U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormality of the premaxilla

MedGen UID:
869285
•Concept ID:
C4023711
•
Anatomical Abnormality
Synonyms: Abnormality of the intermaxillary bone; Abnormality of the intermaxillary segment of the maxilla; Abnormality of the premaxillary bone; Abnormality of the primary palate bone
 
HPO: HP:0010758

Definition

An abnormality of the premaxilla, the most anterior part of the maxilla that usually bears the central and lateral incisors and includes the anterior nasal spine and inferior aspect of the piriform rim. The premaxilla contains the bone and teeth of the primary palate. [from HPO]

Professional guidelines

PubMed

Cleft Lip and Palate Midfacial Hypoplasia: Criteria to Choose the Treatment.
Fariña R, Lolas J, Moreno E, Alister JP, Uribe MF, Pantoja R, Valladares S, Arrué C
J Craniofac Surg 2022 Mar-Apr 01;33(2):496-501. doi: 10.1097/SCS.0000000000007973. PMID: 34261964
Management of the protuberant premaxilla: where does it fit in?
Morris L
Curr Opin Otolaryngol Head Neck Surg 2019 Aug;27(4):302-309. doi: 10.1097/MOO.0000000000000558. PMID: 31219831
Management of the premaxilla in the treatment of bilateral cleft of lip and palate: what can the literature tell us?
Bittermann GK, de Ruiter AP, Janssen NG, Bittermann AJ, van der Molen AM, van Es RJ, Rosenberg AJ, Koole R
Clin Oral Investig 2016 Mar;20(2):207-17. Epub 2015 Sep 16 doi: 10.1007/s00784-015-1589-y. PMID: 26374747Free PMC Article

Recent clinical studies

Etiology

Repair of Protruding Bilateral Cleft Lip and Palate With Staged Premaxilla Setback Osteotomy, Cheiloplasty, and Palatoplasty in Trisomy 17p Patient: A Review of Syndromic Clinical Characteristic.
Bangun K, Halim J, Tania V
Cleft Palate Craniofac J 2023 May;60(5):621-626. Epub 2021 Dec 30 doi: 10.1177/10556656211069820. PMID: 34967231
Primary Premaxillary Ostectomy and Setback: Dealing With the "Fly-away" Premaxilla.
Farhadi R, Wallace RD
Ann Plast Surg 2023 Apr 1;90(4):325-330. doi: 10.1097/SAP.0000000000001423. PMID: 29762437
The arrhinias: Proboscis lateralis literature review and surgical update.
Galiè M, Clauser LC, Tieghi R, Kawamoto HK, Wolfe SA, Bianchi AE
J Craniomaxillofac Surg 2019 Sep;47(9):1410-1413. Epub 2018 Dec 27 doi: 10.1016/j.jcms.2018.12.013. PMID: 31420283
Surgical Repositioning of the Premaxilla Using a Minimally Invasive Endonasal Approach.
Sierra NE, Ferrer-Fuertes A, Salazar-Perez B, Cho-Lee GY, Martí-Pages C, Rivera-Baró A, Rubio-Palau J, García-Diez EM
Cleft Palate Craniofac J 2018 Jul;55(6):830-836. Epub 2018 Feb 22 doi: 10.1597/16-057. PMID: 28140669
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Diagnosis

Premaxilla: an independent bone that can base therapeutics for middle third growth!
Trevizan M, Consolaro A
Dental Press J Orthod 2017 Mar-Apr;22(2):21-26. doi: 10.1590/2177-6709.22.2.021-026.oin. PMID: 28658352Free PMC Article
Traumatic Fracture of the Premaxilla in the Bilateral Cleft Patient.
Warren A, Applegren N, Muzaffar AR
J Craniofac Surg 2016 Oct;27(7):1719-1721. doi: 10.1097/SCS.0000000000002948. PMID: 27483099
Premaxillary Repositioning in the Severe Form of Bilateral Cleft Lip and Palate.
Koh KS, Han WY, Jeong WS, Oh TS, Kwon SM, Choi JW
J Craniofac Surg 2016 Sep;27(6):1440-4. doi: 10.1097/SCS.0000000000002729. PMID: 27300460
Syndromes with supernumerary teeth.
Lubinsky M, Kantaputra PN
Am J Med Genet A 2016 Oct;170(10):2611-6. Epub 2016 Jun 2 doi: 10.1002/ajmg.a.37763. PMID: 27250821
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Therapy

Strategies to Evaluate Bilateral Cleft Lip Treatment.
Ürményi GL, Felzemburgh VA, Fernandes EC, Peixoto ARLF
J Craniofac Surg 2018 Sep;29(6):1457-1462. doi: 10.1097/SCS.0000000000004712. PMID: 30028395
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381
Complications following orthognathic surgery for patients with cleft lip/palate: A systematic review.
Yamaguchi K, Lonic D, Lo LJ
J Formos Med Assoc 2016 Apr;115(4):269-77. Epub 2015 Dec 11 doi: 10.1016/j.jfma.2015.10.009. PMID: 26686426
Stabilization of premaxilla repositioned during secondary bone grafting in complete bilateral cleft lip and palate patients.
Behnia H, Mesgarzadeh A, Tehranchi A, Morad G, Samieerad S, Younessian F
J Craniofac Surg 2014 Jul;25(4):1554-7. doi: 10.1097/SCS.0000000000000865. PMID: 24926720
Pulp necrosis during septorhinoplasty.
Moradi S, Poursadegh M, Bakhshaee M, Bonyadimanesh R, Poursadegh V
Laryngoscope 2010 Apr;120(4):673-5. doi: 10.1002/lary.20820. PMID: 20205176

Prognosis

Incidence and morphology of the incisive suture in CT scanning of young children and human fetuses.
Nicol P, Elmaleh-Bergès M, Sadoine J, Slimani L, Vacher C
Surg Radiol Anat 2020 Sep;42(9):1057-1062. Epub 2020 Jun 20 doi: 10.1007/s00276-020-02521-8. PMID: 32564109
Presurgical Orthopedics Appliance: The Latham Technique.
Cruz C
Oral Maxillofac Surg Clin North Am 2016 May;28(2):161-8. doi: 10.1016/j.coms.2016.01.004. PMID: 27150303
The modified "Wunderer" osteotomy for stabilization of the cleft-premaxilla--a new operative technique.
Steinhäuser EW
J Craniomaxillofac Surg 2014 Jul;42(5):372-6. Epub 2014 Feb 18 doi: 10.1016/j.jcms.2014.02.002. PMID: 24630854
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Management of the prominent premaxilla in bilateral cleft lip and palate.
Aburezq H, Daskalogiannakis J, Forrest C
Cleft Palate Craniofac J 2006 Jan;43(1):92-5. doi: 10.1597/04-114r.1. PMID: 16405381

Clinical prediction guides

Premaxillary Repositioning in the Severe Form of Bilateral Cleft Lip and Palate.
Koh KS, Han WY, Jeong WS, Oh TS, Kwon SM, Choi JW
J Craniofac Surg 2016 Sep;27(6):1440-4. doi: 10.1097/SCS.0000000000002729. PMID: 27300460
Presurgical Orthopedics Appliance: The Latham Technique.
Cruz C
Oral Maxillofac Surg Clin North Am 2016 May;28(2):161-8. doi: 10.1016/j.coms.2016.01.004. PMID: 27150303
A re-evaluation of the premaxillary bone in humans.
Barteczko K, Jacob M
Anat Embryol (Berl) 2004 Mar;207(6):417-37. Epub 2004 Feb 4 doi: 10.1007/s00429-003-0366-x. PMID: 14760532
Development of the facial midline.
Carstens MH
J Craniofac Surg 2002 Jan;13(1):129-87; discussion 188-90. doi: 10.1097/00001665-200201000-00032. PMID: 11887012
Clinical observations of cleft lip and palate.
Precious DS, Delaire J
Oral Surg Oral Med Oral Pathol 1993 Feb;75(2):141-51. doi: 10.1016/0030-4220(93)90084-h. PMID: 8426712

Recent systematic reviews

What is the Effectiveness of Premaxilla Surgical Repositioning and its Stabilization Methods in Mixed Dentition Patients With Bilateral Cleft Lip and Palate?
Normande Neto HV, Oliveira-Neto OB, Ribeiro ILH, Andrade CS, Sales PHDH, Lima FJC
Cleft Palate Craniofac J 2023 Oct;60(10):1211-1219. Epub 2022 May 9 doi: 10.1177/10556656221096304. PMID: 35535395
Repair Sequence and Management of the Premaxilla in Patients With Bilateral Cleft Lip and Palate: A Systematic Review of the Literature.
Chang IA, Bassiri Gharb B, Papay FA, Rampazzo A
J Craniofac Surg 2022 Mar-Apr 01;33(2):421-425. doi: 10.1097/SCS.0000000000008184. PMID: 34560740
Complications following orthognathic surgery for patients with cleft lip/palate: A systematic review.
Yamaguchi K, Lonic D, Lo LJ
J Formos Med Assoc 2016 Apr;115(4):269-77. Epub 2015 Dec 11 doi: 10.1016/j.jfma.2015.10.009. PMID: 26686426

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...