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Neonatal Chemical Conjunctivitis

MedGen UID:
852422
•Concept ID:
C0149866
•
Disease or Syndrome

Definition

Inflammation of the conjunctiva in a newborn due to chemical irritation which was acquired postnatally from iatrogenic causes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeonatal Chemical Conjunctivitis

Professional guidelines

PubMed

Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article
Neonatal chlamydial infections: prevention and treatment.
Zar HJ
Paediatr Drugs 2005;7(2):103-10. doi: 10.2165/00148581-200507020-00003. PMID: 15871630
Conjunctivitis in children. A refresher survey of diagnosis and contemporary treatment.
Moore RA, Schmitt BD
Clin Pediatr (Phila) 1979 Jan;18(1):26-30, 32. doi: 10.1177/000992287901800103. PMID: 365427

Recent clinical studies

Etiology

Epidemiological Investigation and Risk Factor Analysis of Acute Hemorrhagic Conjunctivitis in Huangshi Port District, Huangshi City.
Liu J, Zhang H
Comput Math Methods Med 2022;2022:3009589. Epub 2022 May 2 doi: 10.1155/2022/3009589. PMID: 35547568Free PMC Article
Prophylaxis for ophthalmia neonatorum in Brazil: A snapshot using a multi-professional national survey.
Miralha AL, Chermont AG, Orlandi PP, Rugolo LS, Sant'Anna G
J Neonatal Perinatal Med 2021;14(2):203-211. doi: 10.3233/NPM-200503. PMID: 32894255
Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article
Ophthalmia neonatorum: what kind of prophylaxis?
Zuppa AA, D'Andrea V, Catenazzi P, Scorrano A, Romagnoli C
J Matern Fetal Neonatal Med 2011 Jun;24(6):769-73. doi: 10.3109/14767058.2010.531326. PMID: 21534852
Neonatal chlamydial infections: prevention and treatment.
Zar HJ
Paediatr Drugs 2005;7(2):103-10. doi: 10.2165/00148581-200507020-00003. PMID: 15871630

Diagnosis

Neonatal ophthalmia in the developing world. Epidemiology, etiology, management and control.
Fransen L, Klauss V
Int Ophthalmol 1988 Jan;11(3):189-96. doi: 10.1007/BF00130622. PMID: 3047073
Conjunctivitis in children.
Fisher MC
Pediatr Clin North Am 1987 Dec;34(6):1447-56. doi: 10.1016/s0031-3955(16)36367-2. PMID: 3317240
Silver nitrate prophylaxis.
Schneider G
Can Med Assoc J 1984 Aug 1;131(3):193-6. PMID: 6378348Free PMC Article
Conjunctivitis in children. A refresher survey of diagnosis and contemporary treatment.
Moore RA, Schmitt BD
Clin Pediatr (Phila) 1979 Jan;18(1):26-30, 32. doi: 10.1177/000992287901800103. PMID: 365427
Ophthalmia neonatorum: a chart review.
Armstrong JH, Zacarias F, Rein MF
Pediatrics 1976 Jun;57(6):884-92. PMID: 819900

Therapy

Ophthalmia neonatorum: what kind of prophylaxis?
Zuppa AA, D'Andrea V, Catenazzi P, Scorrano A, Romagnoli C
J Matern Fetal Neonatal Med 2011 Jun;24(6):769-73. doi: 10.3109/14767058.2010.531326. PMID: 21534852
Neonatal conjunctivitis.
Grosskreutz C, Smith LB
Int Ophthalmol Clin 1992 Winter;32(1):71-9. doi: 10.1097/00004397-199203210-00008. PMID: 1537666
Tetracyclines in ophthalmology.
Salamon SM
Surv Ophthalmol 1985 Jan-Feb;29(4):265-75. PMID: 3157226
Silver nitrate prophylaxis.
Schneider G
Can Med Assoc J 1984 Aug 1;131(3):193-6. PMID: 6378348Free PMC Article
Ophthalmia neonatorum.
Friendly DS
Pediatr Clin North Am 1983 Dec;30(6):1033-42. doi: 10.1016/s0031-3955(16)34500-x. PMID: 6359042

Prognosis

Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article
Neonatal chlamydial infections: prevention and treatment.
Zar HJ
Paediatr Drugs 2005;7(2):103-10. doi: 10.2165/00148581-200507020-00003. PMID: 15871630
From suspicion to action: the chemical conjunctivitis and silver nitrate connexion example in Brazilian hospitals.
Napchan BM, Morales RP, Carvalho ML, Cunha KV, Figueras A
Pharmacoepidemiol Drug Saf 2005 Aug;14(8):555-9. doi: 10.1002/pds.1050. PMID: 15565728
Maternal and infant use of erythromycin and other macrolide antibiotics as risk factors for infantile hypertrophic pyloric stenosis.
Mahon BE, Rosenman MB, Kleiman MB
J Pediatr 2001 Sep;139(3):380-4. doi: 10.1067/mpd.2001.117577. PMID: 11562617
Treatment of TRIC infection of the eye with rifampicin or chloramphenicol.
Darougar S, Viswalingam M, Treharne JD, Kinnison JR, Jones BR
Br J Ophthalmol 1977 Apr;61(4):255-9. doi: 10.1136/bjo.61.4.255. PMID: 322700Free PMC Article

Clinical prediction guides

Epidemiological Investigation and Risk Factor Analysis of Acute Hemorrhagic Conjunctivitis in Huangshi Port District, Huangshi City.
Liu J, Zhang H
Comput Math Methods Med 2022;2022:3009589. Epub 2022 May 2 doi: 10.1155/2022/3009589. PMID: 35547568Free PMC Article
Safety of topical ophthalmic antibiotics in pregnant women with hordeola, chalazia, blepharitis, or bacterial conjunctivitis: propensity score analyses.
Hashimoto Y, Michihata N, Yamana H, Shigemi D, Morita K, Matsui H, Yasunaga H, Aihara M
Eye (Lond) 2022 May;36(5):1066-1073. Epub 2021 May 25 doi: 10.1038/s41433-021-01586-y. PMID: 34035495Free PMC Article
Exposure to house dust phthalates in relation to asthma and allergies in both children and adults.
Ait Bamai Y, Shibata E, Saito I, Araki A, Kanazawa A, Morimoto K, Nakayama K, Tanaka M, Takigawa T, Yoshimura T, Chikara H, Saijo Y, Kishi R
Sci Total Environ 2014 Jul 1;485-486:153-163. Epub 2014 Apr 3 doi: 10.1016/j.scitotenv.2014.03.059. PMID: 24704966
Prophylaxis of ophthalmia neonatorum--a nationwide survey of the current practice in Austria.
Assadian O, Assadian A, Aspöck C, Hahn D, Koller W
Wien Klin Wochenschr 2002 Mar 28;114(5-6):194-9. PMID: 12238308
Ophthalmia neonatorum: study of a decade of experience at the Mount Sinai Hospital.
Jarvis VN, Levine R, Asbell PA
Br J Ophthalmol 1987 Apr;71(4):295-300. doi: 10.1136/bjo.71.4.295. PMID: 3580342Free PMC Article

Recent systematic reviews

Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Zikic A, Schünemann H, Wi T, Lincetto O, Broutet N, Santesso N
J Pediatric Infect Dis Soc 2018 Aug 17;7(3):e107-e115. doi: 10.1093/jpids/piy060. PMID: 30007329Free PMC Article

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