U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Early cutaneous photosensitivity

MedGen UID:
870443
Concept ID:
C4024889
Finding
Synonym: Sun sensitivity occurring early in life
 
HPO: HP:0007396

Definition

Photosensitivity of the skin occurring early in life. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly cutaneous photosensitivity

Conditions with this feature

Cutaneous photosensitivity-lethal colitis syndrome
MedGen UID:
347455
Concept ID:
C1857449
Disease or Syndrome
A rare inflammatory bowel disease characterized by early cutaneous photosensitivity manifesting by sun-induced facial erythematous and vesicular lesions and severe recurent colitis which lead to untreatable diarrhea. There have been no further descriptions in the literature since 1991.

Professional guidelines

PubMed

Dickey AK, Naik H, Keel SB, Levy C, Beaven SW, Elmariah SB, Erwin AL, Goddu RJ, Hedstrom K, Leaf RK, Kazamel M, Mazepa M, Philpotts LL, Quigley J, Raef H, Rudnick SR, Saberi B, Thapar M, Ungar J, Wang B, Balwani M; Porphyrias Consortium of the Rare Diseases Clinical Research Network
J Am Acad Dermatol 2023 Dec;89(6):1227-1237. Epub 2022 Aug 27 doi: 10.1016/j.jaad.2022.08.036. PMID: 36041558Free PMC Article
Dowd MD
Pediatr Ann 2019 Jun 1;48(6):e213-e214. doi: 10.3928/19382359-20190520-02. PMID: 31185109
Hojyo-Tomoka MT, Vega-Memije ME, Cortes-Franco R, Domínguez-Soto L
Dermatol Ther 2003;16(1):40-4. doi: 10.1046/j.1529-8019.2003.01606.x. PMID: 12919125

Recent clinical studies

Etiology

Badja C, Momen S, Koh GCC, Boushaki S, Roumeliotis TI, Kozik Z, Jones I, Bousgouni V, Dias JML, Krokidis MG, Young J, Chen H, Yang M, Docquier F, Memari Y, Valcarcel-Zimenez L, Gupta K, Kong LR, Fawcett H, Robert F, Zhao S, Degasperi A, Kumar Y, Davies H, Harris R, Frezza C, Chatgilialoglu C, Sarkany R, Lehmann A, Bakal C, Choudhary J, Fassihi H, Nik-Zainal S
Cell Rep 2024 Jun 25;43(6):114243. Epub 2024 May 27 doi: 10.1016/j.celrep.2024.114243. PMID: 38805398
Lehmann J, Seebode C, Martens MC, Emmert S
Anticancer Res 2018 Feb;38(2):1159-1164. doi: 10.21873/anticanres.12335. PMID: 29374753
Lehmann AR, McGibbon D, Stefanini M
Orphanet J Rare Dis 2011 Nov 1;6:70. doi: 10.1186/1750-1172-6-70. PMID: 22044607Free PMC Article
Norgauer J, Idzko M, Panther E, Hellstern O, Herouy Y
Eur J Dermatol 2003 Jan-Feb;13(1):4-9. PMID: 12609773
Hoang MT, Friedlander SF
Curr Opin Pediatr 1999 Oct;11(5):464-70. doi: 10.1097/00008480-199910000-00016. PMID: 10555600

Diagnosis

Dickey AK, Naik H, Keel SB, Levy C, Beaven SW, Elmariah SB, Erwin AL, Goddu RJ, Hedstrom K, Leaf RK, Kazamel M, Mazepa M, Philpotts LL, Quigley J, Raef H, Rudnick SR, Saberi B, Thapar M, Ungar J, Wang B, Balwani M; Porphyrias Consortium of the Rare Diseases Clinical Research Network
J Am Acad Dermatol 2023 Dec;89(6):1227-1237. Epub 2022 Aug 27 doi: 10.1016/j.jaad.2022.08.036. PMID: 36041558Free PMC Article
Martens MC, Emmert S, Boeckmann L
Genes (Basel) 2021 Jul 29;12(8) doi: 10.3390/genes12081173. PMID: 34440347Free PMC Article
Lehmann J, Seebode C, Martens MC, Emmert S
Anticancer Res 2018 Feb;38(2):1159-1164. doi: 10.21873/anticanres.12335. PMID: 29374753
Ganesan A, Hanawalt P
Photochem Photobiol 2016 Jan-Feb;92(1):52-60. Epub 2015 Dec 16 doi: 10.1111/php.12542. PMID: 26481112Free PMC Article
Gerstenblith MR, Goldstein AM, Tucker MA
Hematol Oncol Clin North Am 2010 Oct;24(5):885-906. doi: 10.1016/j.hoc.2010.06.003. PMID: 20816579Free PMC Article

Therapy

Lehmann J, Seebode C, Martens MC, Emmert S
Anticancer Res 2018 Feb;38(2):1159-1164. doi: 10.21873/anticanres.12335. PMID: 29374753
Kuhn A, Wenzel J, Bijl M
Semin Immunopathol 2016 Jan;38(1):97-112. Epub 2015 Dec 4 doi: 10.1007/s00281-015-0550-0. PMID: 26637330
Gruber-Wackernagel A, Byrne SN, Wolf P
Dermatol Clin 2014 Jul;32(3):315-34, viii. doi: 10.1016/j.det.2014.03.012. PMID: 24891054
Hojyo-Tomoka MT, Vega-Memije ME, Cortes-Franco R, Domínguez-Soto L
Dermatol Ther 2003;16(1):40-4. doi: 10.1046/j.1529-8019.2003.01606.x. PMID: 12919125
Roelandts R
J Am Acad Dermatol 1993 Feb;28(2 Pt 1):240-9. doi: 10.1016/0190-9622(93)70034-q. PMID: 8432922

Prognosis

Lehmann J, Seebode C, Martens MC, Emmert S
Anticancer Res 2018 Feb;38(2):1159-1164. doi: 10.21873/anticanres.12335. PMID: 29374753
Chen L, Tsai TF
Br J Dermatol 2018 Apr;178(4):854-862. Epub 2018 Mar 2 doi: 10.1111/bjd.16083. PMID: 29072309
Black JO
Head Neck Pathol 2016 Jun;10(2):139-44. Epub 2016 Mar 14 doi: 10.1007/s12105-016-0707-8. PMID: 26975629Free PMC Article
Lehmann AR, McGibbon D, Stefanini M
Orphanet J Rare Dis 2011 Nov 1;6:70. doi: 10.1186/1750-1172-6-70. PMID: 22044607Free PMC Article
Hoang MT, Friedlander SF
Curr Opin Pediatr 1999 Oct;11(5):464-70. doi: 10.1097/00008480-199910000-00016. PMID: 10555600

Clinical prediction guides

Li Y, Wu J, Cao Z
Environ Sci Pollut Res Int 2023 Dec;30(58):122011-122023. Epub 2023 Nov 14 doi: 10.1007/s11356-023-30535-3. PMID: 37962759Free PMC Article
Chen L, Tsai TF
Br J Dermatol 2018 Apr;178(4):854-862. Epub 2018 Mar 2 doi: 10.1111/bjd.16083. PMID: 29072309
Kuhn A, Wenzel J, Bijl M
Semin Immunopathol 2016 Jan;38(1):97-112. Epub 2015 Dec 4 doi: 10.1007/s00281-015-0550-0. PMID: 26637330
Daya-Grosjean L
Adv Exp Med Biol 2008;637:19-27. doi: 10.1007/978-0-387-09599-8_3. PMID: 19181107
Salasche SJ
J Am Acad Dermatol 2000 Jan;42(1 Pt 2):4-7. doi: 10.1067/mjd.2000.103342. PMID: 10607349

Recent systematic reviews

Brambullo T, Colonna MR, Vindigni V, Piaserico S, Masciopinto G, Galeano M, Costa AL, Bassetto F
Biomed Res Int 2022;2022:8549532. Epub 2022 Jul 18 doi: 10.1155/2022/8549532. PMID: 35898688Free PMC Article
Aronovich A, Snast I, Lapidoth M, Leshem YA, Enk CD, Tal Y, Mimouni D, Hodak E, Levi A
Photodermatol Photoimmunol Photomed 2021 Sep;37(5):431-438. Epub 2021 Mar 27 doi: 10.1111/phpp.12677. PMID: 33738834
Noyman Y, Edel Y, Snast I, Sherman S, Kaftory R, Lapidoth M, Mimouni D, Hodak E, Levi A
Photodermatol Photoimmunol Photomed 2021 Sep;37(5):374-379. Epub 2021 Feb 21 doi: 10.1111/phpp.12667. PMID: 33556208
Medlin JL, Hansen KE, Fitz SR, Bartels CM
Semin Arthritis Rheum 2016 Jun;45(6):691-7. Epub 2016 Jan 21 doi: 10.1016/j.semarthrit.2016.01.004. PMID: 26972993Free PMC Article
Lava SA, Simonetti GD, Ragazzi M, Guarino Gubler S, Bianchetti MG
Br J Dermatol 2013 May;168(5):1066-72. doi: 10.1111/bjd.12197. PMID: 23374016

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...