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Abnormal labia minora morphology

MedGen UID:
868302
Concept ID:
C4022696
Anatomical Abnormality
Synonyms: Abnormality of the inner vaginal lips; Abnormality of the labia minora
 
HPO: HP:0012880

Definition

An anomaly of the labia minora, the folds of skin between the outer labia. [from HPO]

Professional guidelines

PubMed

Day T, Wilkinson E, Rowan D, Scurry J; ISSVD Difficult Pathologic Diagnoses Committee*
J Low Genit Tract Dis 2020 Jul;24(3):317-329. doi: 10.1097/LGT.0000000000000532. PMID: 32205763
Ge MM, Gao YY, Wu BB, Yan K, Qin Q, Wang H, Zhou W, Yang L
Mol Biol Rep 2019 Oct;46(5):4717-4724. Epub 2019 Jul 3 doi: 10.1007/s11033-019-04916-2. PMID: 31270759
de Munnik SA, Bicknell LS, Aftimos S, Al-Aama JY, van Bever Y, Bober MB, Clayton-Smith J, Edrees AY, Feingold M, Fryer A, van Hagen JM, Hennekam RC, Jansweijer MC, Johnson D, Kant SG, Opitz JM, Ramadevi AR, Reardon W, Ross A, Sarda P, Schrander-Stumpel CT, Schoots J, Temple IK, Terhal PA, Toutain A, Wise CA, Wright M, Skidmore DL, Samuels ME, Hoefsloot LH, Knoers NV, Brunner HG, Jackson AP, Bongers EM
Eur J Hum Genet 2012 Jun;20(6):598-606. Epub 2012 Feb 15 doi: 10.1038/ejhg.2011.269. PMID: 22333897Free PMC Article

Recent clinical studies

Etiology

Lykkebo AW, Drue HC, Lam JUH, Guldberg R
J Low Genit Tract Dis 2017 Jul;21(3):198-203. doi: 10.1097/LGT.0000000000000308. PMID: 28369012
Clerico C, Lari A, Mojallal A, Boucher F
Aesthetic Plast Surg 2017 Jun;41(3):714-719. Epub 2017 Mar 10 doi: 10.1007/s00266-017-0831-1. PMID: 28314908
de Munnik SA, Hoefsloot EH, Roukema J, Schoots J, Knoers NV, Brunner HG, Jackson AP, Bongers EM
Orphanet J Rare Dis 2015 Sep 17;10:114. doi: 10.1186/s13023-015-0322-x. PMID: 26381604Free PMC Article
Shetty MV, Bhaskaran A, Sen TK
Afr J Paediatr Surg 2011 May-Aug;8(2):215-7. doi: 10.4103/0189-6725.86066. PMID: 22005369
Michala L, Koliantzaki S, Antsaklis A
J Psychosom Obstet Gynaecol 2011 Sep;32(3):154-6. Epub 2011 Jun 23 doi: 10.3109/0167482X.2011.585726. PMID: 21696338

Diagnosis

Day T, Wilkinson E, Rowan D, Scurry J; ISSVD Difficult Pathologic Diagnoses Committee*
J Low Genit Tract Dis 2020 Jul;24(3):317-329. doi: 10.1097/LGT.0000000000000532. PMID: 32205763
Clerico C, Lari A, Mojallal A, Boucher F
Aesthetic Plast Surg 2017 Jun;41(3):714-719. Epub 2017 Mar 10 doi: 10.1007/s00266-017-0831-1. PMID: 28314908
de Munnik SA, Hoefsloot EH, Roukema J, Schoots J, Knoers NV, Brunner HG, Jackson AP, Bongers EM
Orphanet J Rare Dis 2015 Sep 17;10:114. doi: 10.1186/s13023-015-0322-x. PMID: 26381604Free PMC Article
Shetty MV, Bhaskaran A, Sen TK
Afr J Paediatr Surg 2011 May-Aug;8(2):215-7. doi: 10.4103/0189-6725.86066. PMID: 22005369
Reddy J, Laufer MR
J Pediatr Adolesc Gynecol 2010 Feb;23(1):3-6. Epub 2009 Jul 15 doi: 10.1016/j.jpag.2009.01.071. PMID: 19608442

Therapy

Oldzej J, Manazir J, Gold JA, Mahmoud R, Osann K, Flodman P, Cassidy SB, Kimonis VE
Am J Med Genet A 2020 Jan;182(1):169-175. Epub 2019 Nov 29 doi: 10.1002/ajmg.a.61408. PMID: 31782896
Acimi S, Bessahraoui M, Acimi MA, Abderrahmane N, Debbous L
Int Urol Nephrol 2019 Mar;51(3):395-399. Epub 2018 Dec 13 doi: 10.1007/s11255-018-2058-8. PMID: 30547360
Boulos S, Rubin AI, Yan AC, McMahon PJ, Perman MJ
Pediatr Dermatol 2018 May;35(3):e198-e199. Epub 2018 Mar 24 doi: 10.1111/pde.13467. PMID: 29573456
Farahani F, Gentry A, Lara-Torre E, McCuin E
J Low Genit Tract Dis 2015 Apr;19(2):e35-7. doi: 10.1097/LGT.0000000000000067. PMID: 25062401
Bouchard S, Yazbeck S, Lallier M
J Pediatr Surg 1999 Jul;34(7):1133-5. doi: 10.1016/s0022-3468(99)90584-5. PMID: 10442608

Prognosis

Ge MM, Gao YY, Wu BB, Yan K, Qin Q, Wang H, Zhou W, Yang L
Mol Biol Rep 2019 Oct;46(5):4717-4724. Epub 2019 Jul 3 doi: 10.1007/s11033-019-04916-2. PMID: 31270759
Lapalorcia LM, Podda S, Campiglio G, Cordellini M
Aesthetic Plast Surg 2013 Aug;37(4):711-4. Epub 2013 Jun 15 doi: 10.1007/s00266-013-0159-4. PMID: 23771244
Shetty MV, Bhaskaran A, Sen TK
Afr J Paediatr Surg 2011 May-Aug;8(2):215-7. doi: 10.4103/0189-6725.86066. PMID: 22005369
Ragan DC, Casale AJ, Rink RC, Cain MP, Weaver DD
J Urol 1999 Feb;161(2):622-5. PMID: 9915472
Christensen EH, Oster J
Acta Paediatr Scand 1971 Nov;60(6):709-15. doi: 10.1111/j.1651-2227.1971.tb07013.x. PMID: 5123501

Clinical prediction guides

Oranges CM, Sisti A, Sisti G
Aesthet Surg J 2015 May;35(4):419-31. doi: 10.1093/asj/sjv023. PMID: 25908699
Lesma A, Bocciardi A, Corti S, Chiumello G, Rigatti P, Montorsi F
J Urol 2014 Jan;191(1):206-11. Epub 2013 Aug 6 doi: 10.1016/j.juro.2013.07.097. PMID: 23933397
Lapalorcia LM, Podda S, Campiglio G, Cordellini M
Aesthetic Plast Surg 2013 Aug;37(4):711-4. Epub 2013 Jun 15 doi: 10.1007/s00266-013-0159-4. PMID: 23771244
Munhoz AM, Filassi JR, Ricci MD, Aldrighi C, Correia LD, Aldrighi JM, Ferreira MC
Plast Reconstr Surg 2006 Oct;118(5):1237-1247. doi: 10.1097/01.prs.0000237003.24294.04. PMID: 17016196
Shapiro E
J Urol 1999 Aug;162(2):530-3. PMID: 10411083

Recent systematic reviews

Carvalho C, Morandi A, Samuk I, Gine C, Gorter R, Martinez-Urrutia MJ, Vilanova-Sánchez A
Eur J Pediatr Surg 2024 Dec;34(6):482-487. Epub 2024 Jan 12 doi: 10.1055/a-2244-4551. PMID: 38216143

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