U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Basal encephalocele

MedGen UID:
868771
Concept ID:
C4023176
Congenital Abnormality
Synonym: basal encephalocele
SNOMED CT: Basal encephalocele (838339009)
 
HPO: HP:0011817
Monarch Initiative: MONDO:0017082
Orphanet: ORPHA268829

Definition

Basal encephalocele is an encephalocele that occurs along the cribriform plate or through the sphenoid bone. The mass may appear in the nasal cavity, nasopharynx, epipharynx, sphenoid sinus, posterior orbit, or pterygopalatine fossa. The important distinction from other types is that no external tumor is visible except in those rare instances of herniations so large that they protrude through the mouth or nares. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBasal encephalocele

Professional guidelines

PubMed

Dreizin D, Sakai O, Champ K, Gandhi D, Aarabi B, Nam AJ, Morales RE, Eisenman DJ
Radiographics 2021 May-Jun;41(3):762-782. Epub 2021 Apr 2 doi: 10.1148/rg.2021200189. PMID: 33797996
Tirumandas M, Sharma A, Gbenimacho I, Shoja MM, Tubbs RS, Oakes WJ, Loukas M
Childs Nerv Syst 2013 May;29(5):739-44. Epub 2012 Dec 18 doi: 10.1007/s00381-012-1998-z. PMID: 23247827
Chen CP
Taiwan J Obstet Gynecol 2007 Mar;46(1):9-14. doi: 10.1016/S1028-4559(08)60100-X. PMID: 17389183

Recent clinical studies

Etiology

Li AY, Gaebe K, Quon JL, Vescan A, James AL, Wolter NE
Otolaryngol Head Neck Surg 2024 Jul;171(1):23-34. Epub 2024 Mar 17 doi: 10.1002/ohn.711. PMID: 38494838
Crane-Smith Z, De Castro SCP, Nikolopoulou E, Wolujewicz P, Smedley D, Lei Y, Mather E, Santos C, Hopkinson M, Pitsillides AA; Genomics England Research Consortium, Finnell RH, Ross ME, Copp AJ, Greene NDE
Hum Mol Genet 2023 Aug 26;32(17):2681-2692. doi: 10.1093/hmg/ddad094. PMID: 37364051Free PMC Article
Morota N, Ihara S, Ogiwara H, Usami K, Tamada I, Kaneko T
J Neurosurg Pediatr 2021 Jan 1;27(1):69-78. Epub 2020 Oct 30 doi: 10.3171/2020.6.PEDS20315. PMID: 33126211
Nagaraj UD, Moudgal R, Hopkin RJ, Venkatesan C, Kline-Fath BM
Pediatr Radiol 2019 Dec;49(13):1843-1847. Epub 2019 Aug 5 doi: 10.1007/s00247-019-04491-5. PMID: 31384970
Yang Z, Wang Z, Wang B, Liu P
J Clin Neurosci 2015 Dec;22(12):1916-20. doi: 10.1016/j.jocn.2015.03.066. PMID: 26256066

Diagnosis

Wotipka EK, Karowadia KM, Davila PA, Laylani NA, Lee AG
J Neuroophthalmol 2024 Jun 1;44(2):e236-e237. Epub 2023 Jan 25 doi: 10.1097/WNO.0000000000001806. PMID: 36693126
Satija CE, Mehta VJ, Maltry AC, Nussbaum E, Nussbaum L, Harrison AR
Ophthalmic Plast Reconstr Surg 2020 Jan/Feb;36(1):e19-e21. doi: 10.1097/IOP.0000000000001508. PMID: 31895728
Guion-Almeida ML, Richieri-Costa A, Jehee FS, Passos-Bueno MR, Zechi-Ceide RM
Am J Med Genet A 2012 Jul;158A(7):1676-9. Epub 2012 May 24 doi: 10.1002/ajmg.a.35351. PMID: 22628242
Elster AD, Branch CL Jr
Radiology 1989 Jan;170(1 Pt 1):245-7. doi: 10.1148/radiology.170.1.2909104. PMID: 2909104
De Laey JJ, Ryckaert S, Leys A
Ophthalmic Paediatr Genet 1985 Feb;5(1-2):117-24. doi: 10.3109/13816818509007865. PMID: 3932911

Therapy

Guerra-Junior G, Spinola-Castro AM, Siviero-Miachon AA, Nogueira RG, Lemos-Marini SH, D'Souza-Li LF, Silva PC, França ES, Soardi FC, Mello MP
Arq Bras Endocrinol Metabol 2008 Nov;52(8):1221-7. doi: 10.1590/s0004-27302008000800004. PMID: 19169473
Esparza J, Hinojosa J, García-Recuero I, Romance A, Pascual B, Martínez de Aragón A
Neurocirugia (Astur) 2008 Dec;19(6):509-29. doi: 10.1016/s1130-1473(08)70201-x. PMID: 19112545
Gök A, Erkutlu I, Alptekin M, Kanlikama M
Acta Neurochir (Wien) 2004 Jan;146(1):53-6; discussion 56-7. Epub 2003 Dec 15 doi: 10.1007/s00701-003-0175-2. PMID: 14740265
Goldhammer Y, Smith JL
Arch Ophthalmol 1975 Feb;93(2):115-8. doi: 10.1001/archopht.1975.01010020121004. PMID: 1090290

Prognosis

Crane-Smith Z, De Castro SCP, Nikolopoulou E, Wolujewicz P, Smedley D, Lei Y, Mather E, Santos C, Hopkinson M, Pitsillides AA; Genomics England Research Consortium, Finnell RH, Ross ME, Copp AJ, Greene NDE
Hum Mol Genet 2023 Aug 26;32(17):2681-2692. doi: 10.1093/hmg/ddad094. PMID: 37364051Free PMC Article
Morota N, Ihara S, Ogiwara H, Usami K, Tamada I, Kaneko T
J Neurosurg Pediatr 2021 Jan 1;27(1):69-78. Epub 2020 Oct 30 doi: 10.3171/2020.6.PEDS20315. PMID: 33126211
Nagaraj UD, Moudgal R, Hopkin RJ, Venkatesan C, Kline-Fath BM
Pediatr Radiol 2019 Dec;49(13):1843-1847. Epub 2019 Aug 5 doi: 10.1007/s00247-019-04491-5. PMID: 31384970
Yang Z, Wang Z, Wang B, Liu P
J Clin Neurosci 2015 Dec;22(12):1916-20. doi: 10.1016/j.jocn.2015.03.066. PMID: 26256066
Morioka M, Marubayashi T, Masumitsu T, Miura M, Ushio Y
Brain Dev 1995 May-Jun;17(3):196-201. doi: 10.1016/0387-7604(95)00021-3. PMID: 7573760

Clinical prediction guides

Crane-Smith Z, De Castro SCP, Nikolopoulou E, Wolujewicz P, Smedley D, Lei Y, Mather E, Santos C, Hopkinson M, Pitsillides AA; Genomics England Research Consortium, Finnell RH, Ross ME, Copp AJ, Greene NDE
Hum Mol Genet 2023 Aug 26;32(17):2681-2692. doi: 10.1093/hmg/ddad094. PMID: 37364051Free PMC Article
Van Gompel JJ, Khan YA, Bloomfield EL, Pallanch JF, Atkinson JL
Surg Neurol 2009 Dec;72(6):757-60. Epub 2009 Jul 14 doi: 10.1016/j.surneu.2009.05.015. PMID: 19604548
Guerra-Junior G, Spinola-Castro AM, Siviero-Miachon AA, Nogueira RG, Lemos-Marini SH, D'Souza-Li LF, Silva PC, França ES, Soardi FC, Mello MP
Arq Bras Endocrinol Metabol 2008 Nov;52(8):1221-7. doi: 10.1590/s0004-27302008000800004. PMID: 19169473
De Laey JJ, Ryckaert S, Leys A
Ophthalmic Paediatr Genet 1985 Feb;5(1-2):117-24. doi: 10.3109/13816818509007865. PMID: 3932911

Recent systematic reviews

Li AY, Gaebe K, Quon JL, Vescan A, James AL, Wolter NE
Otolaryngol Head Neck Surg 2024 Jul;171(1):23-34. Epub 2024 Mar 17 doi: 10.1002/ohn.711. PMID: 38494838

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...