histopathology 2018 Jan;72(1):106-116. doi: 10.1111/his.13277. PMID: 29239034
Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome.
Carney JA, Stratakis CA, Young WF Jr
Am J Surg Pathol 2013 Aug;37(8):1140-9. doi: 10.1097/PAS.0b013e318285f6a2. PMID: 23681078Free PMC Article
Carney triad: a syndrome featuring paraganglionic, adrenocortical, and possibly other endocrine tumors.
Carney JA
J Clin Endocrinol Metab 2009 Oct;94(10):3656-62. Epub 2009 Sep 1 doi: 10.1210/jc.2009-1156. PMID: 19723753
Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence.
Carney JA
Mayo Clin Proc 1999 Jun;74(6):543-52. doi: 10.4065/74.6.543. PMID: 10377927
The triad of gastric epithelioid leiomyosarcoma, pulmonary chondroma, and functioning extra-adrenal paraganglioma: a five-year review.
Carney JA
Medicine (Baltimore) 1983 May;62(3):159-69. doi: 10.1097/00005792-198305000-00003. PMID: 6843355

Clinical prediction guides

SDHC Methylation Pattern in Patients With Carney Triad.
Daumova M, Svajdler M, Fabian P, Kren L, Babankova I, Jezova M, Sedivcova M, Vanecek T, Behenska K, Michal M, Daum O
Appl Immunohistochem Mol Morphol 2021 Sep 1;29(8):599-605. doi: 10.1097/PAI.0000000000000920. PMID: 33624983
Succinate dehydrogenase (SDH)-deficient neoplasia.
Gill AJ
Histopathology 2018 Jan;72(1):106-116. doi: 10.1111/his.13277. PMID: 29239034
68Ga-DOTA-TATE PET/CT for Molecular Imaging of Somatostatin Receptor Expression in Extra-adrenal Paraganglioma in a Case of Complete Carney Triad.
Derlin T, Hartung D, Hueper K
Clin Nucl Med 2017 Dec;42(12):e527-e528. doi: 10.1097/RLU.0000000000001864. PMID: 29076898
Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome.
Carney JA, Stratakis CA, Young WF Jr
Am J Surg Pathol 2013 Aug;37(8):1140-9. doi: 10.1097/PAS.0b013e318285f6a2. PMID: 23681078Free PMC Article
Carney's triad: a 16-year follow-up.
Raffensperger J, Krueger R
J Pediatr Surg 2007 Aug;42(8):1452-3. doi: 10.1016/j.jpedsurg.2007.03.058. PMID: 17706515

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