Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Helicobacter Infection

MedGen UID:: 86925
•Concept ID:: C0079487
•: Disease or Syndrome

Synonyms:

Helicobacter Infections; Infection, Helicobacter; Infections, Helicobacter

Definition

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease. [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVHelicobacter Infection

Clinical finding
- Finding by Cause
  - Infection
    - Bacterial Infections and Mycoses
      - Bacterial infectious disease
        Gram-negative bacterial infections
        Helicobacter Infection

Professional guidelines

PubMed

Treatment of Helicobacter pylori with nitazoxanide-containing regimens: a systematic review.

Lee S, Sneed GT, Brown JN
Infect Dis (Lond) 2020 Jun;52(6):381-390. Epub 2020 Jan 3 doi: 10.1080/23744235.2019.1708454. PMID: 31900002

A new approach to the management of uninvestigated dyspepsia in primary care.

Salihefendic N, Zildzic M, Cabric E
Med Arch 2015 Apr;69(2):133-4. Epub 2015 Apr 6 doi: 10.5455/medarh.2015.69.133-134. PMID: 26005267 Free PMC Article

Rationale in diagnosis and screening of atrophic gastritis with stomach-specific plasma biomarkers.

Agréus L, Kuipers EJ, Kupcinskas L, Malfertheiner P, Di Mario F, Leja M, Mahachai V, Yaron N, van Oijen M, Perez Perez G, Rugge M, Ronkainen J, Salaspuro M, Sipponen P, Sugano K, Sung J
Scand J Gastroenterol 2012 Feb;47(2):136-47. doi: 10.3109/00365521.2011.645501. PMID: 22242613 Free PMC Article

See all (8)

Recent clinical studies

Etiology

Dietary amelioration of Helicobacter infection.

Fahey JW, Stephenson KK, Wallace AJ
Nutr Res 2015 Jun;35(6):461-73. Epub 2015 Mar 6 doi: 10.1016/j.nutres.2015.03.001. PMID: 25799054 Free PMC Article

Stem cells in gastric cancer.

Zhao Y, Feng F, Zhou YN
World J Gastroenterol 2015 Jan 7;21(1):112-23. doi: 10.3748/wjg.v21.i1.112. PMID: 25574084 Free PMC Article

Carcinogenesis of Helicobacter pylori.

Correa P, Houghton J
Gastroenterology 2007 Aug;133(2):659-72. doi: 10.1053/j.gastro.2007.06.026. PMID: 17681184

Helicobacter and digestive malignancies.

Starzyñska T, Malfertheiner P
Helicobacter 2006 Oct;11 Suppl 1:32-5. doi: 10.1111/j.1478-405X.2006.00431.x. PMID: 16925609

Helicobacter infection and gastric neoplasia.

Peek RM Jr, Crabtree JE
J Pathol 2006 Jan;208(2):233-48. doi: 10.1002/path.1868. PMID: 16362989

See all (75)

Diagnosis

Helicobacter pylori infection and eye diseases: a systematic review.

Saccà SC, Vagge A, Pulliero A, Izzotti A
Medicine (Baltimore) 2014 Dec;93(28):e216. doi: 10.1097/MD.0000000000000216. PMID: 25526440 Free PMC Article

Rationale in diagnosis and screening of atrophic gastritis with stomach-specific plasma biomarkers.

Interplay between Helicobacter pylori and immune cells in immune pathogenesis of gastric inflammation and mucosal pathology.

Tsai HF, Hsu PN
Cell Mol Immunol 2010 Jul;7(4):255-9. Epub 2010 Mar 1 doi: 10.1038/cmi.2010.2. PMID: 20190789 Free PMC Article

Effects of Helicobacter infection on research: the case for eradication of Helicobacter from rodent research colonies.

Chichlowski M, Hale LP
Comp Med 2009 Feb;59(1):10-7. PMID: 19295050 Free PMC Article

Helicobacter pylori infection.

Vandenplas Y, Badriul H
Acta Paediatr Taiwan 1999 Jul-Aug;40(4):212-24. PMID: 10910617

See all (58)

Therapy

Other Helicobacters, gastric and gut microbiota.

Péré-Védrenne C, Flahou B, Loke MF, Ménard A, Vadivelu J
Helicobacter 2017 Sep;22 Suppl 1 doi: 10.1111/hel.12407. PMID: 28891140

Effects of Helicobacter infection on research: the case for eradication of Helicobacter from rodent research colonies.

Chichlowski M, Hale LP
Comp Med 2009 Feb;59(1):10-7. PMID: 19295050 Free PMC Article

Carcinogenesis of Helicobacter pylori.

Correa P, Houghton J
Gastroenterology 2007 Aug;133(2):659-72. doi: 10.1053/j.gastro.2007.06.026. PMID: 17681184

Inflammation, immunity, and vaccines for Helicobacter infection.

Permin H, Andersen LP
Helicobacter 2005;10 Suppl 1:21-5. doi: 10.1111/j.1523-5378.2005.00337.x. PMID: 16178967

Vaccines.

Lee A
Eur J Gastroenterol Hepatol 1999 Aug;11 Suppl 2:S75-9. PMID: 10503828

See all (49)

Prognosis

Involvement of non-Helicobacter pylori helicobacter infections in Helicobacter pylori-negative gastric MALT lymphoma pathogenesis and efficacy of eradication therapy.

Takigawa H, Yuge R, Masaki S, Otani R, Kadota H, Naito T, Hayashi R, Urabe Y, Oka S, Tanaka S, Chayama K, Kitadai Y
Gastric Cancer 2021 Jul;24(4):937-945. Epub 2021 Feb 27 doi: 10.1007/s10120-021-01172-x. PMID: 33638751

Atypical Lymphoid Proliferations and Clonality in Helicobacter-associated Inflammatory Infiltrates in Children.

Ju JY, Stelow EB, Mahadevan MS, Fan J, Aguilera NS
Am J Surg Pathol 2019 Oct;43(10):1361-1367. doi: 10.1097/PAS.0000000000001317. PMID: 31261290

Oxyntic atrophy, metaplasia, and gastric cancer.

Goldenring JR, Nam KT
Prog Mol Biol Transl Sci 2010;96:117-31. doi: 10.1016/B978-0-12-381280-3.00005-1. PMID: 21075342 Free PMC Article

Local and systemic antibody responses in humans with Helicobacter pylori infection.

Blanchard TG, Nedrud JG, Czinn SJ
Can J Gastroenterol 1999 Sep;13(7):591-4. doi: 10.1155/1999/142457. PMID: 10519957

Blood tests in the management of Helicobacter pylori infection. Italian Helicobacter pylori Study Group.

Vaira D, Holton J, Menegatti M, Landi F, Ricci C, Ali A, Gatta L, Farinelli S, Acciardi C, Massardi B, Miglioli M
Gut 1998 Jul;43 Suppl 1(Suppl 1):S39-46. doi: 10.1136/gut.43.2008.s39. PMID: 9764039 Free PMC Article

See all (20)

Clinical prediction guides

Analysis of Innate Immune Responses to Helicobacter pylori.

Chonwerawong M, Ferrero RL
Methods Mol Biol 2021;2283:191-214. doi: 10.1007/978-1-0716-1302-3_17. PMID: 33765319

Involvement of non-Helicobacter pylori helicobacter infections in Helicobacter pylori-negative gastric MALT lymphoma pathogenesis and efficacy of eradication therapy.

Effects of Helicobacter pylori on Levodopa Pharmacokinetics.

Nyholm D, Hellström PM
J Parkinsons Dis 2021;11(1):61-69. doi: 10.3233/JPD-202298. PMID: 33164946 Free PMC Article

Rodent models of Helicobacter infection, inflammation, and disease.

Zhang S, Moss SF
Methods Mol Biol 2012;921:89-98. doi: 10.1007/978-1-62703-005-2_12. PMID: 23015495 Free PMC Article

Are Helicobacter pylori and other Helicobacter species infection associated with human biliary lithiasis? A meta-analysis.

Zhou D, Zhang Y, Gong W, Mohamed SO, Ogbomo H, Wang X, Liu Y, Quan Z
PLoS One 2011;6(11):e27390. Epub 2011 Nov 8 doi: 10.1371/journal.pone.0027390. PMID: 22087306 Free PMC Article

See all (37)

Recent systematic reviews

Treatment of Helicobacter pylori with nitazoxanide-containing regimens: a systematic review.

Lee S, Sneed GT, Brown JN
Infect Dis (Lond) 2020 Jun;52(6):381-390. Epub 2020 Jan 3 doi: 10.1080/23744235.2019.1708454. PMID: 31900002

Helicobacter pylori infection and eye diseases: a systematic review.

Saccà SC, Vagge A, Pulliero A, Izzotti A
Medicine (Baltimore) 2014 Dec;93(28):e216. doi: 10.1097/MD.0000000000000216. PMID: 25526440 Free PMC Article

See all (2)

MedGen

National Center for Biotechnology Information