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Splanchnic vein thrombosis

MedGen UID:
868168
•Concept ID:
C4022560
•
Disease or Syndrome
Synonyms: Blood clot in splanchnic vein; Splanchnic Vein Thrombosis; SVT - splanchnic vein thrombosis; Thrombosis of splanchnic vein
SNOMED CT: SVT - splanchnic vein thrombosis (1293122004); Thrombosis of splanchnic vein (1293122004)
 
HPO: HP:0030247

Definition

The term splanchnic vein thrombosis encompasses Budd-Chiari syndrome (hepatic vein thrombosis), extrahepatic portal vein obstruction (EHPVO), and mesenteric vein thrombosis; the word splanchnic is used to refer to the visceral organs (of the abdominal cavity). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSplanchnic vein thrombosis

Professional guidelines

PubMed

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
Am J Hematol 2023 Sep;98(9):1465-1487. Epub 2023 Jun 26 doi: 10.1002/ajh.27002. PMID: 37357958
Treatment of portal vein thrombosis: an updated narrative review.
Caiano LM, Riva N, Carrier M, Gatt A, Ageno W
Minerva Med 2021 Dec;112(6):713-725. Epub 2021 Apr 9 doi: 10.23736/S0026-4806.21.07526-1. PMID: 33832217

Recent clinical studies

Etiology

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
How to manage splanchnic vein thrombosis in patients with liver disease.
Riva N, Ageno W
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):281-288. doi: 10.1182/hematology.2023000481. PMID: 38066910Free PMC Article
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
Am J Hematol 2023 Sep;98(9):1465-1487. Epub 2023 Jun 26 doi: 10.1002/ajh.27002. PMID: 37357958
Baveno VII - Renewing consensus in portal hypertension.
de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty
J Hepatol 2022 Apr;76(4):959-974. Epub 2021 Dec 30 doi: 10.1016/j.jhep.2021.12.022. PMID: 35120736Free PMC Article
Polycythemia vera: historical oversights, diagnostic details, and therapeutic views.
Tefferi A, Vannucchi AM, Barbui T
Leukemia 2021 Dec;35(12):3339-3351. Epub 2021 Sep 3 doi: 10.1038/s41375-021-01401-3. PMID: 34480106Free PMC Article

Diagnosis

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
How to manage splanchnic vein thrombosis in patients with liver disease.
Riva N, Ageno W
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):281-288. doi: 10.1182/hematology.2023000481. PMID: 38066910Free PMC Article
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
Am J Hematol 2023 Sep;98(9):1465-1487. Epub 2023 Jun 26 doi: 10.1002/ajh.27002. PMID: 37357958
Baveno VII - Renewing consensus in portal hypertension.
de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty
J Hepatol 2022 Apr;76(4):959-974. Epub 2021 Dec 30 doi: 10.1016/j.jhep.2021.12.022. PMID: 35120736Free PMC Article
Polycythemia vera: historical oversights, diagnostic details, and therapeutic views.
Tefferi A, Vannucchi AM, Barbui T
Leukemia 2021 Dec;35(12):3339-3351. Epub 2021 Sep 3 doi: 10.1038/s41375-021-01401-3. PMID: 34480106Free PMC Article

Therapy

How to manage splanchnic vein thrombosis in patients with liver disease.
Riva N, Ageno W
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):281-288. doi: 10.1182/hematology.2023000481. PMID: 38066910Free PMC Article
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
Am J Hematol 2023 Sep;98(9):1465-1487. Epub 2023 Jun 26 doi: 10.1002/ajh.27002. PMID: 37357958
Cancer-Associated Splanchnic Vein Thrombosis.
Cohen O, Caiano LM, Tufano A, Ageno W
Semin Thromb Hemost 2021 Nov;47(8):931-941. Epub 2021 Jun 11 doi: 10.1055/s-0040-1722607. PMID: 34116580
Treatment of portal vein thrombosis: an updated narrative review.
Caiano LM, Riva N, Carrier M, Gatt A, Ageno W
Minerva Med 2021 Dec;112(6):713-725. Epub 2021 Apr 9 doi: 10.23736/S0026-4806.21.07526-1. PMID: 33832217
Anticoagulant therapy for splanchnic vein thrombosis: ISTH SSC Subcommittee Control of Anticoagulation.
Di Nisio M, Valeriani E, Riva N, Schulman S, Beyer-Westendorf J, Ageno W
J Thromb Haemost 2020 Jul;18(7):1562-1568. doi: 10.1111/jth.14836. PMID: 32619346

Prognosis

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
How to manage splanchnic vein thrombosis in patients with liver disease.
Riva N, Ageno W
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):281-288. doi: 10.1182/hematology.2023000481. PMID: 38066910Free PMC Article
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
Am J Hematol 2023 Sep;98(9):1465-1487. Epub 2023 Jun 26 doi: 10.1002/ajh.27002. PMID: 37357958
Baveno VII - Renewing consensus in portal hypertension.
de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty
J Hepatol 2022 Apr;76(4):959-974. Epub 2021 Dec 30 doi: 10.1016/j.jhep.2021.12.022. PMID: 35120736Free PMC Article
Polycythemia vera: historical oversights, diagnostic details, and therapeutic views.
Tefferi A, Vannucchi AM, Barbui T
Leukemia 2021 Dec;35(12):3339-3351. Epub 2021 Sep 3 doi: 10.1038/s41375-021-01401-3. PMID: 34480106Free PMC Article

Clinical prediction guides

Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
Am J Hematol 2023 Sep;98(9):1465-1487. Epub 2023 Jun 26 doi: 10.1002/ajh.27002. PMID: 37357958
Cancer-Associated Splanchnic Vein Thrombosis.
Cohen O, Caiano LM, Tufano A, Ageno W
Semin Thromb Hemost 2021 Nov;47(8):931-941. Epub 2021 Jun 11 doi: 10.1055/s-0040-1722607. PMID: 34116580
Splanchnic Vein Thrombosis: Current Perspectives.
Valeriani E, Riva N, Di Nisio M, Ageno W
Vasc Health Risk Manag 2019;15:449-461. Epub 2019 Oct 22 doi: 10.2147/VHRM.S197732. PMID: 31695400Free PMC Article
Safety and Efficacy of Dabigatran Etexilate vs Dose-Adjusted Warfarin in Patients With Cerebral Venous Thrombosis: A Randomized Clinical Trial.
Ferro JM, Coutinho JM, Dentali F, Kobayashi A, Alasheev A, Canhão P, Karpov D, Nagel S, Posthuma L, Roriz JM, Caria J, Frässdorf M, Huisman H, Reilly P, Diener HC; RE-SPECT CVT Study Group
JAMA Neurol 2019 Dec 1;76(12):1457-1465. doi: 10.1001/jamaneurol.2019.2764. PMID: 31479105Free PMC Article
Splanchnic vein thrombosis in myeloproliferative neoplasms: treatment algorithm 2018.
Finazzi G, De Stefano V, Barbui T
Blood Cancer J 2018 Jun 26;8(7):64. doi: 10.1038/s41408-018-0100-9. PMID: 29946154Free PMC Article

Recent systematic reviews

Therapeutic anticoagulation for splanchnic vein thrombosis in acute pancreatitis: A systematic review and meta-analysis.
Sissingh NJ, Groen JV, Koole D, Klok FA, Boekestijn B, Bollen TL, van Santvoort HC, Verdonk RC, Bonsing BA, van Eijck CHJ, van Hooft JE, Mieog JSD; Dutch Pancreatitis Study Group
Pancreatology 2022 Mar;22(2):235-243. Epub 2021 Dec 22 doi: 10.1016/j.pan.2021.12.008. PMID: 35012902
Acute splanchnic vein thrombosis in patients with COVID-19: A systematic review.
Buso G, Becchetti C, Berzigotti A
Dig Liver Dis 2021 Aug;53(8):937-949. Epub 2021 May 26 doi: 10.1016/j.dld.2021.05.021. PMID: 34120860Free PMC Article
Anticoagulant therapy for splanchnic vein thrombosis: a systematic review and meta-analysis.
Valeriani E, Di Nisio M, Riva N, Cohen O, Garcia-Pagan JC, Magaz M, Porreca E, Ageno W
Blood 2021 Mar 4;137(9):1233-1240. doi: 10.1182/blood.2020006827. PMID: 32911539
Cytomegalovirus-associated splanchnic vein thrombosis in immunocompetent patients: A systematic review.
Bertoni M, Squizzato A, Foretic M, Zanieri S, Di Natale ME
Thromb Res 2018 Aug;168:104-113. Epub 2018 Jun 21 doi: 10.1016/j.thromres.2018.06.015. PMID: 29960252
Associations of antiphospholipid antibodies with splanchnic vein thrombosis: a systematic review with meta-analysis.
Qi X, De Stefano V, Su C, Bai M, Guo X, Fan D
Medicine (Baltimore) 2015 Jan;94(4):e496. doi: 10.1097/MD.0000000000000496. PMID: 25634200Free PMC Article

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