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Abnormality of the anterior commissure

MedGen UID:
868134
Concept ID:
C4022525
Anatomical Abnormality
HPO: HP:0030301

Definition

An anomaly of the anterior commissure, a bundle of nerve fibers that connect the two cerebral hemispheres across the midline. The anterior commissure plays a role in pain sensation and contains decussating fibers from the olfactory tracts. [from HPO]

Conditions with this feature

Gaze palsy, familial horizontal, with progressive scoliosis, 2
MedGen UID:
1393733
Concept ID:
C4479640
Disease or Syndrome

Professional guidelines

PubMed

Chen S, Gong H, Huang N, Yang F, Wang M
Acta Otolaryngol 2023 Sep;143(9):823-828. Epub 2023 Nov 8 doi: 10.1080/00016489.2023.2265436. PMID: 37837405
Cao Y, Sun G
Ann Otol Rhinol Laryngol 2018 Dec;127(12):946-952. Epub 2018 Sep 29 doi: 10.1177/0003489418803651. PMID: 30269514
Glastonbury CM, Osborn AG, Salzman KL
Radiographics 2011 Nov-Dec;31(7):1889-905. doi: 10.1148/rg.317115083. PMID: 22084178

Recent clinical studies

Etiology

Moser C, Spencer-Smith MM, Anderson PJ, McIlroy A, Wood AG, Leventer RJ, Anderson VA, Siffredi V
Brain Lang 2024 Aug;255:105448. Epub 2024 Jul 30 doi: 10.1016/j.bandl.2024.105448. PMID: 39083998
Martín-González E, Prados-Pardo Á, Sawiak SJ, Dalley JW, Padro D, Ramos-Cabrer P, Mora S, Moreno-Montoya M
Behav Brain Funct 2023 Nov 6;19(1):19. doi: 10.1186/s12993-023-00221-y. PMID: 37932782Free PMC Article
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
Koepp MJ, Duncan JS
Curr Opin Neurol 2004 Aug;17(4):467-74. doi: 10.1097/01.wco.0000137539.91738.2b. PMID: 15247544
Zivković SM
Urology 1981 May;17(5):467-8. doi: 10.1016/0090-4295(81)90193-x. PMID: 7233663

Diagnosis

Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
Lavrador JP, Ferreira V, Lourenço M, Alexandre I, Rocha M, Oliveira E, Kailaya-Vasan A, Neto L
Surg Radiol Anat 2019 Jun;41(6):613-624. Epub 2019 May 22 doi: 10.1007/s00276-019-02218-7. PMID: 31119409
Nicollas R, Triglia JM
Otolaryngol Clin North Am 2008 Oct;41(5):877-88, viii. doi: 10.1016/j.otc.2008.04.008. PMID: 18775339
Koepp MJ, Duncan JS
Curr Opin Neurol 2004 Aug;17(4):467-74. doi: 10.1097/01.wco.0000137539.91738.2b. PMID: 15247544
Zivković SM
Urology 1981 May;17(5):467-8. doi: 10.1016/0090-4295(81)90193-x. PMID: 7233663

Therapy

Peters JJ, Jacobs K, Munill M, Top APC, Stevens MF, Ronde EM, Don Griot JPW, Lachkar N, Breugem CC
J Craniofac Surg 2024 Jul-Aug 01;35(5):1356-1363. Epub 2024 Jun 11 doi: 10.1097/SCS.0000000000010343. PMID: 38861198Free PMC Article
Nam HH, Flynn M, Lasso A, Herz C, Sabin P, Wang Y, Cianciulli A, Vigil C, Huang J, Vicory J, Paniagua B, Allemang D, Goldberg DJ, Nuri M, Cohen MS, Fichtinger G, Jolley MA
Circ Cardiovasc Imaging 2023 Mar;16(3):e014671. Epub 2023 Mar 3 doi: 10.1161/CIRCIMAGING.122.014671. PMID: 36866669Free PMC Article
Kilroy E, Gerbella M, Cao L, Molfese P, Butera C, Harrison L, Jayashankar A, Rizzolatti G, Aziz-Zadeh L
Sci Rep 2022 Nov 14;12(1):19246. doi: 10.1038/s41598-022-21538-0. PMID: 36376319Free PMC Article
Nwonu CNS
West Afr J Med 2022 Oct 20;39(10):1075-1983. PMID: 36260866
Koutourousiou M, Filho FV, Costacou T, Fernandez-Miranda JC, Wang EW, Snyderman CH, Rothfus WE, Gardner PA
J Neurosurg 2014 Aug;121(2):359-66. Epub 2014 Feb 7 doi: 10.3171/2013.12.JNS13756. PMID: 24506240

Prognosis

Kitano R, Madan N, Mikami T, Madankumar R, Skotko BG, Santoro S, Ralston SJ, Bianchi DW, Tarui T
Prenat Diagn 2023 Oct;43(11):1450-1458. Epub 2023 Sep 12 doi: 10.1002/pd.6436. PMID: 37698481
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
Rönnerfalk M, Tamás É
Interact Cardiovasc Thorac Surg 2015 Jul;21(1):71-6. Epub 2015 Apr 2 doi: 10.1093/icvts/ivv072. PMID: 25840434
Lacour-Gayet F
Cardiol Young 2012 Dec;22(6):739-44. doi: 10.1017/S1047951112001564. PMID: 23331596
Zivković SM
Urology 1981 May;17(5):467-8. doi: 10.1016/0090-4295(81)90193-x. PMID: 7233663

Clinical prediction guides

Kaiyrzhanov R, Rad A, Lin SJ, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Karimiani EG, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Tayfun GA, Al Saman A, Alswaid A, Amiri N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Monajemi GB, Mohammadi P, Samie S, Banu SH, Pinto Basto J, Kortüm F, Bauer M, Bauer P, Beetz C, Garshasbi M, Issa AH, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D, Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW, Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M, Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R
Brain 2024 Apr 4;147(4):1436-1456. doi: 10.1093/brain/awad380. PMID: 37951597Free PMC Article
Kitano R, Madan N, Mikami T, Madankumar R, Skotko BG, Santoro S, Ralston SJ, Bianchi DW, Tarui T
Prenat Diagn 2023 Oct;43(11):1450-1458. Epub 2023 Sep 12 doi: 10.1002/pd.6436. PMID: 37698481
Dobyns WB, Aldinger KA, Ishak GE, Mirzaa GM, Timms AE, Grout ME, Dremmen MHG, Schot R, Vandervore L, van Slegtenhorst MA, Wilke M, Kasteleijn E, Lee AS, Barry BJ, Chao KR, Szczałuba K, Kobori J, Hanson-Kahn A, Bernstein JA, Carr L, D'Arco F, Miyana K, Okazaki T, Saito Y, Sasaki M, Das S, Wheeler MM, Bamshad MJ, Nickerson DA; University of Washington Center for Mendelian Genomics; Center for Mendelian Genomics at the Broad Institute of MIT and Harvard, Engle EC, Verheijen FW, Doherty D, Mancini GMS
Am J Hum Genet 2018 Dec 6;103(6):1009-1021. Epub 2018 Nov 21 doi: 10.1016/j.ajhg.2018.10.019. PMID: 30471716Free PMC Article
Romaniello R, Arrigoni F, Fry AE, Bassi MT, Rees MI, Borgatti R, Pilz DT, Cushion TD
Eur J Med Genet 2018 Dec;61(12):744-754. Epub 2018 Jul 17 doi: 10.1016/j.ejmg.2018.07.012. PMID: 30016746
Romaniello R, Arrigoni F, Bassi MT, Borgatti R
Brain Dev 2015 Mar;37(3):273-80. Epub 2014 Jul 5 doi: 10.1016/j.braindev.2014.06.002. PMID: 25008804

Recent systematic reviews

Dahan Z, Pincivy A, Nhan C, Bergeron M
J Otolaryngol Head Neck Surg 2024 Jan-Dec;53:19160216241266570. doi: 10.1177/19160216241266570. PMID: 39138869Free PMC Article
Mancuso L, Uddin LQ, Nani A, Costa T, Cauda F
Neurosci Biobehav Rev 2019 Oct;105:231-248. Epub 2019 Aug 11 doi: 10.1016/j.neubiorev.2019.07.004. PMID: 31412269
Duarte JA, de Araújo E Silva JQ, Goldani AA, Massuda R, Gama CS
Braz J Psychiatry 2016 Mar 22;38(2):167-75. doi: 10.1590/1516-4446-2015-1793. PMID: 27007148Free PMC Article

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