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Agenesis of premolar

MedGen UID:
869146
Concept ID:
C4023566
Finding
Synonyms: Absence of bicuspid; Absence of premolar; Agenesis of bicuspid; Failure of development of bicuspid; Failure of development of premolar; Missing bicuspid; Missing premolar
 
HPO: HP:0011051

Definition

Agenesis of premolar tooth. [from HPO]

Conditions with this feature

Otodental syndrome
MedGen UID:
318937
Concept ID:
C1833693
Disease or Syndrome
Otodental syndrome is an autosomal dominant condition characterized by grossly enlarged canine and molar teeth (globodontia), associated with sensorineural hearing loss. Ocular coloboma segregating with otodental syndrome has been reported (summary by Gregory-Evans et al., 2007).
Tooth agenesis, selective, X-linked, 1
MedGen UID:
410143
Concept ID:
C1970757
Disease or Syndrome
Any tooth agenesis in which the cause of the disease is a mutation in the EDA gene.

Professional guidelines

PubMed

Bossone E, Eagle KA
Nat Rev Cardiol 2021 May;18(5):331-348. Epub 2020 Dec 22 doi: 10.1038/s41569-020-00472-6. PMID: 33353985
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Morgan T
Am Fam Physician 2007 Aug 1;76(3):405-10. PMID: 17708142

Recent clinical studies

Etiology

Thiene G, Rizzo S, Basso C
Cardiovasc Pathol 2024 May-Jun;70:107604. Epub 2024 Jan 20 doi: 10.1016/j.carpath.2024.107604. PMID: 38253300
Bravo-Jaimes K, Prakash SK
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):398-406. Epub 2020 Jun 27 doi: 10.1016/j.pcad.2020.06.005. PMID: 32599026Free PMC Article
Sabatino J, Wicik Z, De Rosa S, Eyileten C, Jakubik D, Spaccarotella C, Mongiardo A, Postula M, Indolfi C
J Mol Cell Cardiol 2019 Sep;134:98-106. Epub 2019 Jul 3 doi: 10.1016/j.yjmcc.2019.07.001. PMID: 31278905
Shah SY, Higgins A, Desai MY
Cleve Clin J Med 2018 Oct;85(10):779-784. doi: 10.3949/ccjm.85a.17069. PMID: 30289756
Rølling S, Poulsen S
Acta Odontol Scand 2001 Apr;59(2):111-2. doi: 10.1080/000163501750157298. PMID: 11370748

Diagnosis

Lerdrungroj K, Banomyong D, Songtrakul K, Porkaew P, Nakornchai S
J Endod 2023 Oct;49(10):1230-1237. Epub 2023 Jul 26 doi: 10.1016/j.joen.2023.07.017. PMID: 37506764
Cotts TB, Salciccioli KB, Swanson SK, Yetman AT
Cardiol Clin 2020 Aug;38(3):325-336. Epub 2020 Jun 3 doi: 10.1016/j.ccl.2020.04.002. PMID: 32622488
Bravo-Jaimes K, Prakash SK
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):398-406. Epub 2020 Jun 27 doi: 10.1016/j.pcad.2020.06.005. PMID: 32599026Free PMC Article
Ehrlich T, de Kerchove L, Vojacek J, Boodhwani M, El-Hamamsy I, De Paulis R, Lansac E, Bavaria JE, El Khoury G, Schäfers HJ
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):457-464. Epub 2020 May 5 doi: 10.1016/j.pcad.2020.04.010. PMID: 32380025
Manka R, Binter C, Kozerke S
Lancet 2014 Dec 13;384(9960):2141. Epub 2014 Sep 18 doi: 10.1016/S0140-6736(14)60752-2. PMID: 25242035

Therapy

Jørgensen TH, Thyregod HGH, Savontaus M, Willemen Y, Bleie Ø, Tang M, Niemela M, Angerås O, Gudmundsdóttir IJ, Sartipy U, Dagnegaard H, Laine M, Rück A, Piuhola J, Petursson P, Christiansen EH, Malmberg M, Olsen PS, Haaverstad R, Sondergaard L, De Backer O; NOTION-2 investigators
Eur Heart J 2024 Oct 5;45(37):3804-3814. doi: 10.1093/eurheartj/ehae331. PMID: 38747246
Otto CM
Heart 2018 Nov;104(22):1807-1809. doi: 10.1136/heartjnl-2018-314232. PMID: 30366931
Perlman GY, Blanke P, Webb JG
EuroIntervention 2016 Sep 18;12(Y):Y42-5. doi: 10.4244/EIJV12SYA10. PMID: 27640030
Ladich E, Nakano M, Carter-Monroe N, Virmani R
Future Cardiol 2011 Sep;7(5):629-42. doi: 10.2217/fca.11.53. PMID: 21929343
Morgan T
Am Fam Physician 2007 Aug 1;76(3):405-10. PMID: 17708142

Prognosis

Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Schäfers HJ, Raddatz A, Schmied W, Takahashi H, Miura Y, Kunihara T, Aicher D
J Thorac Cardiovasc Surg 2015 Feb;149(2 Suppl):S30-6. Epub 2014 Sep 18 doi: 10.1016/j.jtcvs.2014.09.048. PMID: 25439784
Siu SC, Silversides CK
J Am Coll Cardiol 2010 Jun 22;55(25):2789-800. doi: 10.1016/j.jacc.2009.12.068. PMID: 20579534
Hsu YY, Kim S
Dent Clin North Am 1997 Jul;41(3):529-40. PMID: 9248689

Clinical prediction guides

Thiene G, Rizzo S, Basso C
Cardiovasc Pathol 2024 May-Jun;70:107604. Epub 2024 Jan 20 doi: 10.1016/j.carpath.2024.107604. PMID: 38253300
Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Ehrlich T, de Kerchove L, Vojacek J, Boodhwani M, El-Hamamsy I, De Paulis R, Lansac E, Bavaria JE, El Khoury G, Schäfers HJ
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):457-464. Epub 2020 May 5 doi: 10.1016/j.pcad.2020.04.010. PMID: 32380025
Otto CM
Heart 2018 Nov;104(22):1807-1809. doi: 10.1136/heartjnl-2018-314232. PMID: 30366931
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article

Recent systematic reviews

Guo X, Duan X
Clin Genet 2023 Sep;104(3):287-297. Epub 2023 Jul 13 doi: 10.1111/cge.14400. PMID: 37448157
Antonarakis GS, Palaska PK, Suri S
Orthod Craniofac Res 2017 Nov;20(4):216-226. Epub 2017 Oct 13 doi: 10.1111/ocr.12204. PMID: 29027749
Masri A, Svensson LG, Griffin BP, Desai MY
Heart 2017 Sep;103(17):1323-1330. Epub 2017 May 10 doi: 10.1136/heartjnl-2016-309916. PMID: 28490615
Poggio P, Cavallotti L, Songia P, Di Minno A, Ambrosino P, Mammana L, Parolari A, Alamanni F, Tremoli E, Di Minno MN
J Am Heart Assoc 2016 May 18;5(5) doi: 10.1161/JAHA.116.003200. PMID: 27194004Free PMC Article
Khalaf K, Miskelly J, Voge E, Macfarlane TV
J Orthod 2014 Dec;41(4):299-316. doi: 10.1179/1465313314Y.0000000116. PMID: 25404667

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