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Metastatic Malignant Neoplasm in the Pituitary Gland

MedGen UID:
83847
Concept ID:
C0347015
Neoplastic Process
Synonyms: Cancer metastatic to pituitary gland; Metastasis to pituitary; Metastasis to Pituitary Gland; Metastatic malignant neoplasm of pituitary gland; Metastatic malignant neoplasm to pituitary gland; Metastatic Malignant Neoplasm to the Pituitary Gland; Metastatic Neoplasm to the Pituitary Gland; Secondary malignant neoplasm of pituitary gland
SNOMED CT: Metastasis to pituitary (94491007); Secondary malignant neoplasm of pituitary gland (94491007); Metastatic malignant neoplasm to pituitary gland (94491007); Cancer metastatic to pituitary gland (94491007); Metastatic malignant neoplasm of pituitary gland (94491007)

Definition

A malignant neoplasm metastasizing to the pituitary gland from another anatomic site. The vast majority are carcinomas usually arising from the breast, lung, and gastrointestinal tract. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Pituitary Gland

Professional guidelines

PubMed

Hong CS, Omay SB
Curr Oncol 2022 Feb 24;29(3):1408-1421. doi: 10.3390/curroncol29030118. PMID: 35323318Free PMC Article
Nagarajan N, Jalal D
Adv Chronic Kidney Dis 2019 Mar;26(2):99-109. doi: 10.1053/j.ackd.2019.03.002. PMID: 31023454
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Recent clinical studies

Etiology

Villa C, Baussart B, Assié G, Raverot G, Roncaroli F
Endocr Relat Cancer 2023 Aug 1;30(8) Epub 2023 Jun 22 doi: 10.1530/ERC-23-0021. PMID: 37068095
Deutschbein T, Reimondo G, Di Dalmazi G, Bancos I, Patrova J, Vassiliadi DA, Nekić AB, Debono M, Lardo P, Ceccato F, Petramala L, Prete A, Chiodini I, Ivović M, Pazaitou-Panayiotou K, Alexandraki KI, Hanzu FA, Loli P, Yener S, Langton K, Spyroglou A, Kocjan T, Zacharieva S, Valdés N, Ambroziak U, Suzuki M, Detomas M, Puglisi S, Tucci L, Delivanis DA, Margaritopoulos D, Dusek T, Maggio R, Scaroni C, Concistrè A, Ronchi CL, Altieri B, Mosconi C, Diamantopoulos A, Iñiguez-Ariza NM, Vicennati V, Pia A, Kroiss M, Kaltsas G, Chrisoulidou A, Marina LV, Morelli V, Arlt W, Letizia C, Boscaro M, Stigliano A, Kastelan D, Tsagarakis S, Athimulam S, Pagotto U, Maeder U, Falhammar H, Newell-Price J, Terzolo M, Fassnacht M
Lancet Diabetes Endocrinol 2022 Jul;10(7):499-508. Epub 2022 May 6 doi: 10.1016/S2213-8587(22)00100-0. PMID: 35533704Free PMC Article
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Briet C, Salenave S, Bonneville JF, Laws ER, Chanson P
Endocr Rev 2015 Dec;36(6):622-45. Epub 2015 Sep 28 doi: 10.1210/er.2015-1042. PMID: 26414232
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Diagnosis

Villa C, Baussart B, Assié G, Raverot G, Roncaroli F
Endocr Relat Cancer 2023 Aug 1;30(8) Epub 2023 Jun 22 doi: 10.1530/ERC-23-0021. PMID: 37068095
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Hamblin R, Tsermoulas G, Karavitaki N
Presse Med 2021 Dec;50(4):104078. Epub 2021 Oct 22 doi: 10.1016/j.lpm.2021.104078. PMID: 34688870
Chiloiro S, Giampietro A, Bianchi A, De Marinis L
Handb Clin Neurol 2021;181:29-40. doi: 10.1016/B978-0-12-820683-6.00003-8. PMID: 34238465
Briet C, Salenave S, Bonneville JF, Laws ER, Chanson P
Endocr Rev 2015 Dec;36(6):622-45. Epub 2015 Sep 28 doi: 10.1210/er.2015-1042. PMID: 26414232

Therapy

Baudin E, Goichot B, Berruti A, Hadoux J, Moalla S, Laboureau S, Nölting S, de la Fouchardière C, Kienitz T, Deutschbein T, Zovato S, Amar L, Haissaguerre M, Timmers H, Niccoli P, Faggiano A, Angokai M, Lamartina L, Luca F, Cosentini D, Hahner S, Beuschlein F, Attard M, Texier M, Fassnacht M; ENDOCAN-COMETE; ENSAT Networks
Lancet 2024 Mar 16;403(10431):1061-1070. Epub 2024 Feb 22 doi: 10.1016/S0140-6736(23)02554-0. PMID: 38402886
Deutschbein T, Reimondo G, Di Dalmazi G, Bancos I, Patrova J, Vassiliadi DA, Nekić AB, Debono M, Lardo P, Ceccato F, Petramala L, Prete A, Chiodini I, Ivović M, Pazaitou-Panayiotou K, Alexandraki KI, Hanzu FA, Loli P, Yener S, Langton K, Spyroglou A, Kocjan T, Zacharieva S, Valdés N, Ambroziak U, Suzuki M, Detomas M, Puglisi S, Tucci L, Delivanis DA, Margaritopoulos D, Dusek T, Maggio R, Scaroni C, Concistrè A, Ronchi CL, Altieri B, Mosconi C, Diamantopoulos A, Iñiguez-Ariza NM, Vicennati V, Pia A, Kroiss M, Kaltsas G, Chrisoulidou A, Marina LV, Morelli V, Arlt W, Letizia C, Boscaro M, Stigliano A, Kastelan D, Tsagarakis S, Athimulam S, Pagotto U, Maeder U, Falhammar H, Newell-Price J, Terzolo M, Fassnacht M
Lancet Diabetes Endocrinol 2022 Jul;10(7):499-508. Epub 2022 May 6 doi: 10.1016/S2213-8587(22)00100-0. PMID: 35533704Free PMC Article
Briet C, Salenave S, Bonneville JF, Laws ER, Chanson P
Endocr Rev 2015 Dec;36(6):622-45. Epub 2015 Sep 28 doi: 10.1210/er.2015-1042. PMID: 26414232
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989
Lin HW, Shih SR, Yao M, Huang TS
Endocr Pathol 2012 Sep;23(3):172-6. doi: 10.1007/s12022-012-9203-1. PMID: 22527946

Prognosis

Villa C, Baussart B, Assié G, Raverot G, Roncaroli F
Endocr Relat Cancer 2023 Aug 1;30(8) Epub 2023 Jun 22 doi: 10.1530/ERC-23-0021. PMID: 37068095
Henry A, Nugent A, Wallace IR, Oladipo B, Sheehy O, Johnston PC
Ulster Med J 2021 Sep;90(3):146-150. Epub 2021 Nov 11 PMID: 34815592Free PMC Article
Hamblin R, Tsermoulas G, Karavitaki N
Presse Med 2021 Dec;50(4):104078. Epub 2021 Oct 22 doi: 10.1016/j.lpm.2021.104078. PMID: 34688870
Feng Y, Mao ZG, Wang X, Du Q, Jian M, Zhu D, Xiao Z, Wang HJ, Zhu YH
Horm Metab Res 2018 Mar;50(3):179-192. Epub 2018 Jan 19 doi: 10.1055/s-0043-123763. PMID: 29351706
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477

Clinical prediction guides

Villa C, Baussart B, Assié G, Raverot G, Roncaroli F
Endocr Relat Cancer 2023 Aug 1;30(8) Epub 2023 Jun 22 doi: 10.1530/ERC-23-0021. PMID: 37068095
Deutschbein T, Reimondo G, Di Dalmazi G, Bancos I, Patrova J, Vassiliadi DA, Nekić AB, Debono M, Lardo P, Ceccato F, Petramala L, Prete A, Chiodini I, Ivović M, Pazaitou-Panayiotou K, Alexandraki KI, Hanzu FA, Loli P, Yener S, Langton K, Spyroglou A, Kocjan T, Zacharieva S, Valdés N, Ambroziak U, Suzuki M, Detomas M, Puglisi S, Tucci L, Delivanis DA, Margaritopoulos D, Dusek T, Maggio R, Scaroni C, Concistrè A, Ronchi CL, Altieri B, Mosconi C, Diamantopoulos A, Iñiguez-Ariza NM, Vicennati V, Pia A, Kroiss M, Kaltsas G, Chrisoulidou A, Marina LV, Morelli V, Arlt W, Letizia C, Boscaro M, Stigliano A, Kastelan D, Tsagarakis S, Athimulam S, Pagotto U, Maeder U, Falhammar H, Newell-Price J, Terzolo M, Fassnacht M
Lancet Diabetes Endocrinol 2022 Jul;10(7):499-508. Epub 2022 May 6 doi: 10.1016/S2213-8587(22)00100-0. PMID: 35533704Free PMC Article
Feng Y, Mao ZG, Wang X, Du Q, Jian M, Zhu D, Xiao Z, Wang HJ, Zhu YH
Horm Metab Res 2018 Mar;50(3):179-192. Epub 2018 Jan 19 doi: 10.1055/s-0043-123763. PMID: 29351706
Liyanarachchi K, Ross R, Debono M
Best Pract Res Clin Endocrinol Metab 2017 Oct;31(5):459-473. Epub 2017 Nov 2 doi: 10.1016/j.beem.2017.10.011. PMID: 29223281
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Recent systematic reviews

Yearley AG, Chalif EJ, Gupta S, Chalif JI, Bernstock JD, Nawabi N, Arnaout O, Smith TR, Reardon DA, Laws ER
Pituitary 2023 Oct;26(5):561-572. Epub 2023 Jul 31 doi: 10.1007/s11102-023-01341-4. PMID: 37523025
Feola T, Gianno F, De Angelis M, Colonnese C, Esposito V, Giangaspero F, Jaffrain-Rea ML
J Endocrinol Invest 2021 Oct;44(10):2103-2122. Epub 2021 May 3 doi: 10.1007/s40618-021-01577-6. PMID: 33939106Free PMC Article
Zamanipoor Najafabadi AH, Zandbergen IM, de Vries F, Broersen LHA, van den Akker-van Marle ME, Pereira AM, Peul WC, Dekkers OM, van Furth WR, Biermasz NR
J Clin Endocrinol Metab 2020 Mar 1;105(3):e32-41. doi: 10.1210/clinem/dgz144. PMID: 31665485Free PMC Article
Seltzer J, Ashton CE, Scotton TC, Pangal D, Carmichael JD, Zada G
Neurosurg Focus 2015 Feb;38(2):E17. doi: 10.3171/2014.10.FOCUS14683. PMID: 25639319
He W, Chen F, Dalm B, Kirby PA, Greenlee JD
Pituitary 2015 Feb;18(1):159-68. doi: 10.1007/s11102-014-0552-2. PMID: 24445565

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