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Adult Myelodysplastic Syndrome

MedGen UID:
859692
Concept ID:
C3900098
Neoplastic Process

Definition

Myelodysplastic syndrome that occurs in adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Myelodysplastic Syndrome

Professional guidelines

PubMed

Enjeti AK, Agarwal R, Blombery P, Chee L, Chua CC, Grigg A, Hamad N, Iland H, Lane S, Perkins A, Singhal D, Tate C, Tiong IS, Ross DM
Pathology 2022 Jun;54(4):389-398. Epub 2022 Apr 20 doi: 10.1016/j.pathol.2022.03.002. PMID: 35461716

Recent clinical studies

Etiology

Badar T, Chlon T
Curr Hematol Malig Rep 2022 Oct;17(5):113-120. Epub 2022 Jul 4 doi: 10.1007/s11899-022-00667-3. PMID: 35781188Free PMC Article
Konuma T, Aoki J, Ozawa Y, Uchida N, Kobayashi T, Onizuka M, Katayama Y, Ohta T, Nakano N, Ota S, Onishi Y, Kobayashi H, Fukuda T, Kanda Y, Atsuta Y; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Transplant Cell Ther 2021 Aug;27(8):671-678. Epub 2021 May 12 doi: 10.1016/j.jtct.2021.05.003. PMID: 33991723
Konuma T, Ishiyama K, Igarashi A, Uchida N, Ozawa Y, Fukuda T, Ueda Y, Matsuoka KI, Mori T, Katayama Y, Onizuka M, Ichinohe T, Atsuta Y; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Clin Cancer Res 2020 Dec 15;26(24):6483-6493. Epub 2020 Sep 6 doi: 10.1158/1078-0432.CCR-20-1104. PMID: 32895232
Konuma T, Miyazaki Y, Uchida N, Ohashi K, Kondo T, Nakamae H, Takahashi S, Mori T, Ozawa Y, Kato C, Iwato K, Fukuda T, Ichinohe T, Atsuta Y, Ishiyama K; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Biol Blood Marrow Transplant 2017 Jan;23(1):75-80. Epub 2016 Oct 21 doi: 10.1016/j.bbmt.2016.10.015. PMID: 27777139
Björk J, Albin M, Mauritzson N, Strömberg U, Johansson B, Hagmar L
Epidemiology 2000 May;11(3):285-91. doi: 10.1097/00001648-200005000-00010. PMID: 10784245

Diagnosis

Konishi T, Matsuda K, Itonaga H, Doki N, Nishida T, Matsuoka KI, Ikeda T, Kanda Y, Fukuda T, Kanda J, Nakamae H, Imada K, Ueda Y, Ichinohe T, Atsuta Y, Ishiyama K
Transplant Cell Ther 2024 Jul;30(7):685.e1-685.e12. Epub 2024 Apr 30 doi: 10.1016/j.jtct.2024.04.019. PMID: 38697293
Enjeti AK, Agarwal R, Blombery P, Chee L, Chua CC, Grigg A, Hamad N, Iland H, Lane S, Perkins A, Singhal D, Tate C, Tiong IS, Ross DM
Pathology 2022 Jun;54(4):389-398. Epub 2022 Apr 20 doi: 10.1016/j.pathol.2022.03.002. PMID: 35461716
Hirsch CM, Przychodzen BP, Radivoyevitch T, Patel B, Thota S, Clemente MJ, Nagata Y, LaFramboise T, Carraway HE, Nazha A, Sekeres MA, Makishima H, Maciejewski JP
Haematologica 2017 Jun;102(6):1028-1034. Epub 2017 Mar 2 doi: 10.3324/haematol.2016.159772. PMID: 28255022Free PMC Article
Niemeyer CM, Kratz CP, Hasle H
Curr Treat Options Oncol 2005 May;6(3):209-14. doi: 10.1007/s11864-005-0004-3. PMID: 15869732
Björk J, Albin M, Mauritzson N, Strömberg U, Johansson B, Hagmar L
Epidemiology 2000 May;11(3):285-91. doi: 10.1097/00001648-200005000-00010. PMID: 10784245

Therapy

Konishi T, Matsuda K, Itonaga H, Doki N, Nishida T, Matsuoka KI, Ikeda T, Kanda Y, Fukuda T, Kanda J, Nakamae H, Imada K, Ueda Y, Ichinohe T, Atsuta Y, Ishiyama K
Transplant Cell Ther 2024 Jul;30(7):685.e1-685.e12. Epub 2024 Apr 30 doi: 10.1016/j.jtct.2024.04.019. PMID: 38697293
Konuma T, Ishiyama K, Igarashi A, Uchida N, Ozawa Y, Fukuda T, Ueda Y, Matsuoka KI, Mori T, Katayama Y, Onizuka M, Ichinohe T, Atsuta Y; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Clin Cancer Res 2020 Dec 15;26(24):6483-6493. Epub 2020 Sep 6 doi: 10.1158/1078-0432.CCR-20-1104. PMID: 32895232
Konuma T, Takahashi S, Uchida N, Kuwatsuka Y, Yamasaki S, Aoki J, Onishi Y, Aotsuka N, Ohashi K, Mori T, Masuko M, Nakamae H, Miyamura K, Kato K, Atsuta Y, Kato S, Asano S, Takami A, Miyazaki Y; Adult Myelodysplastic Syndrome and Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation
Biol Blood Marrow Transplant 2015 Sep;21(9):1632-40. Epub 2015 May 16 doi: 10.1016/j.bbmt.2015.05.009. PMID: 25985920
Mathew P, Gerbing R, Alonzo TA, Wallas T, Gong JZ, Jasty R, Jorstad DT, Raimondi SC, Chavez CM, Eisenberg NL, Hirsch B, Gamis A, Smith FO, Arceci RJ
Pediatr Blood Cancer 2011 Dec 15;57(7):1230-2. Epub 2011 Jun 16 doi: 10.1002/pbc.23164. PMID: 21681928
Niemeyer CM, Kratz CP, Hasle H
Curr Treat Options Oncol 2005 May;6(3):209-14. doi: 10.1007/s11864-005-0004-3. PMID: 15869732

Prognosis

Badar T, Chlon T
Curr Hematol Malig Rep 2022 Oct;17(5):113-120. Epub 2022 Jul 4 doi: 10.1007/s11899-022-00667-3. PMID: 35781188Free PMC Article
Konuma T, Aoki J, Ozawa Y, Uchida N, Kobayashi T, Onizuka M, Katayama Y, Ohta T, Nakano N, Ota S, Onishi Y, Kobayashi H, Fukuda T, Kanda Y, Atsuta Y; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Transplant Cell Ther 2021 Aug;27(8):671-678. Epub 2021 May 12 doi: 10.1016/j.jtct.2021.05.003. PMID: 33991723
Konuma T, Ishiyama K, Igarashi A, Uchida N, Ozawa Y, Fukuda T, Ueda Y, Matsuoka KI, Mori T, Katayama Y, Onizuka M, Ichinohe T, Atsuta Y; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Clin Cancer Res 2020 Dec 15;26(24):6483-6493. Epub 2020 Sep 6 doi: 10.1158/1078-0432.CCR-20-1104. PMID: 32895232
Konuma T, Miyazaki Y, Uchida N, Ohashi K, Kondo T, Nakamae H, Takahashi S, Mori T, Ozawa Y, Kato C, Iwato K, Fukuda T, Ichinohe T, Atsuta Y, Ishiyama K; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Biol Blood Marrow Transplant 2017 Jan;23(1):75-80. Epub 2016 Oct 21 doi: 10.1016/j.bbmt.2016.10.015. PMID: 27777139
Li P, Ji M, Lu F, Zhang J, Li H, Cui T, Li Wang X, Tang D, Ji C
Exp Cell Res 2014 Sep 10;327(1):48-56. Epub 2014 May 29 doi: 10.1016/j.yexcr.2014.05.013. PMID: 24880125

Clinical prediction guides

Konishi T, Matsuda K, Itonaga H, Doki N, Nishida T, Matsuoka KI, Ikeda T, Kanda Y, Fukuda T, Kanda J, Nakamae H, Imada K, Ueda Y, Ichinohe T, Atsuta Y, Ishiyama K
Transplant Cell Ther 2024 Jul;30(7):685.e1-685.e12. Epub 2024 Apr 30 doi: 10.1016/j.jtct.2024.04.019. PMID: 38697293
Konuma T, Miyazaki Y, Uchida N, Ohashi K, Kondo T, Nakamae H, Takahashi S, Mori T, Ozawa Y, Kato C, Iwato K, Fukuda T, Ichinohe T, Atsuta Y, Ishiyama K; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation
Biol Blood Marrow Transplant 2017 Jan;23(1):75-80. Epub 2016 Oct 21 doi: 10.1016/j.bbmt.2016.10.015. PMID: 27777139
Oliveira AF, Tansini A, Vidal DO, Lopes LF, Metze K, Lorand-Metze I
Pediatr Blood Cancer 2017 Apr;64(4) Epub 2016 Oct 17 doi: 10.1002/pbc.26285. PMID: 27748021
Varma N, Varma S
Indian J Pathol Microbiol 2008 Jan-Mar;51(1):97-101. doi: 10.4103/0377-4929.40416. PMID: 18417875
Chatterjee T, Dixit A, Mohapatra M, Tyagi S, Gupta PK, Mishra P, Bhattacharya M, Karan AS, Pati HP, Saxena R, Choudhry VP
Eur J Haematol 2004 Aug;73(2):93-7. doi: 10.1111/j.1600-0609.2004.00271.x. PMID: 15245507

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